Testing Objective Methods for Template Matching Ventricular Tachycardia and Pacemapping
Recruitment status was Recruiting
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Patients sometimes suffer from life-threatening abnormal heart racing that originates from the lower chamber of the heart. These patients will often need an implantable defibrillator which has the ability to shock the heart back to a normal heart rhythm, but this does not prevent them from getting frequent recurrences of the bad heart rhythm needing shocks from the device. This can be painful and potentially harmful. Medicines to prevent recurrences of shocks are not very effective and have many side effects. An alternative to medicines for this is a procedure called a catheter ablation in which a wire is passed up through the blood vessels of the leg into the heart and used to find the short circuits which cause the dangerous heart rhythm. When the spot causing the trouble is found, the investigators can burn it ("ablate" it). This procedure is challenging and methods are needed to make it more effective and easier to do. One of the main ways for finding the short circuits involves using the electrocardiogram (the "ECG"). The regular ECG is simplistic and only makes use of recordings from 10 sites (6 precordial sites and 4 sites on both upper and lower limbs) on the body surface. The investigators are testing whether making recordings from 120 sites on the chest and back and using special computerized analysis of the recordings can help make catheter ablation for dangerous heart rhythms more effective.
Condition |
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Ventricular Tachycardia |
Study Type: | Observational |
Study Design: | Observational Model: Cohort Time Perspective: Prospective |
Official Title: | Quantitative Measurements Comparing Body Surface Potentials During Pacemapping and Spontaneous Ventricular Tachycardia |
- Correlating the arithmetic markers (CORR and MAD) to the distance between the pacing site and origin of the ventricular tachycardia or the index pacing site. [ Time Frame: One year ] [ Designated as safety issue: No ]
Estimated Enrollment: | 20 |
Study Start Date: | July 2010 |
Estimated Study Completion Date: | July 2011 |
Estimated Primary Completion Date: | July 2011 (Final data collection date for primary outcome measure) |
Groups/Cohorts |
---|
focal VT . |
Scar related VT, exit not identified |
Scar related VT exit identified |
Supreventricular tachycardia |
Show Detailed Description
Ages Eligible for Study: | 18 Years to 80 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Sampling Method: | Non-Probability Sample |
Patients will be recruited from consecutive patients referred for ablation of sustained ventricular tachycardia with or without structural heart disease or Patients referred for ablation of supraventricular tachycardia to the QEII Health Sciences Centre, in Halifax, NS.
Inclusion Criteria:
- All patients presenting with sustained monomorphic VT who are amenable to VT ablation.
- Patients referred for ablation of supraventricular tachycardia.
Exclusion Criteria:
- Patients presenting with ventricular tachycardia if no sustained tachycardia can be induced, or if in that particular patient pace-mapping is known to be an inaccurate method of mapping (e.g. in bundle branch reentry VT or fascicular VT).
Canada, Nova Scotia | |
Capital District Health Authority | Recruiting |
Halifax, Nova Scotia, Canada, B3H 3A7 | |
Contact: John Sapp, MD FRCPC 473 4272 john.sapp@cdha.nshealth.ca | |
Principal Investigator: John A Sapp, MD, FRCPC | |
Sub-Investigator: Ahmed El-Damaty, MD MSc |
Principal Investigator: | John A Sapp, MD, FRCPC | Capital District Health Authority, Canada |
Publications:
Responsible Party: | Dr John Sapp, Capital District Health Authority |
ClinicalTrials.gov Identifier: | NCT01170416 History of Changes |
Other Study ID Numbers: | SP12 |
Study First Received: | July 25, 2010 |
Last Updated: | June 21, 2011 |
Health Authority: | Canada: Ethics Review Committee |
Keywords provided by Capital District Health Authority, Canada:
Ventricular Tachycardia Body Surface Mapping |
Additional relevant MeSH terms:
Tachycardia Tachycardia, Ventricular Arrhythmias, Cardiac |
Heart Diseases Cardiovascular Diseases Pathologic Processes |
ClinicalTrials.gov processed this record on October 17, 2012