How To Use the Conserved Domain Database (CDD)

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Conserved Domains and Protein Classification

How to use CDD: examples

This page provides quick start guides for some common types of searches.
The CDD Help document provides detailed descriptions of the database content, search system, and display formats.
Once records of interest are retrieved, follow Entrez's "Links" to discover associations among previously disparate data.

Identify the putative function of a protein sequence.

Identify the specific amino acids in a protein sequence that are putatively involved in functions such as binding or catalysis, as mapped from conserved domain annotations to the query sequence.

View a protein query sequence embedded within the multiple sequence alignment of a domain model.

Interactively view the 3D structure of a conserved domain.

Find other proteins with similar domain architecture.

Interactively view the phylogenetic sequence tree for a conserved domain model of interest, with or without a query sequence embedded.

| Revised 31 January 2012 |