Technologies Available for Licensing

Current and Past Licensees of NHGRI Technologies

Patented and Patent-Pending Technologies

• Latrophilin 3, a Gene Involved in Attention Deficit Hyperactivity Disorder (ADHD)
  DHHS Reference Nos.: E-312-2006 and E-187-2011
  U.S. Patent 8,003,406 issued August 23, 2011
  US. Provisional Patent Application 61/505,864 filed July 8, 2011
  Lead Inventor: Maximillian Muenke, M.D. (NHGRI)
  Marketing Description: Latrophilin 3, a Gene Involved in Attention Deficit Hyperactivity Disorder (ADHD)
  Office of Technology Transfer Abstract
  Federal Register Publication
  
  
• Use of Adenosine Agonists to Prevent Vascular Calcification Disorders
  DHHS Reference No.: E-094-2010
  PCT Application PCT/US2011/030493 filed March 30, 2011
  Lead Inventor: William A. Gahl, M.D., Ph.D. (NHGRI)
  Marketing Description: Use of Adenosine Agonists to Prevent Vascular Calcification Disorders
  Office of Technology Transfer Abstract
  
  
• Device and Method for Direct Measurement of In Vivo Oxidation
  DHHS Reference No.: E-099-2009
  U.S. Patent Application 12/418,795 filed April 6, 2009
  Lead Inventor: Charles P. Venditti, M.D., Ph.D. (NHGRI)
  Marketing Description: Device and Method for Direct Measurement of In Vivo Oxidation
  Office of Technology Transfer Abstract
  
  
• Use of Genetic Polymorphisms to Assess Risk of Pregnancy Complications, Miscarriage, and of Bearing Children with Birth Defects
  DHHS Reference No.: E-149-2005
  U.S. Patent 7,879,551 issued February 1, 2011
  U.S. Patent Application 13/008,528 filed January 18, 2011
  Lead Inventor: Lawrence C. Brody, Ph.D. (NHGRI)
  Office of Technology Transfer Abstract
  Federal Register Publication
  
  
• Tissue Microarrays for Rapid Molecular Profiling
  DHHS Reference Nos.: E-002-1998, E-007-1999, E-272-1999, E-273-1999, and E-274-1999
  U.S. Patent No. 6,699,710 issued March 2, 2004
  U.S. Patent No. 6,905,823 issued June 14, 2005
  Lead Inventor: Olli Kallioniemi, M.D., Ph.D.
  Marketing Description: Tissue Microarrays For Rapid Molecular Profiling
  Federal Register Description
  
  
• LMNA Gene and Its Involvement in Hutchinson-Gilford Progeria Syndrome (HGPS) and Arteriosclerosis
  DHHS Reference No.: E-020-2003
  U.S. Patent 7,297,492 issued November 29, 2007
  U.S. Patent Application 11/870,234 allowed June 12, 2011
  Lead Inventors: B. Maria H. Eriksson, Ph.D. and Francis S. Collins, M.D., Ph.D. (NHGRI)
  Marketing Description: LMNA Gene and Its Involvement in Hutchinson-Gilford Progeria Syndrome (HGPS) and Arteriosclerosis
  Office of Technology Transfer Abstract
  Federal Register Publication
  News Release
  
  
• Farnesyltransferase Inhibitors for Treatment of Laminopathies, Cellular Aging and Atherosclerosis
  DHHS Reference No.: E-055-2005
  U.S. Patent 7,838,531 issued November 23, 2010
  U.S. Patent Application 12/905,838 filed October 15, 2010
  Lead Inventors: Leslie B. Gordon, M.D., Ph.D. (Progeria Research Foundation) and Francis S. Collins, M.D., Ph.D. (NHGRI)
  Marketing Description: Farnesyltransferase Inhibitors for Treatment of Laminopathies, Cellular Aging and Atherosclerosis
  Office of Technology Transfer Abstract
  Federal Register Description
  
  
• Gene Mutation for Parkinson's Disease
  DHHS Reference No.: E-190-1997
  U.S. Patent 7,001,720 issued February 21, 2006
  Lead Inventor: Mihael H. Polymeropoulos, M.D. (NHGRI)
  Office of Technology Transfer Abstract
  News Release
  
  
• Gene for Multiple Endocrine Neoplasia Type 1 (MEN1)
  DHHS Reference No.: E-094-1997
  U.S. Patent 7,358,347 issued April 15, 2008
  Lead Inventors: Settara Chandrasekharappa, Ph.D. (NHGRI) and Francis S. Collins, M.D., Ph.D. (NHGRI)
  Office of Technology Transfer Abstract
  News Release
  
  
• Methods for Detecting Cervical Cancer
  DHHS Reference No.: E-012-1997
  U.S. Patent 5,919,624 issued July 6, 1999
  Lead Inventor: Thomas K. Ried, M.D.
  
