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Angiographie and OCT in Macula and Retinal Diseases

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Stefan Sacu, Medical University of Vienna
ClinicalTrials.gov Identifier:
NCT01603823
First received: May 19, 2012
Last updated: May 21, 2012
Last verified: May 2012
History of Changes
  Purpose

The purpose of this study is to investigate the morphological and angiological retinal changes in different macular diseases.


Condition
Macular Edema

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Medical University of Vienna:

Enrollment: 30
Study Start Date: August 2008
Study Completion Date: September 2011
Primary Completion Date: February 2010 (Final data collection date for primary outcome measure)
Groups/Cohorts
Healthy volunteers
St.p. Pars plana vitrectomy

Detailed Description:

Recently, a new generation of OCT devices relying on spectral domain technology (SD-OCT) has been introduced and allows for higher-resolution imaging. Based on this technology we can identify variable changes at the retinal surface such as, retinal thickening with cyst formation, swelling in the inner and outer nuclear layers and subretinal fluid. The introduction of an eye-tracking mode has allowed a better insight into the development of retinal morphologic changes The aim of this study was to investigate the incidence and structural morphology of PCME after successful uncomplicated cataract surgery in patients with previous pars plana vitrectomy (PPV) and indocyanine green-assisted peeling of an epiretinal membrane and the internal limiting membrane (ILM).

  Eligibility

Ages Eligible for Study:   18 Years to 90 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Twenty eyes of 20 patients with previous 23-gauge PPV and ILM peeling (PPV group) and 15 consecutive eyes with senile cataract with a healthy macula (control group) were included.

Criteria

Inclusion Criteria:

  • previous 23-gauge PPV and ILM peeling

Exclusion Criteria:

  • history of branch retinal vein occlusion
  • central retinal vein occlusion
  • wet macular degeneration
  • diabetic retinopathy
  • uveitis or other inflammatory eye disease.
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01603823

Locations
Austria
Medical University of Vienna
Vienna, Austria, 1090
Sponsors and Collaborators
Medical University of Vienna
  More Information

No publications provided

Responsible Party: Stefan Sacu, Assoc.Prof., Medical University of Vienna
ClinicalTrials.gov Identifier: NCT01603823     History of Changes
Other Study ID Numbers: 10082007
Study First Received: May 19, 2012
Last Updated: May 21, 2012
Health Authority: Austria : Federal Ministry for Labour, Health, and Social Affairs

Keywords provided by Medical University of Vienna:
vitrectomy
cataract
macular edema

Additional relevant MeSH terms:
Edema
Macular Edema
Retinal Diseases
Signs and Symptoms
 Macular Degeneration
Retinal Degeneration
Eye Diseases

ClinicalTrials.gov processed this record on October 17, 2012