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Fact Sheet
(Health Services Research Projects in Progress)

HSRProj, a database providing access to ongoing grants and contracts in health services research, is available free from the National Library of Medicine (NLM). It has its own interface at . It is also available via the NLM Gateway ( HSRProj is part of Other Information Resources. The NLM Gateway is a Web-based system that allows users of NLM services to initiate searches in multiple retrieval systems from one interface, providing "one-stop searching" for many of NLM's information resources.

To help HSRProj users navigate the new interface and the NLM Gateway, AcademyHealth has made available HSRProj Quick Search and Detailed Instructions . This Web site has tips on searching, downloading, and printing HSRProj records.

HSRProj contains descriptions of research in progress funded by federal and private grants and contracts for use by policy makers, managers, clinicians and other decision makers. It provides access to information about health services research in progress before results are available in a published form.

Records cover both grants and contracts awarded by major public and private funding agencies and foundations. Users can retrieve names of performing and sponsoring agencies, names and addresses of the principal investigator, beginning and ending years of the project, information about study design and methodology including demographic characteristics of the study group, number of subjects in the study population, population base of the study sample, and source of the project data. Records are indexed with NLM's Medical Subject Headings (MeSH®) and, when available, NIH's CRISP (Computer Retrieval of Information on Scientific Projects) keywords. Also, project descriptions are included whenever possible.

HSRProj is a joint effort of the AcademyHealth and the Cecil G. Sheps Center at the University of North Carolina with funding from the NLM. The National Information Center on Health Services Research and Health Care Technology (NICHSR) ( coordinates its continued development for NLM.

For more information on accessing HSRProj using the NLM products contact:

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For information on HSRProj content contact:

National Information Center on
Health Services Research and
Health Care Technology (NICHSR)
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Sample HSRProj Record

Title: Racial disparities in outcomes after acute myocardial infarction (AMI)
Investigator: Spertus, John A
Place: Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110
Email Address:
Performing Organization:Washington University School of Medicine
Supporting Agency: National Heart, Lung, and Blood Institute (NHLBI)
Initial Year: 2009
Final Year: 2013
Grant Support: P50HL077113-050002
Award Type: Contract
Abstract: Black Americans are believed to bear a disproportionate share of death and disability from cardiovascular disease. A principal goal of the Healthy People 2010 agenda is to eliminate such disparities. To date, however, studies of racial differences in acute myocardial infarction (AMI) outcomes have been limited to an examination of mortality without systematic evaluation of health status outcomes (symptoms, function and quality of life). In addition, the contribution of modifying factors such as co-morbidities (e.g. diabetes), differences in metabolism, or potential genetic determinants to racial difference in AMI outcomes have not been explored. Our preliminary data suggest that the health status outcomes (the symptoms, function and quality of life) of black patients are significantly worse than whites 6 months after AMI. Building upon this insight, we plan to enroll 4,500 patients over 3 years from 15 centers to test the fundamental hypothesis that black AMI patients have worse health status outcomes 1 year after an AMI than white patients. We also plan to evaluate the interaction of diabetes with racial background on outcomes in this cohort. Each consenting patient will undergo a baseline interview, abstraction of their medical record, donation of a fasting blood specimen for lipid and genetic analyses and detailed follow-up interviews at 6- and 12-months after their AMI. The specific aims of this SCCOR project include: 1) to describe racial differences in 1-year health status outcomes; 2) to describe racial differences in AMI care and test whether these differences account for observed disparities in 1-year health status outcomes; 3) to describe racial differences in the serum triglyceride lipidome among diabetic and non-diabetic AMI patients and test whether these differences account for disparities in 1-year outcomes; and 4) to determine whether racial differences in genetic variants of the PPAR regulatory complex among diabetic and non-diabetic AMI patients account for observed racial differences in 1-year outcomes. Through the rigorous description of racial differences in outcome, and the examination of multiple potential socio-economic, treatment, metabolic and genetic mediators, we will identify opportunities to eliminate racial disparities in outcomes after AMI.
Country: United States
State: Missouri (MO)
Zip Code: 63110
UI: HSRP20092241
Project Status: Ongoing

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