(202) 234-4433 Neal R. Gross & Co., Inc. Page 1 UNITED STATES OF AMERICA DEPARTMENT OF AGRICULTURE AND DEPARTMENT OF HEALTH AND HUMAN SERVICES DIETARY GUIDELINES ADVISORY COMMITTEE THIRD MEETING WEDNESDAY, APRIL 29, 2009 The meeting came to order at 1:30 p.m., Dr. Linda Van Horn, Chairperson, presiding. PRESENT: LINDA V. VAN HORN, PHD, RD, LD CHAIR NAOMI K. FUKAGAWA, MD, PHD VICE CHAIR CHERYL ACHTERBERG, PHD MEMBER LAWRENCE J. APPEL, MD, MPH MEMBER ROGER A. CLEMENS, DRPH, MEMBER MIRIAM E. NELSON, PHD MEMBER SHARON M. NICKOLS-RICHARDSON, PHD MEMBER THOMAS A. PEARSON, MD, PHD, RD MEMBER RAFAEL PEREZ-ESCAMILLA, PHD MEMBER XAVIER PI-SUNYER, MD, MPH MEMBER ERIC B. RIMM, SCD MEMBER JOANNE L. SLAVIN, PHD, RD MEMBER CHRISTINE L. WILLIAMS, MD, MPH MEMBER ALSO PRESENT: CAROLE DAVIS, CO-EXECUTIVE SECRETARY AND DFO, USDA KATHRYN McMURRY, CO-EXECUTIVE SECRETARY, DHHS RADM PENELOPE SLADE-SAWYER, PT, MSW, DHHS (202) 234-4433 Neal R. Gross & Co., Inc. Page 2 TABLE OF CONTENTS PAGE Opening Remarks 3 Expert Presentations Adam Drewnowski 12 Frank Sacks 60 Patricia Crawford 102 Michael Hamm 135 Food Safety and Technology 175 Recess 214 (202) 234-4433 Neal R. Gross & Co., Inc. Page 3 1 P R O C E E D I N G S 2 (1:30 p.m.) 3 MS. DAVIS: Ladies and gentlemen, 4 good afternoon from Washington, D.C. Thank 5 you for standing by. I'm Carole Davis, the 6 Designated Federal Officer, and a USDA Co- 7 Executive Secretary to the Dietary Guidance 8 Advisory Committee. 9 I'm speaking on behalf of Dr. 10 Robert Post, who could not be here with us 11 today. Dr. Post is the Acting Executive 12 Director of the Center for Nutrition Policy 13 and Promotion of the United States Department 14 of Agriculture. 15 At this time, I would like to 16 recognize Rear Admiral Penny Slade-Sawyer 17 representing our partnership with the U.S. 18 Department of Health and Human Services in 19 working with the Committee. 20 We want to welcome you to this 21 webinar for the third meeting of the 2010 22 Dietary Guidance Advisory Committee. I would (202) 234-4433 Neal R. Gross & Co., Inc. Page 4 1 like to give you a few reminders before we get 2 started. 3 This Committee is governed by the 4 Federal Advisory Committee Act or FACA. FACA 5 was established to assure that Advisory 6 Committees provide advice that is relevant, 7 objective, and open to the public, act 8 promptly to complete their work, and comply 9 with reasonable cost controls and 10 recordkeeping requirements. 11 Therefore, each public meeting has 12 been and will continue to be announced in the 13 Federal Register through a public notice. 14 As part of the open and 15 transparent process, the meetings of the full 16 Committee are open for observation by the 17 public. And any deliberations that occur 18 between meetings such as those in topic- 19 specific subcommittees are brought back to the 20 full Committee at a public meeting as you will 21 hear today and tomorrow. 22 During the meeting all public (202) 234-4433 Neal R. Gross & Co., Inc. Page 5 1 participants will be in a listen-only mode. 2 The public has opportunities to participate in 3 the process by providing written comments to 4 the Committee through our online database at 5 www.dietaryguidelines.gov. 6 In addition to the rules of the 7 FACA, I would like to review some rules of 8 engagement for the Committee. The Dietary 9 Guidelines Advisory Committee members will 10 refer any individuals who contact them 11 personally to solicit information about their 12 work on the Committee to the Dietary 13 Guidelines Management Team. 14 Committee members are not able to 15 give presentations as a member of the 16 Committee about the Committee's work or speak 17 as a representative of the Committee as this 18 would be inconsistent with Advisory Committee 19 operations and would preclude the requirement 20 that the Committee's work is transparent to 21 the public. 22 We are very excited to be (202) 234-4433 Neal R. Gross & Co., Inc. Page 6 1 broadcasting this message live via the web. 2 This new medium enables us to reach a more 3 varied audience of interested parties. We 4 have individuals from across the nation as 5 well as internationally participating today 6 and tomorrow. 7 I would like to review a few 8 technical points for the public. On your 9 screen, you see some relevant information. If 10 you experience technical difficulties, you may 11 contact WebEx Technical Support toll free at 12 1-866-229-3239. This information was also e- 13 mailed to all registrants as well as was a 14 technical assistance number for our 15 international participants. 16 The event staff here in the room 17 with us will be monitoring an e-mail line, so 18 to speak, where public participants can send 19 notes of any technical difficulties while the 20 meeting proceeds. As you see on the screen, 21 this e-mail address is tech_issue@yahoo.com. 22 So please note that the staff will not respond (202) 234-4433 Neal R. Gross & Co., Inc. Page 7 1 to these e-mails. It is simply one of several 2 ways we are monitoring the streaming 3 efficiency of the meeting to the public. 4 This presentation is being 5 recorded. It will be available for replay for 6 approximately a year. All registrants will 7 receive information following the meeting 8 about how to access the archive. 9 After the meeting, you can also 10 visit our website, www.dietaryguidelines.gov 11 to request the archive. 12 We value your feedback on this 13 webinar meeting and after the meeting, 14 registrants will receive a follow-up survey. 15 As in that past, a transcript and 16 a written summary of this event will also be 17 posted to our website when available. 18 Because this meeting is being 19 streamed live to the public, I would like to 20 ask that the Committee members clearly state 21 their name before speaking. This is 22 particularly important to facilitate clear (202) 234-4433 Neal R. Gross & Co., Inc. Page 8 1 deliberations to the public who are following 2 the discussion. 3 With that said, I'd now like to 4 turn the meeting over to the Chair of the 5 Dietary Guidelines Advisory Committee, Dr. 6 Linda Van Horn. 7 CHAIR VAN HORN: Thank you, 8 Carole. And this is Linda Van Horn. And I 9 would like to offer my welcome and thanks for 10 participation to the Committee as well as 11 those who support the Committee. And good 12 afternoon to our public participants who are 13 viewing on the internet today. 14 Since the second meeting of the 15 Dietary Guidelines Advisory Committee in late 16 January, the Committee has met several 17 milestones. Each of the seven topic area 18 subcommittees has prioritized their research 19 questions for scientific review of the 20 literature. 21 We also identified several areas 22 where outside expertise is needed. And we are (202) 234-4433 Neal R. Gross & Co., Inc. Page 9 1 going to hear from those experts today and 2 tomorrow. 3 Each subcommittee has been 4 diligently working to move their scientific 5 reviews forward by gathering pertinent 6 information and clarifying their review plans. 7 In some areas, literature reviews have 8 already been completed and that information is 9 now being extracted and organized. 10 We will hear an update on the 11 status of their work from each of the seven 12 subcommittees over the course of the next two 13 days. Our Food Safety and Technology 14 Subcommittee will present later today and the 15 remaining six groups tomorrow. 16 We continue to have lively 17 discussions on several cross-cutting issues, 18 which we will cover throughout this meeting as 19 well as during the time that has been set 20 aside at the end of the day tomorrow. 21 To remind the Committee members, 22 because this meeting is open to the public, (202) 234-4433 Neal R. Gross & Co., Inc. Page 10 1 again, please introduce yourself when you are 2 speaking so people can become familiar with 3 your voices. 4 We're on a very tight timeline 5 today and tomorrow so we're going to do our 6 best to stay on that timeline to be important 7 in assisting the public in following along 8 with this agenda. 9 With that, I'd like to plunge 10 right in to today's agenda. This afternoon, 11 we have the benefit of hearing from four 12 individuals on topics where the Committee felt 13 outside expertise would be highly valuable. 14 And I'd like to pay special thanks to these 15 four presenters who, on relatively short 16 notice, agreed to be here with us today. And 17 we truly appreciate this time and energy. 18 Our first presenter is Dr. Adam 19 Drewnowski. He is a world-renowned leader in 20 innovative research approaches for the 21 prevention and treatment of obesity. 22 He is the Director of the (202) 234-4433 Neal R. Gross & Co., Inc. Page 11 1 Nutritional Sciences Program at the University 2 of Washington in Seattle and Professor of 3 Epidemiology with an adjunct appointment in 4 medicine and is a joint member of the Fred 5 Hutchinson Cancer Research Center. 6 Dr. Drewnowski is also Director of 7 the Center for Public Health and Nutrition and 8 the Center for Obesity Research. 9 Dr. Drewnowski's current research 10 is focused on the relationship between poverty 11 and obesity and the links between obesity and 12 diabetes rates in vulnerable populations and 13 access to those healthy foods. 14 He has conducted extensive studies 15 on taste function and food preferences in 16 relation to food choices and the overall 17 quality of the diet and has also conducted 18 epidemiological studies on dietary quality 19 both in the United States and abroad. 20 We are very grateful for your 21 willingness to join us here today. Thank you 22 and please begin. (202) 234-4433 Neal R. Gross & Co., Inc. Page 12 1 DR. DREWNOWSKI: Thank you. 2 Good afternoon everyone. I want 3 to express my thanks to the Committee for 4 inviting me here to share my thoughts about 5 food, health and incomes. And to present 6 evidence on the economics of food choice 7 behavior in satiety that I hope will help 8 guide your deliberations in the future. 9 I think this is a historic 10 occasion. I think this Committee really has 11 unprecedented power to change the way that 12 Americans think about food, purchase food, and 13 use food to create healthier diets. But with 14 power comes challenges. And this Committee 15 faces also an unprecedented challenge. 16 I think in the past, many 17 committees looked at scientific evidence and 18 tried to point the way to healthiest, most 19 nutritious, most nutrient-dense foods. 20 The economic crisis has really 21 changed all that. There are many people 22 sliding into poverty. There are people trying (202) 234-4433 Neal R. Gross & Co., Inc. Page 13 1 to make ends meet. There are people who 2 cannot afford many of the foods that are 3 recommended. What are we to do about them? 4 So we need to think not only about 5 nutrient-dense foods. This is a given. We 6 need to think about affordable nutrient-dense 7 foods and how they can be used by all segments 8 of the population to build healthier diets. 9 So I would like to bring a variety 10 of evidence to support my views. But I want 11 to start with full disclosure. 12 My research on food prices has 13 been funded by the U.S. Department of 14 Agriculture. 15 My research on diet quality and 16 diet cost was funded by the National 17 Institutes of Health and by the French 18 government. 19 Research on affordable nutrient- 20 dense foods has been funded by the Nutrient- 21 Rich Foods Coalition. 22 And research on satiety, which I (202) 234-4433 Neal R. Gross & Co., Inc. Page 14 1 was asked to talk about as well, was funded by 2 a variety of industry sources both national 3 and international, Danone France, Sudzucker 4 Germany, General Mills, and the American 5 Beverage Association and the American Beverage 6 Institute. 7 I am about to answer the 8 Committee's five questions. I took the 9 liberty of rearranging them in the reverse 10 order because the fundamental question really 11 is: Is it possible to improve diet quality 12 while maintaining lower a diet cost? 13 And then I have evidence to show 14 the relation between food prices and diet 15 quality, further evidence to demonstrate links 16 between food costs, poverty, and obesity 17 because it is actually possible to be hungry 18 and overweight. It is not a contradiction in 19 terms. 20 And then I want to deal with the 21 relation between specific macronutrients, 22 sugar and fat, health outcomes, and body (202) 234-4433 Neal R. Gross & Co., Inc. Page 15 1 weight. 2 And then one question that was 3 asked whether or not sugars, especially in 4 liquid form, contribute to obesity and is the 5 amount or the type of sugar responsible in 6 increasing national obesity rates. So I'll 7 deal with that issue as well. 8 But I want to take the broader 9 picture here. As you obviously realized, food 10 choices are driven by a variety of factors. 11 Yes, we do have taste, cost, and convenience. 12 Any marketer will tell you that. But there 13 are a number of other factors that come in. 14 Some segments of our society are 15 acutely sensitive to the issue of money, time, 16 and access. Simply, some foods are too dear, 17 not accessible, not available in given 18 neighborhoods. What are we to do to change 19 all that? 20 And then I say it with some regret 21 as a public health nutritionist, not enough 22 people have nutrition knowledge concerned with (202) 234-4433 Neal R. Gross & Co., Inc. Page 16 1 health or let's not forget cooking skills. So 2 nutrition advice and dietary guidelines are a 3 hugely important part of the picture but we 4 need to take other factors, notably incomes 5 and prices and so on, into account. 6 And the various experts presenting 7 here today and coming in tomorrow will address 8 those issues. I'm actually encouraged that 9 the Committee is taking these broader issues 10 into consideration. 11 So this is my logic flow. This is 12 what my research shows. Research shows that 13 energy-dense foods, energy density defined as 14 calories per 100 grams, actually cost less per 15 calorie. They are cheap sources of calories. 16 They may be cheap sources of empty calories - 17 - more about that later -- but they are 18 certainly cheap sources of calories. 19 Such foods may contain added 20 sugars and added fats. Diets composed of such 21 foods are cheaper. It is not too much of a 22 leap to suggest that such diets are not only (202) 234-4433 Neal R. Gross & Co., Inc. Page 17 1 cheaper but they are preferentially selected 2 by lower income groups who are obese and 3 increasing diabetic and increasing suffering 4 from metabolic syndrome. 5 So you see a connection here 6 between energy density of foods, food prices 7 per calorie, energy cost, the quality of the 8 diet, the type of the diet selected by given 9 consumers. And then, not surprising, poverty 10 and obesity are very closely linked. 11 So to support my viewpoint, I'm 12 going to use data from the U.S. Department of 13 Agriculture. And I actually I commend the 14 USDA for having come up with two datasets, 15 which I have been analyzing for the past year. 16 First of all, I have been using 17 the Food and Nutrition Database for Dietary 18 Studies, which lists nutrient composition of 19 all foods consumed by Americans in the 20 National Health and Nutrition Examination 21 Survey. This is the dataset for what we eat 22 in America, an exhaustive, good quality, (202) 234-4433 Neal R. Gross & Co., Inc. Page 18 1 nutrient composition dataset from the USDA. 2 And then last year, the Center for 3 Nutrition Policy and Promotion released 4 another dataset of food prices, national food 5 prices from 2001/2002 linked to that dataset. 6 So by linking those two datasets, you can 7 actually start looking at the relation between 8 food quality, nutrient density of foods, 9 nutrient quality of diets, and their costs. 10 And this is what I want to present to you here 11 today. 12 I believe tomorrow Andrea Carlson 13 and Brian Wansink, who are actually at CNPP 14 developing these very data I will talk about 15 will present before you tomorrow. 16 So we have nutrient composition 17 data, which allows us to calculate energy 18 density and energy cost. And then those same 19 data can be used to calculate not only 20 nutrients per calorie but also nutrients per 21 unit cost. So this actually does open the 22 door to nutrient- and price-related research. (202) 234-4433 Neal R. Gross & Co., Inc. Page 19 1 Now this is a slide which shows 2 you for three food groups, as defined by USDA, 3 the relation between energy density on the 4 vertical axis and energy cost. Now much has 5 been said about energy density of foods. Let 6 me demystify it for you. 7 Energy density of foods is related 8 inversely to the water, water content. Simply 9 put, energy-dense foods are dry. Foods of 10 low-energy density are hydrated. The range 11 goes from water, zero energy density per unit 12 weight to oil, 900 calories per 100 grams with 13 sugar in between. 14 So you have oils, 900 calories per 15 100 grams, spreads and butter, other spreads - 16 - mayonnaise, salad dressings, and so on. And 17 here you have sugars, dry cereals, cooked 18 pasta, and low-energy density but sweetened 19 beverages. Notice on this axis, you have cost 20 per 1,000 calories on algorithmic scale so 21 that each increment equals a tenfold increase 22 in cost. (202) 234-4433 Neal R. Gross & Co., Inc. Page 20 1 So what you have here is oils and 2 sugar providing you with 1,000 calories for 3 approximately 20 cents or less at retail 4 according to the USDA. And more costly 5 desserts and other sweets over here. 6 But notice how this relation shows 7 you the link between energy density and energy 8 costs. When you start putting in other food 9 groups here, notice that you have lower cost 10 beans and eggs and nuts over here, meat in the 11 center, fish and shellfish over here, and 12 dairy products -- lower energy density yogurt 13 and milk and higher energy density cheeses. 14 You go to the next group of foods 15 and here you have vegetables and fruit. 16 Notice that energy density is lowest for salad 17 greens, mostly water. It goes here to fruit, 18 canned fruit in syrup, dried fruit with higher 19 energy density, white potatoes, fried potatoes 20 over here, higher energy density. But notice 21 again the issue of cost per 1,000 calories. 22 So when you put all food groups (202) 234-4433 Neal R. Gross & Co., Inc. Page 21 1 together, you see an inverse relation between 2 energy density and energy cost of foods. You 3 can actually present it in a different way. 4 Rather than energy cost dollars per 1,000 5 calories, you can also show how many calories 6 you can get for a dollar. 7 Suppose you go to a supermarket. 8 You have a dollar in your pocket. What is the 9 food that gives you most calories for your 10 dollar? It is going to be obviously something 11 that contains added sugar and added fat. You 12 know it. I know it. There is a relation here 13 that is an inverse relation. 14 This relationship comes out more 15 strongly in the next few slides. The point I 16 want to make here is that we know about this 17 relationship but we usually talk about foods 18 on the left in terms of the added sugars, the 19 high fructose corn syrup, the high glycemic 20 index, the added fats, the trans fatty acids, 21 the energy density, the minimal nutritional 22 value. (202) 234-4433 Neal R. Gross & Co., Inc. Page 22 1 And in many cases -- not all cases 2 but in many cases -- this is not far from the 3 truth. But we want to bring people over to 4 the right side, towards the fiber, the 5 vitamins, the minerals, the antioxidants, the 6 phytochemicals, all the good stuff. But very 7 often we forget that there is a huge disparity 8 in energy costs in the order of 1,000 percent. 9 So my suggestion is this. First 10 of all, we need to recognize the existence of 11 the cost barrier and somehow include it in our 12 dietary guidelines and recommendations. And 13 then live in the middle. 14 There are many foods here in the 15 center which actually do have high nutrient 16 density and are, in fact, affordable. And 17 foods in the middle include foods from every 18 food group. So, in fact, there are choices to 19 be made within every food group. They do 20 exist. 21 This is actually brought out 22 better on the next slide if you like log/log (202) 234-4433 Neal R. Gross & Co., Inc. Page 23 1 plots. This one shows you a nice linear 2 relation between energy density on the log 3 scale and energy cost, also on the log scale. 4 Notice that yes, there is an overall inverse 5 relationship, which means energy-dense foods 6 on the whole are less expensive. 7 But if you look here in the 8 center, you can see that for any one level of 9 cost, you can go from high energy sweets to 10 low energy vegetables and fruits and dairy 11 products. At the same level of energy 12 density, you can go from less expensive foods 13 to more expensive foods. So there is really 14 plenty of choice within each food group. And 15 there are ways of pointing to and identifying 16 the affordable nutrient-dense foods within 17 each food category and food group. It does 18 not have to be all or nothing. And changing 19 the public's behaviors from over here to over 20 here. 21 A couple more things, all those 22 foods are not necessarily equally frequently (202) 234-4433 Neal R. Gross & Co., Inc. Page 24 1 consumed. They are not all equally 2 acceptable. Some of them need to be cooked. 3 Some of them may require preparation. Some 4 are not part of the mainstream American diet. 5 All of those connections need to be made in 6 order to help people use these foods to create 7 and construct healthy diets. 8 So let me now move from foods to 9 diets because as I said before, some of these 10 foods are used to construct lower cost energy- 11 dense diets. And here what I want to show you 12 are some data from France, which actually 13 illustrate the point that low cost diets are 14 likely to be both energy rich and nutrient 15 poor. 16 What we did here was to take mean 17 French national food prices, attach them to 18 dietary intake data from 2,000 French adults, 19 calculate the cost of the diet at the 20 individual level, and then split the 21 population into equal quartiles. 22 So here we essentially followed (202) 234-4433 Neal R. Gross & Co., Inc. Page 25 1 the same procedures as the epidemiologists do. 2 Just think of the cost of the diet as an 3 index of monetary exposure. This is not what 4 people paid for the diet. This is what the 5 diet intrinsically cost. 6 And once you start doing that, you 7 come across something quite interesting. 8 These are the diets -- let me just go back 9 here -- which cost four-and-a-half Euros per 10 day, five Euros per day, six Euros per day, 11 seven-and-a-half Euros per day. And this is 12 the cost per ten megajoules. 13 We go from lower cost diet -- 14 here's a reference diet -- least cost diet -- 15 to the highest cost diet. The highest cost 16 diets are nutrient rich. They do have lower 17 energy density. And you eat less. So you pay 18 more to eat less or you pay less to eat more. 19 But what you are paying less to eat more of 20 are going to be the added sugars and the added 21 fats. 22 And so the French study was just (202) 234-4433 Neal R. Gross & Co., Inc. Page 26 1 replicated in two studies conducted in the 2 U.S., one in California, one in Seattle. The 3 California study was published last month in 4 the American Journal of Clinical Nutrition. 5 The Seattle study is getting published in a 6 few days in the Journal of the American 7 Dietetic Association. These French data were 8 essentially replicated. 9 The diets over here do have more 10 added fat and added sugar and saturated fat. 11 They are, in fact, cheaper and they are 12 consumed with people by lower education and 13 lower means. 14 But my studies are based on 15 relatively few people -- there are better data 16 that illustrate this issue. Economic 17 pressures drive consumer food choices towards 18 cheaper, more energy dense foods. And let's 19 not forget sweetened beverages. 20 Added sugars and fats do provide 21 more calories per dollar. Lost cost, energy- 22 dense diets naturally lead to overeating and (202) 234-4433 Neal R. Gross & Co., Inc. Page 27 1 weight gain. So paradoxically, spending less 2 may mean eating more. 3 And the Committee has the question 4 about adherence to dietary guidelines. Diet 5 quality is, in fact, measured through 6 adherence of dietary guidelines. 7 The measures of diet quality, we 8 measure diet quality in terms of adherence of 9 dietary guidelines. Think of the healthy 10 eating index. That's what it measures. 11 So here this is our model which 12 was published a while back in a paper co- 13 authored with Steve Specter. We're saying 14 that as food costs go up or if food spending 15 diminishes, consumers or healthy Americans do 16 not want to eat less. They don't want to be 17 hungry. 18 So as a result, what they do is to 19 buy cheaper foods to get you the same number 20 of calories. So that immediately forces them 21 towards more energy-dense foods which provide 22 calories at a lower cost. But it also forces (202) 234-4433 Neal R. Gross & Co., Inc. Page 28 1 them towards less nutrient-rich foods. 