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eculizumab
A human monoclonal antibody directed against terminal complement protein C5. Eculizumab binds to terminal complement protein C5, thereby blocking C5 cleavage into pro-inflammatory components and blocking the complement-mediated destruction of paroxysmal nocturnal hemoglobinuria (PNH) red blood cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | Alexion monoclonal antibody 5G1.1 monoclonal antibody anti-C5 | |
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| US brand name: | | Soliris | |
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| Abbreviation: | | h5G1.1 | |
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