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A Common Surface Antigen in Influenza Viruses from Human and Avian Sources Show Full Record 1901
Source: Journal of General Virology. 1968 Sep;3(2):201-8. Resource Type(s): Journal (Articles) Searchable Keywords: Analysis aspects Antigens Avian influenza Hemagglutinins Humans Immunology Neuraminidase Orthomyxoviridae Species specificity Abstract: No abstract available.
A Multiplex RT-PCR for Detection of Type A influenza Virus and Differentiation of Avian H5, H7, and H9 Hemagglutinin Subtypes Show Full Record 1293
Source: Molecular and Cellular Probes. 2006 Mar 14; [Epub ahead of print] Resource Type(s): Journal (Articles) Searchable Keywords: Avian influenza Diagnosis Genetics Hemagglutinins Polymerase chain reaction Viral subtypes Abstract: From abstract (online abstract only): A multiplex reverse transcriptase-polymerase chain reaction (mRT-PCR) was developed and optimized for the detection of type A influenza virus; the assay simultaneously differentiates avian H5, H7 and H9 hemagglutinin subtypes. Four sets of specific oligonucleotide primers were used in this test for type A influenza virus, H5, H7 and H9 heamagglutinin subtypes. The mRT-PCR DNA products were visualized by gel electrophoresis and consisted of fragments of 860bp...
A One-Size-Fits-All Flu Vaccine? Show Full Record 1911
Source: Science. 2006 Apr 21;312(5772):380-2. Resource Type(s): Journal (Articles) Searchable Keywords: Animals Antibodies Antigenic variation Avian influenza Clinical trials Hemagglutinins Humans Immunology Influenza A Virus Mice Nucleoproteins Orthomyxoviridae infections Prevention & control Proteins RNA Vaccines Abstract: No abstract available.
An Arg-Lys Insertion at the Hemagglutinin Cleavage Site of an H5N2 Avian Influenza Isolate Show Full Record 778
Source: Virus Genes. 1996;12(1):77-84. Resource Type(s): Journal (Articles) Searchable Keywords: Avian influenza Genetics Hemagglutinins Influenza A Virus, H5N2 subtype Abstract: From abstract (online abstract only): Recent isolations of H5N2 subtype avian influenza (AI) viruses in North America have raised questions concerning their origin, transmission to commercial poultry, and potential for virulence. One ratite-origin isolate of low pathogenicity, A/emu/TX/39924/93 (H5N2), was subjected to a procedure that rapidly selects and/or amplifies highly pathogenic (HP) strains. The resulting highly virulent derivative had an altered hemagglutinin (HA) gene containing an add...
Antigenic and Genetic Conservation of H3 Influenza Virus in Wild Ducks Show Full Record 1871
Source: Virology. 1987 Jul;159(1):109-19. Resource Type(s): Journal (Articles) Searchable Keywords: Amino acid sequence Animals Antibodies Avian influenza Base sequence Comparative studies Ducks Hemagglutinins Humans Immunology Influenza A Virus Japan Microbiology Abstract: From abstract (online abstract only): The hemagglutinins of H3 influenza viruses isolated from migratory ducks on the Pacific flyway in Japan during the period 1977 to 1985 were analyzed antigenically and genetically. Antigenic analysis using monoclonal antibodies to the hemagglutinins of A/Aichi/2/68 (H3N2) and A/duck/Hokkaido/8/80 (H3N8) viruses showed that antigenic drift occurred extensively in human strains, whereas the hemagglutinins of duck viruses were highly conserved. It was also found...
Avian Flu: Multiple Introductions of H5N1 in Nigeria Show Full Record 1930
Source: Nature. 2006 Jul 6;442(7098):37. Resource Type(s): Journal (Articles) Searchable Keywords: Agriculture Animals Asia Avian influenza Disease transmission Europe Genetics Hemagglutinins Influenza A Virus, H5N1Subtype Influenza in birds Isolation & purification Migration (animal) Nigeria Phylogeny Poultry Russia Virology Abstract: From abstract (online abstract only): As the avian influenza virus H5N1 swept from Asia across Russia to Europe, Nigeria was the first country in Africa to report the emergence of this highly pathogenic virus. Here we analyse H5N1 sequences in poultry from two different farms in Lagos state and find that three H5N1 lineages were independently introduced through routes that coincide with the flight paths of migratory birds, although independent trade imports cannot be excluded.