2 So in the end, they end up 3 consuming sugars and fats, higher energy- 4 density diets. And actually with higher 5 energy-density diets it is easy to overeat. 6 So rather than eat less, they end up eating 7 more. But those are, in fact, cheaper, empty 8 calories. 9 So the question then becomes what 10 can we do about it and how can we intervene? 11 This is the critical issue. And few people 12 have data showing that lower quality diets are 13 consumed by lower income groups. The best 14 data on this topic actually do not come from 15 my laboratory or from my center. They come 16 from Tom Frieden, the Health Commissioner for 17 the City of New York. 18 The New York City Community Health 19 Survey surveys approximately 10,000 people 20 regarding their diets and health. And so what 21 I have here are data from this study published 22 in the Journal of Urban Health. They studied (202) 234-4433 Neal R. Gross & Co., Inc. Page 29 1 asked about frequent consumption of soda 2 defined as consumption of at least one serving 3 -- 12 ounce serving -- of soda per day. 4 And what we have here is fairly 5 instructive. Notice that consumption -- 6 frequent consumption of soda in New York City 7 was linked to being male, young, minority -- 8 Puerto Rican, Mexican, U.S.-born African 9 American. Consumption of soda was linked to 10 poverty, high poverty, low poverty, to low 11 education, high prevalence of TV watching and 12 yes, it was linked to obesity. 13 But the socioeconomic gradient is, 14 in fact, stupendous. So adjusting for 15 demographics, frequent soda consumption was 16 associated with TV viewing and less physical 17 activity. Adjusting for demographics and 18 behaviors, frequent soda consumption was 19 associated with higher BMI for women but not 20 for men. 21 But what was interesting here is 22 that the demographics of soda consumption, (202) 234-4433 Neal R. Gross & Co., Inc. Page 30 1 demographics of obesity or the location of 2 obesity and those of poverty were, in fact, 3 identical. 4 So now I want to show you 5 something unusual because no one really has 6 data of specific consumption by geographic 7 location. I suspect the industry does that 8 but I have not seen it myself. 9 So here is now prevalence of 10 frequent soda consumption in New York City by 11 New York City boroughs by geographic location. 12 What you see, obviously, is that highest 13 prevalence of frequent soda consumption was in 14 East Harlem, Harlem, Morningside Heights, 15 Brooklyn, and Bedford-Stuyvesant. These are 16 the areas of deprivation and poverty. 17 These were, of course, areas of 18 highest obesity prevalence, as indicated by 19 the same study. Again, you see Harlem, South 20 Bronx, Bedford-Stuyvesant, and parts of 21 Brooklyn and Queens. So you have geographic 22 location of soda consumption, poverty, and (202) 234-4433 Neal R. Gross & Co., Inc. Page 31 1 obesity. 2 And I just have maps of Manhattan 3 showing you poverty distribution of Manhattan 4 in relation to obesity. Take a look at data 5 from an earlier New York City Department of 6 Health and Human Hygiene dataset. 7 What you see here is that the 8 prevalence of obesity quadruples the moment 9 you cross 96th Street. So going from the 10 Upper Eastside, prevalence of obesity at seven 11 percent to East Harlem, obesity prevalence 12 quadruples. 13 There is a direct relation between 14 obesity and poverty, percent of families below 15 poverty and obesity rates over here. And then 16 when you come to diabetes, you see a relation 17 that is even stronger. Diabetes rates 18 increase sevenfold by going from the Upper 19 Eastside to Harlem. 20 And the relation here is extremely 2 21 strong just from Manhattan. R is .87. So as 22 a result, you see a complete continuity (202) 234-4433 Neal R. Gross & Co., Inc. Page 32 1 between consumption of a specific diet, 2 poverty, and obesity. 3 And Manhattan and New York City 4 are not exceptions. I have similar data now 5 for Seattle, where we're now able to plot 6 rates of obesity, diabetes, and metabolic 7 syndrome by census tract. And the social 8 disparities are immense. 9 So let me now move to the logic on 10 how we're thinking about those things because 11 it seems to me that in trying to link specific 12 macronutrients or specific foods to ill health 13 outcomes, to ill health and adverse health 14 outcomes, we are forgetting the important 15 contribution of poverty, social disparities, 16 unemployment, lack of health insurance, under- 17 served neighborhoods. All of those things are 18 part of the picture and part of the package. 19 It actually reminds me some years 20 ago USDA came under attack from Doug Besharov 21 on the pages of Washington Post because he 22 accused the USDA of fattening the poor. You (202) 234-4433 Neal R. Gross & Co., Inc. Page 33 1 may remember that. 2 The argument was kind of strange. 3 The argument was that poor people receive 4 food assistance. Poor people are obese. 5 Therefore, food assistance must have made them 6 obese. 7 Now I, of course, disagree with 8 that but I'm thinking to some extent, we're 9 following similar logic. We're saying okay, 10 poor people do buy energy-dense diets. Yes, 11 they do. They do drink low cost sweetened 12 beverages. Yes, they do. They are obese. 13 Yes, they are. 14 Did a specific macronutrient make 15 them obese? Or was it really something else? 16 And there are two possibilities. The 17 Committee wanted me to address the issue of 18 satiety. One theory is that liquid sugars 19 fail to promote satiety. My theory is more 20 economic and more addressed in the next slide. 21 Take a look at this. This is in 22 the paper that was circulated in the (202) 234-4433 Neal R. Gross & Co., Inc. Page 34 1 epidemiologic reviews. Notice that the foods 2 or the beverages on the top have become in the 3 popular mind associated with obesity. Cola, 4 sweetened drinks, calorics of drinks, and so 5 on. 6 The beverages on the bottom, the 7 100 percent fruit juices, the freshly squeezed 8 fruit juices have been associated with good 9 health. And in some cases, Slimfast -- this 10 is the original Slimfast formula and the 11 current one, they have been associated with 12 weight loss. 13 The eye-opening thing is that the 14 amount of sugar is exactly the same. The 15 price of sugar isn't. The economic access 16 isn't. The amount of sugar is exactly the 17 same. 18 So my thought is to not forget the 19 issues of economics, the price of various 20 foods, the limitations of who buys what foods 21 and beverages and why, and what the 22 combination of those factors has on their (202) 234-4433 Neal R. Gross & Co., Inc. Page 35 1 health. 2 So let me just digress here for a 3 minute to answer specifically the question on 4 satiety because the alternative mechanism 5 suggested by a number of people has been that 6 liquid beverages promote excess calorie intake 7 because they have no satiating power. And the 8 human body is incapable of proceeding liquid 9 calories. 10 So here, all of us who work in 11 this field use the same type of a research 12 design. This is the well-known preload study 13 design. What generally happens is that 14 subjects -- these are experimental studies 15 done in the laboratory -- come into the 16 laboratory, consume a solid or a liquid 17 preload. And then they are given a meal 18 immediately afterwards or maybe two hours 19 later. 20 The size of the meal presented 21 immediately afterwards is a measure of 22 satiation. The size of the meal presented two (202) 234-4433 Neal R. Gross & Co., Inc. Page 36 1 or three hours later is a measure of satiety. 2 In rare cases, subjects go home and record 3 what else they ate during the rest of the day. 4 And if we're looking at satiety, 5 we're also measuring appetitive behavior, in 6 other words hunger and fullness and these are 7 to eat and thirst at 20-minute intervals until 8 the next meal. 9 Now I think it is probably fair to 10 say that the issue is unresolved. Studies 11 conducted by Harry Kissileff at Columbia 12 showed about 20 years ago that soups, liquids, 13 were more satiating than solids. 14 Sometimes I kind of feel those 15 studies were underappreciated and not 16 sufficiently credited at the time. They are 17 classic studies on satiety and how to measure 18 satiety. 19 Then about 15 years later, there 20 came out reports that solids, jelly beans, 21 were more satiating that sugared liquids cola 22 so that complete compensation was observed (202) 234-4433 Neal R. Gross & Co., Inc. Page 37 1 following ingestion of jelly beans and no 2 compensation whatever was observed after 3 drinking soda. 4 Since that time, this same lab, 5 the Dr. Mattes' Lab at Purdue, came out with 6 some other studies on watermelon juice versus 7 solid watermelon, solid apples versus apple 8 juice. And the results were somewhat 9 inconclusive. 10 In some cases there was an effect 11 on intake but no effect on hunger rating. In 12 other cases, there was an effect on hunger 13 rating and no effect on intake. And then the 14 difference between the solids and the liquids 15 was no longer seemingly zero versus 100 16 percent. It was more like six versus 24 17 percent compensation, which is really not the 18 same thing. 19 So I just want to show you very 20 briefly two of our own studies where we 21 compared cola and cookies. The thing to 22 notice here is that calories are exactly the (202) 234-4433 Neal R. Gross & Co., Inc. Page 38 1 same -- 300 calories. Volume is vastly 2 different -- 87 grams, 700 milliliters, mostly 3 sugar. The cookies were fat free so there is 4 no fat. Small amounts of fiber and protein 5 over here but nothing very much. 6 And then we'll look at hunger, 7 satiety, and thirst profiles. And an 8 exceptional finding here, cola did suppress 9 thirst, cookies did not. 10 But this just goes to show that 11 the scales worked. Subjects were correctly 12 recording their thirst. 13 And so it gives us confidence that 14 when we come to fullness and hunger, the same 15 subjects, the same condition, the same scales, 16 are telling us correctly that there was 17 absolutely no difference in satiety between 18 the liquid cola and the solid cookies. Both 19 spoiled appetite if given just before lunch. 20 The next study we did on this 21 topic compared cola, juice, and milk. The 22 advantage here is that all those beverages (202) 234-4433 Neal R. Gross & Co., Inc. Page 39 1 have the same energy density and provide the 2 same number of calories per 100 grams. We 3 usually give a lunch to our subjects. 4 And let me just show you here, the 5 bottom line is there was no difference 6 whatsoever between the three caloric 7 beverages. Soda, juice, and milk, one percent 8 milk, suppressed hunger and promoted fullness 9 to the exact same extent. 10 But, of course, notice that 11 subjects were sensitive to the calories in 12 caloric liquids as opposed to just plain 13 sparkling water with no calories. So the 14 human body's desire to eat is actually 15 sensitive to calories provided in solid or in 16 liquid form. 17 We have now found similar results 18 with liquid yogurts which contain more protein 19 and there may be a higher satiating impact of 20 yogurts. Our subjects are clearly capable of 21 perceiving the calories in yogurt. 22 But -- and this is where more (202) 234-4433 Neal R. Gross & Co., Inc. Page 40 1 research does need to be done -- none of those 2 beverages led to any suppression at lunch. 3 Our subjects came in, ate as they always do. 4 So that at the end of the day, a caloric 5 beverage plus lunch led to more total calories 6 than lunch and plain water. 7 But there was no difference 8 between the different kinds of beverages. And 9 no difference between the cola, the orange 10 juice, and the milk. 11 So let me now move on to this 12 other issue, trying to bring back the 13 economics, the macronutrients, and the food 14 choices together in a kind of cohesive way and 15 in a way that may be useful to you. 16 And here I want to say -- take a 17 step back and say well, if we accept that 18 there is this confound between the consumption 19 of cheap macronutrients, inexpensive 20 macronutrients, added sugar and added fat, 21 poverty, and ill health, will limiting access 22 to those, by itself, automatically lead to (202) 234-4433 Neal R. Gross & Co., Inc. Page 41 1 healthier diets? 2 Or should we take a more direct 3 approach and try instead to identify foods 4 that are nutrient dense, affordable, 5 accessible, and let's not forget appealing? 6 So do we approach things by removing and 7 limiting? Or do we approach our task by 8 pointing to appropriate options? 9 And so here I have some recent 10 data which is about to be submitted for 11 publication from Victor Fulgoni, my colleague 12 who has been working on looking at the quality 13 of diet of participants in the National Health 14 and Nutrition Examination Survey from two 15 standpoints. 16 What we did here was to create an 17 avoidance index based on the diet content of 18 added fat -- no, of added sugar, saturated 19 fat, and sodium. We called it an index or a 20 score based on nutrients to limit. And then 21 we used the nutrient density approach which 22 was more mixed. We're using nutrients to (202) 234-4433 Neal R. Gross & Co., Inc. Page 42 1 encourage and nutrients to limit, both. 2 So what I want to show you here is 3 the type of diets that -- I want to show you 4 how the two types of scores discriminate 5 between the quality of the diets of 6 participants in the NHANES study. 7 We calculated mean scores for each 8 person and the participants were split into 9 five equal groups based on their scores. So 10 here let me just take you through the first 11 slide. 12 This score is based on avoidance. 13 It does have the added sugar and the 14 saturated fat and sodium. 15 So the bottom quintile, these are 16 the people who had least added sugar, least 17 saturated fat, and least sodium in their diet. 18 And these are people who have the most. And 19 this is the score based on nutrient density of 20 foods, which includes nutrients to encourage 21 and nutrients to limit. 22 So a score which is low in sugar, (202) 234-4433 Neal R. Gross & Co., Inc. Page 43 1 low in saturated fat, is higher in vitamin C 2 intakes but not by much, which means that 3 limiting problematic nutrients does not, by 4 default, necessarily lead to healthier diets. 5 On the other hand, the other 6 approach does reliably discriminate between 7 diets which are low in vitamin C and those 8 that are high in vitamin C. 9 And here we have the same picture 10 for vitamin A. Again, better discrimination 11 in terms of diet quality and adherence to 12 dietary guidelines. We see the same thing for 13 calcium intakes, the better step-wise 14 approach, again reflecting better compliance 15 with dietary guidelines and higher diet 16 quality. 17 The same thing appears for food 18 groups. Notice again that diets which are 19 lowest in saturated fat and lowest in added 20 sugar are not necessarily that much higher in 21 vegetables. This score does a better job. 22 And then here we have fruit (202) 234-4433 Neal R. Gross & Co., Inc. Page 44 1 consumption. Those scores do a nice job. And 2 what's interesting here, moving past no 3 consumption is that the total energy 4 consumption is actually lower for the most 5 nutrient-dense diets. 6 So this is interesting because 7 that confirms the French data and it also 8 confirms the data from Seattle and from 9 California. The more nutrient dense a diet is 10 actually the less you eat. 11 So let me just kind of start 12 wrapping here. Going here from energy density 13 to nutrient density, we can focus our dietary 14 guidelines and dietary advice on nutrient- 15 dense foods. 16 Nutrient density provides a better 17 approximation of diet quality and extra 18 calories that people consume than, in fact, 19 scores or indices or advice based on saturated 20 fat, sugar, and salt. The avoidance approach 21 has been telling people what not to eat. 22 What I'm suggesting is that we (202) 234-4433 Neal R. Gross & Co., Inc. Page 45 1 rephrase our approach and actually focus on 2 constructing affordable, healthier diets. We 3 cannot assume that limiting access to any one 4 nutrient, complicated as it is by incomes, 5 cost, poverty, and so on, will result in 6 healthier diets. 7 What we need to do is to show the 8 public the way to identify affordable, 9 accessible, nutrient-rich foods. So, yes, 10 going back to my initial fundamental question, 11 yes, it is possible to improve diet quality 12 while maintaining or reducing diet costs but 13 only if we help the public identify 14 affordable, accessible, appealing foods within 15 each food group. And also tell them what to 16 do with it. 17 I cannot overemphasize the 18 importance of nutrition education and cooking 19 skills. To some extent, it does come down to 20 access, money, knowledge, and time. 21 And limiting low-cost foods may 22 not necessarily give us the answer that we (202) 234-4433 Neal R. Gross & Co., Inc. Page 46 1 seek. Rather promoting affordable choices is 2 where we want to go. 3 So thank you for your attention. 4 I'll be very happy to answer the Committee's 5 questions. 6 CHAIR VAN HORN: Thank you very 7 much for that excellent presentation. Thank 8 you very much. This is Linda Van Horn 9 speaking. 10 We have about ten minutes. If it 11 is all right, we'll just open the floor to 12 questions from the Committee members. 13 Mim, you look like you have a 14 question. 15 MEMBER NELSON: This is Mim 16 Nelson. Thanks, Adam, very much. 17 I guess two questions. First is 18 I'm thinking of, you know, your graph with the 19 cost per 1,000 calories. And that, you know, 20 green leafy vegetables get a really bad score 21 there. 22 But is that the -- I'm not (202) 234-4433 Neal R. Gross & Co., Inc. Page 47 1 questioning -- I think that -- I completely 2 buy into your argument. But when we think of 3 something like green, leafy vegetables, we may 4 not want to be eating a thousand calories of 5 them. That we're only going to get 100 6 calories of them or 50. That, you know, the 7 cost of the 50 calories of a green, leafy 8 vegetable is actually not that -- maybe that 9 expensive. 10 So is that something that should 11 enter -- 12 DR. DREWNOWSKI: Yes. 13 MEMBER NELSON: -- that's sort of 14 the first -- 15 DR. DREWNOWSKI: Of course. You 16 are a step ahead of me because we're now 17 joining the nutrient composition data and the 18 food price data to actual diets of 19 participants in the National Health and 20 Nutrition Examination Survey. 21 MEMBER NELSON: And then you can 22 look more at that. (202) 234-4433 Neal R. Gross & Co., Inc. Page 48 1 DR. DREWNOWSKI: Then we can look 2 at -- 3 MEMBER NELSON: Got it. Right. 4 DR. DREWNOWSKI: Exactly. The 5 diets with higher consumption of different 6 types of vegetables and fruit and look 7 specifically at their costs. 8 MEMBER NELSON: Right. 9 DR. DREWNOWSKI: We're in the 10 process of doing that. And I believe USDA is 11 also in the process of joining those two 12 datasets together for similar type research. 13 MEMBER NELSON: Okay. So -- 14 thanks, that's great. 15 The next one is more a sort of -- 16 I don't know -- we've been talking a lot in 17 our committee about the effect of the 18 environment in its fullest sort of range. 19 And thinking about the data in New 20 York that you presented and with sodas -- and 21 I'm not saying I'm an advocate of sodas 22 necessarily but is it -- how -- if there are (202) 234-4433 Neal R. Gross & Co., Inc. Page 49 1 so many factors that go into what foods are in 2 those environments that are beyond sort of the 3 personal choice of, you know, I want a soda 4 versus I want something else. 5 And so how influential is poverty 6 or low income versus literally, you know, the 7 schools are different in that part because, 8 you know, the parents have advocated to get 9 the soda machines out of the other schools. 10 So availability becomes an issue. 11 And so is it that simplistic to 12 think of it from an economic point of view 13 versus there are so many other factors of what 14 foods are in those neighborhoods? 15 DR. DREWNOWSKI: That's an 16 excellent question. It's not simplistic at 17 all. It is very, very complex. 18 Environment has much to do with it 19 for a number of reasons from the purchasing 20 power of the neighborhood to the type of foods 21 which are stocked in a given neighborhood, to 22 access and transportation, to the quality of (202) 234-4433 Neal R. Gross & Co., Inc. Page 50 1 schools, and so on. 2 And this is for this reason that 3 our Center for Public Health and Nutrition in 4 Seattle is very closely working with urban 5 planners, urban designers, economists, 6 transportation specialists who have taken 7 things out of nutrition and epidemiology, 8 really moving into public health and policy. 9 But what you are really 10 fundamentally saying is that these choices are 11 beyond any individual control. 12 MEMBER NELSON: Right. It's not 13 about personal choice. 14 DR. DREWNOWSKI: It's not about 15 personal choice. 16 MEMBER NELSON: Right. 17 DR. DREWNOWSKI: We're completely 18 together on that. And I would actually go 19 further and say to some extent, some segments 20 of our society actually have no choice or very 21 limited choice. And what can we do to make 22 sure that they do, indeed, have access to -- (202) 234-4433 Neal R. Gross & Co., Inc. Page 51 1 MEMBER NELSON: Right. 2 DR. DREWNOWSKI: -- nutrient-rich 3 foods. How can we do that? Because merely 4 suggesting‘‘have leafy greens’’ may not do it. 5 MEMBER NELSON: Right. 6 DR. DREWNOWSKI: We need to be 7 much more subtle and nuanced about that and 8 say this is the way really to go step by step, 9 taking into account preferences, culture, 10 access, cost, transportation. All of those 11 things are hugely important. 12 MEMBER NELSON: So it may be that 13 the cost issue is more related to just the 14 fact that they live in those environments 15 versus that they have limited income 16 themselves? I mean if they had limited income 17 and they lived down, you know, in the 50s 18 midtown, maybe the -- if they, for some -- 19 DR. DREWNOWSKI: Did you say that 20 people with limited incomes who live on Park 21 Avenue -- 22 MEMBER NELSON: No, but I'm just (202) 234-4433 Neal R. Gross & Co., Inc. Page 52 1 saying that -- I mean I'm using a hypothetical 2 example but if that person with limited income 3 actually lived in a different neighborhood, 4 their food intake might be quite different. 5 DR. DREWNOWSKI: They would have 6 access to better foods, which -- 7 MEMBER NELSON: Yes. 8 DR. DREWNOWSKI: -- means they 9 would have physical access in -- 10 MEMBER NELSON: Yes. 11 DR. DREWNOWSKI: -- terms of 12 proximity. What we're doing right now in 13 Seattle is trying to distinguish between 14 physical access and economic access -- 15 MEMBER NELSON: Yes. 16 DR. DREWNOWSKI: -- because you 17 may be living next door to Whole Foods -- 18 MEMBER NELSON: Right. 19 DR. DREWNOWSKI: -- or to another 20 -- 21 MEMBER NELSON: Yes. 22 DR. DREWNOWSKI: -- excellent (202) 234-4433 Neal R. Gross & Co., Inc. Page 53 1 store but it doesn't really help you if you 2 can't afford to walk through the door. And 3 many people can, some people cannot. Again, 4 what to do. 5 So it is a question of 6 differential access. I agree with that. I 7 think it is an issue for agricultural 8 economists and the issue of what food supply 9 system -- 10 MEMBER NELSON: Yes. 11 DR. DREWNOWSKI: -- to assure 12 access to healthy foods. 13 MEMBER NELSON: Right. 14 DR. DREWNOWSKI: I think it is a 15 very important issue. 16 CHAIR VAN HORN: Thank you. 17 I think Larry has a question. And 18 then Eric. 19 MEMBER APPEL: Yes, this is Larry 20 Appel. Great presentation. 21 I want to follow up on that access 22 issue. Janet King, who led the Committee five (202) 234-4433 Neal R. Gross & Co., Inc. Page 54 1 years ago, commented that, you know, they set 2 up, you know, farmers markets in Berkeley, you 3 know. And so there was access. But there was 4 very limited uptake. 5 I live or I work across the street 6 from a market that has the best food in the 7 world as well as the worst food in the world 8 and so there is access. But I see very stark 9 differentials. 10 So I'd like to have you comment 11 more about this access issue because I 12 actually think that that might be perhaps 13 overblown as a solution to this problem. 14 DR. DREWNOWSKI: Now thank you for 15 the question. My specific bias here is that I 16 believe in assuring economic access. I think 17 we've all talked about physical access and 18 proximity. Physical proximity to either fast 19 foods or supermarkets will determine your 20 health. 21 I really don't think so. I really 22 think that economic access and being able to (202) 234-4433 Neal R. Gross & Co., Inc. Page 55 1 walk through the door really is what matters. 2 I really do think that in Seattle, for 3 example, we do not have food deserts. And 4 there are supermarkets serving both low income 5 groups and upper income groups. 6 And they buy different foods just 7 like you say, because they have access to 8 different -- it is a differential economic 9 access. 