Expression of S100A2 and Trefoil Factor Family Members in Epstein-Barr Virus Related Gastric Cancer
Recruitment status was Recruiting
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The investigators hypothesize that aberrant hypermethylation of tumour suppressor genes is an important mechanism for Epstein-Barr Virus (EBV) - related gastric carcinogenesis, the promoter hypermethylation status and the expression of S100A2 and TFF1 might be different between EBV-associated gastric cancer (GC) and non EBV-associated GC.
Condition |
---|
Gastric Cancer |
Study Type: | Observational |
Study Design: | Observational Model: Case Control Time Perspective: Cross-Sectional |
Official Title: | Expression of S100A2 and Trefoil Factor Family Members in Epstein-Barr Virus Related Gastric Cancer |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Sampling Method: | Probability Sample |
200 gastric tumour and normal tissue samples, as well as up to 50 non-neoplastic gastric tissues samples from individuals without gastric cancer (treated for other reasons, such as gastric ulcers) will be obtained from the tissue archives of the NUH Department of Pathology. These samples were selected because relevant clinical information of these samples are available from gastric database and will allow us to perform association studies.
Inclusion Criteria:
- Nil
Exclusion Criteria:
- Nil
Contact: Wei Peng Yong, MRCP, MB ChB | 65 6772 4670 | wei_peng_yong@nuhs.edu.sg |
Singapore | |
National University Hospital | Recruiting |
Singapore, Singapore, 119074 | |
Contact: Wei Peng Yong, MRCP,MB ChB 65 6772 4670 wei_peng_yong@nuhs.edu.sg |
No publications provided
Responsible Party: | Wei Peng Yong, National University Hospital, Singapore |
ClinicalTrials.gov Identifier: | NCT01100814 History of Changes |
Other Study ID Numbers: | GA01/08/08 |
Study First Received: | September 15, 2009 |
Last Updated: | April 7, 2010 |
Health Authority: | Singapore: Domain Specific Review Boards |
Additional relevant MeSH terms:
Stomach Neoplasms Gastrointestinal Neoplasms Digestive System Neoplasms Neoplasms by Site |
Neoplasms Digestive System Diseases Gastrointestinal Diseases Stomach Diseases |
ClinicalTrials.gov processed this record on October 17, 2012