  
• AIB1, A Novel Steroid Receptor Co-Activator Amplified in Human Breast Cancer
  DHHS Reference No.: E-018-1997
  U.S. Patent 6,562,589 issued May 13, 2003
  U.S. Patent 7,232,890 issued June 19, 2007
  Lead Inventor: Paul Meltzer, M.D., Ph.D. (NHGRI)
  Office of Technology Transfer Abstract
  News Release
  
  

Research Materials

Mouse Models

• Mouse Model of Hutchinson-Gilford Progeria Syndrome and Vascular Abnormalities
  DHHS Reference No.: E-243-2011; Research Material
  Lead Inventors: Michael R. Erdos (NHGRI) and Francis S. Collins, M.D., Ph.D. (NHGRI)
  Marketing Description: Mouse Model of Hutchinson-Gilford Progeria Syndrome and Vascular Abnormalities
  
  
• Murine Model of Niemann-Pick C Disease
  DHHS Reference No: E-004-2011/0; Research Materials
  Lead Inventor: William J. Pavan Ph.D. (NHGRI)
  Marketing Description: Pamela L. Schwartzberg, M.D., Ph.D. (NHGRI)
  Marketing Description: Murine C57BL/6J Embryonic Stem Cell Lines Generated Using Serum-Free Media
  Office of Technology Transfer Abstract
  
  
• SAP/SH2D1A Knockout Mice: A Model for X-linked Lymphoproliferative Disease
  DHHS Reference No.: E-343-2003; Research Materials
  Lead Inventor: Pamela L. Schwartzberg, M.D., Ph.D. (NHGRI)
  Marketing Description: SAP/SH2D1A Knockout Mice: A Model for X-linked Lymphoproliferative Disease
  Office of Technology Transfer Abstract
  Federal Register Description
  
  
• Tec Kinase Deficient Mice
  DHHS Reference Nos.: E-178-2003/0 and E-178-2003/1; Research Materials
  Lead Inventor: Pamela L. Schwartzberg, M.D., Ph.D. (NHGRI)
  Marketing Description: Tec Kinase Deficient Mice
  Office of Technology Transfer Abstract
  Federal Register Description
  
  

Other Research Materials

• Human Melanoma Cell Lines with ERBB4 Mutations
  DHHS Reference No.: E-229-2010; Research Materials
  Lead Inventor: Yardena Samuels, Ph.D. (NHGRI)
  Marketing Description: Human Melanoma Cell Lines with ERBB4 Mutations
  Office of Technology Transfer Abstract
  
  
• Human Melanoma Metastasis Cell Line with Isocitrate Dehydrogenase (IDH1) R132 Mutation
  DHHS Reference No.: E-232-2010; Research Materials
  Lead Inventor: Yardena Samuels, Ph.D.(NHGRI)
  Marketing Description: Human Melanoma Metastasis Cell Line with Isocitrate Dehydrogenase (IDH1) R132 Mutation
  Office of Technology Transfer Abstract
  
  
• Novel Genotoxic Detection Assays
  DHHS Reference Nos.: E-215-2010 and E-108-2008; Research Materials
  Lead Inventor: Kyungjae Myung, Ph.D. (NHGRI)
  Marketing Description: Novel Genotoxic Detection Assays
  
  
• Neural Crest-Melanocyte cDNA Based Microarray Analysis for Human Skin Pigmentation Research
  DHHS Reference No.: E-014-2002; Research Materials
  Inventors: William Pavan, Ph.D. (NHGRI) and Stacie K. Loftus, Ph.D. (NHGRI)
  Office of Technology Transfer Abstract
  Federal Register Publication
  
  
• Monoclonal Antibody to the Protein NCOA6 (Also Called ASC-2 and AIB-3)
  DHHS Reference No.: E-168-2005; Research Materials
  Lead Inventor: Paul S. Meltzer, M.D., Ph.D. (NHGRI)
  Office of Technology Transfer Abstract
  Federal Register Description
  
  

For information on collaborative research opportunities and/or NHGRI technologies available for licensing, contact:

Claire T. Driscoll
Director, Technology Transfer Office
E-mail: cdriscol@mail.nih.gov

Anna Solowiej, Ph.D., J.D.
Technology Transfer Specialist
E-mail: solowieja@mail.nih.gov

Address for First Class Mail

Technology Transfer Office
National Human Genome Research Institute (NHGRI)
National Institutes of Health (NIH)
5635 Fishers Lane, Suite 3058, MSC 9307
Bethesda, MD 20892-9307
Phone: (301) 402-2537
Fax: (301) 402-9722

Address for Courier Deliveries (FedEx, UPS, etc.)

Technology Transfer Office
National Human Genome Research Institute (NHGRI)
National Institutes of Health (NIH)
5635 Fishers Lane, Suite 3058
Rockville, MD 20852

To view the PDF document(s) on this page, you will need Adobe Reader.

Top of page

Last Updated: June 22, 2012