10 But let me again emphasize the 11 notion of knowledge, money, and time. My 12 belief is that you can eat well if you have 13 some combination of knowledge, money, and 14 time. 15 If you have knowledge and time, 16 you can do with less money. So nutrition 17 education and cooking skills will get you by. 18 If you have time and money, you have no 19 problem. 20 But a number of people in our 21 society are zero for three. And that's a 22 problem. What can we do? And how can we then (202) 234-4433 Neal R. Gross & Co., Inc. Page 56 1 make sure that they do not fall outside of our 2 recommendations and guidelines. We want to 3 include everybody. How do we do that? 4 So knowledge, money, and time. 5 And dietary guidelines do provide the 6 knowledge, the information. They don't 7 provide the money. But that can be taken care 8 of through other ways. 9 CHAIR VAN HORN: Eric, did you 10 have a question? 11 MEMBER RIMM: Yes, this is Eric 12 Rimm. 13 I was going to add something very 14 similar to Larry because I thought I had heard 15 anecdotally or seen pilot studies where they 16 tried to make fruits and vegetables 17 essentially free through a food stamp program. 18 DR. DREWNOWSKI: Yes. 19 MEMBER RIMM: And people still 20 didn't access them. And it's sort of what 21 Larry is saying. And I guess it ties into 22 what I thought you were implying initially is (202) 234-4433 Neal R. Gross & Co., Inc. Page 57 1 that people buy soda because they need cheap 2 calories. Or soda was your example. But I 3 think it may be a lot more than that. 4 I mean you started to say that. 5 But I'm hoping we don't walk away from here 6 saying the only reason people buy soda is 7 because they have to and they need cheap 8 calories. It seems like it is much -- 9 DR. DREWNOWSKI: Well -- 10 MEMBER RIMM: -- much more 11 complicated than that. 12 DR. DREWNOWSKI: Of course. 13 MEMBER RIMM: And if you give 14 people free spinach and you give people -- 15 even if you may teach them how to use it or 16 give them food stamps or access to it, that 17 there still is a differentiation of what 18 people desire based on culture or based on 19 access to television, based on all sorts of 20 other cultural exposures. 21 DR. DREWNOWSKI: There are, of 22 course, issues of food preference and taste. (202) 234-4433 Neal R. Gross & Co., Inc. Page 58 1 And let's face it, some of the energy-dense 2 foods do taste good. I can't deny that. Yes, 3 they do. 4 And I want to say that the USDA 5 pilot program for schools providing free 6 vegetables and fruit was actually, by all 7 accounts, a great success at least in the 8 state of Washington. 9 And now the new WIC program is 10 allowing certain amount of fresh vegetables 11 and fruit as part of the WIC package. And 12 we'll see what success that has. So yes, 13 there are programs. And I wouldn't be 14 pessimistic. They do have some degree of 15 success. 16 But in some cases, it really is 17 the knowledge and cooking skills. People get 18 their kale but they don't necessarily know 19 what to do with it. And other foods become 20 cheaper, tastier, more available. 21 MEMBER RIMM: Are those data 22 published yet? The success of some of those (202) 234-4433 Neal R. Gross & Co., Inc. Page 59 1 programs? 2 DR. DREWNOWSKI: I have not seen 3 those. I have seen one report from USDA about 4 this topic. I think it is time to publish 5 those. The evaluations are very important. 6 MEMBER RIMM: I think that would 7 be very important. 8 CHAIR VAN HORN: Thank you so 9 much. 10 We're going to need to move on to 11 our next speaker. 12 DR. DREWNOWSKI: Thank you. 13 CHAIR VAN HORN: But that was an 14 excellent presentation. And so that we don't 15 burst the eardrums of people listening in, we 16 will not applaud. But please accept our 17 gratitude. 18 It's my pleasure to introduce our 19 next speaker, Dr. Frank Sacks. Dr. Sacks is 20 Professor or Cardiovascular Disease Prevention 21 in the Department of Nutrition at Harvard 22 School of Public Health. (202) 234-4433 Neal R. Gross & Co., Inc. Page 60 1 He is a Senior Attending Physician 2 at Brigham and Women's Hospital and Professor 3 of Medicine at Harvard Medical School. 4 Dr. Sacks is involved in research 5 and public policy in nutrition, cholesterol 6 disorders, hypertension, and cardiovascular 7 disease. 8 He is the Chair of two NHLBI- 9 sponsored trials, the POUNDS LOST trial that 10 we'll hear about today and the OmniCarb Trial. 11 He is a member of the new NHLBI 12 Clinical Guidelines for Cardiovascular Risk 13 Reduction first expert panel. 14 And it is my pleasure to introduce 15 Dr. Frank Sacks who will tell us more about 16 POUNDS LOST. 17 DR. SACKS: Okay. Thank you, 18 Linda. 19 I appreciate the opportunity to be 20 here. And to share with you some new findings 21 on dietary macronutrients and weight loss, and 22 to just cover some previous trials, an (202) 234-4433 Neal R. Gross & Co., Inc. Page 61 1 overview of the state of the macronutrients 2 weight loss topic, discuss the behavioral 3 components of success in weight loss. 4 And then I was asked, at the end 5 to discuss the issue of sodium and 6 particularly the dose effect of sodium on 7 blood pressure and issues relating to what the 8 appropriate target would be for sodium intake. 9 So I am going to go through some 10 of these slides very fast. So I guess I'm 11 told that we have an absolute limit on time. 12 So excuse me for some of that. 13 All right. So first I'm going to 14 discuss low-fat diets, the background to that. 15 Now the longtime paradigm is that low fat, 16 high carbohydrate diets will promote weight 17 loss or prevent weight gain for a variety of 18 metabolic reasons. 19 Now that paradigm has been called 20 into question but I do think there is some 21 validity to it. For example, vegetarians eat 22 low fat but lots of -- but the carbohydrate( 202) 234-4433 Neal R. Gross & Co., Inc. Page 62 1 rich foods are full of vegetables, whole 2 grains, and so forth. 3 And they are much -- they lose 4 weight. And there is no question this kind of 5 diet can promote weight loss even if you 6 aren't even trying to lose weight because this 7 population was not trying to lose weight. 8 They just lost weight. And so that paradigm 9 can work in certain, you know, with a certain 10 type of high carbohydrate, low fat diet. 11 The same sort of thing in coronary 12 patients in San Francisco, remarkable 13 sustained weight loss, 22-pound difference 14 against the control group. Again, very low 15 fat, high carbohydrate vegetarian diet full of 16 foods that I suppose are very nutrient-rich 17 but also very rich in fiber. 18 And the carbohydrate is low 19 glycemic index for a lot of the carbohydrate- 20 rich foods. So in certain selected 21 populations, I think this paradigm works very 22 well. (202) 234-4433 Neal R. Gross & Co., Inc. Page 63 1 Now in the larger population or 2 when you just select from the general 3 population, it doesn't necessarily work so 4 well. So here is also a strict vegetarian, 5 vegan study, by Neal Bernand in that group. 6 And they randomized patients to a 7 vegan group or a standard low fat group for 8 weight loss, gave some of them support, a lot 9 of sustained support and contact, encouraged 10 them to be on the diet, and the vegan group 11 lost a little more weight than the standard 12 low fat group did, but only if they were given 13 sustained support. 14 So I just want to make that point 15 that certainly in these researchers' hands, 16 the vegan group did a bit better than the 17 standard low fat group. However, the second 18 dimension of these results are that without 19 any support, neither group did well at all. 20 So that support is extremely important. 21 So now let's move to the opposite 22 type of diet, a low carbohydrate diet. And (202) 234-4433 Neal R. Gross & Co., Inc. Page 64 1 we've had a lot of different studies. And you 2 can see a pattern where in the first few 3 months, the low carb -- Atkins -- this is an 4 Atkins diet, the low carb Atkins diet promotes 5 weight loss but then that weight is regained 6 faster than a conventional low fat diet. And 7 at the end, there was no significant 8 difference at the 12-month point. 9 Okay, another study, similar, 10 rapid weight gain of the Atkins diet, regain 11 from six to 12 months such that at the end, 12 there was no difference in weight loss between 13 the Atkins and the conventional diet. 14 In fact, if you carry out those 15 trajectories, you would imagine that in 16 another few months there would be really no 17 difference between groups. And they might 18 even cross over and give an opposite result. 19 So very important to continue 20 these studies until we can get some sense of 21 the long-term results. 22 Now here, comparison of four (202) 234-4433 Neal R. Gross & Co., Inc. Page 65 1 diets. The Atkins diet is the bottom line 2 compared to three other types of diets, 3 including its opposite diet, the Ornish high 4 carbohydrate, low fat diet. Again, as you 5 see, there's rapid weight loss in the Atkins 6 diet. More regain. 7 And at the end of that study, 8 there was no significant difference, according 9 to the author's original protocol, between 10 these different diets. 11 Okay, so now how about yet another 12 type of diet, a Mediterranean high fat diet. 13 All right. This is a study that I did with 14 Kathy McManus. And wanted to see whether 15 people could lose weight on a high fat 16 Mediterranean-style diet. And indeed they 17 did. 18 Compared to a low fat diet, weight 19 loss was the same at six months. Pretty much 20 the same at 12 months. But at 18 months, the 21 Mediterranean group sustained the weight loss 22 whereas the other group regained a lot of the (202) 234-4433 Neal R. Gross & Co., Inc. Page 66 1 weight. 2 Now also adherence at 18 months 3 was much better and participation was much 4 better in the Mediterranean group. And here's 5 a result that other weight loss trials have 6 found that it is good to stay in these 7 programs. 8 The drop outs, regardless of 9 whether they were on low fat or Mediterranean, 10 had a gain of nine pounds over 18 months. 11 Those staying in the program, regardless of 12 whether it was low fat or Mediterranean, lost 13 11 pounds. So, again, participation seems to 14 be very, very important in these studies. 15 Very recently yet another study 16 compared three diets. The lower curve here is 17 the Atkins diet. And, again, just like the 18 previous studies, you see rapid weight gain at 19 about six months. But then rapid regain. 20 So that at the end of the study, 21 at two years, you see an absolutely similar 22 weight loss in two very different diets, the (202) 234-4433 Neal R. Gross & Co., Inc. Page 67 1 Atkins diet and the Mediterranean diet, 2 somewhat superior to a low fat diet. There 3 were more dropouts in the Atkins diet so that 4 is an interesting result. 5 Okay, so how do we interpret this 6 big collection of findings? Well, one, the 7 certainly divergent results that each diet 8 type in the hands of some investigators showed 9 the superiority of other types. 10 There is no obvious pattern of 11 results across this collection of studies. 12 And with the Atkins diet, superiority in the 13 first few months was often not sustained by 14 one to two years. In fact, in no study was 15 there truly a statistically significant 16 difference between Atkins and the comparator 17 studies that went out to a year. 18 All right. So what were some 19 limitations in some of these studies? Here is 20 a whole host of limitations that were 21 discussed and written about by colleagues. 22 But I'll say I think what is very important to (202) 234-4433 Neal R. Gross & Co., Inc. Page 68 1 say I think lack of information on adherence 2 is one of the most important problems in some 3 of these studies. If you don't know what 4 their participants were eating, you really 5 don't know if the recommended diet did 6 anything. Or whether it was some other aspect 7 of the program. 8 A large percentage of dropouts, 9 some had 50 percent dropouts. So it's no 10 longer a valid randomized trial if you lose 11 half the participants. It becomes something 12 else, some other kind of research design like 13 observational. 14 And, very important: novelty of 15 one of the diets, media attention. It is 16 marketing. There are certain biases that can 17 enter into a trial that may not be so well 18 intended and may not be perceived. And I've 19 had that happen with a study I did on the 20 Mediterranean diet some time ago. There were 21 subtle biases that fit in so that I do think 22 that regardless of a researcher's good (202) 234-4433 Neal R. Gross & Co., Inc. Page 69 1 intentions, sometimes equipoise is not 2 achieved in weight loss trials. And sometimes 3 that leads to a result that's, you know, in 4 line with the researchers' hypotheses, but it 5 may not be a generalized result. 6 All of these considerations lead 7 us to propose to the National Heart, Lung, and 8 Blood Institution a trial that we call the 9 POUNDS LOST trial. And that was done at 10 Harvard and also done at Pennington. And 11 George Bray was my partner in doing this study 12 along with a very, very terrific group of 13 researchers at both institutions. 14 So we randomized 811 people to 15 four diets. So I'd like to describe this 16 trial in some detail and give you a sense of, 17 I think, where we're at with the macronutrient 18 hypothesis and what future directions might 19 be. 20 So two of these diets were low in 21 fat, 20 percent, and two of the diets were 22 high in fat, 40 percent. So there were 400 (202) 234-4433 Neal R. Gross & Co., Inc. Page 70 1 people in low fat and 400 in high fat. 2 Now within those categories of 3 fat, half of them were taught a diet that is 4 15 percent protein. Half of them, 25 percent 5 protein. And then if you look at the 6 carbohydrate content, embedded in this design 7 is a dose response study of carbohydrates from 8 65 percent down to 35 percent of calories. 9 Now in designing these diets, we 10 designed them with similar foods but in 11 different proportions. And no diet was a 12 control diet. No diet was considered a bad 13 diet. All diets were done -- were composed 14 with healthful guidelines such as those of the 15 American Heart Association's guidelines. 16 So if we look at the comparisons 17 then, this is a factorial study, about 400 per 18 group, dietary fat level, 20 versus 40, 19 dietary protein 15 versus 25. Carbohydrate, 20 65 down to 35 with a linear dose effect 21 hypothesized. 22 All right. Now I'd like to (202) 234-4433 Neal R. Gross & Co., Inc. Page 71 1 describe in some detail what the program is 2 for weight loss -- the macronutrient targets 3 with a paramount teaching objective. We 4 wanted participants to hit the macronutrient 5 targets. 6 So we specified menus for two week 7 cycles for each group. They knew they were 8 going to do this. We showed them examples 9 coming in. 10 We gave them motivational, 11 psychological questionnaires, and so forth -- 12 really wanted people who were fully informed 13 about what they were getting into, knew what 14 it was about, and were motivated. And we had 15 behavioral psychologists like Don Williamson 16 devise that. 17 Participants were taught to follow 18 meal plans exactly. Energy reduction bills 19 750 kilocals, doubly-labeled water showed that 20 it was about 300 to 400 calorie reduction 21 achieved at six months. 22 Okay, physical activity goal, 90 (202) 234-4433 Neal R. Gross & Co., Inc. Page 72 1 minutes per week, same technique and intensity 2 was used in all groups. And this is what we 3 did -- a lot -- to keep these people in. 4 We had group sessions three out of 5 every four weeks for six months then two out 6 of four weeks for the remainder. Individual 7 counseling sessions every eight weeks for two 8 years. The Pennington people devised a web- 9 based system for participants to record diet 10 and exercise and obtain rapid feedback daily 11 about whether they reached their macronutrient 12 or calorie goals. 13 Contact among the groups were 14 avoided. And it is very important to say that 15 the investigators taught the staff and the 16 staff taught the participants that each diet 17 had an equal chance of success in line with 18 divergent results of previous studies that I 19 have summarized. And the goal was trial-wide 20 equipoise. 21 And I think we did achieve that in 22 a sense. The investigators had different (202) 234-4433 Neal R. Gross & Co., Inc. Page 73 1 opinions about which diet would work best. 2 And we really were committed to this concept 3 of equipoise. 4 The baseline characteristics then 5 of the study, 800 were randomized, 645 6 completed the study; that is, provided a body 7 weight at the end, 80 percent. And that's 8 truly the best we could do. 9 It is very difficult to bring 10 patients back for weight measurements when 11 they were unhappy with their weight loss. 12 That's basically the reason. It's a very 13 different kind of study than other kinds of 14 nutritional studies. 15 We had 64 percent women and 27 16 were in the overweight category, 73 percent in 17 the obese category. 18 Okay, so here was the primary 19 trial outcomes. So pre-specified primary 20 outcome, change in weight from time zero to 21 two years, all randomized participants, the 20 22 percent that did not come in for a body weight (202) 234-4433 Neal R. Gross & Co., Inc. Page 74 1 measurement, we imputed their data using Tom 2 Wadden's approach. 3 So, this is it. There's two 4 years. Absolutely no difference based on 5 protein, fat, or carbohydrate. 6 Now the completers, the 80 7 percent, showed the same type of result. The 8 average weight loss was about four kilograms 9 at two years across all of the groups and diet 10 comparisons. 11 Okay, now this graph shows the 12 six, 12, 18, and 24 month results for each of 13 the four dietary types. So you can see, for 14 example, at the six-month point, you see four 15 symbols. And these represent the four diets. 16 You really don't need to know 17 which is which because it is quite obvious 18 that there's absolutely no difference in 19 weight loss. The average weight loss is about 20 six kilograms at six months. 21 The adherence was very good at six 22 months. There were 93 percent that came back (202) 234-4433 Neal R. Gross & Co., Inc. Page 75 1 for measurements at six months. So we feel 2 this is a very solid result for a six-month 3 time point. 4 And then there was -- that was 5 sustained to 12 months, so we didn't see any 6 regain from six to 12 months like other 7 studies generally did, I think because we had 8 a sustained program. But then they had some 9 regain from 12 to 24 months similar in all the 10 groups. 11 These are the same data for 12 completers. Again, very clearly at six months 13 no difference, and no significant differences 14 here whatsoever. 15 Now waist circumference, we know 16 where fat is is a relevant factor for 17 metabolic abnormalities. So waist 18 circumference was our secondary outcome. You 19 can see weight loss -- I mean loss of waist 20 circumference at six months, absolutely 21 identical across all four groups. 22 Reduction in waist line continued (202) 234-4433 Neal R. Gross & Co., Inc. Page 76 1 to 12 months, no difference among groups. And 2 there was a small amount of regain of waist 3 circumference -- less that regain of total 4 body weight. 5 We've done some body composition 6 analyses. It looks like abdominal fat did not 7 return quite as much as fat in other 8 locations. That's very interesting. We'll 9 have a report on that sometime in the future. 10 Now cut points for weight loss, 11 whether it is a five percent weight loss or a 12 ten percent or greater or 20 kilograms or 13 greater, you can see there is really no 14 difference at all across any of these groups. 15 Very interestingly, even though on 16 average most patients gained weight after six 17 months or after a year, about a quarter of the 18 participants continued to lose weight after 19 six months. 20 That was a very successful group - 21 - lost 9.3 kilograms with no difference across 22 the diets. So there are people who will (202) 234-4433 Neal R. Gross & Co., Inc. Page 77 1 continue to lose weight and get a very, very 2 good result at two years. We shouldn't give 3 up in that regard. 4 There are a number of theories and 5 evidence about different macronutrients and 6 satiety and satisfaction and food craving and 7 whatnot and our behavioral psychologists at 8 Pennington are experts in this, they included 9 a number of standard questionnaires in this 10 study relating to food craving and dietary 11 restraint and so forth. 12 There were absolutely no 13 differences by diet group at six months or at 14 24 months, to their great surprise. You know 15 whatever that data early on about satiety, 16 very good experiments, they just didn't seem 17 to carry through in this study to the six 18 month point or to the two year point. 19 Now just speaking about adherence, 20 the Danziger study compared these four diets 21 from Atkins out to Ornish and this is self- 22 reported adherence levels. And you see they (202) 234-4433 Neal R. Gross & Co., Inc. Page 78 1 started fairly high but by six months, self- 2 reported adherence decreased dramatically. 3 And it was the same in all four of 4 the groups -- no particular diet type promoted 5 adherence in this particular population-based 6 study. And that's what we found in our own 7 study as well. 8 This is what really did have a -- 9 seemed to have a lot to do with the weight 10 loss result and that's group session 11 attendance. And here on the X axis, we have 12 number of sessions attended, and the Y axis, 13 weight change in kilograms at two years. And 14 you can see participants, on average, lost 0.2 15 kilograms per session attended over two years. 16 That's the -- and -- but you 17 notice that there is a huge difference across 18 -- there's a huge difference among people. We 19 had people who attended sessions and lost 30 20 kilograms. We had patients who attended most 21 of the sessions and actually gained a few 22 kilograms. (202) 234-4433 Neal R. Gross & Co., Inc. Page 79 1 Then we had patients who came to 2 the first couple of sessions and then left. 3 And never came back except at two years. Most 4 of those patients didn't do so well. But a 5 few of them did extremely well. Just didn't 6 need us. So I'm very interested in these 7 kinds of individual variables -- differences 8 in participation and weight loss. 9 Now what I just described to you 10 for the total group is exactly the same in all 11 four of the diet groups. Other studies have 12 showed that sustained interaction with 13 something -- with the research team had a lot 14 to do with weight loss. 15 This looked at Weight Watchers. 16 It's certainly better than two dietitian 17 consultations to have a sustained program. 18 Internet behavioral e-counseling also is 19 successful. The Premier study follow-up 20 shows, again, it was very important to have 21 sustained interaction. 22 Now I'd like to mention adherence (202) 234-4433 Neal R. Gross & Co., Inc. Page 80 1 to the macronutrient goals because we found 2 that over time, patients that are participants 3 tended to converge on their pre -- their pre- 4 study macronutrient goals or macronutrient 5 intakes. 6 For example, the low fat diet that 7 had its target of 65 percent -- and that's 8 what participants did very early on -- but by 9 six months, their carb intake decreased closer 10 to what they usually ate. And the low carb, 11 35 percent, increased as well. Kind of they 12 converged toward what their population average 13 is. And by two years, convergence on it 14 occurred further. 15 So it seems to me that ambitious 16 macronutrient goals in a population-based 17 study are not achievable even though weight 18 loss is achievable. And they will -- 19 participants will gravitate to their usual 20 intake over time. 21 Even at two years, there was a 22 difference here. And this is not unique to (202) 234-4433 Neal R. Gross & Co., Inc. Page 81 1 our study. In all previous studies, this kind 2 of phenomenon has been found. 3 Okay, finally with regard to the 4 study, there were some dietary differences on 5 risk factors. For example, the low fat diets 6 had -- their LDL levels went down more -- not 7 that much -- six percent compared to one 8 percent in the higher fat group. 9 But in the higher carb, low fat 10 groups, insulin did not go down as much, HDL 11 did not go up as much. So if you look at this 12 total risk factor picture, you'd say well, 13 maybe it is a tie between everything. But in 14 people who have dyslipidemia, may have some 15 insulin resistance, perhaps the highest carb 16 diet is not the best choice even though it did 17 just as well for weight loss. 18 So in summary then, reduced 19 calorie diets achieve similar weight loss 20 after two years regardless of macronutrient 21 emphasis, that satisfaction, satiety, and 22 cravings were similar, average weight loss (202) 234-4433 Neal R. Gross & Co., Inc. Page 82 1 nine pounds by intention to treat, and two 2 inches of waist circumference. And overall, 3 all groups had favorable changes in risk 4 factors. 5 So how do we translate the 6 findings? Well, successful diets for weight 7 loss can emphasize a large range of 8 macronutrient intakes. And these diets are 9 made with foods that reduce risk of 10 cardiovascular disease. Risk factors 11 improved. Low fat may not be the best for 12 metabolic syndrome or diabetes. 13 Ongoing counseling sessions, very 14 important to achieve and maintain weight loss 15 no matter what group they are in and that 16 successful diets for weight loss, I think, can 17 be tailored to individual patient's personal 18 and cultural preferences to achieve long-term 19 success. 20 And maybe that's really the key to 21 go after in the future rather than pushing 22 people to eat a particular amount of carb or (202) 234-4433 Neal R. Gross & Co., Inc. Page 83 1 protein or whatnot. 2 So, thank you for that, for paying 3 attention to that. And now I'm going to 4 briefly go over some aspects of the sodium 5 hypertension thing from mostly data from the 6 DASH sodium study. 7 Okay, so prior to DASH sodium, 8 McGregor did a double blind sodium study. 9 It's a beautiful study in moderate 10 hypertensives. And what he showed is that 11 going from 200 millimoles to 100 millimoles 12 reduced blood pressure the same as going from 13 100 to 50. And that really suggested a lot of 14 linear effect or an intensification on a 15 linear scale of the sodium-blood pressure 16 relation. 17 So in the DASH sodium study, we 18 wanted to do this on a much larger scale, more 19 population applicable. We then looked at 150 20 millimole to 100 to 50 or 3.5 of sodium, 2.3 21 grams or 1.2 grams of sodium. So those were 22 the ranges that we tested in 412 people. (202) 234-4433 Neal R. Gross & Co., Inc. Page 84 1 And here is the effect of sodium 2 reduction in the control diet that is 3 basically a typical U.S. diet. And you see 4 this intensification of blood pressure 5 reduction as sodium is reduced down to 50 or 6 60 millimoles. 7 That also happened in the DASH 8 diet to somewhat of a lesser extent but sodium 9 reduction did effect the DASH diet. 10 Now here's a really clinically 11 important population, you know these are 12 patients over the age of 45 and mildly 13 hypertensive. And you see a real accentuation 14 of blood pressure lowering at low sodium. 15 So at the top bar, it's the sodium 16 reduction in the control diet. It goes down 17 2.1 -- blood pressure reduction, 2.1 from high 18 to medium and six from medium to low. Low 19 being proximately a one and a half gram goal 20 that you're looking at. And in the DASH diet, 21 same sort of thing. An accentuation of blood 22 pressure reduction when you go from medium to (202) 234-4433 Neal R. Gross & Co., Inc. Page 85 1 low down to around 1500. 2 Okay, now let's look at some 3 subgroups here. So this is African-Americans, 4 hypertensive and normotensive. And non- 5 African-Americans. And this is the sodium 6 change from 150 millimoles to 100. That's the 7 upper row. And the middle row from 100 to 50. 8 And here you can see that 50- 9 millimole difference, from 100 to 50, it 10 produces at least double the blood pressure 11 reduction in African-American hypertensives 12 and normotensives, non-African-American 13 hypertensives and about the same in non- 14 African-American normotensives. So a lot of 15 rationale for going down to the lower level or 16 at least trying to. 17 Okay, now there's an age 18 interaction also. There's a big effect of 19 sodium reduction in middle age and beyond. 20 So, okay, the red bars are blood pressure 21 reductions of sodium reduction with the 22 control diet. Okay, this is 23 to 41, middle (202) 234-4433 Neal R. Gross & Co., Inc. Page 86 1 age, middle age, older. 2 You see blood pressure -- sodium 3 is reducing blood pressure in the lower red 4 bars more and more as people get older. And 5 with the DASH diet, that would be in the 6 orange bars, you see the same sort of thing. 7 You see an accentuation of the effect in 8 patients, people who are in their 40s and 50s 9 and beyond. 10 So how do I sum this up? Well, 11 certainly evidence from the DASH sodium study 12 agrees with other evidence that there is an 13 accentuation of blood pressure lowering in the 14 1,500 milligram to 2,500 milligram range 15 compared to 2,500 to 3,000 or 3,500. 16 Most population groups are 17 responsive. It is about 70 percent of the 18 U.S. population would be in this responsive 19 group; that is over the age of 45, anybody, 20 African-American, any age, mild hypertensives, 21 any age, and this whole age thing, well, you 22 know, people under the age of 40 or 45 (202) 234-4433 Neal R. Gross & Co., Inc. Page 87 1 hopefully will at some point become more than 2 the age of 40 or 45 and become responsive to 3 sodium. So there is a potential for sodium 4 down to 1,500 milligrams to affect basically 5 everybody or everybody's potential. 6 So thank you very much for your 7 attention. I'd be happy to take questions. 8 CHAIR VAN HORN: Thank you very 9 much. We have about ten minutes. I'm going 10 to take executive privilege and ask just one 11 quick question in terms of what you've 12 presented in both cases. Certainly the 13 compelling data recognizing that 70 percent of 14 the population could be responsive, are there 15 any downsides that you can think of for 16 reducing the recommended level to somewhere 17 around 1,500 milligrams? 18 DR. SACKS: I am not aware of any 19 downside. There are long-term studies, long- 20 term follow-up of sodium reduction trials 21 showing benefit to cardiovascular events after 22 they showed benefit to blood pressure without (202) 234-4433 Neal R. Gross & Co., Inc. Page 88 1 any adverse effects identified. 2 So, no -- and then, of course, 3 there is a global natural experiment going on 4 because different locales around the world eat 5 different sodium levels. So nothing bad has 6 come up in that regard. 7 CHAIR VAN HORN: The other quick 8 question, then we'll open up to everyone else, 9 relates to the POUNDS LOST study and 10 everything that you so eloquently described as 11 far as choosing -- making it possible for 12 people to choose their approach. And with 13 ongoing support, which seems to be the key 14 factor in terms of both attendance at sessions 15 and/or ongoing tailored feedback to people who 16 manage to make these kinds of changes and 17 sustain them long term, it would seem that 18 that type of approach would, as long as 19 calories are reduced, be appropriate in terms 20 of helping people to make these energy 21 reductions in terms of their dietary intake. 22 Would you agree? (202) 234-4433 Neal R. Gross & Co., Inc. Page 89 1 DR. SACKS: Yes, I think really 2 the emphasis now should be on people finding 3 their way to a healthy diet that is within 4 guidelines for reduction of heart disease or 5 diabetes that they can stick with and learn 6 how to keep the calories down. And they need 7 some type of support. Now, of course, we did 8 it in a very expensive way, but there have to 9 be ways devised that are going to do it 10 cheaply. 11 CHAIR VAN HORN: Excellent. 12 The group? Eric? 13 MEMBER RIMM: This is Eric Rimm. 14 If I could lead the witness a bit more, just - 15 - you know, I think -- and it is not fair, 16 Frank, you haven't -- I mean you talked about 17 the Israeli study, but I wanted to dwell on 18 your study and the Israeli study together 19 because they were both, you know, probably the 20 best, well done, long-term trials of diet 21 composition and weight loss. 22 And if you look at the 2005 (202) 234-4433 Neal R. Gross & Co., Inc. Page 90 1 Dietary Guidelines that specifically say that 2 fat intake should be between 20 and 35 percent 3 of calories from fat. And since that time, 4 now your study has published and the Israeli 5 study has published, and both studies used 6 intervention arms or experimental arms that 7 use 40 percent of calories from fat. And both 8 of those were successful in weight loss when 9 there was support. So do you think there are 10 still grounds to have a 20 to 35 percent of 11 calories of fat range for the amount of fat 12 that is consumed? 13 DR. SACKS: Well, personally, I 14 think maybe we don't need any type of range, 15 you know, for recommended fat intake or even 16 macronutrient intake, that really we could 17 work our recommendations based on foods. But 18 specifically what you're saying, is there a 19 problem with 40 percent fat? No, I don't 20 think so. In fact, there are benefits for the 21 risk factors if it is the right fat obviously. 22 And that's the key. If you recommend high (202) 234-4433 Neal R. Gross & Co., Inc. Page 91 1 fat, will people really eat the beneficial 2 fats. 3 CHAIR VAN HORN: Tom? 4 MEMBER PEARSON: This is Tom 5 Pearson. Thanks for that presentation, Frank. 6 I had a question about the 7 physical activity part of the POUNDS LOST 8 study. You had 90 minutes per week 9 recommended. And I was just wondering the 10 extent to which you saw compliance with that 11 and if there was any specific interaction with 12 compliance with exercise and the effectiveness 13 of those four diet arms, which, of course, had 14 different components, which may, in fact, have 15 a little different responsiveness to physical 16 activity. 17 DR. SACKS: Well, that is an 18 interesting question. And we're actually 19 looking into that kind of thing now. But I 20 can just tell you that different adherence 21 measures, for example group participation, 22 individual participation, use of the computer (202) 234-4433 Neal R. Gross & Co., Inc. Page 92 1 web-based thing, physical activity, they are 2 all very inter-correlated. So I suppose that 3 they all would be related to weight loss. But 4 we're looking into that. 5 CHAIR VAN HORN: Cheryl? 6 MEMBER ACHTERBERG: Cheryl 7 Achterberg. You intimated in your 8 presentation that your patients tended to 9 drift back to the dietary pattern that they 10 had before the intervention. And I was just 11 wondering how you might reconcile those data 12 with immigration studies where people, in 13 changing residencies, dramatically change 14 their dietary patterns. So what do you do 15 with that? 16 DR. SACKS: Well, I think -- okay, 17 so maybe I overstated it. So they did -- they 18 drifted toward their previous macronutrient 19 intake. But they didn't go get to that point. 20 So you might say there is partial movement 21 toward the previous. 22 Now, you know, if they were (202) 234-4433 Neal R. Gross & Co., Inc. Page 93 1 assigned, let's say, to high fat but they are 2 used to eating a low fat diet, that's where 3 they kind of drifted to. So that's -- you 4 know, it just worked that way in any of the 5 groups. Now that doesn't mean we don't know 6 whether they ate the same foods because we 7 recommended healthy foods on all the diets. 8 But in terms of macronutrient intake, they 9 drifted toward that because that was the focus 10 of the study. 11 CHAIR VAN HORN: Larry? 12 MEMBER APPEL: Yes, thanks, Frank. 13 I have two questions, different 14 fronts. You know, in some of the studies 15 we've done we've calculated Framingham risk as 16 an outcome variable. And I didn't see that in 17 your paper. And I was wondering if it was 18 done and if all four diets led to the same, 19 you know, change in Framingham risk. 20 And the second question is 21 distinct having to do with satiety. You 22 mentioned you didn't see any changes in (202) 234-4433 Neal R. Gross & Co., Inc. Page 94 1 ratings. And yet, you know, we did OmniHeart 2 where we see very distinct, you know, changes 3 in satiety. So I'm just wondering, you know, 4 was there -- can you explain? 5 DR. SACKS: Okay. Well, let's 6 see. Yes, Framingham risk, yes, we were 7 thinking about doing that. The problem with 8 Framingham risk is it doesn't -- you know, our 9 outcome variable, body weight change, doesn't 10 really figure into Framingham risk. So that's 11 sort of a problem. 12 And it would deal with the 13 cholesterol, the HDL, the blood pressure, and 14 using those changes, the diets would probably 15 do more or less the same. But it is a good 16 thought. 17 And there are other risk -- there 18 are other, for example, PROCAM has 19 triglycerides in it and Reynolds has CRP. 20 We're going to get CRP measurements. So we'll 21 kind of wade into that. 22 And the second one was -- (202) 234-4433 Neal R. Gross & Co., Inc. Page 95 1 MEMBER APPEL: The satiety -- 2 DR. SACKS: Oh, the satiety -- 3 MEMBER APPEL: -- ratings where 4 you didn't see a difference but other studies 5 where you actually control -- you know, 6 typically smaller study or controlled feeding 7 studies do. So, you know, what is the 8 explanation? 9 DR. SACKS: Well, I don't know, 10 you know, if we had done satiety studies very 11 early after a week or two weeks, we might have 12 seen differences like these. But all I can 13 say is they didn't carry through to six 14 months. 15 And the difference between this 16 study, say, and the OmniHeart study is 17 OmniHeart we fed them to constant weight. So 18 we had plenty of obese people who we didn't 19 let lose weight. In this case, the whole 20 emphasis was losing weight. And there wasn't 21 any satiety difference at six months. 22 CHAIR VAN HORN: Rafael? (202) 234-4433 Neal R. Gross & Co., Inc. Page 96 1 MEMBER PEREZ-ESCAMILLA: Yes, 2 Rafael Perez-Escamilla. Consistent with your 3 follow-up support data showing, you know, that 4 it is important to support people in 5 maintaining the benefit in weight reduction, 6 you know we have found the same whether it is 7 a breast-feeding promotion, whether it is 8 Latinos improving their self-management of 9 diabetes at home. And for low income people, 10 it is very important to think about models 11 based on peer counselors, people from the 12 community that have successfully been able to 13 deal with the problem to become part of the 14 system. 15 Now the problem that we encounter 16 is the reimbursement issue. Like who is going 17 to pay for these. So the question is about 18 cost effectiveness. And what would be your 19 recommendations in terms of the type of cost 20 effectiveness research that we should do to 21 include these findings as part of a healthcare 22 reform in the country? (202) 234-4433 Neal R. Gross & Co., Inc. Page 97 1 DR. SACKS: Yes, I think that is a 2 tough topic. But I think it is very, very 3 important because our study and others say 4 that really that is the key. I mean it is 5 participation. It is counseling. 6 But now actually, I mean maybe one 7 could just do that in peer groups or 8 neighborhood groups or groups that people are 9 just doing it on their own that they don't 10 have to pay for anybody. Or maybe with the 11 internet they could do it. 12 But I don't know. I think your 13 idea of looking for models that could be done 14 at very low cost or no cost maybe after, you 15 know, the first couple sessions, may be the 16 way to go. I think that's probably where the 17 future is in the whole behavioral side of 18 this. 19 CHAIR VAN HORN: I'd like to just 20 go back to one issue related to your comment 21 about it doesn't matter what fat level, only 22 from the point of view of blood lipids and (202) 234-4433 Neal R. Gross & Co., Inc. Page 98 1 concerns about risks for cardiovascular 2 disease and juxtaposing what you were saying 3 related to weight control and the fact that we 4 do, of course, have a significant population 5 at risk for cardiovascular disease. And we 6 need to weigh and balance not only the total 7 fat but the qualitative nature of the fat. I 8 know from the Women's Health Initiative, for 9 example, we discovered that a recommendation 10 to lower total fat to 20 percent doesn't 11 necessarily achieve the lipid lowering 12 benefits unless there are qualitative changes 13 in the type of fat. 14 And it would appear from the slide 15 that you showed showing the differences in 16 lipids and insulin, et cetera, that, indeed, 17 you know, the group that had the lower total 18 fat and presumably lower saturated fat would 19 have lower LDL lowering. So I just wondered 20 if you would like to make just a further 21 comment related to that issue in addition to 22 what you said about the weight control issue. (202) 234-4433 Neal R. Gross & Co., Inc. Page 99 1 DR. SACKS: Oh, sure. Well, you 2 know, taking up -- you know, in comparison 3 with the OmniHeart study that Larry Appel 4 mentioned earlier, so I mean OmniHeart study 5 showed very clearly that unsaturated fat, you 6 know, lowers LDL very nicely. 7 So let's, so in our higher fat 8 group in our POUNDS LOST weight loss study, if 9 they had really eaten unsaturated fat, then 10 their LDLs would have gone down very well, 11 just as much or better than the low fat group. 12 So obviously they weren't quite doing that. 13 I mean they were probably having a little more 14 saturated fat than the low fat group. And 15 that's why there was a 6 percent LDL 16 differential between those groups. 17 So, you know, education on good 18 fat/bad fat -- I mean we really -- we worked 19 hard at it. And certainly there wasn't a 20 20 percent difference. But there was still a 21 small difference. So still that's an issue 22 that we have to work on. (202) 234-4433 Neal R. Gross & Co., Inc. Page 100 1 MEMBER APPEL: This is Larry 2 Appel. Frank, I didn't see actually what 3 happened in terms of saturated fat by diet in 4 your paper or your slides. So could -- you 5 know, there is this sort of mantra and maybe 6 it is knee jerk and wrong that if you reduce, 7 you know, as total fat goes, so does saturated 8 fat. Is that what you found? 9 I know you were trying to 10 emphasize the, you know, the better fats. But 11 in reality, were people, you know, was it 12 accomplished? You know you could sustain a 13 better fat profile even with higher -- even at 14 of higher fat. 15 DR. SACKS: Well, you know, you 16 got me on that. I just can't pull the numbers 17 out of my head. 18 MEMBER APPEL: Okay. 19 DR. SACKS: But they're published 20 actually in the article, the saturated fat 21 content on the four different diets. 22 CHAIR VAN HORN: Thank you again (202) 234-4433 Neal R. Gross & Co., Inc. Page 101 1 for an outstanding presentation. We really 2 appreciate all of your excellent comments. 3 And at this time, the group will 4 take a 15-minute break. And please return so 5 that we can hear Dr. Crawford promptly at 6 3:20. Thank you. 7 (Whereupon, the above-entitled matter went off 8 the record at 3:05 p.m. and 9 resumed at 3:24 p.m.) 10 CHAIR VAN HORN: All right. Thank 11 you for standing by. We are now ready to 12 proceed with our next presenter, Dr. Patricia 13 Crawford. 14 Dr. Crawford is Director of the 15 Robert C. and Veronica Atkins Center for 16 Weight and Health, an adjunct professor in the 17 Department of Nutritional Sciences and 18 Toxicology and the School of Public Health at 19 the University of California at Berkeley. 20 Dr. Crawford served as the Chair 21 of the Nutrition Subcommittee for all ten 22 years of the NHLBI Growth and Health Study, an (202) 234-4433 Neal R. Gross & Co., Inc. Page 102 1 epidemiologic study on the development of 2 obesity and heart disease risk factors in 3 African-American and white Girls. 4 Currently she is directing two 5 studies evaluating changes in children's 6 school lunch intake in the Berkeley School 7 Lunch Initiative Project and the Kansas City 8 Healthy Schools Partnerships Program. 9 Further, she is leading studies evaluating the 10 impact of legislation to improve the foods in 11 California schools examining implementation of 12 school wellness policies and evaluating the 13 impact of large-scale community interventions 14 to create healthy food and activity 15 environments for children. 16 Thank you. 17 DR. CRAWFORD: Thank you, Linda. 18 And I'm truly honored to be here. 19 And I applaud the Committee for your interest 20 in hearing the voices from the community in 21 your deliberations. 22 The Center's mission is to develop (202) 234-4433 Neal R. Gross & Co., Inc. Page 103 1 the science-based solutions to pediatric 2 overweight, particularly using the environment 3 and policy solutions. And over the last ten 4 years, we've conducted nearly 100 studies with 5 hundreds of community partners. 6 So today, rather than talking 7 about the findings from these studies, I'm 8 actually going to talk about the community 9 partners and their thoughts about the Dietary 10 Guidelines, the pyramid, and the guidance that 11 you all are providing. And these partners 12 include people from cooperative extension, 13 from WIC, teachers, school nutrition 14 directors, advocates, food stamp folks, 15 advocates, various coalition members and 16 leaders, and groups throughout the community. 17 So I thought I'd throw this in to 18 show you how we get information from our 19 partners. We all go jogging on the California 20 coast. 21 Okay, so I have four questions to 22 answer today. And the first one is rather (202) 234-4433 Neal R. Gross & Co., Inc. Page 104 1 elaborate. In what ways does my work suggest 2 that the current nutrition guidelines are 3 problematic when applied at the school or 4 community level? In what ways are they 5 effective? For example, how can school food 6 service managers and other settings 7 distinguish between foods that are the most 8 healthy and those that are the least? How 9 useful is the discretionary calorie allowance 10 for the lay public and food service manager in 11 planning amounts of various foods that should 12 be consumed? 13 So that's where we're going to 14 start. So in talking to those community 15 members, the first thing that came out is that 16 the current Dietary Guidelines are believed to 17 be credible and they are current and they are 18 comprehensive. And at many times in many 19 circumstances, they are very clear. At other 20 times, they are less clear. 21 And the community members that I 22 spoke with wanted to be sure that you (202) 234-4433 Neal R. Gross & Co., Inc. Page 105 1 understood that you are providing an 2 invaluable resource for them. And their 3 concerns really deal with the application and 4 the transmission and the translation of this 5 information. 6 And so I'm going to focus, for the 7 rest of the talk, not on all of the wonderful 8 things you are doing but on the concerns that 9 they have to make them even more useful at the 10 community level. So the first concern, and 11 I'm going to list four now, the first is the 12 lack of specificity. People want food-based 13 specifics for the translation of nutrient- 14 based guidelines. They want quantities, 15 types, classifications. They want to know how 16 they can meet the guidelines, not -- they 17 understand what the guidelines are. 18 And a good example are fruits and 19 vegetables. They said that they truly 20 understand. So if you can model, you know, 21 other guidelines based on that fruit and 22 vegetable one, it would be very helpful to (202) 234-4433 Neal R. Gross & Co., Inc. Page 106 1 them. 2 They said they understand 3 consuming a sufficient amount of fruits and 4 vegetables while staying within their energy 5 needs, two cups of fruit, two-and-a-half cups 6 of vegetables per day are recommended for this 7 reference intake with higher and lower 8 amounts, depending on the calorie levels, 9 choose the variety from the five vegetable 10 subgroups, all of that is very clear. 11 Then it falls apart with the other 12 groups. And largely that is because of 13 processing, how difficult that is. And I know 14 you all know that better than anyone. But 15 even in the example of the lean and low fat 16 foods, when selecting and preparing meat, 17 poultry, dry beans, and milk or milk products, 18 make choices that are lean, low fat, or fat 19 free, that sounds very clear. But the 20 questions that were raised are well, you know, 21 what about turkey hot dogs? 22 And what about bean? And, you (202) 234-4433 Neal R. Gross & Co., Inc. Page 107 1 know, people where I work don't drink milk. 2 So, I mean, should we really be using cheese 3 often? And those low fat cheeses aren't, you 4 know, aren't the ones that people eat. And so 5 there's just all kinds of questions about how 6 to get to that place. They don't -- they 7 can't translate what they are supposed to do 8 with that information. 9 So it's possible that as a result, 10 the fruit and vegetable messages are more 11 often transmitted and more often discussed. 12 For example, in nutrition education, the 13 primary topic in most of the nutrition 14 education in schools is fruits and vegetables. 15 So it is possible because of that clarity that 16 that is one of the reasons. I'm sure it is 17 not the only reason. But that is possibly one 18 of them. 19 And another situation, I did many 20 focus groups with WIC mothers a few years back 21 and found that through hundreds of pages of 22 transcripts, when they talked about healthy (202) 234-4433 Neal R. Gross & Co., Inc. Page 108 1 foods, they talked about vegetables. And we 2 know that the WIC messages cover all of the 3 groups. But they truly understood that 4 message. 5 And I don't know how much of that 6 might be because of that specificity. 7 Obviously there are other factors at work. 8 But I think it behooves us that those messages 9 are getting out, you know, strong to the 10 community. And we see it in different ways. 11 So another concern is the 12 complexity of the messages. We hear that 13 especially with nutrition education they 14 cannot seem to figure out how to take the 15 Guidelines or the pyramid into nutrition 16 education. It's complicated. You need a 17 computer for the pyramid. Five-a-day was just 18 simple and useful. 19 But the last one I think is 20 particularly interesting. A national set of 21 benchmarks and standards would be helpful in 22 developing nutrition curriculum. And I'm (202) 234-4433 Neal R. Gross & Co., Inc. Page 109 1 going to come back to that one again a little 2 bit later. 3 But people are really calling for 4 very concrete guidance. You know they don't 5 want to be out developing their own 6 curriculum. As much as we think they want to 7 do it, they want to adapt. They want to take 8 one, I mean they are busy doing what they do. 9 And so the more guidance that we can provide 10 for them on how to get from the guidelines 11 down to nutrition education would really be 12 helpful. 13 Another one, concepts regarding 14 the Dietary Guidelines include too much focus 15 on nutrients. So that one came out over and 16 over again. We eat foods and you talk about 17 nutrients. And clearly that's not completely 18 fair because foods are a very big part of the 19 Guidelines as well. 20 But take, for example, the effort 21 required by school personnel to decide on and 22 to monitor the competitive foods in California (202) 234-4433 Neal R. Gross & Co., Inc. Page 110 1 schools after we passed two important pieces 2 of legislation in 2005. Let me show you the 3 two pieces of legislation. 4 The first is Senate Bill 12, which 5 is for competitive foods. Snacks may have, 6 according to our legislation, and this is K 7 through 12 in California, no more than 35 8 percent calories from fat, 10 percent of its 9 calories from saturated fat, 35 percent sugar 10 by weight, 250 calories for a specific 11 portion. So very clear. Right? 12 Now this is a brief summary of 13 California Senate Bill 965. This is for 14 competitive beverages. They were passed at 15 the same time, K through 12. Beverages sold 16 to students must be from the following list: 17 fruit-based, vegetable-based drinks that are 18 at least 50 percent fruit juice without added 19 sweeteners, drinking water without added 20 sweeteners, milk products, electrolyte 21 replacement beverages with a cap on the amount 22 of sweetening. (202) 234-4433 Neal R. Gross & Co., Inc. Page 111 1 So completely different guidelines 2 for these two pieces of legislation. One more 3 related to the nutrients. One more related to 4 the foods. And we're doing a study right now 5 evaluating compliance with these two pieces of 6 legislation. And these are very common foods 7 and beverages that are sold in California 8 schools as competitive foods. 9 And which do you think -- the 10 beverages or the foods, when we've been out 11 surveying, are the most compliant to that 12 legislation? In 2007, we were supposed to 13 have 50 percent of the beverages were supposed 14 to be compliant to the legislation and 100 15 percent of the foods. When we went out, it 16 was much more likely that the beverages would 17 be compliant than the foods. Now there are a 18 lot of reasons. 19 There are more foods than there 20 are beverages, you know, more choices out 21 there. But one of them could have been it is 22 very simple to follow that legislation with (202) 234-4433 Neal R. Gross & Co., Inc. Page 112 1 the beverage categories, and it is really hard 2 to follow it with the food nutrient 3 categories. 4 Now look at this list. These are 5 some of the foods that we found when we were 6 out surveying competitive foods in schools to 7 see whether they were meeting the actual 8 legislation. So can you guess which one of 9 these, I mean you saw the criteria, might be 10 compliant and which are not or what percentage 11 of these might be compliant with California's 12 legislation? 13 And remember that was the fat 14 limits, that was the sugar limits. All of 15 them might be compliant, yes. Well, in fact, 16 it is even worse than that. Exactly half of 17 them are adherent, the yellow ones are 18 adherent and the red ones aren't. 19 And it behooves us to look and see 20 -- I mean say you are a school food service 21 director and you are out there and you have to 22 decide between Nature Valley strawberry yogurt (202) 234-4433 Neal R. Gross & Co., Inc. Page 113 1 granola bar and Nature Valley crunchy oats and 2 honey granola bar. No way. 3 So they're out -- these are in the 4 vending machines, they're in the school 5 stores, they are all over the campus in high 6 schools. And sometimes we have different 7 groups that are responsible for different 8 stores or different venues. 9 So this is really difficult for 10 schools to get to the place -- and they are 11 trying. I mean they really are out there 12 working very hard to get there. So I think 13 that it really helps us understand the kind of 14 things that they are up against because the 15 food supply is so complex now. 16 So also on too much focus on 17 nutrients, I wanted to share with you a quote 18 that I got from a school food service director 19 who is a dietitian in one of our large school 20 districts in California. She said, "As a food 21 service director, we now serve foods that 22 simply taste okay. It's low fat. It's high (202) 234-4433 Neal R. Gross & Co., Inc. Page 114 1 fiber. It's low sugar. It's trans fat free 2 with high nutritional value. It no longer 3 resembles real food. It no longer tastes 4 great or even good. We used to be able to 5 make small, fresh, satisfying chocolate chip 6 cookies. That has now been replaced by things 7 like fun-shaped whole wheat chocolate flavored 8 crackers." 9 "When food is not satisfying to 10 one's palette, the consumer is left wanting. 11 First we took out the fat, compensated with 12 more sugar. People considered the result to 13 be diet food and ate more resulting in an 14 equal or greater caloric intake. Next we got 15 excited about the sugars and made sugar the 16 villain, then trans fats, and now sodium." 17 So this is pretty difficult to 18 take. But she, being a dietitian, she said 19 ‘‘I am part of this problem.’’ But I'd like 20 you to share it with the Committee. 21 "We've become so nutrient focused 22 we've forgotten how to enjoy, appreciate, (202) 234-4433 Neal R. Gross & Co., Inc. Page 115 1 savor real food. There are far too many 2 confusing, conflicting rules and 3 recommendations. People trying to eat 4 healthily buy processed foods covered with 5 health claims. More defined nutrition rules 6 will not solve our problem. They will only 7 exacerbate it." 8 So this is, you know, this is from 9 somebody on the front line who has been doing 10 the job she has been doing for 30 years. And 11 I think it really expresses very clearly the 12 kinds of things that we hear when we're out 13 talking to people working in the schools and 14 working in the community. 15 So their concerns about the 16 Dietary Guidelines include a fourth issue. 17 And that's the use of discretionary calories. 18 And this one is quite different from the 19 other three because this was something that 20 was, you know, included in the Dietary 21 Guidelines last time that those working in the 22 community really love. (202) 234-4433 Neal R. Gross & Co., Inc. Page 116 1 So this is such a positive thing. 2 Now they're not using it much, and that's 3 because they are totally confused by how to 4 use it. But they know there is great 5 opportunity if they understood it more. 6 So this came out -- several people 7 mentioned that they've just begun to hear 8 about it, and it actually makes so much sense. 9 That foods -- some foods are core foods. And 10 then they have additional discretionary 11 calories added to them so they can begin to 12 explain that to the public and use examples. 13 The problem is trying to use the 14 examples. I've been using this example in a 15 class that I teach in community nutrition. 16 And I'm not sure. I've actually vetted with 17 somebody on the Dietary Guidelines Committee 18 last year. I vetted it with somebody at USDA. 19 And each one had slightly different opinions 20 of exactly how you calculate. 21 I mean should I be doing extra 22 calories from a doughnut by comparing it to a (202) 234-4433 Neal R. Gross & Co., Inc. Page 117 1 grain product that doesn't have the fat and 2 sugar? Now would that be the like toast? 3 I mean, so I put this in here 4 because I've tried hard to understand myself 5 how we get to those extra calories. And I'd 6 like, you know, I think that if you could 7 provide more guidance in this area, that we 8 can translate this kind of information for the 9 consumers. 10 And one of our advocate groups, 11 the California Food Policy Advocates said we 12 are using it, we're trying to understand it, 13 it is really working, and tell the Committee 14 that we would love to have a better, you know, 15 translation of this concept. 16 So question number two that I was 17 asked to answer. Have school wellness 18 policies utilized information from the Dietary 19 Guidelines? We're working -- a study we have 20 is Team Nutrition Local Wellness 21 Demonstration Project with the Department of 22 Education and two other states, Iowa and (202) 234-4433 Neal R. Gross & Co., Inc. Page 118 1 Pennsylvania. 2 And so I'm going to just summarize 3 briefly and say absolutely. This is really a 4 phenomenal way to get the Dietary Guidelines 5 information out to the community in a way that 6 it hasn't been out before. So by getting that 7 wording from the Dietary Guidelines into the 8 wellness committees in every school district 9 that receives federal funding, we are actually 10 putting out information that people at the 11 community level are talking about now. 12 So there are four summary points 13 here that the school wellness policy requires 14 schools to set goals for nutrition education. 15 So while many mention the Dietary Guidelines 16 or MyPyramid, interview data suggests that 17 they are having difficulty using that 18 information in nutrition education. But it is 19 in their wellness policy so they are trying to 20 make that leap and translate it. 21 Number two, they are using it, 22 many of them for competitive foods to put (202) 234-4433 Neal R. Gross & Co., Inc. Page 119 1 guidelines into their wellness policies. Some 2 schools are actually using the information to 3 set higher nutrition standards than USDA 4 requirements for school lunch. 5 And then the fourth point, many 6 policies are based on model policies. And so 7 that was where I wanted to come back to. The 8 more that you all, as a body, can create 9 models, they love lifting those models and 10 putting it into their own wellness policies. 11 And what that means is they will 12 then have to, and they will begin to really 13 work on, you know, translating that into 14 practice. But they do use policies. You can 15 see that they actually are using the language 16 that is similar in many, many of the 17 districts. 18 So while not a representative 19 sample, we are measuring and looking at 31 20 school districts in this Team Nutrition Local 21 Wellness Demonstration Project. And 30 of 22 them mention the Dietary Guidelines either (202) 234-4433 Neal R. Gross & Co., Inc. Page 120 1 explicitly for education or competitive 2 schools or at least referenced it. 3 And here's a chart showing you how 4 many did that. And this is with schools in 5 California, Iowa, and Pennsylvania. So the 6 largest part of the circle is with references 7 to the Dietary Guidelines information. But 8 the blue ones specifically mention the Dietary 9 Guidelines. And then there was just that one 10 school that didn't include Dietary Guidelines 11 at all, the information or the specifics. 12 So it does show that this is a 13 real opportunity to get the information out 14 there and to be discussed. And I will -- I 15 won't go over all these examples, but I'll 16 tell you that the wording is all over the map. 17 We just gave you some examples here of the 18 different kinds of wording that is in the 19 Wellness Policy. 20 The first one is very general 21 wording. The second one has some daily 22 recommendations, you know, the sodium issue. (202) 234-4433 Neal R. Gross & Co., Inc. Page 121 1 The next one here I thought was interesting 2 because in the Wellness Policy, the school is 3 trying to actually operationalize it. They 4 said that fat served on the side, no more than 5 twice a week. 6 And then the next one talks about 7 the variety and limiting certain things, the 8 wording right out of the Guidelines. And two 9 more examples, one of them on nutrition 10 education that they can use the MyPyramid or 11 they can link it to other kinds of education. 12 This is a California Wellness Policy. 13 And then the last one down here is 14 an example of another policy where nutritional 15 integrity is the level of performance that 16 assures that school-sponsored foods meet 17 recommended dietary allowances and dietary 18 guidelines. 19 So you can see it is all over the 20 map. But there are definitely patterns in 21 schools where certain language is picked up by 22 different states, and many of the schools (202) 234-4433 Neal R. Gross & Co., Inc. Page 122 1 within that state will have the same type of 2 language. 3 So a real opportunity with those 4 wellness policies. And we'll have a 5 conclusion to that study pretty soon. And 6 we'll have more information on it. 7 Question three, how can government 8 nutrition guidelines convey usable information 9 applicable to the school and community 10 settings? For example, how is the pyramid 11 being used? Has it been adapted? Or have 12 alternatives been developed by community 13 groups? 14 Well, we hear a lot about the 15 Guidelines and pyramid when we're talking to 16 our community partners. And I wanted to help 17 you focus here on the third one. The pyramid 18 is not helpful on a social marketing level. 19 So that was one of the messages that came out 20 that was very important, I felt. 21 And down here, it is reiterated in 22 a similar way. The pyramid is helpful for (202) 234-4433 Neal R. Gross & Co., Inc. Page 123 1 motivated individuals who want tailored 2 messages but it is hard to use to write a 3 curriculum. So I think this is a very clear 4 message about the application. 5 So alternatively, many, many 6 community folks are developing other ways to 7 take the information from the Guidelines and 8 the pyramid and to actually translate them 9 into tools that they feel are more applicable. 10 This one was developed by U.C. Cooperative 11 Extension and has been tested with the 12 Expanded Food Nutrition Education Program as 13 well as Food Stamp Education Program. The 14 staff just love it, and the clients love it. 15 And an article is coming out on the use of 16 this plate curriculum. 17 The Coalition of Food Banks in 18 California like the plate so much but they 19 wanted to add foods, pictures of foods, words 20 about foods. And you can see that this one 21 was adapted for Asian foods so they still like 22 the symbolism of the plate and they use it in (202) 234-4433 Neal R. Gross & Co., Inc. Page 124 1 their, you know, their education with the food 2 bank recipients. 3 This is another one that is being 4 used in California, Healthy Kids Meal Wheel. 5 And this one is interesting because of the 6 beautiful graphics you'll see. And then you 7 can see how meat is -- red meat is pulled out 8 from the lean protein group. And you can see 9 all the different sources of calcium here. 10 But I want to point out the 11 desserts over here on the little spoon and the 12 little pat of butter on the knife. Isn't that 13 cute? So -- but it is, it's being used in a 14 large school district. And, you know, kids 15 can really understand how it all fits 16 together. 17 And I must say, years ago when I 18 first saw the plate, I was working with the 19 Growth and Health Study where we were working 20 with adolescent African-American girls, and I 21 found that it was sort of irrelevant to the 22 kinds of foods that were being eaten for lunch (202) 234-4433 Neal R. Gross & Co., Inc. Page 125 1 by these teenage girls. They were having 2 chips and soda. And how does that fit on a 3 plate? 4 And now I've come full circle 5 working in these new studies with schools and 6 with other community groups that if we don't 7 continually show how foods can fit on a plate, 8 pretty soon we won't be eating foods that go 9 on a plate. And I have a beautiful picture, 10 which I didn't bring, of an actual school 11 lunch in one of the studies that we're doing 12 that shows a child bringing from home four 13 little packages that fit on the plate at 14 school. 15 And they just pulled apart each 16 package. And that was the meal. So you can 17 imagine how surprised we all were that you 18 can, you know, go and buy packages and create 19 a meal from these packages. So lots of 20 interest in this area. 21 Okay, so question four, so drawing 22 on my experience, what do you think the needs (202) 234-4433 Neal R. Gross & Co., Inc. Page 126 1 -- needs to be done at the level of the 2 federal nutrition guidelines to optimize 3 nutrition for Americans in the school and 4 community settings? And so at the end here, 5 I'd like to just provide a few 6 recommendations. One is to provide guidance 7 on what constitutes a healthy food. Be 8 simple. Be specific. Be clear. Give 9 examples. 10 Because what I've been learning 11 from working with these community partners is 12 that if we don't provide that very specific 13 information for them on what is a healthy 14 food, that they will do it themselves. And 15 let me give you just a couple of examples. So 16 one of my students did a survey of 17 restaurants, chain restaurants to look at 18 health claims. And out of 124 chain 19 restaurants, and this is just looking at the 20 websites, 33 say they have healthy menus or 21 items designated as healthy. 22 Seven say they have low calories, (202) 234-4433 Neal R. Gross & Co., Inc. Page 127 1 19 have health claims about low fat, eight had 2 health claims about low carb, four about 3 sugar, and one just says their entire menu is 4 healthy. Now it's not so much that they all 5 have different ways of determining what 6 healthy foods are, but it's that all of the 7 cutoffs and all of the criteria are different. 8 So think about you as a consumer 9 trying to make a choice between restaurants. 10 You're not sure which cutoff is better. And, 11 you know, so I think it is that kind of 12 confusion out there. 13 Another example of a healthy food 14 definition, I thought this was so original. I 15 was speaking to an elementary school teacher 16 in Oregon who wanted her students to bring a 17 healthy snack every Friday. She said but how 18 do I know what a healthy snack is? I mean I 19 could tell them just to bring a fruit and 20 vegetable because that one I understand. But 21 I wanted to broaden it to a healthy snack. 22 So finally she said, "I talked to (202) 234-4433 Neal R. Gross & Co., Inc. Page 128 1 everybody, and I came up with a definition 2 that worked for me." She said, "I taught the 3 kids how to read the ingredient labels on all 4 their packages. And I taught them all the 5 ways to describe sugar. And then I said if 6 that is one of the first three ingredients, 7 then it is not called a healthy snack in my 8 classroom." 9 So it's a very practical way to do 10 it. It doesn't hit the fat issue at all. But 11 it definitely worked for her. And she said 12 the snacks have been pretty good. 13 So another example was -- this was 14 in the newspaper. After voting to introduce 15 increased lunch prices next year in Kentucky, 16 a school board member said you can cut lots of 17 costs in a food service program by getting 18 prepackaged foods and stuff that is not 19 healthy out. 20 So this is somebody who has 21 decided that it is more the packaging. The 22 foods that come in packages are less healthy. (202) 234-4433 Neal R. Gross & Co., Inc. Page 129 1 So different definition. 2 And this is a school nutrition 3 director who said children will eat real whole 4 foods. And she's saying that that is healthy. 5 So lack of processing is healthy. 6 So you can look at this in any 7 different way. This is an adoption of sort of 8 the Dietary Guidelines that have been adopted 9 into a food guide by the Central Food Bank of 10 New York. And now food banks in California 11 are adopting it for their use because they are 12 struggling with trying to bring healthier 13 foods into the food banks. 14 And then to get -- to reduce 15 donations of the least healthy. So they said 16 we can encourage fruits and vegetables. 17 That's the green. And we can discourage sodas 18 and candy. We can sort of understand that. 19 But all the foods in the middle, 20 they have no idea where to -- you know, many, 21 many discussions -- I mean this is just an 22 enormous problem for somebody working in the (202) 234-4433 Neal R. Gross & Co., Inc. Page 130 1 community. 2 We can do the red part a little 3 bit. We can do the green part a little. But 4 we don't know what to do with all that yellow. 5 I mean is there some way we can figure out 6 which are the healthiest foods? So their goal 7 is right on target but they don't know how to 8 operationalize it. 9 So all suggested we want help 10 defining healthy foods. Can you use colors? 11 Can you use checkmarks? And can you even use 12 a system like we rate restaurants with A for 13 best choice, B for okay, C for worst choice? 14 We need prompts to change 15 behaviors. And we need guidelines that will 16 actually guide dietary practice. 17 This is Armando Valdez, who works 18 with the Latino population in California. And 19 he said, "We really need help on how to guide 20 those choices." 21 And, finally, the last one is near 22 and dear to my heart as a researcher. Someone (202) 234-4433 Neal R. Gross & Co., Inc. Page 131 1 from the community said last week when I was 2 asking about these questions, "We need more 3 translational research for the Guidelines and 4 the pyramid." 5 I love that. So -- and he ended 6 by saying, "If schools are serving 30 million 7 students per day and meeting regulations 8 crafted from the Guidelines, how can only two 9 percent of the children be meeting it?" 10 Somebody had better research and 11 figure out exactly what is happening? You 12 know why do we have such a disconnect here. 13 So I thought that was a very interesting quote 14 to end with. 15 So thank you again for the 16 opportunity to come and share some of the 17 voices from the schools and communities. I 18 know they appreciate your interest in what 19 they're doing and the problems that they are 20 having. And really look forward to the new 21 Guidelines. 22 CHAIR VAN HORN: Thank you so (202) 234-4433 Neal R. Gross & Co., Inc. Page 132 1 much, Pat. 2 And in the interest of time, we're 3 just going to take maybe one or two questions 4 now. But then open after Mike gives his 5 presentation, to see if we have further 6 questions. 7 Tom? 8 MEMBER PEARSON: The whole field 9 of guideline development obviously has 10 evolved over the years. Certainly we have 11 been provided descriptors of the strength of 12 evidence supporting recommendations. 13 You've provided a number of models 14 here. Your healthy plate, the Local Wellness 15 Policy, et cetera. How many of those have 16 really been subjected to rigorous randomized 17 evaluations so that we can, in fact, 18 generalize them beyond California or wherever? 19 Because what we've been doing for 20 30 or 40 years is anecdotal discussion of 21 things that look nice for which there is no 22 evidence to say they are worth our time and (202) 234-4433 Neal R. Gross & Co., Inc. Page 133 1 effort. 2 DR. CRAWFORD: No, I think that 3 they really do want that research. And they 4 do want the evidence because they are just 5 struggling in the community to do what staff 6 say works, what people say they love, you know 7 what they understand. But we want those 8 trials. 9 CHAIR VAN HORN: Chris, go ahead. 10 MEMBER WILLIAMS: I think it is 11 interesting that children get about 30 percent 12 of their calories from snacks. But the 13 problem is that they don't always want 14 something that we might consider to be 15 healthy. 16 I recall a little boy whose mother 17 had just gone apple picking. And every day 18 for five days he got an apple. And finally on 19 the fifth day, he said, "Mom, do you think 20 just one time I could have something that is 21 not healthy?" 22 And I think we have to find a (202) 234-4433 Neal R. Gross & Co., Inc. Page 134 1 balance somehow between sometimes healthy 2 snacks and sometimes snacks that are pretty 3 good but not quite as top of the line, maybe 4 thinking about healthy, you know, children 5 having two snacks a day, maybe one healthy one 6 and one free one or getting a little more 7 balance there because I think all of us don't 8 want to be totally restricted to a certain 9 category of foods or beverages. 10 DR. CRAWFORD: And that's what 11 they would love. They would love a checkmark 12 system or a color system. Have these every 13 day. Have these on some days. Have these 14 once a month. I mean that is exactly what 15 they want to operationalize it. 16 They said we can take that message 17 to the community. But nobody is willing to go 18 out there and say well, which foods fit on 19 that first level? And on that second level? 20 So you are right on target. 21 CHAIR VAN HORN: Thank you again, 22 Pat. That was excellent. (202) 234-4433 Neal R. Gross & Co., Inc. Page 135 1 We're going to move right along to 2 give time for our next speaker who is Dr. 3 Michael Hamm. He is the C.S. Mott Professor 4 of Sustainable Agriculture at Michigan State 5 University. 6 He is currently affiliated with 7 the Departments of Community Agriculture, 8 Recreation, and Resource Studies, Crop and 9 Soil Sciences, and Food Science and Human 10 Nutrition. 11 At MSU, he is co-founder of the 12 C.S. Mott Group for Sustainable Food Systems, 13 which engages communities in applied research 14 and outreach to promote sustainable food 15 systems. 16 Dr. Hamm's active research areas 17 include community food security and 18 sustainable food systems. 19 Thank you so much for coming. 20 DR. HAMM: Well, thank you so much 21 for having me. I really appreciate it. And 22 I'm honored to be here. (202) 234-4433 Neal R. Gross & Co., Inc. Page 136 1 You can tell there have been a lot 2 of mergers in academia because I'm in three 3 departments and every one has a conjunction in 4 the title. So welcome to my world. 5 So what I wanted to do today was 6 kind of step back a little bit and talk about 7 the relationship of the Dietary Guidelines to 8 sustainability. And maybe think about how 9 they relate to one another. 10 And one of the things -- one of 11 the questions -- I was asked to address four 12 questions. And I'll just kind of take them 13 more or less in order. And one of the 14 questions was does sustainability of our food 15 supply relate to the Dietary Guidelines? 16 And I'd like to just think a 17 little bit about fruits and vegetables for a 18 second because that's one where it is pretty 19 clear that Americans, on average, eat far less 20 than they should. And I'd like to just run a 21 scenario by you which is tomorrow morning, 300 22 million Americans wake up and all decide you (202) 234-4433 Neal R. Gross & Co., Inc. Page 137 1 know what, we've been doing it wrong. We're 2 going to follow the Dietary Guidelines and eat 3 all the fruits and vegetables we're supposed 4 to. 5 Three things would happen. The 6 first thing that would happen is there would 7 be a run at the produce section of every 8 grocery store in the country. And they'd be 9 divorced of everything. 10 The second thing that would happen 11 is that every dietitian in the country would 12 faint. 13 (Laughter.) 14 DR. HAMM: And the third thing 15 that would happen is that we'd find out we are 16 13 million acres short of production. 17 So the reality is is that -- and 18 this is ERS data actually that came out soon 19 after the 2005 Dietary Guidelines were brought 20 out. And so what we know is that there is a 21 disconnect in reality between our agricultural 22 production and our Dietary Guidelines for a (202) 234-4433 Neal R. Gross & Co., Inc. Page 138 1 healthy diet. 2 So 13 million acres, just to give 3 you an idea of what that is, 13 million acres 4 is two to three Californias of production. 5 And California currently produces 50 percent 6 of our fresh produce that we domestically 7 produce. It is a lot of produce. 8 Now if we step back from that for 9 a second and say okay, so let's say we wanted 10 to get to the Dietary Guidelines with respect 11 to production. Let's say we can create the 12 demand. Now we've got to create the supply. 13 What would it take to do that? 14 Well, one thing to keep track of 15 is is that it is not a static issue and it is 16 a consistently moving target. This is a 17 graphic out of the American Farmland Trust. 18 All those areas in red on the map of the 19 United States are areas of highly productive 20 farmland and under high threat of development. 21 Now that map came out prior to the 22 current economic crisis. And so development (202) 234-4433 Neal R. Gross & Co., Inc. Page 139 1 actually across the country has slowed down 2 quite a bit. And so it's put less pressure on 3 it. 4 We can anticipate, though, as the 5 economy recovers that those pressures are 6 going to be back on to a large extent. 7 In fact, they estimate that right 8 now 86 percent of the fruits and vegetables 9 that are produced in this country are produced 10 in the path of development. 11 That is the land that they are 12 produced on is under threat of development, 86 13 percent. Sixty-three percent of our dairy is 14 in the path of development. 15 In other words, right now we under 16 produce what we need for a healthy diet by 13 17 to 14 million acres. And what we do produce 18 is in danger of not being there at some point 19 down the road. 20 Now right now, we produce half of 21 our domestic fruits and vegetables in 22 California. And I would argue we need (202) 234-4433 Neal R. Gross & Co., Inc. Page 140 1 California right now because we need that 2 production. 3 And what we also know is is that 4 California, if we step back even a little bit 5 further, California's production is under 6 threat right now, too. The Central Valley, in 7 the New York Times about three weeks ago, they 8 indicated the Central Valley is going to have 9 about 800,000 acres less production this 10 summer. Why? Because they've had a drought 11 for three years. 12 If climate change scenarios are 13 anything close to right, there is anticipation 14 that they could lose as much as 70 percent of 15 the snowpack runoff that services irrigation 16 for California agriculture. 17 That snowpack runoff in other 18 water supplies also services the population in 19 California, a population that tomographers say 20 may grow from 36 million to 50 million by 21 2050. Another 14 million people needs water, 22 needs land to live, needs land for roads to (202) 234-4433 Neal R. Gross & Co., Inc. Page 141 1 move around, and needs land for businesses. 2 All of those things do two things. 3 They take land out of production. And they 4 take water out of production. 5 And so one of the things that we 6 can anticipate, that we can project, is that 7 20, 30 years from now when my ten-year-old 8 daughter is 30, 40, 50 years old, California 9 may well not be doing what California is doing 10 now. 11 So what that means is from a 12 standpoint of ensuring a healthy food supply 13 now and into the future, we have to think not 14 just about where we're getting our food now 15 and what we may need to do to boost that 16 production but how are we going to think about 17 a sustainable food supply ten, 20, 30 years 18 down the road. 19 And I would argue that one of the 20 things we need to think about right now is how 21 do we go about preserving that production in 22 places that are highly productive right now. (202) 234-4433 Neal R. Gross & Co., Inc. Page 142 1 And how do we think about redistributing 2 production across the country? 3 If you go back to a census of 4 agriculture from the `30s or `40s, you would 5 find that just about any county in the United 6 States had a more diverse agricultural 7 production system than it does today. We've 8 concentrated our production into production 9 centers across the country for a whole lot of 10 economic and logistical reasons and climatic 11 reasons. 12 But the reality is is that many, 13 many places in the country have the potential 14 to produce a much broader array of fruits and 15 vegetables, a much broader array of animal 16 products than they currently do. And in many 17 of the advocacy groups that I work with, 18 that's called local food systems. 19 In one vernacular, we can think of 20 that as national security. In another 21 vernacular, we can think of that as economic 22 development potential. There's all kinds of (202) 234-4433 Neal R. Gross & Co., Inc. Page 143 1 ways we can think about it. 2 I think from our standpoint, the 3 way that we should think about it is how do we 4 think about enhancing the public health of the 5 American population, not just now but for the 6 next 20, 30, 40, 50 years. 7 So that brings us to the next 8 question, which is should we think about more 9 than food as nutrition but also consider other 10 food attributes? And there's a lot of 11 attributes that people want to put into food 12 today. 13 You can go out and get coffee 14 certified five different ways. You can go out 15 and get food that is organic and it is fair 16 trade and it is bird friendly and it is 17 environmental and there is animal welfare 18 characteristics. There's all kinds of 19 attributes that different consumers in the 20 marketplace are looking for. 21 And I'm not really concerned about 22 that right now. And I'm not really sure that (202) 234-4433 Neal R. Gross & Co., Inc. Page 144 1 is a concern of this Committee. But what I do 2 think is is that when we think about the food 3 system and we think about the food supply, 4 what we think about as moving towards a 5 greater sustainability that can enhance the 6 public health of the population, we think of 7 it not as a simple problem because it's not a 8 simple problem. 9 In fact, it is what we think of as 10 a wicked problem. A wicked problem is a 11 problem for which there is not a solution. 12 There are improvements in the situation. It 13 is a problem in which it is not a linear 14 science problem because human values, morals, 15 perspectives, culture, religion, all kinds of 16 human attributes and things that make up the 17 human community come into play. So there's 18 differences of opinion. 19 If I asked you all to define what 20 sustainability was, we'd come up with a whole 21 bunch of different answers to that question. 22 We'd start about the triple bottom line and go (202) 234-4433 Neal R. Gross & Co., Inc. Page 145 1 through all kinds of scenarios about what 2 sustainable is. 3 And so to a large extent, I don't 4 think defining a sustainable food system is 5 actually possible. What I do think is 6 possible to do is to think about what kinds of 7 attributes, what kinds of characteristics 8 would we look for in moving that food system 9 towards something that was more sustainable 10 over the long term and that could help enhance 11 the health of the population. 12 I think it would look locally 13 integrated. I think we have to re-disperse 14 our food production across the landscape of 15 the United States. I think we need to do that 16 and I think we need to do it fairly quickly. 17 I think it would be community 18 based and I'll talk about that in a second 19 with respect to economic development. I think 20 there are ways to use the food system and the 21 food supply as tools for other issues that we 22 have in our communities that allow public (202) 234-4433 Neal R. Gross & Co., Inc. Page 146 1 health people to participate in things like 2 economic development and community development 3 and youth education to a greater extent than 4 we probably are right now. 5 I think we would try to have food- 6 secure communities. I mean I am in Michigan. 7 I've been there six years. There's never 8 been a balanced budget since I've been there. 9 I do a lot of work in Detroit 10 which has a very high unemployment rate. And 11 I look at the upper part of the Lower 12 Peninsula in Michigan which has actually the 13 highest unemployment rate in the state at 18 14 percent. 15 You know our state has an official 16 unemployment rate of 13 percent. That's very 17 high. And it's not going to get any better in 18 the near future. 19 I think it is an -- we would see 20 it as an opportunity to connect to other 21 issues, which I'll talk about more directly in 22 just a second. (202) 234-4433 Neal R. Gross & Co., Inc. Page 147 1 I think it would focus on health 2 and on healthy. From an agricultural 3 standpoint, how do we build healthy soils so 4 that those soils can nurture plants now and 5 into the future? How do those healthy soils 6 build healthy plants, grow healthy plants, et 7 cetera, down to healthy people? And I think 8 it would be diverse, which is another topic 9 for another day. 10 So many people -- I know the 11 Oxford Dictionary in 2008 declared localvore 12 the word of the year which is kind of 13 interesting in many ways and kind of fun. And 14 also unknowable in terms of what that word 15 really means. 16 For many people in the local food 17 movement, their idea of local is is that 18 everything should come from local sources. If 19 it is coming from a global source, it's 20 probably bad. If it is coming from across the 21 country, it's probably bad. And I actually 22 don't think that is true whatsoever. (202) 234-4433 Neal R. Gross & Co., Inc. Page 148 1 I think for a whole lot of 2 reasons, that we don't have time to go into 3 here, we should have a dynamic blend in our 4 food system that includes local, direct source 5 local like farmers markets and CSAs, indirect 6 local source like what we might see at a farm- 7 to-school programs in our K through 12 school 8 meals program, in restaurants, in grocery 9 stores. 10 But we also want to get stuff from 11 regional, from national, and from global 12 sources. The issue, I think, and where I sit 13 is is that we've tipped the scales so far that 14 we've forgotten about that local piece. Now 15 it is, of course, hot in the literature -- the 16 locals, the new organic, everybody wants to 17 buy local. It's a big topic. 18 And so the trick is how do we 19 rebalance the portfolio of where our food 20 comes from and use that in such a way that we 21 can, in fact, improve the healthfulness of the 22 food supply? (202) 234-4433 Neal R. Gross & Co., Inc. Page 149 1 Now, I live in Michigan. I was in 2 New Jersey for 20 years. I was in New York 3 for six years before that. But I grew up in 4 the Midwest. But I'm from Michigan. We're 5 seasonally challenged. 6 You know we have about a six-month 7 growing season at best. And so the question 8 is is okay, this whole local stuff, are there 9 ways from a production standpoint, in fact, to 10 generate fresh fruits and vegetables in a time 11 of year when we really shouldn't be doing that 12 because there is that on the ground. 13 Well, and the answer to that is -- 14 and can you do it sustainably? And the answer 15 to that is probably yes. What you are seeing 16 there is -- would probably -- you would say 17 that's a greenhouse. But the reality is is 18 that greenhouse has no fossil fuel energy 19 being used for heat. Any heat that is in 20 there has come from the sun and it's stored 21 heat down in the ground. 22 That hoop house has a double layer (202) 234-4433 Neal R. Gross & Co., Inc. Page 150 1 of plastic on it with about a 40-watt fan that 2 blows air between those two layers. Think of 3 it as double pane glass on your windows and 4 the insulation value. 5 Then inside there is another layer 6 of plastic over the beds. Inside there, in 7 Michigan, the environment of those plants is 8 about my hometown of St. Louis, Missouri. And 9 so you've moved about three growing zones 10 south. And you can grow about 30 crops in 11 there year round. 12 So this picture is actually taken 13 from the student organic farm at MSU where 14 they have a community-supported agriculture 15 farm of 75 families. And they provide them 16 fresh produce 48 weeks a year. The four weeks 17 is not because they can't grow it. It's 18 because they are taking time off because the 19 students are all gone. 20 So we can do that. So the point 21 is is that we can expand the season and think 22 about this in a way around economic (202) 234-4433 Neal R. Gross & Co., Inc. Page 151 1 development that I'll talk about in a minute. 2 Now here's the one that is a big 3 one for some people and that I was asked to 4 address. Is local healthier or more 5 nutritious? And the answer is I haven't got a 6 clue. There is absolutely no data to answer 7 that question. 8 I've seen a lot of literature that 9 says the ten reasons to buy local. And one of 10 them is always because it is more nutritious. 11 I can construct scenarios for you in which 12 local is more nutritious or less nutritious. 13 It all depends on how that crop is handled 14 from the moment it is harvested until the 15 moment it goes in your mouth. 16 So post-harvest management, as you 17 all know, once you harvest a crop, it starts 18 to die. And cellular senescence is the thing 19 that destroys fruits and vegetables. And so 20 how you manage that post harvest is critically 21 important. Okay? 22 Now all else being equal, it is (202) 234-4433 Neal R. Gross & Co., Inc. Page 152 1 traveling a shorter distance. It should be a 2 little bit more nutritious. The reality is 3 the percentages are probably not that 4 significant. If people actually went from 5 what they are consuming now to what they 6 should be consuming, that would be far more 7 significant than kind of any small bump you'd 8 get from the differences between local and 9 distance if they are all handled the same. 10 So I actually think that's kind of 11 a red herring of an issue in local versus 12 distant food. There's other things that 13 probably aren't. But I think that is one that 14 is. 15 Okay, the big one. Because, 16 again, I'm in Michigan and the only reason 17 that's relevant I think here is because we 18 went into the economic recession before 19 anybody else did. 20 And if I were a betting man, I'd 21 say we'll come out of it after everybody else 22 does because Michigan really did run for 100 (202) 234-4433 Neal R. Gross & Co., Inc. Page 153 1 years on the auto industry. And now we've got 2 to recalibrate who we are as a state 3 economically. 4 Now what does that mean? That 5 means that our State Department of Community 6 Health, which is the Public Health Department, 7 essentially has no money for preventative 8 health. If you take away the kind of 9 federally-mandated expenditures, there's 10 nothing left. 11 So what that means is is can we 12 think about -- and the other point to make 13 there is that in Michigan, as it is across the 14 country right now, if you're not having a 15 conversation about economic development, there 16 really is no conversation. That is the 17 conversation. 18 And so the question is is can we 19 think about this relationship of 14 million 20 acres needed in more production, which, if you 21 take us as three percent of the population, 22 that's a lot of acres, and relate that to (202) 234-4433 Neal R. Gross & Co., Inc. Page 154 1 landscape and land preservation for the future 2 and relate that to economic development and 3 public health. 4 So we asked ourselves that 5 question. And what we did was we said okay, 6 let's look at that public health gap, that 7 difference between what we do consume and what 8 we should consume. And let's just run a 9 scenario and say what would it mean to the 10 state economy if we could bridge that gap? 11 And we did it in a way in which we 12 said okay, let's assume -- you know, when you 13 run models, you make whatever assumptions you 14 want, you just have to justify them -- so our 15 assumption was was that people didn't 16 drastically change their diets. They just ate 17 more of everything they are currently eating: 18 more apples, more oranges, more bananas, et 19 cetera, et cetera. 20 And we threw out the things that 21 we don't grow in Michigan: apples, oranges, et 22 cetera. And then we took the things that we (202) 234-4433 Neal R. Gross & Co., Inc. Page 155 1 do grow in Michigan, which we grow a lot of 2 different things because we have a lot of 3 microclimates in the state -- the things that 4 we do grow and said how much of the year are 5 they available fresh? 6 So we get about a month of 7 strawberries. We get about two-and-a-half 8 months of tomatoes without season extension 9 technology. We get about ten months with 10 apples because of post-harvest and low 11 atmosphere storage -- controlled atmosphere 12 storage. 13 We said let's take that small 14 piece, which is about 15 percent of the total 15 bump in need that there is, and say what would 16 it mean to the economy if we actually produced 17 that in Michigan and ate that in Michigan with 18 ten million people. 19 And what it means is is that we'd 20 need to produce about 37,000 more acres of 21 produce in the state of Michigan to get that 22 15 percent increase in consumption. That 15 (202) 234-4433 Neal R. Gross & Co., Inc. Page 156 1 percent -- that 37,000 acres of production 2 adds 200 million dollars to the pockets of 3 farmers. And that 200 million dollars in the 4 pockets of farmers generates about 1,800 off- 5 farm jobs and at least twice that many on-farm 6 jobs for the production. 7 So the reality is by just bridging 8 about 15 percent of that public health gap, we 9 can generate a few hundred million more 10 dollars of economic activity and we can 11 generate about five or six thousand more jobs 12 in the state. 13 So in other words, we can -- we 14 firmly believe, and this is actually getting 15 some traction in the state, we can firmly link 16 increasing public health with local production 17 for local consumption with economic 18 development and job creation. And it is not 19 just job creation. It's all small business 20 creation because those farms that are 21 producing that are either small- or medium- 22 scale farms. And those are each businesses (202) 234-4433 Neal R. Gross & Co., Inc. Page 157 1 that we desperately need in the state. 2 Now we can then think about taking 3 and expanding that opportunity quite 4 dramatically because we can now take with 5 these high tunnels and say okay, that was just 6 seasonal availability without doing anything 7 special. We can now expand the season. 8 With these kinds of devices right 9 here, with those high tunnels, we can, for 10 example, normally where I live in Michigan, 11 we'll start getting field-grown tomatoes 12 sometimes after the 4th of July. And we'll 13 quit getting them sometime between October 3rd 14 and 10th when the first hard frost comes in. 15 With these high tunnels, we can 16 start tomato plants in there right now and 17 start getting tomatoes in early June. And we 18 can keep getting tomatoes until early to mid- 19 November. So we add about two months to the 20 fresh market for tomato season. 21 We can produce lettuce greens. We 22 can produce Asian greens. We can produce most (202) 234-4433 Neal R. Gross & Co., Inc. Page 158 1 root crops 12 months a year inside there 2 because we've got a research project right now 3 that's going on in three points in Michigan 4 with USDA money up in the Upper Peninsula with 5 Sioux St. Marie, Muskegon on the western side 6 of the state, and Ann Arbor. 7 Each of those are farmers markets. 8 And each of those has three farmers that has 9 one of those 30 by 96 high tunnels sited on 10 their farm. And they are producing to produce 11 for an early and a late market with the idea 12 that let's see if we can expand the season 13 under which people can get stuff fresh. And 14 early and late in the season can we expand the 15 diversity that is in the marketplace? 16 So we know that we can do the 17 production and the farmers are doing that. 18 The question is is if you grow it, will they 19 come? Will there be demand for it? 20 So David Conner in our group, who 21 leads this work, has gone out and surveyed 22 consumers at these farmers markets. And said (202) 234-4433 Neal R. Gross & Co., Inc. Page 159 1 okay, right now, when is the earliest you come 2 to the farmers market. Most of them say May 3 or later. And that's about right. May is 4 when you start getting in things like broccoli 5 and greens and early root crops like radishes 6 and things like that. 7 He said well, if there were these 8 high tunnels all over the place and there was 9 a lot of product coming in, when would you be 10 willing to come? And they said well, we'd 11 come a lot earlier. 12 He said well, what is the latest 13 you come right now? Well, September, sometime 14 between September and December depending. 15 What's the latest you would come, 16 again if there was product available? Much 17 later. 18 So we actually think that there is 19 an opportunity there to think about linking up 20 this extension of production in a sustainable 21 way with a market, okay. 22 Now the final question around that (202) 234-4433 Neal R. Gross & Co., Inc. Page 160 1 then is well, who has access to that product? 2 Because one of the things that was talked 3 about earlier is the fact that in many cases, 4 people on food stamps, in the SNAP program, 5 people with limited resources -- and with a 13 6 percent unemployment rate in Michigan, the 7 number that have limited resources is 8 climbing, how does everybody get access to it? 9 Well, of course, one of the 10 problems when we went away from paper food 11 stamps to electronic is the use of food stamps 12 at farmers markets collapsed overnight long 13 ago and now that is starting to come back. 14 And there's a lot of programs 15 around the country to basically get the card 16 readers at various farmers markets and make 17 that accessible. And there's various 18 strategies for doing that. 19 That still doesn't necessarily 20 allow for adequate resources to purchase what 21 people would like to purchase at those farmers 22 markets. And so just to give you an idea of (202) 234-4433 Neal R. Gross & Co., Inc. Page 161 1 the kind of thing that is going on out there 2 and one of the programs that is going on in 3 Michigan is to think about ways that we can 4 increase local fresh produce at corner grocery 5 stores. 