Sleep Disorders Research Advisory Board

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NATIONAL CENTER ON SLEEP DISORDERS RESEARCH NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Sleep Disorders Research Advisory Board Meeting Minutes April 14, 2009 TABLE OF CONTENTS Attendees Introduction Adoption Of Minutes From The December 4, 2007 SDRAB Meeting NCSDR Director's Report: Michael Twery, PhD 2008 Sleep Disorders Research Plan Sleepiness and Health-Related Quality of Life Comments and Discussion Action Items Next Meeting Certification Sleep Disorders Research Advisory Board Page BOARD MEMBERS PRESENT Dr. Phyllis Zee, Chair Dr. Sonia Ancoli-Israel Ms. Rose Austin Dr. Charles Czeisler Dr. F. Javier Nieto Mr. Robert Waterman BOARD MEMBERS ABSENT Ms. Karen Cushing Dr. Estelle Gauda Dr. Howard Roffwarg EX OFFICIO MEMBERS PRESENT Dr. Michael Twery, NHLBI, Executive Secretary LIAISON MEMBERS PRESENT Dr. Merrill M. Mitler, NINDS FEDERAL EMPLOYEES PRESENT Mr. Peyvand Ghofrani, NHLBI, NIH Dr. Aaron Laposky, NHLBI, NIH Dr. Daniel Lewin, NHLBI, NIH MEMBERS OF THE PUBLIC PRESENT Mr. Darrel Drobnich, National Sleep Foundation Dr. Robert Stickgold, Harvard University Return to Table of Contents INTRODUCTION Dr Zee called the meeting to order. Dr. Twery welcomed those present. Conflict of interest issues, ethics disclosure, and responsibilities associated with NIH Advisory Board membership were identified for members to review. Meeting was announced in the Federal Register on March 23, 2009. Those in attendance introduced themselves. Return to Table of Contents ADOPTION OF MINUTES FROM THE JUNE 19, 2007 SDRAB MEETING Dr. Czeisler made a motion that the December 2007 meeting minutes be adopted without amendment, and Dr. Ancoli-Israel seconded the motion. The motion carried unanimously. Return to Table of Contents NCSDR DIRECTOR'S REPORT: Michael Twery, PhD Grant types and trends funded across NIH institutes having to do with sleep and circadian biology through fiscal year 2008 were presented. Support for sleep research through the National Center for Research Resource CTSA program was presented. Researchers were encouraged to take advantage of the CTSA infrastructure in developing research proposals. Existing and current opportunities for competitive applications were presented, including a summary of activities specific to National Center for Sleep Disorders Research. An update on American Recovery and Reinvestment Act of 2009 related activities was presented. Researchers were encouraged to stay informed and connected, and to continue to send in applications to the NIH. Return to Table of Contents SLEEP DISORDERS RESEARCH PLAN A process for revision of the strategic plan was presented. The process will be initiated by a public Request for Information (RFI) inviting comments on potential research directions. A Board working group would draft a preliminary draft for discussion with staff representing sleep research programs NIH-wide. The Board will adopt a draft document that will be disseminated for public comment. The Board will integrate these comments and provide a final Research Plan for consideration by NIH Institutes The goal is to develop an implementable strategy that broadly identifies potential roles of the NIH, and stakeholder communities. Following discussion, the Board concurred with the proposed process. Return to Table of Contents SLEEPINESS AND HEALTH-RELATED QUALITY OF LIFE The board discussed the Sleepiness and Health-related Quality of Life conference April 13th and 14th that highlighted sleep research activities NIH-wide A brief summary of the conference was presented by Dr. Zee. Return to Table of Contents COMMENTS AND DISCUSSION The board took comments and questions from the public and discussed them. The following areas of interest emerged: Connecting pediatric and adult sleep research. Disparities of self-reports vs. objective measures. Longitudinal studies are needed to assess chronic exposures. Contributions of sleep to other disorders. Examples include depression, ADHD and PTSD. Studies of sleep as a primary disease risk factor are needed. Intervention studies are needed to determine whether the treatment of sleep disorders improves clinically significant outcomes. For example: sleep apnea may contribute to depression; how can CPAP be used to reduce the risk of as a part of therapeutic strategy for depression? Giving sleep medications the night after trauma may reduce PTSD. Sleep research is not as widespread as it should be. Sleep medicine is not being taught in universities. Physicians do not routinely ask their patients about sleep quality and problems. Return to Table of Contents ACTION ITEMS Revision of the sleep disorders strategic research plan. Annual visits by National Center on Sleep Disorders Research staff with liaisons in other Federal offices and agencies. Return to Table of Contents NEXT MEETING The SDRAB meeting will continue to meet annually. The exact date has yet to be determined. Details will be posted when available on the SDRAB website http://www.nhlbi.nih.gov/meetings/sdrab/index.htm These Minutes will be presented to the full Board at its next regularly scheduled meeting for consideration, amendment as approved, and formal adoption. CERTIFICATION I hereby certify that the foregoing minutes are accurate and complete. Phyllis Zee, MD, PhD Chair, Sleep Disorders Research Advisory Board Michael Twery, PhD Executive Secretary, Sleep Disorders Research Advisory Board Return to Table of Contents

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