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The Genome Reference Consortium

Putting sequences into a chromosome context.

The original model for representing the genome assemblies was to use a single, preferred tiling path to produce a single consensus representation of the genome. Subsequent analysis has shown that for most mammalian genomes a single tiling path is insufficient to represent a genome in regions with complex allelic diversity. The GRC is now working to create assemblies that better represent this diversity and provide more robust substrates for genome analysis.

We are planning to update the human reference assembly to GRCh38 in the summer of 2013. If you have questions or concerns about this let us know.

See our blog for more information on why we think this is important.

We are planning to update the zebrafish reference assembly to GRCz10 in late 2013. If you have questions or concerns about this let us know.

Page last updated: Apr 16, 2012