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Intramural Research Awards

  • Updated: 08/14/2012

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Tom Misteli Wins Arthur S. Flemming Award

Tom Misteli, head of the Cell Biology of Genomes Group in NCI's Laboratory of Receptor Biology and Gene Expression, has won a 2011 Arthur S. Flemming Award. Misteli’s laboratory studies the cell biology of genomes. Defects in genome organization and nuclear architecture are responsible for numerous human diseases including cancer, neurodegenerative disorders, and muscular dystrophies, and they recently have been linked to human aging. Misteli’s lab uses molecular techniques in conjunction with live-cell microscopy to understand how genomes are organized in intact cells and how the spatial organization of genomes contributes to their function. The lab uses several differentiation and disease models, including embryonic and adult stem cells, to elucidate how genome organization contributes to physiological processes and disease, particularly cancer and aging. See his February 2011 article in Scientific American, which created his illustration.

Established by the Downtown Jaycees in 1948, the Flemming Awards honor outstanding federal employees. Winners are selected from all areas of the federal service. The awards were established in honor of Arthur Flemming’s commitment to public service throughout his distinguished career, which spanned seven decades and 11 presidencies.


Three NIHers Among PECASE Winners

In July 2012, President Obama named 96 researchers as recipients of the Presidential Early Career Awards for Scientists and Engineers (PECASE), the highest honor bestowed by the United States Government on science and engineering professionals in the early stages of their independent research careers. Among them were three researchers from the NIH intramural research program: Peter Crompton of NIAID, for his studies on the mechanisms of naturally-acquired immunity to malaria; Daniel Larson of NCI, for his studies on transcription dynamics of single human cells; and Justin Taraska of NHLBI, for his studies on the architecture and control of vesicle fusion in excitable cells. The awardees visited the White House on July 31 for a ceremony and group shot with the President, followed by a local reception at the NIH on August 1.