6 For example, in Detroit, there's 7 something like a thousand places to purchase 8 food to take home inside the city of Detroit; 9 92 percent of those are liquor stores, filling 10 stations, and 7-11-type stores. There are 11 only 80 -- something like 80 corner grocery 12 stores, corner full-service grocery stores in 13 the city of Detroit and none of those are 14 supermarkets. There's not one supermarket in 15 the city of Detroit, okay? 16 So, the idea then with using youth 17 and youth farm stands and giving them some 18 entrepreneurial training so we start to break 19 this cycle of thinking that I can go from high 20 school to a lifelong union job that gives me 21 great wages and great benefits and retire, 22 which is now broken in Michigan, we need to (202) 234-4433 Neal R. Gross & Co., Inc. Page 162 1 think of other things. 2 So we train youth in how to sell 3 produce. And then they get produce from 4 farmers and sell it in the community. 5 There's now a thing called the 6 Michigan Farmers Market Association, MIFMA, in 7 Michigan which has done something really 8 wonderful, which is create an insurance 9 program so that farmers can get a million 10 dollar liability insurance at any farmers 11 market they sell at for only 200 dollars a 12 year. 13 If you check at many farmers 14 markets across the country, you'll find that 15 no farmer and no farmers market has liability 16 insurance. And they're just praying nobody 17 slips on a head of lettuce. 18 And then you need to link that to 19 all those farmers markets being EBT, 20 electronic benefit transfer accessible, many 21 of which aren't. And there is a program in 22 the state right now going on to try to get (202) 234-4433 Neal R. Gross & Co., Inc. Page 163 1 them card readers. 2 Then you've got to ask yourself, 3 okay, now there's product and there's 4 accessibility from the standpoint of people 5 who can use SNAP cards. Do they have enough 6 resources to do it? 7 Well, there's a program that 8 started with a foundation in Connecticut, 9 which is now moving into Michigan, of pooling 10 money from the philanthropic world to 11 essentially double the value of the bridge 12 cards at farmers markets for fresh produce. 13 So if somebody spends five dollars 14 of a SNAP card, they actually get ten dollars 15 worth of produce. And the farmer is paid out 16 of that philanthropic pool of money to help to 17 make up the difference so the farmer is not 18 the one that is not out in doing that. And so 19 that's going on right now. 20 And finally, and one of the big 21 issues here is in all of this, who is going to 22 grow the food? I mean if you look at the age (202) 234-4433 Neal R. Gross & Co., Inc. Page 164 1 of the farming population and if you look at 2 the traditional way that we generated farmers 3 in this country, which is kids coming off of 4 farms, going to the land grant, getting a 5 scientific basis for agriculture, and going 6 back to the farm, it's broken. And it's not 7 coming back any time soon. 8 To the extent that it is not 9 broken, there are kids going back. At MSU, I 10 just lectured yesterday in a class on crop and 11 soil science and about half those kids are 12 going back to their farm. But these are 13 three, four, five, six thousand-acre corn, 14 wheat, and soybean farms for the most part. 15 And so figuring out, in fact, 16 strategies for creating the next generation of 17 farmers is there, and there are things going 18 on in Michigan at Michigan State and in other 19 parts of the state. And there are things 20 going on in other places to recognize that we 21 have a large pool of immigrants that are in 22 this country either as migrant farm workers or (202) 234-4433 Neal R. Gross & Co., Inc. Page 165 1 former migrant farm workers or as refugees, 2 many of which have farming backgrounds and 3 want to go into agriculture. 4 We need different kinds of 5 training programs to work with these 6 populations and to allow them to become part 7 of the American fabric that produces food for 8 our tables. 9 The second group is we have a lot 10 of kids in colleges and universities very 11 interested in the environment. And they are 12 translating that interest into an interest in 13 farming. 14 It is primarily organic farming 15 because it comes from an interest in the 16 environment and everybody thinks that is more 17 environment. That's another discussion. 18 But I found at Rutgers we started 19 a student organic farm there and we never had 20 anybody with a farming background come there. 21 They were all interested in organic. And my 22 feeling was was that six weeks at 90-degree (202) 234-4433 Neal R. Gross & Co., Inc. Page 166 1 temperatures in July and August kind of burned 2 out the romanticism. And what was left was a 3 reality that it is hard to grow food. It is a 4 lot of work. 5 And so what these young people 6 came out of it with, if they didn't want to 7 farm, they came out with a profound 8 appreciation for people who did it. And if 9 they did want to farm, they came out with a 10 profound appreciation of what they needed to 11 do to get themselves ready. 12 And the third group is there are 13 some young people that live on farms today 14 that want to go into farming. And so there 15 are some programs out there with FFA and with 16 some other things that are engaging these 17 young people in looking at other things they 18 can do besides growing corn, wheat, and 19 soybeans. And that's, again, another 20 discussion. 21 So my point is is that there are 22 ways in communities and in states right now (202) 234-4433 Neal R. Gross & Co., Inc. Page 167 1 that strategies are being developed to help 2 create these linkages so that we don't just 3 say well, we need 13 million acres of fruits 4 and vegetables. Good luck. But, in fact, 5 ways where we can think about reinvigorating 6 our local economies and providing access for 7 everybody in the communities to these things. 8 So in summary, and I'll end, is I 9 think it is fair to say that most of the 10 activity around enhancing sustainability of 11 the food system in the U.S. can be considered 12 an opportunity with respect to the Dietary 13 Guidelines and can help achieve America's 14 goals in this regard. 15 And on that note, I will quit. 16 And say thank you. 17 CHAIR VAN HORN: Excellent. 18 Can we jump into questions, Mike? 19 Yes, Rafael? 20 MEMBER PEREZ-ESCAMILLA: Thanks, 21 Mike, for what I think is a very important 22 presentation. (202) 234-4433 Neal R. Gross & Co., Inc. Page 168 1 I think that the idea of free 2 trade agreements and the whole idea of 3 globalizing trade and so on, that was that we 4 shouldn't be so much concerned about these 5 issues because what we cannot grow here, 6 somebody else will grow it somewhere else in 7 the world. And we will be able to get it that 8 way. 9 Can you illuminate us a little bit 10 as to why, in spite of having that model in 11 place, we should be worried about local food 12 production? 13 DR. HAMM: Well, I don't know if I 14 can illuminate but I'll answer the question -- 15 I'm not sure I'll illuminate. 16 Here's one thing to keep in mind - 17 - and, again, I think that we can't just think 18 about where we are right now but think about 19 what are likely scenarios down the road over 20 the next ten, 20, 30 years? And recognize 21 that we could be wrong about those scenarios. 22 So I'm a big proponent of (202) 234-4433 Neal R. Gross & Co., Inc. Page 169 1 maintaining as many options as we can. Okay. 2 We import a tremendous amount of fresh 3 produce now. Every year we increase the 4 percentage of our domestic fresh produce that 5 we import from non-domestic sources. 6 Much of that is coming from 7 tropical areas of the world. If you look at 8 climate change scenarios, the ones that are 9 going to be the hardest hit are those in the 10 tropical regions of the world. 11 And so the probability is is that 12 places where we're sourcing a lot of that 13 fresh produce from now are going to experience 14 an increase in extreme events of climate, are 15 going to experience an increase in drought 16 events, and finally, those places are also 17 seeing an increase in population. And they 18 need a food supply for their own population, 19 too. 20 So, again, I'm not opposed to 21 global trade. I think it is an important 22 thing. But I think that we need to not lose (202) 234-4433 Neal R. Gross & Co., Inc. Page 170 1 track of our ability to produce a domestic 2 food supply at the same time. 3 And I think the only way we're 4 going to be able to ensure a domestic food 5 supply down the road is to spread it back out 6 across the countryside. 7 MEMBER PEARSON: As I've 8 disclosed, I may be the only farmer on this 9 board. But I'll tell you, Concord grapes in 10 upstate New York, a ton is 160 dollars, and 11 that's not the production costs. 12 DR. HAMM: Right. 13 MEMBER PEARSON: And one of the 14 reasons it's 160 dollars a ton is is that a 15 converted oil tanker from Asia will pull up 16 with -- loaded with grape juice, and basically 17 undercut the entire market. So I don't think 18 you can have it both ways. 19 We make beautiful table and juice 20 grapes, and most of my farmer friends are 21 basically converting to wine grapes. I think 22 we've got probably enough wine in this country (202) 234-4433 Neal R. Gross & Co., Inc. Page 171 1 -- my own view -- and it doesn't necessarily 2 fit into the Guidelines perfectly. 3 But certainly the fruit would. 4 And so I think you're going to really have to 5 break out of this cycle. It's a vicious 6 cycle, and the vicious cycle has to do with 7 market creation. 8 DR. HAMM: Right. 9 MEMBER PEARSON: And so I think 10 the Dietary Guidelines does have a role in 11 there. But the implementation of guidelines, 12 you know the Five-A-Day or whatever the 13 messages are, because certainly my farmers at 14 all ages are basically telling me that they 15 can't go ahead and continue to produce fresh 16 fruits and vegetables in the State of New 17 York. 18 DR. HAMM: Was that just a 19 comment, or would you like a response, as 20 well? 21 MEMBER PEARSON: Well, I was just 22 wondering how are you going to really create, (202) 234-4433 Neal R. Gross & Co., Inc. Page 172 1 because at some point, you're going to have to 2 talk about subsidization of price here, which 3 of course would get into a variety of NAFTA 4 and a variety of trade agreements, which -- 5 but currently the global market for fruits and 6 vegetables does not favor the American farmer. 7 DR. HAMM: In some products, 8 that's true. And Michigan experienced the 9 same thing with apple juice. About seven 10 years ago, Chinese concentrates started coming 11 in, and it killed about half of Michigan's 12 apple market overnight. 13 And now they're in the middle of 14 transitioning to a fresh market apple, which 15 of course is a different tree, and so it takes 16 time to do that. 17 That said, one example that I can 18 give you is is that out of the last farm bill, 19 there was a rule -- there's been a ruling put 20 out by USDA that it is not -- I don't want to 21 use the word, illegal, but let's just say it's 22 okay to use geographic preferencing as one of (202) 234-4433 Neal R. Gross & Co., Inc. Page 173 1 your characteristics when you're bidding for 2 the K through 12 school lunch program for 3 under 100,000 dollars. 4 Now what we just did last fall in 5 our state was work with the state legislature, 6 because what had happened in the past was -- 7 and states can be more restrictive on that, 8 and so can locals -- so the way it worked 9 previously is the feds was 100,000 dollars, 10 Michigan put an 18,000 dollar cap on it, and 11 many local school districts put a cap of zero 12 on it. Everything had to be competitively 13 bid, with no preferencing. 14 We got two bills passed in the 15 Michigan legislature last session that raised 16 the Michigan threshold to the federal 17 threshold. So the state's not a barrier. 18 And now we're working with -- 19 we've got a state farm-to-school coordinator 20 in my group. And she's working with school 21 districts across the state with food service 22 directors to learn how to work with farmers, (202) 234-4433 Neal R. Gross & Co., Inc. Page 174 1 and with farmers to learn how to work with 2 food service directors, recognizing that, for 3 a given bid, they've got 100,000-dollar cap, 4 which for the vast majority of the school 5 districts in the state, you're never going to 6 get to a 100,000-dollar cap on a single bid. 7 And in fact, there's a lot of 8 local product that's going to start flowing 9 into the school districts next year. There's 10 some now, and in Genesee County, for example, 11 right now there's two schools doing things. 12 There's 20 that are interested in doing it 13 next year. 14 So I think that there are -- we 15 have some leeway inside the federal 16 regulations right now to start doing some of 17 this. And I think we're going to end up 18 having to go further, and I think we are going 19 to end up having to make a decision of whether 20 we think that a healthy diet is, in fact, 21 something that we, as a population and as a 22 citizenry, think that everybody in our country (202) 234-4433 Neal R. Gross & Co., Inc. Page 175 1 should have access to. And that's a whole 2 other discussion. 3 But I think there are ways right 4 now that we can think about helping improve 5 viability of farms. And it's not going to 6 cover everything. The juices, I think, is a 7 real problem right now. But I think the fresh 8 market stuff is much less of a problem right 9 now. 10 CHAIR VAN HORN: Excellent points. 11 We have really got to move ahead, I'm afraid. 12 DR. HAMM: Yes. 13 CHAIR VAN HORN: But thank you so 14 much for your presentation, and I'm sure we 15 can talk a little bit later, as well. 16 At this point, we'd like to move 17 forward with our first of the seven 18 subcommittee updates. And first on the agenda 19 is Food Safety and Technology, which is 20 chaired by Roger Clemens. 21 MEMBER CLEMENS: I'm from 22 California. Where water flows, food grows. (202) 234-4433 Neal R. Gross & Co., Inc. Page 176 1 Thank you very much for your 2 patience. And thank you very much, Pat. And 3 Mike, thank you for those wonderful 4 presentations. We could definitely spend more 5 time with you. I know all of us have more 6 questions, more than time allows today. 7 It's our fortune to talk about 8 food safety -- I actually had some food safety 9 questions for Mike, but they'll have to wait 10 until on sidebar, I'm afraid. 11 Our group has been working 12 together, Rafael, with the excellent support 13 by USDA and DHHS, wonderful staff. Thank you 14 so much for your tremendous work and support 15 to bring this to where we are today. 16 Right now, a number of issues in 17 terms of behavior we'll want to address. We 18 also want to address a very hot topic in the 19 news in methylmercury in terms of fish 20 consumption. This will be in part a 21 collaborative effort with Dr. Pearson's team 22 with Fatty Acids to look at food consumption, (202) 234-4433 Neal R. Gross & Co., Inc. Page 177 1 and fish consumption in particular, and the 2 impact of methylmercury on other outcomes. 3 And lastly, we want to look at the 4 role of food allergies. Right now, with some 5 expertise from Rafael, I will turn the 6 lavalier over to Rafael to make a presentation 7 on this important topic. 8 MEMBER PEREZ-ESCAMILLA: Thank 9 you, Roger, very much. 10 What we're going to do is to give 11 you an update as to where we stand in terms of 12 the questions that we are working on and the 13 approaches that we are using together with the 14 staff. 15 First of all, what you see on this 16 slide are four questions for which we have 17 already developed PICO charts, and for which 18 the lit review has begun, especially those 19 labeled as priority level one, it means that 20 the work is currently underway, and those 21 questions labeled as priority level two, what 22 it means is that we are in the process, or at (202) 234-4433 Neal R. Gross & Co., Inc. Page 178 1 the early stage of the review, the lit review 2 process. 3 The first set of questions is 4 related to in-home food safety behaviors, a 5 lot of which fall within the framework. And 6 the second set of questions are related to the 7 risk of fish consumption. And in terms of the 8 priority level two questions, Roger will give 9 us an update on the new technologies related 10 to food safety and where we stand with regards 11 to food allergies. 12 First of all, with regards to in- 13 home food safety behaviors, we are documenting 14 and going very systematically through the 15 literature on describing what actually USA 16 consumers are doing at home in terms of food 17 storage, food preparation, handling, hand- 18 washing, which as we know has become a major 19 thing in the news lately, and also on washing 20 and cleaning techniques for the food 21 preparation utensils, equipment, food surface 22 preparation areas and so on, as well as on the (202) 234-4433 Neal R. Gross & Co., Inc. Page 179 1 washing and cleaning techniques for different 2 foods that are prepared at home. 3 The second set of sub-questions 4 related to in-home food safety behaviors 5 actually relate to understanding the evidence 6 behind different food safety behaviors, and 7 what impact they actually have at reducing 8 pathogen loads and subsequent risk of home- 9 based foodborne illnesses. 10 So it's not only documenting what 11 people are doing, but does it matter. Is 12 there scientific evidence to make 13 recommendations to the public at large as the 14 best way to store foods, prepare foods, wash 15 their hands, wash and sanitize their kitchens 16 and the foods that they consume. 17 We have developed the search and 18 sort plans, and we have made a strategic 19 decision, at least for now, that with regards 20 to describing the actual behaviors -- not only 21 behaviors, but also knowledge and attitudes, 22 we will concentrate mostly on studies done in (202) 234-4433 Neal R. Gross & Co., Inc. Page 180 1 the U.S., because it is the main target 2 population for the Guidelines. 3 But when it comes to the evidence 4 behind the different consumer behaviors, food 5 safety behaviors at home, and the changes in 6 food-safety outcomes, we will look at the 7 literature from both the U.S. and abroad. And 8 whenever we have to make a decision, we will 9 try to compare with evidence of countries that 10 are at the similar level of development as the 11 U.S. 12 We are not including in our search 13 the literature related to food safety issues 14 in the health care clinical settings, or 15 concentrating on specific food safety issues 16 surrounding a clinical condition, such as 17 renal disease, because the Guidelines are 18 supposed to target the healthy American 19 population over two years of age. 20 So with regards to in-home food 21 safety behaviors, the conclusion statements 22 will be drafted based on the review of (202) 234-4433 Neal R. Gross & Co., Inc. Page 181 1 information from two sources: the Federal 2 Consumer Food Safety Survey data from the FDA, 3 and the NEL, Nutrition Evidence Library review 4 that is being conducted. 5 And I must say that the staff has 6 already had a number of conference calls and 7 meetings with key people in the federal 8 government that are in charge of food safety 9 at different agencies. So we're also 10 gathering a lot of information that way. 11 So in terms of the Federal 12 Consumer Food Safety Survey data, it comes 13 mostly from the Food and Drug Administration 14 and Food Safety and Inspection Service. 15 And the survey, which is based on 16 a nationally representative sample, is applied 17 over the phone, was initiated in 1988, and the 18 latest data available is for 2006. The next 19 survey is planned for 2009. 20 So we do have an opportunity to 21 look at circular trends as to how food safety 22 attitudes, knowledge, and behaviors have been (202) 234-4433 Neal R. Gross & Co., Inc. Page 182 1 changing in the U.S. since the last Dietary 2 Guidelines were issued. 3 And we have received a lot of 4 support from the FDA to do additional data 5 that we request. And with having this goal in 6 mind, we had a teleconference with Amy Lando 7 from FDA, where she presented fairly recent 8 data to the subcommittee on food safety 9 trends, and we will continue working with her 10 to break down these results by socioeconomic, 11 demographic, and other type of characteristics 12 of the population. 13 So the first question that we're 14 concentrating on related to what consumers are 15 actually doing at home, we will have a good 16 snapshot as to what is happening at the 17 country level by different ethnic groups, 18 socioeconomic groups, and so on based on these 19 data from the CFSAN and the FDA. 20 The NEL literature review is 21 proceeding very well, I would say, and there 22 are already 16 studies that have been (202) 234-4433 Neal R. Gross & Co., Inc. Page 183 1 identified related to in-home consumer 2 behaviors in the U.S., 16 studies related to 3 food storage, food preparation and handling, 4 and seven studies related to favorable food 5 safety techniques, and how they relate to 6 different food safety outcomes. So we do have 7 enough work to do -- enough materials to read 8 already. 9 In terms of next steps, we will 10 conduct additional literature searches and get 11 the sort list approval for in-home consumer 12 behaviors related to hand-washing and the 13 washing and sanitation of food preparation 14 areas, food preparation utensils, and washing 15 and cleaning of foods at home. And also with 16 regards to the influence of several of these 17 techniques or behaviors on food safety 18 outcomes. 19 In terms of the federal programs 20 that are very key for understanding food 21 safety recommendations in the country, we know 22 that the 2005 Dietary Guidelines Advisory (202) 234-4433 Neal R. Gross & Co., Inc. Page 184 1 Committee Report basically fully endorsed the 2 four key messages from the FightBAC!(c) 3 campaign regarding the prevention of food 4 cross-contamination, proper storage of foods, 5 and so on. 6 And the 2005 Committee also looked 7 at topics that were not included, specifically 8 as part of FightBAC!(c), such as the 9 consumption of high-risk foods. So we're 10 following a very similar approach. 11 The FightBAC!(c) campaign, for 12 those of you that are not familiar with it, is 13 mostly based -- its origin dates back to the 14 Clinton Administration. It was launched in 15 1997. 16 And the scientific evidence behind 17 it is basically the application of the HACCP 18 principles -- HACCP stands for Hazards 19 Analysis and Critical Control Points, that 20 came from the food industry, and how that was 21 translated into the home setting. That's the 22 origin of FightBAC!(c). (202) 234-4433 Neal R. Gross & Co., Inc. Page 185 1 So the scientific evidence behind 2 it is fairly solid, and we anticipate that we 3 will continue endorsing that framework. 4 So a couple of federal agencies 5 within FDA, USDA, and the Partnership for Food 6 Safety Education have been contacted by staff 7 to get updates on what has happened since 2005 8 with regards to these campaigns and federal 9 initiatives, and if there is any published or 10 unpublished documents to show how they have 11 worked with consumers. 12 So we will concentrate on the 13 literature since 2004. And we may have to go 14 a little bit before then if we identify 15 relevant systematic reviews that we know some 16 of which we already know were published, one 17 of them, for example, in 2003. 18 But by most part, we will start 19 our search with 2004, and try to explain to 20 the public, you know, what is the scientific 21 evidence for the program FightBAC!(c) and the 22 other recommendations that are made with (202) 234-4433 Neal R. Gross & Co., Inc. Page 186 1 regards to food safety. 2 And very importantly, to identify 3 emerging issues related to food safety in the 4 -- according to the people that are running 5 those federal programs. And you will see that 6 we have identified some of them already. 7 There are a number of very useful 8 websites that you can check if you are more 9 interested in initiatives that are above and 10 beyond FightBAC!(c). And you have those in 11 front of your screen. The FDA launched a safe 12 handling of fruits and vegetables mini 13 campaign, and BACdown was an initiative 14 launched in response to the risk of Listeria. 15 And a lot of interest because of 16 Listeria on more emphasis on teaching 17 consumers how they can check their 18 refrigerator temperature, and which are the 19 ones, the temperatures that they should have 20 their refrigerators at. 21 So what are some of the emerging 22 issues related to food safety that have come (202) 234-4433 Neal R. Gross & Co., Inc. Page 187 1 up as a result of the interviews with key 2 individuals, or individuals in key positions 3 in federal agencies running food safety 4 programs? One of them that everybody 5 mentioned is related to microwave safety. 