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Efficacy of Nasojejunal Enteral Feeding in Critically Ill Patients.

This study has been completed.
Sponsor:
Information provided by:
Melbourne Health
ClinicalTrials.gov Identifier:
NCT00256048
First received: November 17, 2005
Last updated: February 3, 2009
Last verified: February 2009
History of Changes

November 17, 2005
February 3, 2009
May 2003
 
Efficacy of feeding [ Time Frame: participants will be followed until death, discharge from ICU, commencement of oral or parental nutrition or 28 days post ICU admission ]
Same as current
Complete list of historical versions of study NCT00256048 on ClinicalTrials.gov Archive Site
  • 1. To determine the incidence of complications with enteral feeding via nasogastric and nasojejunal routes. [ Time Frame: participants will be followed until death, discharge from ICU, commencement of parental or oral nutrition or 28 days post ICU admission. ]
  • 2. To assess the efficacy of current strategies for optimising enteral feeding efficacy. [ Time Frame: participants will be followed until death, discharge from ICU commencement of oral or parental nutrition,or 28 days post ICU admission. ]
  • 1. To determine the incidence of complications with enteral feeding via nasogastric and nasojejunal routes.
  • 2. To assess the efficacy of current strategies for optimising enteral feeding efficacy.
 
 
 
Efficacy of Nasojejunal Enteral Feeding in Critically Ill Patients.
Efficacy of Nasojejunal Enteral Feeding in Critically Ill Patients.

The purpose of this study is to determine if naso-jejunal feeding (feeding beyond the stomach) improves the efficacy of enteral feeding (feeding into the gut) in critically ill patients.

The study hypothesis is that in patients who fail to establish enteral feeding via the nasogastric route, introduction of nasojejunal feeding will lead to more effective enteral feeding than the current regime involving staged introduction of promotility agents.

The study examines the area of enteral feeding in critically ill patients. Current standard enteral feeding practice is via a nasogastric with the addition of promotility agents for patients who fail to absorb their enteral nutrition.

This study compares the efficacy of nasojejunal feeding feeding with nasogastric enteral feeding with the addition of promotility agents.

The duration of feeding will be determined by the patients nutritional requirements and their general condition. However the data will be collected for duration of enteral feeding, 28 days or ICU discharge whichever occurs first.
Interventional
 
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Intensive Care Patients Requiring Enteral Feeding.
Procedure: Nasojejunal feeding
 
 

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
50
July 2005
 

Inclusion Criteria:

  1. Adult patients (18years or over) admitted to the ICU with an expected stay of more than 48 hours.
  2. Patients commenced on enteral feeding via a nasogastric tube who fail to tolerate gastric feeding due to excessive gastric aspirate volumes.

  3. Patients who consent or if the patient is incompetent, the next of kin, who consent, to inclusion in the study.

    -

Exclusion Criteria:

  1. patients less than 18 years of age.
  2. Patients with known allergy to promotility agents, metoclopramide or erythromycin.
  3. Patients with a contra indication to nasojejunal feeding. -
Both
18 Years and older
No
Contact information is only displayed when the study is recruiting subjects
Australia
 
NCT00256048
2002.228
No
Melbourne Health
Melbourne Health
 
Principal Investigator: Megan Robertson Intensive Care Unit, Royal Melbourne Hospital
Melbourne Health
February 2009

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP