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Displaying 1 - 5 of 5 Matching Records

Avian Flu Special: What's in the Medicine Cabinet? Show Full Record 1524

Source: Nature. 2005 May 26;435(7041):407-9
Resource Type(s): Journal (Articles)
Searchable Keywords: Animals Antiviral agents Avian influenza Enzymology Humans International policy Neuraminidase Orthomyxoviridae World Health Organization
Abstract: No abstract available.

Generic Susceptibility and Biological Characterization of Chronic Wasting Disease - Annual Report 16 Jun 2004 -15 June 2005 Show Full Record 1177

Source: Defense Technical Information Center (U.S.). Scientific and Technical Information Network
Resource Type(s): Management Plans and Reports
Searchable Keywords: Biochemistry Chronic wasting disease Deer Disease transmission Enzymology Genetics Hydrolases Prion protein
Abstract: From abstract (free full-text available): The goals of this proposal are to: (i) identify prion protein (Prnp) variability in the Wisconsin free-ranging white-tailed deer population, (ii) determine the frequency of these Prnp alleles in CWD-positive and -negative deer, (iii) characterize the effect of these allelic variations on the biochemical and biological properties of the CWD agent and iv) to determine the likelihood of CWD transmission to humans. Deer Prnp alleles have been sequenced from ...

Influenzavirus Neuraminidase and Neuraminidase-inhibition Test Procedures Show Full Record 1461

Source: Bulletin of the World Health Organization. 1973;48(2):199-202
Resource Type(s): Journal (Articles)
Searchable Keywords: Antigens Avian influenza Enzymology Hemagglutinins Neuraminidase Orthomyxoviridae
Abstract: From abstract (free full-text available): The adequate characterization of type A influenzaviruses requires the identification not only of the haemagglutinin but also of the neuraminidase. The neuraminidase-inhibition test, as performed in the two WHO international reference centres for influenza, is described and its use in other laboratories--particularly those collaborating in the WHO programme--is recommended.

Micro Neuraminidase-Inhibition Assay for Classification of Influenza A Virus Neuraminidases Show Full Record 1898

Source: Avian Diseases. 1983; 27(3): 745-750
Resource Type(s): Journal (Articles)
Searchable Keywords: Animals Avian influenza Enzymology Microbiology Orthomyxoviridae RNA Serology
Abstract: From abstract (free full-text available): A neuraminidase-inhibition (NI) assay performed in microtiter plates is described. This micro-NI assay is a modification of the NI assay recommended by the WHO. It reduces the quantity of reagents required and permits antigenic classification of many isolates simultaneously. To determine the accuracy and sensitivity of this micro-NI assay, 110 influenza A viruses, representing all subtypes, based upon the 9 known neuraminidases (NA), were classified by t...

Viral Polymerase Mediates Adaptation of an Avian Influenza Virus to a Mammalian Host Show Full Record 880

Source: Proceedings of the National Academy of Sciences of the United States of America. 2005 Dec 20;102(51):18590-5. Epub 2005 Dec 8
Resource Type(s): Journal (Articles)
Searchable Keywords: Birds Disease transmission Enzymology Influenza A Virus, H7N7 Subtype Influenza in birds Metabolism Pathogenicity Physiology Virology
Abstract: From abstract (free full-text available): Mammalian influenza viruses are descendants of avian strains that crossed the species barrier and underwent further adaptation. Since 1997 in southeast Asia, H5N1 highly pathogenic avian influenza viruses have been causing severe, even fatal disease in humans. Although no lineages of this subtype have been established until now, such repeated events may initiate a new pandemic. As a model of species transmission, we used the highly pathogenic avian influ...

Displaying 1 - 5 of 5 Matching Records

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