6 This is something that had not 7 been included before, and quite frankly, we 8 had not identified until these conversations 9 took place. There's lots of issues related to 10 how to safely microwave uncooked frozen foods 11 all the way to the sanitation of the microwave 12 ovens. And a lot of households have 13 microwaves now in the U.S. 14 Consumption of raw foods related 15 to the whole foods movement is an issue that 16 was identified by several of these key 17 individuals as an area that needs more 18 attention from us. And recommendations for 19 time and temperature relationships for 20 different foods. 21 Again, the consumers do understand 22 that it's important to store foods at the (202) 234-4433 Neal R. Gross & Co., Inc. Page 188 1 right temperature. And they know there are 2 time limits in terms of how long foods can be 3 left out and so on. 4 But when you put the two together, 5 the time and temperature, we need more 6 specific guidance. They need more user- 7 friendly information to be able to understand 8 and follow the recommendations. 9 So moving on from in-home food 10 safety behaviors, we have continued our work 11 on the benefit-risk analysis literature for 12 fish consumption. And as we know, the main 13 issue, the main concern is related to the 14 methylmercury levels in fish. 15 We have identified a number of 16 reports, some of them that have already been 17 published like the IOM Seafood Choices Report 18 published in 2007, that was devoted completely 19 to reviewing the literature, integrating the 20 literature, and making recommendations about 21 what people should do with regards to their 22 seafood choices, and what researchers should (202) 234-4433 Neal R. Gross & Co., Inc. Page 189 1 be concentrated on based on information that 2 still needs to be sorted out. 3 We also -- all of us know that the 4 FDA has issued a draft report that until 5 recently was available for public comment 6 where they are actually doing a quantitative 7 risk and benefit assessment of commercial fish 8 consumption based on the very interesting 9 issue that, on the one hand, fish consumption 10 has been associated with improvements in 11 neurological development in children and 12 reduction in risk of heart disease and stroke. 13 But on the other hand, methylmercury has been 14 associated with the opposite risk of slowing 15 down neurological development, and perhaps 16 risk for heart disease and stroke. 17 The two reports -- the IOM Report 18 and the FDA analysis are very much linked with 19 each other, because what the IOM Report did 20 was to endorse the 2004 recommendation or 21 advisory from the FDA and EPA with a caveat 22 that they could not do themselves a (202) 234-4433 Neal R. Gross & Co., Inc. Page 190 1 quantitative benefit risk assessment to answer 2 more precisely the question, and they 3 recommended for another agency to do so. And 4 that's why the FDA decided to take on this 5 task. 6 We had further contacts with the 7 FDA, and Mike Bolger, from their Risk 8 Assessment Unit, was kind enough to have 9 further conversations and a formal 10 presentation with our subcommittee for us to 11 further understand the methodology that they 12 used in their assessment, and where they were 13 going with it. 14 And the picture that is emerging 15 from reading these reports and having had 16 conversations with experts is that fish 17 consumption is, indeed, a healthy practice, 18 that it should be recommended, but that, at 19 the same time, the risk of methylmercury 20 contamination in fish is real, and the public 21 needs to be well informed, especially about 22 the fish species that are very high in (202) 234-4433 Neal R. Gross & Co., Inc. Page 191 1 methylmercury, and the amounts of fish that 2 would be safe to consume for different 3 segments of the population, with special 4 attention being paid to pregnant women and 5 young children. 6 In the U.S., the level of fish 7 consumption is quite low, and in terms of the 8 top fish species consumed, none of them are in 9 the high methylmercury category. 10 So the main concern right now 11 pretty much among all the experts and the 12 reports that we have read is pretty much 13 related to the concern that it seems that, as 14 a result of the 2004 advisory, a number of 15 groups took it upon themselves to recommend -- 16 for example, pregnant women, to don't eat fish 17 at all during pregnancy. 18 So this has really become an issue 19 as to how best to communicate the benefits, 20 the risks, and for people to be able to make 21 an informed decision. So we believe that that 22 is going to be the challenge for us as we (202) 234-4433 Neal R. Gross & Co., Inc. Page 192 1 write this section of our Dietary Guidelines 2 Advisory Committee chapter. 3 So what we are planning then is to 4 base our section on risk of fish consumption 5 based on the IOM Report. And if it's made 6 available to us in a more complete fashion, 7 perhaps take into account some of the findings 8 from the 2009 FDA Report. 9 And to do an NEL literature review 10 on the benefit risk analysis of fish 11 consumption, but starting in 2006, because the 12 IOM Report has actually summarized all the 13 literature until then. 14 We believe it's very important for 15 us to better understand how to make more 16 available to the public at large data on fish 17 species specific methylmercury content, so 18 that people can actually decided by themselves 19 and understand what are the different 20 methylmercury levels in different fish. 21 And we also want to better 22 understand the fish consumption patterns of (202) 234-4433 Neal R. Gross & Co., Inc. Page 193 1 different species of fish by socioeconomic, 2 demographic, and individuals with different 3 physiological status. 4 This is going to require 5 collaborating -- a collaboration between the 6 Food Safety Subcommittee and the Fatty Acid 7 Subcommittee. And I'm sure we will be soon 8 meeting to discuss how to go about it, because 9 the Fatty Acid Subcommittee, we understand, 10 will be addressing the benefits related to 11 fish consumption. 12 And now I will turn the 13 presentation to Roger, who will talk about new 14 food safety technology. 15 MEMBER CLEMENS: Thank you, 16 Rafael. 17 You should note, too, that it's 18 more, as Rafael spoke about methylmercury, is 19 more than just content of that in fish. We 20 want to be looking at some of the nutrients, 21 other nutrients found in fish that actually 22 may offset some of the negative impacts. (202) 234-4433 Neal R. Gross & Co., Inc. Page 194 1 Therefore, it's important that we conduct this 2 risk analysis and risk benefit analysis on the 3 fish. 4 Thank you, Rafael, very much for 5 that insight. 6 We looked at the data on new 7 technologies since our last meeting. Our 8 research thus far has not shown any 9 differences from what we reported last time, 10 so we will continue to explore other 11 opportunities and technologies that might be 12 available to ensure a safe management of food 13 supply in the home. 14 What we have learned, however, is 15 that we want to look more at this important 16 topic of food allergies. Clearly the topic of 17 food allergies has extended beyond the basic 18 eight. 19 Through the excellent work from 20 Kellie and her team, we've actually explored 21 some additional programs with a number of 22 agencies, one within CFSAN, and one under (202) 234-4433 Neal R. Gross & Co., Inc. Page 195 1 NIAID here in Washington. One deals with food 2 allergy, food allergy labeling, food allergy 3 implications from the food allergy labeling of 4 2002. 5 We're exploring that in terms of 6 regulatory, and has it made a difference in 7 food selection in the home, as well as for 8 commercial entities. 9 We should note that there will be 10 a public hearing on this topic later this 11 year. Don't know if that's going to make it 12 for the Dietary Guidelines, though. It may be 13 just too late for us to consider. But we want 14 to keep our eyes open to see where that lands 15 for us, Linda. 16 It was really quite intriguing. 17 We're very pleased that Katie was able to give 18 us some additional information. So we're 19 working with the folks in CFSAN to see if 20 there's additional behavioral and choice 21 information that we might be able to use in 22 terms of selection of foods that might be (202) 234-4433 Neal R. Gross & Co., Inc. Page 196 1 reducing our exposure to food allergens. 2 The work by Marshal Plaut, both at 3 NIAID, information that was shared in the last 4 conference call with our team, looking at what 5 issues there are in food allergy research, and 6 beyond just the basic eight. We're excited 7 about sharing some of the mechanisms, as well 8 as some of the food implications beyond the 9 basic eight -- how some of those guidelines 10 have actually transformed into clinical 11 practice so that, in fact, physicians and 12 health care providers are better informed 13 about food allergies. 14 Under -- oh, this is the 15 development of the piece I just shared with 16 you. So we're excited that we will be working 17 with the agency to explore this in greater 18 detail. And part of the greater detail, we 19 want to do additional evidence-based review, 20 and thank you very much for, Donna Kellie, for 21 initiating the kind of work that we see here 22 to look at the evidence and say, have we (202) 234-4433 Neal R. Gross & Co., Inc. Page 197 1 changed behaviors, have we changed the choice 2 of the food supply to reduce our exposure to 3 various food components? 4 As we indicated just moments ago, 5 that we're excited about seeing the public 6 comment period, and hopefully some of us will 7 be able to attend that comment period to 8 incorporate the data and perhaps our 9 Guidelines. 10 So at the end of the day, we 11 looked to invite some folks from NIAID, 12 perhaps we'll get Mike or Marshall on board 13 with this at one of our subcommittee meetings, 14 certainly at one of our conference calls, to 15 include what's going on, and see what we 16 actually include in our recommendations for 17 the future. 18 We're really quite excited about 19 this -- really -- that agencies working 20 together for a common issue. It goes back to 21 our priorities here. 22 Clearly the issues on food safety (202) 234-4433 Neal R. Gross & Co., Inc. Page 198 1 and behavior, we're looking at food safety 2 behaviors in the home. We're not here to look 3 at the food safety issues that we've all 4 experienced in the press of late. Keep that 5 in mind. 6 We clearly want to continue to 7 look at the risks and benefits of food fish 8 consumption, so we're working with Dr. 9 Pearson's group on food analysis on fish 10 consumption. 11 Then we'll continue to explore 12 food technologies. The food technologies that 13 might be incorporated into the home at nominal 14 expense. And of course, we'll hit the very 15 popular topic of food allergies. 16 That's it for here. 17 Any questions? 18 Shelly? 19 MEMBER NICKOLS-RICHARDSON: This 20 is Shelly Nickols-Richardson. Related to the 21 in-home food safety behaviors, it does relate 22 to what's been in the press lately that, in (202) 234-4433 Neal R. Gross & Co., Inc. Page 199 1 two different states, I've had extension 2 agents share with me that they have received 3 an increase in the number of phone calls 4 related to home canning and long-term storage 5 of food. 6 So not just sort of the short 7 term, are you getting the refrigerator 8 temperatures correct. I don't know how much 9 information there might be related to home 10 canning, long-term preservation of foods. 11 But it is a concern. And even if 12 it's not something that can be addressed in 13 the 2010 Guidelines, perhaps it's an emerging 14 issue for later. 15 MEMBER CLEMENS: Actually, we are 16 addressing that. Thank you for sharing that, 17 Shelly. 18 Rafael? 19 MEMBER PEREZ-ESCAMILLA: Yes, it's 20 in the PICO chart. 21 CHAIR VAN HORN: Tom, go ahead. 22 MEMBER PEARSON: Rafael, I had a (202) 234-4433 Neal R. Gross & Co., Inc. Page 200 1 question for you relative to the FightBAC!(c) 2 Program, so I was pleased you are going to 3 look at that and see. But I guess one of the 4 questions I had is whether or not you're going 5 to look at it relative to its evidence base 6 for effectiveness. And if not, when we could 7 really put in some of the same criteria that 8 we use for all of our other guidelines of what 9 class and grade of evidence we have that these 10 things work. 11 You know, we have the U.S. 12 Preventive Services Task Force. We have a 13 variety of things that are very, you know, 14 evidence oriented now, and this is such an 15 important area, this home food safety, that I 16 think it should be held to the same standards. 17 CHAIR VAN HORN: Larry? Oh, I'm 18 sorry. 19 MEMBER PEREZ-ESCAMILLA: The 20 answer is absolutely yes. 21 CHAIR VAN HORN: Larry? 22 MEMBER APPEL: Larry Appel. I (202) 234-4433 Neal R. Gross & Co., Inc. Page 201 1 wanted to find out if there's sort of a 2 question that comes before these, because it 3 looks like these are focusing on sort of 4 things that we think are important. 5 But I was wondering is, you know, 6 is there any sort of compilation of, you know, 7 where is the problem here? You know, is it, 8 you know, is it gastroenteritis? Is it 9 hemolytic-uremic syndrome from undercooked 10 meat? 11 I mean, so that you actually then 12 target, you know, your questions to the big 13 public health problems. I mean that's what we 14 do on these other committees. You know, like 15 what effects blood pressure? What effects 16 heart disease? 17 And I see a different sort of 18 structure here, sort of like topical rather 19 than top down where is the problem. So I just 20 -- is there some data that should guide us? 21 I'm just sort of curious. 22 MEMBER PEREZ-ESCAMILLA: Yes, (202) 234-4433 Neal R. Gross & Co., Inc. Page 202 1 unfortunately, the surveillance of home-based 2 food illness outbreaks is not great for a 3 number of issues -- the nature of them plus, 4 you know, I guess the word is the lack of 5 investment in terms of trying to answer -- to 6 put the resources to answer your question. 7 There are some attempts at trying 8 to actually quantify the home-based outbreaks, 9 and what are the causes of them. But it's not 10 at the same level, I think, as it is for other 11 topics that are being addressed by the 12 Committee, unfortunately. 13 But we will -- if that literature 14 exists, if any evidence is out there, we will 15 find it. 16 MEMBER APPEL: Okay. Let me 17 follow up then. Maybe, you know, the preface 18 to each of these should be, how big is the 19 problem. So I was listening to your comments 20 about methylmercury, you know, so how big is 21 that problem, you know, so that we can sort of 22 put the recommendations in the context. And (202) 234-4433 Neal R. Gross & Co., Inc. Page 203 1 you know, that may be more of a comment than a 2 question. 3 MEMBER CLEMENS: We actually -- 4 thank you for the questions on that, Larry -- 5 we are actually examining the methylmercury 6 implications, as well as the other issues to 7 which Rafael referred. If some of those 8 things pop up, then we will pursue on the 9 clinical basis, or any other of the health 10 consequences through the CDC and other 11 resources. 12 CHAIR VAN HORN: Cheryl? 13 MEMBER PEREZ-ESCAMILLA: And I 14 just want to follow up on that because, in 15 terms of the methylmercury issue, one big 16 concern in OB/GYNs telling pregnant women to 17 don't eat fish during pregnancy. Nobody has 18 ever made that recommendation. It seems that 19 the evidence will not support at all making 20 that recommendation. 21 So your point is very well taken 22 that we need to have a better estimate of -- (202) 234-4433 Neal R. Gross & Co., Inc. Page 204 1 within the context of the U.S., how big is the 2 problem, yes. 3 MEMBER ACHTERBERG: This is Cheryl 4 Achterberg. An entirely different kind of 5 question, different subject area. 6 But in the Nutrient Adequacy 7 Subcommittee, one of the issues that we talked 8 about that probably needed to be examined -- 9 and I'm not sure this is the best phrasing yet 10 for it -- but with the new interest or larger 11 interest now in organic foods, local foods and 12 such, that it felt like some subcommittee 13 needed to look at the implications there. 14 And I don't know if you were aware 15 that your subcommittee was nominated to do 16 that. 17 (Laughter.) 18 MEMBER CLEMENS: Thank you very 19 much, Cheryl. You may recall that, in the 20 first meeting we had, that we addressed the 21 "O" word. And it was agreed at that time 22 maybe we wouldn't address it. (202) 234-4433 Neal R. Gross & Co., Inc. Page 205 1 But it sounds like from your group 2 that perhaps we should put it back on our 3 plate. And they also came up with that wild - 4 - on the fish side, wild versus farmed. And 5 we actually -- that is one of our PICO 6 questions. 7 So we'd be glad to embrace that 8 new question and put it back on. Thank you 9 very much, Cheryl. 10 MEMBER NELSON: Well, I -- this is 11 Mim -- I respectfully may disagree, because 12 I'm not sure -- there are so many different -- 13 I mean there's local, there's organic -- I'm 14 not sure that -- I'm sorry that, you know, Dr. 15 Hamm just left. 16 But I'm not sure that -- I'm 17 concerned that, if we deal with it from a 18 food -- in the food safety section, that 19 somehow, just by default, that then there's 20 some kind of worry and question about, you 21 know, local food, and organic food, and all 22 this other stuff which -- I mean we just have (202) 234-4433 Neal R. Gross & Co., Inc. Page 206 1 a whole range of the food supply. 2 And I think that dealing with the 3 home is the right way to go with it. And I 4 think -- I'm just -- I think it may be the 5 wrong approach for putting organic -- I mean, 6 what's the question? 7 If there's a question about local 8 foods, sustainable foods, organic foods 9 around, you know, nutrient quality, that's 10 another question. 11 But if there is really a serious 12 concern about organic foods, which I don't 13 know the safety literature as much, but I 14 don't think there is, because it's being 15 dealt with elsewhere. 16 As you said, it's about the home 17 that you guys are dealing with. I guess I 18 would just opt for that's the right -- we've 19 got a lot of work to do, and that would be 20 the way to go. But -- 21 MEMBER CLEMENS: Where does the 22 local fit? What bucket should it fit in? We (202) 234-4433 Neal R. Gross & Co., Inc. Page 207 1 do know that the local farms -- there's 2 guidelines at the USDA that indicate there 3 are some farms, some volumes that, in fact, 4 do not fall under the FDA/USDA guidelines for 5 food safety. And maybe we have an 6 opportunity to educate the consumers about 7 these kinds of issues. 8 And the question I was going to 9 give to Dr. Hamm was, in fact, what measures 10 are the local farmers using to be sure that 11 the food supply is safe? There aren't any 12 guidelines right now. 13 MEMBER ACHTERBERG: And to follow 14 up on Mim's comments, I think in our 15 subcommittee we were well aware of some of 16 the issues raised, Mim. Part of it, frankly, 17 is a workload issue, as this particular 18 subcommittee has so many questions to sort 19 through. 20 So we recognize that there are 21 issues around this that perhaps go beyond the 22 traditional food safety perspective, but that (202) 234-4433 Neal R. Gross & Co., Inc. Page 208 1 there's also an opportunity here, even if 2 it's very brief, to correct some 3 misconceptions, and that a function of the 4 Dietary Guidelines might be to do just that. 5 CHAIR VAN HORN: Right. And any 6 of the speakers that we had already, and 7 including those tomorrow, have agreed, you 8 know, that if we have follow-up issues, 9 follow-up questions, we can certainly go to 10 them. 11 Chris? 12 MEMBER WILLIAMS: Chris Williams. 13 It looks like you're trying to categorize 14 things in terms of foodborne illness, and 15 then food contaminants, which mercury would 16 be one. 17 Have you considered other 18 contaminants, such as pesticides and other 19 things that could contaminate the foods? 20 MEMBER PEREZ-ESCAMILLA: Yes, 21 specifically with regards to fish, that is a 22 very important question. Over 75 percent of (202) 234-4433 Neal R. Gross & Co., Inc. Page 209 1 the fish advisories, local and federal and so 2 on, are related to methylmercury in fish. 3 Some of the experts that we have 4 contacted believe, or their data suggests to 5 them that, for example, persistent organic 6 pollutants, the POPs, are not a big issue in 7 the U.S., that if methylmercury is addressed, 8 essentially that would address the biggest 9 concern. 10 Others, essentially their concern 11 is related to how complex the data is. So 12 the combination of perhaps having more data 13 available for methylmercury, and that it 14 appears that it is a much larger problem than 15 other known contaminants, lead us to choose 16 this path of concentrating mostly on the 17 methylmercury in fish. 18 If your question is about 19 contaminants in general for all sorts of 20 foods, pesticides and so on, we've had some 21 conversations as to how this probably would 22 fall within the jurisdiction of EPA, and (202) 234-4433 Neal R. Gross & Co., Inc. Page 210 1 we're not sure how far we would be able to 2 get if we took that path. But any comments 3 are more than welcome, because it is an 4 important issue. 5 MEMBER RIMM: Yes, this is Eric 6 Rimm. 7 I do worry about dropping 8 pesticides from the list for fish, because I 9 think if you ask anybody in this room, would 10 you rather have wild salmon or farmed salmon, 11 I know you just said it's on your PICO chart, 12 everybody would say, wild, likely. And the 13 reason is because they're worried about 14 pesticides in the feed in the farmed salmon. 15 So you know, while I believe that 16 I would have salmon of either kind, because I 17 think it's going to have plenty of omega-3 18 fatty acids, and that's what I'm concerned 19 about, I think you may run into the same 20 problem with pregnant women who are trying to 21 decide whether to eat fish or not based on 22 the mercury content. (202) 234-4433 Neal R. Gross & Co., Inc. Page 211 1 Salmon has no mercury, but there 2 might be a difference in persistent 3 pesticides. So if the perception is out 4 there, I think we should address it either 5 way. 6 MEMBER PEREZ-ESCAMILLA: And the 7 response from the FDA related to POPs and 8 dioxin, dioxin-like compounds in farmed 9 salmon, which the concern is through the feed 10 -- 11 MEMBER RIMM: Yes. 12 MEMBER PEREZ-ESCAMILLA: -- that 13 almost -- that evidence came from studies 14 done outside the U.S. And that, as far as 15 they know, it is not an issue for farmed 16 salmon in the U.S. 17 MEMBER RIMM: Well, yes, but 18 three-quarters of the salmon -- 19 MEMBER PEREZ-ESCAMILLA: Or Chile. 20 MEMBER RIMM: All the salmon comes 21 from Chile. 22 MEMBER PEREZ-ESCAMILLA: So I will (202) 234-4433 Neal R. Gross & Co., Inc. Page 212 1 qualify my statement. So they said the U.S. 2 or the suppliers for salmon in the U.S., such 3 as Chile. 4 So according to their data, the 5 evidence related to farmed salmon and dioxin, 6 it does not apply to the situation in the 7 U.S. 8 MEMBER RIMM: I mean, with all due 9 respect, I disagree, because there are data - 10 - 11 MEMBER PEREZ-ESCAMILLA: Okay. 12 MEMBER RIMM: -- that suggest that 13 there's quite a distribution of it. And 14 again, I don't think there's -- I know there 15 are studies showing that if pregnant women 16 have substantial amounts of pesticides, that 17 there is neurological effects in their 18 children. 19 It's not generally from fish. 20 It's usually from eating other foods that are 21 very high in pesticides. But the perception 22 is out there, I think, that people choose (202) 234-4433 Neal R. Gross & Co., Inc. Page 213 1 wild over farmed because of this perception 2 of pesticides. 3 And there are plenty of studies, 4 and there have been many over the last five 5 years sort of monitoring differences in 6 pesticides between fish from Chile, and from 7 Scotland, and from Canada, and from the U.S., 8 and there are differences. 9 You know, whether there are 10 important health differences related to that, 11 I don't know. But I think -- I'm sure that 12 it wouldn’t come up if we just focus on 13 mercury, because mercury doesn't -- mercury 14 is not part of anything -- any fish like 15 salmon or any of the smaller species. 16 Mercury is mostly for tuna, and shark, and 17 swordfish. 18 So I just worry that we're sort of 19 missing out on a whole half of the 20 misperception related to fish consumption by 21 just focusing on mercury. 22 CHAIR VAN HORN: All right. Well, (202) 234-4433 Neal R. Gross & Co., Inc. Page 214 1 excellent points, and outstanding 2 presentations. I think we've all learned a 3 lot today. 4 And certainly appreciate the time 5 and energy that our guest speakers took, as 6 well as all of the groups that came bright 7 and early this morning to begin really 8 hashing through some of these issues. 9 So we will now adjourn for the 10 day, and plan to reconvene tomorrow morning 11 bright and early at 8:30 with another couple 12 of presentations, and then continue with our 13 scientific reports. 14 Thank you all for coming. 15 (Whereupon, the above-entitled 16 matter was adjourned at 5:11 p.m.)