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Viewpoint | December 21, 2012  FREE
Weapons of Mass Destruction
Jerome P. Kassirer, MD
While our national leaders agonize about the threats in the Middle East from missiles, bombs, and automatic weapons that might fall into ...
Arch Intern Med. Published online December 21, 2012. doi:10.1001/jamainternmed.2013.4026
Research Letters | December 19, 2012  FREE
The First 2 Years of the European Medicines Agency's Policy on Access to Documents: Secret No Longer
Peter Doshi, PhD; Tom Jefferson, MD
Includes: Supplemental Content
On November 30, 2010, the regulatory agency for medications in Europe, the European Medicines Agency (EMA), announced a policy on access to ...
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Arch Intern Med. Published online December 19, 2012. doi:10.1001/jamainternmed.2013.3838
Commentary | December 19, 2012  FREE
The European Medicines Agency and the Brave New World of Access to Clinical Trial Data
Robert Steinbrook, MD
As of January 2014, the European Medicines Agency (EMA) will publish clinical trial data for the medications it considers for approval.1 After ...
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Arch Intern Med. Published online December 19, 2012. doi:10.1001/jamainternmed.2013.3842
Original Investigation | December 17, 2012 
A Randomized Comparison of Print and Web Communication on Colorectal Cancer Screening
David S. Weinberg, MD, MSc; Eileen Keenan, MA, CCRP; Karen Ruth, MS; Karthik Devarajan, PhD; Michelle Rodoletz, PhD; Eric J. Bieber, MD
BackgroundBackground New methods to enhance colorectal cancer (CRC) screening rates are needed. The web offers novel possibilities to educate patients and to ...
Arch Intern Med. Published online December 17, 2012. doi:10.1001/2013.jamainternmed.1017
Research Letters | December 17, 2012 
Optimal Interval for Routine Cytologic Screening in the United States
Jane J. Kim, PhD; Monisha Sharma, MS; Jesse Ortendahl, MS
Includes: Supplemental Content
Despite the success of cytology-based (Papanicolaou) screening in the United States, over 12 000 women develop and 4000 women die from cervical ...
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Arch Intern Med. Published online December 17, 2012. doi:10.1001/2013.jamainternmed.1034
Research Letters | December 17, 2012 
Healthcare and Lifestyle Practices of Healthcare Workers: Do Healthcare Workers Practice What They Preach?
Benjamin K. I. Helfand, MSc; Kenneth J. Mukamal, MD, MPH
Healthcare workers (HCWs) represent an important group in which to study individual health behaviors, both because they are more knowledgeable than others ...
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Arch Intern Med. Published online December 17, 2012. doi:10.1001/2013.jamainternmed.1039
Research Letters | December 17, 2012 
Effect of Patient Navigation on Enrollment in Cardiac Rehabilitation
Lisa Benz Scott, PhD; Shannon Gravely, PhD; Thomas R. Sexton, PhD; Sabrina Brzostek, PhD; David L. Brown, MD
Globally, cardiovascular diseases are the leading causes of morbidity and mortality.1 Secondary prevention measures, such as outpatient cardiac rehabilitation (OCR), effectively reduce ...
Arch Intern Med. Published online December 17, 2012. doi:10.1001/2013.jamainternmed.1042
Original Investigation | December 17, 2012 
Risk-Reducing Salpingo-oophorectomy and Ovarian Cancer Screening in 1077 Women After BRCA Testing
Gabriel N. Mannis, MD; Julia E. Fehniger, BA; Jennifer S. Creasman, MSPH; Vanessa L. Jacoby, MD, MAS; Mary S. Beattie, MD, MAS
BackgroundBackground For women at potentially increased risk for ovarian cancer, data regarding screening and risk reduction are limited. Previous studies have reported ...
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Arch Intern Med. Published online December 17, 2012. doi:10.1001/2013.jamainternmed.962
Invited Commentary | December 17, 2012 
Increasing Colorectal Cancer Screening Adherence: It's Going to Take More Than a Website:  Comment on “A Randomized Comparison of Print and Web Communication on Colorectal Cancer Screening”
Audrey H. Calderwood, MD; Hemant K. Roy, MD
Colorectal cancer (CRC) is the second leading cause of cancer deaths in the United States. Furthermore, it is preventable with routine screening ...
Arch Intern Med. Published online December 17, 2012. doi:10.1001/jamainternmed.2013.2527
Invited Commentary | December 17, 2012 
Role of Genetic Testing for Screening and Prevention for Ovarian Cancer:  Comment on “Risk-Reducing Salpingo-oophorectomy and Ovarian Cancer Screening in 1077 Women After BRCA Testing”
Victor Grann, MD, MPH; Maxine Ashby-Thompson, MPH
Genetic history of BRCA1/2 mutations identifies women who are at high risk for breast and ovarian cancer and who may benefit from ...
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Arch Intern Med. Published online December 17, 2012. doi:10.1001/jamainternmed.2013.2729
Perspectives | December 10, 2012  FREE
Words Before Actions
Sunita Puri, MD, MS
Mr C, a 78-year-old man with a history of Zollinger-Ellison syndrome with metastatic gastrinoma requiring subtotal gastrectomy with gastrojejunostomy, multiple past gastrointestinal ...
