Comparison of Cardiac Computed Tomography for the Detection of Coronary Artery Disease With Nuclear Stress Test
Recruitment status was Recruiting
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| First Received Date ICMJE | July 14, 2006 | ||||||||
| Last Updated Date | January 14, 2009 | ||||||||
| Start Date ICMJE | March 2006 | ||||||||
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| Change History | Complete list of historical versions of study NCT00352937 on ClinicalTrials.gov Archive Site | ||||||||
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| Descriptive Information | |||||||||
| Brief Title ICMJE | Comparison of Cardiac Computed Tomography for the Detection of Coronary Artery Disease With Nuclear Stress Test | ||||||||
| Official Title ICMJE | Comparison of Cardiac Computed Tomography for the Detection of Coronary Artery Disease With Nuclear Stress Test | ||||||||
| Brief Summary | To compare the efficacy of 16-row multi-detector CT (MDCT) with standard myocardial perfusion imaging in detecting coronary artery disease (CAD) in patients without a previously established diagnosis of CAD. |
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| Detailed Description | Nuclear stress testing is currently the established non-invasive modality in detecting flow-obstructing coronary artery disease (CAD). Recently, multi-detector CT (MDCT) has emerged as a new modality that offers a non-invasive means to directly visualize coronary anatomy and any CAD. Studies have shown that MDCT has excellent sensitivity and a high negative predictive value in detecting significant CAD. The purpose of this study is to compare MDCT with nuclear stress testing for detecting CAD in previously undiagnosed patients. |
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| Study Type ICMJE | Observational | ||||||||
| Study Design ICMJE | Observational Model: Cohort Time Perspective: Prospective |
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| Biospecimen | |||||||||
| Sampling Method | Non-Probability Sample | ||||||||
| Study Population | All patients without prior CAD referred for nuclear stress testing |
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| Condition ICMJE | Coronary Arteriosclerosis | ||||||||
| Intervention ICMJE | |||||||||
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| Publications * | |||||||||
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* Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline. |
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| Recruitment Information | |||||||||
| Recruitment Status ICMJE | Recruiting | ||||||||
| Estimated Enrollment ICMJE | 100 | ||||||||
| Estimated Completion Date | December 2009 | ||||||||
| Primary Completion Date | |||||||||
| Eligibility Criteria ICMJE | Inclusion Criteria:
Exclusion Criteria:
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| Gender | Both | ||||||||
| Ages | 18 Years and older | ||||||||
| Accepts Healthy Volunteers | No | ||||||||
| Contacts ICMJE |
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| Location Countries ICMJE | United States | ||||||||
| Administrative Information | |||||||||
| NCT Number ICMJE | NCT00352937 | ||||||||
| Other Study ID Numbers ICMJE | 1124528 | ||||||||
| Has Data Monitoring Committee | Yes | ||||||||
| Responsible Party | Wen-Chih Wu, MD, Providence VA Medical Center | ||||||||
| Study Sponsor ICMJE | Providence VA Medical Center | ||||||||
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| Information Provided By | Providence VA Medical Center | ||||||||
| Verification Date | January 2009 | ||||||||
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ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP |
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