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What is the best award mechanism for my clinical research proposal?
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What is the best award mechanism for my clinical research proposal?NIH Award
These applications are commonly submitted by investigators
who have an idea for a research project. Most NHLBI
clinical research is investigator-initiated. Depending
on the type (observational or interventional), the cost of
the study and whether it will be a multi-center study, there
may be additional NHLBI NHLBI’s Guidelines for Investigator Initiated Epidemiology Studies include similar information regarding preparation and submission of applications to conduct epidemiology studies.
If you anticipate that your project
will cost more than $500,000 in direct costs Before making an award for an investigator-initiated clinical trial or epidemiology study, NHLBI will consider the desirability of substantial continued staff involvement in programmatic activities of the award. If such involvement is deemed appropriate by the Institute, the award mechanism will be converted to a Cooperative Agreement. The Terms and Conditions of Grant Award will reflect that arrangement.
This mechanism is designed to test the effectiveness of interventions that are based on strategies designed to promote healthful behaviors and to prevent or ameliorate disease in defined populations. D&E research is an extension or adaptation of interventions generally accepted as beneficial, to new populations or settings. Examples of such proposals, application preparation and submission details are given in Guidelines for Demonstration and Educational Research Grants.
These awards are used to support projects in early stages
of development such as the feasibility of a novel intervention
or therapy which may eventually lead to a breakthrough in
a particular research area. The details for application
and submission are discussed on the OER
This mechanism is used to support research projects that enhance the conduct of biomedical research through the development of infrastructure or resources. Please see the Guidelines for detailed information on deadlines and advanced permissions.
This program is used for planning grants that provide funding for pilot studies to obtain data critical to the successful design of a full-scale clinical trial. Please see the Guidelines for detailed information.
These mechanisms are used to support small businesses that wish to conduct research on drugs, devices, informatics and other scientific areas. NHLBI provides information on the SBIR/STTR program and current opportunities for small businesses in specific areas. These grants and contracts are currently using electronic submission. Information about receipt dates and Submitting Competing SBIR/STTR Grant Applications can be found on the OER website. The Application Instruction Guide can assist you in your submission. The purpose of the P01 mechanism is to encourage multidisciplinary approaches to the investigation of complex problems relevant to NHLBI's mission and to facilitate economy of effort, space, and equipment. PPGs are available to a group of several investigators with differing areas of expertise who wish to collaborate in research by pooling their talents and resources. They are designed to achieve results not attainable by investigators working independently. Guidelines for Program Project Grants will provide detailed information on how to prepare an application, submission and review procedures and Institute contacts. Allowable Requested Direct Costs for Program Projects gives additional budgetary information.
Career development awards support career development of investigators who conduct human subjects research. In addition to salary support, this mechanism provides funds for development and conduct of research that involves direct interaction with study subjects. Mentored Patient-Oriented Research Career Development Award describes these awards in greater detail.
This program features a new opportunity for promising postdoctoral scientists to receive both mentored and independent research support from the same award. OER offers additional information on the Pathway to Independence Award and who is eligible to apply.
Besides encouraging investigators to submit research applications
by the R01
Cooperative Agreements are grant
awards that incorporate substantial NHLBI involvement
in the project’s scientific
and administrative activities. If you are responding
to an RFA Many Clinical Research Networks are funded by a Cooperative Agreement. Network structure and procedures are described in detail in the RFA. If you want to know more about how a Network functions, you can go to the NHLBI Clinical Research Network Program for more information.
SCCORs are programs that foster communication and research in a multi-disciplinary environment in a specific scientific area outlined in the RFA. If you are responding to an RFA for a SCCOR, the RFA will guide you through the requirements and process, and will refer you to relevant NHLBI policies, such as the Program Description for Specialized Centers of Clinically Oriented Research, Special Instructions for SCCOR Grant Applications, and for some solicitations, Frequently Asked Questions. Page Last Updated: February 2011 |
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