Contact Details

Barbara Rehermann, MD
Chief, Immunology Section
Liver Diseases Branch
NIDDK, NIH
10 Center Drive
Bldg. 10, Room 9B16
Bethesda, MD 208927

Ph: 301-402-7144
Fax: 301-402-0491
Rehermann@nih.gov

Immunology Section

Barbara Rehermann, M.D. Lab Members
Current Projects Lab Alumni
Recent Publications  


Intracellular innate immune response to hepatitis C virus. Hepatocytes sense double-stranded RNA (dsRNA) via the cytoplasmic pattern recognition receptor RIG-I and the endosomal pattern recognition receptor TLR3. Secreted IFN-b induces an antiviral state in neighboring uninfected cells via JAK/STAT-mediated signaling. HCV interferes with this pathway at multiple points (for a review see J Clin Invest 119:1745-54).
See more photos

The Immunology Section of the Liver Diseases Branch is headed by Dr. Barbara Rehermann. The research aims of the section include:

  1. Innate and adaptive immune responses to viral infections of humans, in particular hepatitis B and C virus infections.
  2. Immunobiology of the liver and liver cancer.
  3. Memory T and B cell responses to vaccination.

Page last updated: December 08, 2011

General inquiries may be addressed to:
Office of Communications & Public Liaison
NIDDK, NIH
Bldg 31, Rm 9A06
31 Center Drive, MSC 2560
Bethesda, MD 20892-2560
USA
301.496.3583

The National Institutes of Health   Department of Health and Human Services   USA.gov is the U.S. government's official web portal to all federal, state, and local government web resources and services.  This website is certified by Health On the Net Foundation. Click to verify.