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Arch Intern Med. Published online December 10, 2012. doi:10.1001/2013.jamainternmed.826
Original Investigation | December 10, 2012 
Racial Differences in the Impact of Elevated Systolic Blood Pressure on Stroke Risk
George Howard, DrPH; Daniel T. Lackland, DrPH; Dawn O. Kleindorfer, MD; Brett M. Kissela, MD; Claudia S. Moy, PhD; Suzanne E. Judd, PhD; Monika M. Safford, MD; Mary Cushman, MD, MSc; Stephen P. Glasser, MD; Virginia J. Howard, PhD
BackgroundBackground Between the ages 45 and 65 years, incident stroke is 2 to 3 times more common in blacks than in whites, ...
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Arch Intern Med. Published online December 10, 2012. doi:10.1001/2013.jamainternmed.857
Invited Commentary | December 10, 2012 
Is Hypertension the Key to Reaching the Healthy People 2000 Goals by 2020? :  Comment on “Racial Differences in the Impact of Elevated Systolic Blood Pressure on Stroke Risk”
Anthony S. Kim, MD, MAS; S. Claiborne Johnston, MD, PhD
The 10-year health promotion and disease prevention goals set forth by the US Department of Health and Human Services in Healthy People ...
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Arch Intern Med. Published online December 10, 2012. doi:10.1001/2013.jamainternmed.863
Original Investigation | December 10, 2012 
Health System Factors and Antihypertensive Adherence in a Racially and Ethnically Diverse Cohort of New Users
Alyce S. Adams, PhD; Connie Uratsu, RN; Wendy Dyer, MS; David Magid, MD, MPH; Patrick O’Connor, MD, MA, MPH; Arne Beck, PhD; Melissa Butler, PharmD, MPH, PhD; P. Michael Ho, MD, PhD; Julie A. Schmittdiel, PhD
BackgroundBackground The purpose of this study was to identify potential health system solutions to suboptimal use of antihypertensive therapy in a diverse ...
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Arch Intern Med. Published online December 10, 2012. doi:10.1001/2013.jamainternmed.955
Original Investigation | December 10, 2012  FREE
Translating the Diabetes Prevention Program Lifestyle Intervention for Weight Loss Into Primary Care:  A Randomized Trial
Jun Ma, MD, PhD; Veronica Yank, MD; Lan Xiao, PhD; Philip W. Lavori, PhD; Sandra R. Wilson, PhD; Lisa G. Rosas, PhD; Randall S. Stafford, MD, PhD
Includes: Supplemental Content
BackgroundBackground The Diabetes Prevention Program (DPP) lifestyle intervention reduced the incidence of type 2 diabetes mellitus (DM) among high-risk adults by 58%, ...
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Arch Intern Med. Published online December 10, 2012. doi:10.1001/2013.jamainternmed.987
Original Investigation | December 10, 2012  FREE
Integrating Technology Into Standard Weight Loss Treatment:  A Randomized Controlled Trial
Bonnie Spring, PhD; Jennifer M. Duncan, PsyD; E. Amy Janke, PhD; Andrea T. Kozak, PhD; H. Gene McFadden, BA; Andrew DeMott, BA; Alex Pictor, BA; Leonard H. Epstein, PhD; Juned Siddique, PhD; Christine A. Pellegrini, PhD; Joanna Buscemi, PhD; Donald Hedeker, PhD
BackgroundBackground A challenge in intensive obesity treatment is making care scalable. Little is known about whether the outcome of physician-directed weight loss ...
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Arch Intern Med. Published online December 10, 2012. doi:10.1001/jamainternmed.2013.1221
Invited Commentary | December 10, 2012  FREE
The Future of Obesity Treatment: Accessible, Inexpensive, and Technology Based?:  Comment on “Integrating Technology Into Standard Weight Loss Treatment: A Randomized Controlled Trial”
Goutham Rao, MD; Katherine Kirley, MD
A staggering 68% of US adults are either overweight or obese.1 Current direct medical costs associated with treating obesity-related illness are roughly ...
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Arch Intern Med. Published online December 10, 2012. doi:10.1001/jamainternmed.2013.1232
Research Letters | December 3, 2012 
Availability of DMAA Supplements Despite US Food and Drug Administration Action
PhilipJ. Gregory, PharmD
The stimulant DMAA, also known as 1,3-dimethylamylamine, has been the subject of much controversy.1 In the United States, it is currently marketed ...
Arch Intern Med. Published online December 03, 2012. doi:10.1001/2013.jamainternmed.724
Original Investigation | December 3, 2012 
Urinary Tract Infection in Male Veterans:  Treatment Patterns and Outcomes
Dimitri M. Drekonja, MD, MS; Thomas S. Rector, PhD; Andrea Cutting, MA; James R. Johnson, MD
Includes: Supplemental Content
BackgroundBackground Lengthier antimicrobial therapy is associated with increased costs, antimicrobial resistance, and adverse drug events. Therefore, establishing minimum effective antimicrobial treatment durations ...
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Arch Intern Med. Published online December 03, 2012. doi:10.1001/2013.jamainternmed.829
Research Letters | December 3, 2012 
Preoperative Urine Cultures at a Veterans Affairs Medical Center
Dimitri M. Drekonja, MD, MS; Breanna Zarmbinski, BA; James R. Johnson, MD
The value of preoperative urine screening is unproven, except before urologic procedures, in which detection and treatment of asymptomatic bacteriuria is beneficial.1 ...
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Arch Intern Med. Published online December 03, 2012. doi:10.1001/2013.jamainternmed.834

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