Avian Influenza Antibody Detection by Immunodiffusion Show Full Record 1689
Source: Avian Diseases. 1970 May;14(2):337-41. Resource Type(s): Journal (Articles) Searchable Keywords: Animals Antibodies Antigens Avian influenza Chickens Diagnosis Hemagglutinins Orthomyxoviridae Poultry diseases Turkeys Abstract: From abstract (free full-text available): Convalescent levels of influenza antibodies were demonstrated by an agar gel precipitin (AGP) test in turkey sera after field out-breaks. The AGP test was positive with chicken sera for at least 8 weeks after laboratory exposure to any of 3 influenza strains, and positive with turkey sera for at least 12 weeks after exposure. The AGP test facilitates a diagnosis of avian influenza using a suspect virus or paired sera without the influences of strain-to-s...
Changes in the Haemagglutinin and the Neuraminidase Genes Prior to the Emergence of Highly Pathogenic H7N1 Avian Influenza Viruses in Italy Show Full Record 1519
Source: Archives of Virology. 2001;146(5):963-73 Resource Type(s): Journal (Articles) Searchable Keywords: Amino acid sequence Animals Avian influenza Birds Chickens Comparative studies Genes Genetics Hemagglutinins Influenza A Virus Influenza in birds Italy Molecular structure Neuraminidase Outbreaks Poultry diseases Proteins Turkeys Virology Abstract: From abstract (online abstract only): Outbreaks of avian influenza due to an H7N1 virus of low pathogenicity occurred in domestic poultry in northern Italy from March 1999 until December 1999 when a highly pathogenic avian influenza (HPAI) virus emerged. Nucleotide sequences were determined for the HA1 and the stalk region of the neuraminidase (NA) for viruses from the outbreaks. The HPAI viruses have an unusual multibasic haemagglutinin (HA) cleavage site motif, PEIPKGSRVRRGLF. Phylogenetic ana...
Characterization of a Novel Influenza A Virus Hemagglutinin Subtype (H16) Obtained from Black-headed Gulls Show Full Record 1456
Source: Journal of Virology. 2005 Mar;79(5):2814-22 Resource Type(s): Journal (Articles) Searchable Keywords: Amino acid sequence Animals Avian influenza DNA Europe Genes Hemagglutinins Immunology Influenza A Virus Isolation & purification Molecular structure Sweden Virology Abstract: From abstract (free full-text available): In wild aquatic birds and poultry around the world, influenza A viruses carrying 15 antigenic subtypes of hemagglutinin (HA) and 9 antigenic subtypes of neuraminidase (NA) have been described. Here we describe a previously unidentified antigenic subtype of HA (H16), detected in viruses circulating in black-headed gulls in Sweden. In agreement with established criteria for the definition of antigenic subtypes, hemagglutination inhibition assays and immuno...
Characterization of a Novel Influenza Hemagglutinin, H15: Criteria for Determination of Influenza A Subtypes Show Full Record 1865
Source: Virology. 1996 Mar 15;217(2):508-16. Resource Type(s): Journal (Articles) Searchable Keywords: Amino acid sequence Antigens Avian influenza Comparative studies Genes Hemagglutinins Immunology Influenza A Virus Molecular structure Phylogeny RNA Viral proteins Abstract: From abstract (online abstract only): Two viruses with a novel hemagglutinin (HA), A/duck/Australia/341/83 and A/shearwater/West Australia/2576/79, have been isolated from a duck and a shorebird in Australia. Hemagglutination inhibition and double immunodiffusion assays failed to reveal cross-reactivity with any of the known subtypes (H1 to H14). We therefore propose that these viruses constitute a new HA subtype, H15. Sequence analysis of the HA genes confirmed the serologic findings. When comp... |
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