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Assessment of Retinal Nerve Fibre Layer by Optical Coherence Tomography in Uveitis Patients With Papilloedema

This study has been completed.
Sponsor:
Information provided by:
St. Franziskus Hospital
ClinicalTrials.gov Identifier:
NCT01170481
First received: July 21, 2010
Last updated: July 19, 2011
Last verified: July 2011
History of Changes
  Purpose

Assessment of optic disc morphology can be difficult in patients with uveitis and papilloedema. Therefore different optical coherence tomography (OCT) and laser scanning techniques may help to detect damage to the retinal nerve fibre layer.


Condition
Uveitis
Glaucoma

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Retinal Nerve Fibre Layer in Uveitic Secondary Glaucoma

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by St. Franziskus Hospital:

Primary Outcome Measures:
  • Alterations of retinal nerve fibre layer by optical coherence tomography [ Time Frame: once at study entry ] [ Designated as safety issue: No ]
    Baseline comparision of retinal nerve fibre layer thickness in patients with uveitis and with or without papilloedema at study entry. No follow-up examination scheduled


Estimated Enrollment: 50
Study Start Date: July 2009
Study Completion Date: April 2011
Primary Completion Date: December 2010 (Final data collection date for primary outcome measure)
Groups/Cohorts
papilloedema without glaucoma
papilloedema with glaucoma
glaucoma without papilloedema

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

all patients with anterior or intermediate uveitis and papillooedema in fluoreszein angiography.

Criteria

Inclusion Criteria:

  • anterior or intermediate uveitis
  • papilloedema
  • glaucoma

Exclusion Criteria:

  • dense cataract
  • dense vitreous opacification
  • circular posterior synechiae
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01170481

Locations
Germany
Department of Ophthalmology at St.-Franziskus Hospital
Muenster, Germany, 48145
Sponsors and Collaborators
St. Franziskus Hospital
Investigators
Study Chair: Arnd Heiligenhaus, MD Department at St. Franziskus Hospital
  More Information

Additional Information:
Related Info  This link exits the ClinicalTrials.gov site

No publications provided

Responsible Party: Arnd Heiligenhaus M.D., Department of Ophthalmology at St.-Franziskus Hospital Muenster
ClinicalTrials.gov Identifier: NCT01170481     History of Changes
Other Study ID Numbers: 2008-128-f-S
Study First Received: July 21, 2010
Last Updated: July 19, 2011
Health Authority: Germany: Ethics Commission

Keywords provided by St. Franziskus Hospital:
anterior and intermediate uveitis
papilloedema

Additional relevant MeSH terms:
Glaucoma
Papilledema
Uveitis
Ocular Hypertension
Eye Diseases
 Optic Nerve Diseases
Cranial Nerve Diseases
Nervous System Diseases
Uveal Diseases

ClinicalTrials.gov processed this record on October 17, 2012