Use of Acupuncture In Children With Autistic Spectrum Disorder

This study has been completed.
Sponsor:
Information provided by:
The University of Hong Kong
ClinicalTrials.gov Identifier:
NCT00352352
First received: July 13, 2006
Last updated: NA
Last verified: July 1999
History: No changes posted

July 13, 2006
July 13, 2006
 
 
  • Ritvo-Freeman Real Life Scale (RFRLS) was conducted on both groups before (Week 0) and after (Week 8) acupuncture.
  • Functional Independence Measure for children (WeeFIM) consists of 18 questions concerning on the Functional Independence Measure for children, which was conducted on both groups before (Week 0) and after (Week 8) acupuncture.
  • Parental Stress Index (PSI) consists of child domain, parent domain and a total domain, which was conducted on both groups before (Week 0) and after (Week 8) acupuncture.
  • Clinical Global Impression Scale (CGIS) is a measure in a Likert scale of 0 – 7, which was conducted on both groups before (Week 0) and after (Week 8) acupuncture.
Same as current
No Changes Posted
 
 
 
 
 
Use of Acupuncture In Children With Autistic Spectrum Disorder
Randomized Control Trial of Using Acupuncture In Children With Autistic Spectrum Disorder

This is a study of the efficacy of acupuncture in children with autism.

Autism Spectrum Disorder (ASD) or autism is a neurodevelopmental disorder with unknown etiology. ASD consisted of 3 core features: 1) disorder of language or communication; 2) disorder of social interaction; and 3) obsessive and stereotypic behavior.

Acupuncture had been practiced in China for over two millennia. In Traditional Chinese Acupuncture, nearly 400 acupoints on the body surface are interrelated to various functions. The approach in TCM, in sharp contrast to western medical concept, was a “holistic” approach with a philosophical background of balancing the “Yin-and-Yang”. The main objective of TCM was to improve health of body and mind by deblocking the flow of “Qi” in the body. The pathophysiological basis of TCM aimed to improve “energy” or “body-flow” or “Qi” [“de-qui” in Chinese]. The effect of acupuncture was had been proven in animal and human studies to be due to direct neural stimulation, changes in neurotransmitters such as endorphin, immunological markers or endocrinological signals. Thus, acupuncture is especially effective in chronic disorders, especially neurological ones.

As there is no TCM concept of mental retardation or autism, we propose that ASD is part of the spectrum of the TCM concept of the “Four Delayed Syndrome” in children with “delay in motor skills, speech, hair and teeth eruption” according to TCM concept. Thus, we approach ASD according to TCM concept as part of the lower intelligence due to imbalance of “Heart meridian and Kidney meridian” (i.e. yin-yang imbalance) resulting in communication problem and “Liver meridian” (yin-yang imbalance) leading to behavioral problems.

Our objective is to use a different approach in looking at ASD and to assess the efficacy of TCM model in improving the functional status of these children. Specific acupoints corresponding to various organs and meridians were used for ASD. The organ and meridian concept in TCM model has been as a fundamental basis to improve the behavior, cognition and communicative ability in children with ASD.

Interventional
Phase 3
Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind
Primary Purpose: Treatment
  • Autism
  • Autistic Disorder
Procedure: Tongue Acupuncture (Procedure)
 
 

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
30
 
 

Inclusion Criteria:

  • The diagnosis of ASD or autism was made according to the criteria of the 4th edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) and Autism Diagnostic Interview-Revised (ADI-R).
  • The diagnosis of autism was made if it satisfied a score greater than 30 in the Childhood Autism Rating Scale (CARS).

Exclusion Criteria:

  • Children with associated neurological disorders such as Tuberous Sclerosis, Fragile X Syndrome and epilepsy.
Both
3 Years to 15 Years
No
Contact information is only displayed when the study is recruiting subjects
Hong Kong
 
NCT00352352
3469296479554546
 
 
The University of Hong Kong
 
Principal Investigator: Wong Virginia The University of Hong Kong
The University of Hong Kong
July 1999

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP