Day 1 - October 9, 2012 |
Introduction and Background |
8:30 a.m. |
Introduction—Opening Remarks |
8:55 a.m. |
Broad Overview of the Meeting and the State of the Science:
- Incidence, Prevalence, and Bi-directionality of the Diabetes and Depression Association
- Public Health Impact of Co-morbid Diabetes and Depression
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Session 1: Mechanisms Linking Diabetes and Depression Session Chairs: Irwin Lucki, Ph.D., and Sherita Golden, M.D., M.H.S |
9:25 a.m. |
Introduction to Session 1
Neuroendocrine Factors
HYPOTHALAMIC-PITUITARY-ADRENAL AXIS |
9:40 a.m. |
Neuroplasticity Related to the HPA Axis and Cognitive Deficits in Animal Models of Diabetes as a Source of Depression Comorbidity |
10:00 a.m. |
Evidence of HPA Axis Dysfunction in Depression and Diabetes in Clinical and Population-based Studies |
10:15 a.m. |
Depression and Risk of Cognitive Decline in Diabetes—Evidence From Human Studies |
10:30 a.m. |
Question-and-Answer Session |
10:50 a.m. |
BREAK
CIRCADIAN RYTHMS AND SLEEP DISTURBANCE |
11:10 a.m. |
The Role of Circadian Rhythms in Regulating Metabolism—Basic Science Mechanisms |
11:25 a.m. |
Effects of Sleep Disturbances on Metabolic Function, Diabetes Risk, and Depression |
11:40 a.m. |
Question-and-Answer Session |
12:00 p.m. |
LUNCH ̶ Boxed Lunch With Advance Purchase
Downstream Biological Factors
INFLAMMATION |
1:00 p.m. |
Animal Models of the Immunological Challenge as a Bridge Between Depression and Diabetes |
1:15 p.m. |
Evidence of Inflammation in the Pathophysiology of Depression and Diabetes in Human Studies |
1:30 p.m. |
Question-and-Answer Session
BEHAVIORAL, PSYCHOSOCIAL, AND ENVIRONMENTAL FACTORS |
2:05 p.m. |
Contextual Factors in Diabetes and Depression |
2:25 p.m. |
Diabetes Distress Versus Depression: Implications for Glycemic Control |
2:40 p.m. |
Adherence to Diabetes Self-care Behaviors in Depression |
2:55 p.m. |
Depression in Children with Diabetes |
3:10 p.m. |
Question-and-Answer Session |
3:30 p.m. |
BREAK
TREATMENT FACTORS |
3:45 p.m. |
Antipsychotic/Antidepressants in Animal Models of Diabetes |
4:00 p.m. |
Association of Antidepressant and Antipsychotic Treatments With Obesity and Incident Diabetes in Population-based Studies
Question-and-Answer Session |
4:20 p.m. |
Panel Discussion: What Are the Crucial Unanswered Research Questions? |
5:20 p.m. |
Wrap-up and Logistics for Day 2 |
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Day 2 - October 10, 2012 |
8:00 a.m. |
Welcome Back and Orientation to the Day’s Schedule |
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Session 2: Treatment Session Chair: Wayne Katon, M.D. |
8:10 a.m. |
Introduction to Session 2 |
8:25 a.m. |
Evidenced-based Depression Treatments for Treating Patients With Co-morbity: Effects on Depression and Diabetes Outcomes |
8:45 a.m. |
Question-and-Answer Session |
9:00 a.m. |
Improving Depression Outcomes in Large Populations of Patients With Diabetes |
9:20 a.m. |
Question-and-Answer Session |
9:35 a.m. |
Multi-condition Collaborative Care for Both Depression and Diabetes |
9:55 a.m. |
Question-and-Answer Session |
10:10 a.m. |
BREAK |
10:30 a.m. |
Effect of Improving Diabetes Disease Control in Large Populations of Patients With Diabetes on Psychological Distress and Well-being |
10:50 a.m. |
Question-and-Answer Session |
11:05 a.m. |
Improving Depressive Symptoms and HbA1C Outcomes in Patients With Type I Diabetes |
11:25 a.m. |
Question-and-Answer Session |
11:40 a.m. |
Panel Discussion: What are the Crucial Unanswered Research Questions? |
12:15 p.m. |
LUNCH ̶ Boxed Lunch With Advance Purchase |
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Session 3: Prevention and Public Health Session Chair: Richard Holt, M.A., M.B., B.Chir., Ph.D., F.R.C.P., F.H.E.A. |
1:15 p.m. |
Introduction to Session 3 |
1:30 p.m. |
Prevention of Diabetes in Those With Depression; Findings From the Major Diabetes Prevention Trials |
1:50 p.m. |
Question-and-Answer Session |
2:05 p.m. |
Prevention of Depression in Those With Diabetes |
2:25 p.m. |
Question-and-Answer Session | |
2:40 p.m. |
BREAK |
3:00 p.m. |
Roundtable: Dissemination, Implementation, and Public Health Panel |
4:30 p.m. |
Concluding Remarks |