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The Effect Of Light On Scar Appearance

This study has been terminated.
(Study personnel left institution before study completion.)
Sponsor:
Information provided by:
Northwestern University
ClinicalTrials.gov Identifier:
NCT00544635
First received: October 12, 2007
Last updated: July 12, 2011
Last verified: July 2011
History of Changes
  Purpose

The goal of this project is to examine the ability of light exposure to improve the appearance of cutaneous scars.


Condition Intervention
Cutaneous Scars
 Device: no intervention
Device: light

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: The Effect Of Light On Scar Appearance

Resource links provided by NLM:

MedlinePlus related topics: Scars
U.S. FDA Resources

Further study details as provided by Northwestern University:

Primary Outcome Measures:
  • Scar vascularity [ Time Frame: 24 weeks ] [ Designated as safety issue: No ]
  • Scar pigmentation [ Time Frame: 24 weeks ] [ Designated as safety issue: No ]
  • Scar thickness [ Time Frame: 24 weeks ] [ Designated as safety issue: No ]
  • Scar length [ Time Frame: 24 weeks ] [ Designated as safety issue: No ]
  • Scar width [ Time Frame: 24 weeks ] [ Designated as safety issue: No ]
  • Scar surface area [ Time Frame: 24 weeks ] [ Designated as safety issue: No ]

Estimated Enrollment: 50
Study Start Date: November 2005
Study Completion Date: August 2006
Primary Completion Date: August 2006 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: A
scars will be treated with light
 Device: light
scars will be treated with light
Placebo Comparator: B
no intervention
 Device: no intervention
no intervention

Detailed Description:

Light would be efficacious in improving scar appearance due to its known effects on wound healing, acne, and its use for skin rejuvenation. Light interacts with cells and stimulates the production of new collagen and elastin. This same energy can be used to inhibit collagen formation and help improve scars.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Have two lesions that have been selected for excision
  • Have two cutaneous scars from previous excisions as part of a standard of care
  • Subjects are in good health
  • Subject has a willingness and the ability to understand and provide informed consent for the use of their tissue and communicate with the investigator

Exclusion Criteria:

  • Pregnancy or lactation
  • Subjects who are unable to understand the protocol or to give informed consent
  • Subjects with mental illness
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00544635

Locations
United States, Illinois
Northwestern Memorial Hospital
Chicago, Illinois, United States, 60611
Sponsors and Collaborators
Northwestern University
Investigators
Principal Investigator: Murad Alam, MD Northwestern University
  More Information

No publications provided

Responsible Party: Murad Alam, MD, Northwestern University
ClinicalTrials.gov Identifier: NCT00544635     History of Changes
Other Study ID Numbers: 1253-010
Study First Received: October 12, 2007
Last Updated: July 12, 2011
Health Authority: United States: Institutional Review Board

Additional relevant MeSH terms:
Cicatrix
Fibrosis
Pathologic Processes

ClinicalTrials.gov processed this record on October 17, 2012