Section 2: ART Cycles Using Fresh, Nondonor Eggs or Embryos (Part C)

Figure 27 is a bar graph representing percentages of ART cycles using fresh nondonor eggs or embryos that resulted in live births, by age of woman and history of previous ART cycles, among women with one or more previous births, 2008.

• Age <35, No previous ART and 1 or more previous births 43.8%, 1 or more previous ART cycles and 1 or more previous births 43.8%
• Age 35–37, No previous ART and 1 or more previous births 32.0%, 1 or more previous ART cycles and 1 or more previous births 33.5%
• Age 38–40, No previous ART and 1 or more previous births 23.0%, 1 or more previous ART cycles and 1 or more previous births 25.0%
• Age 41–42, No previous ART and 1 or more previous births 12.2%, 1 or more previous ART cycles and 1 or more previous births 14.6%
• Age 43–44, No previous ART and 1 or more previous births 5.5%, 1 or more previous ART cycles and 1 or more previous births 7.9%
• Age >44, No previous ART and 1 or more previous births 1.5%, 1 or more previous ART cycles and 1 or more previous births 2.5%

Figure 28 is a pie chart representing types of ART procedures using fresh nondonor eggs or embryos, 2008. Note: Cycles that were canceled before egg retrieval were classified as IVF, GIFT, or ZIFT based on the intended ART method. Total does not equal 100% due to rounding.

• IVF without ICSI, 35.6%

• IVF with ICSI, 64.3%
• GIFT, <0.1%
• ZIFT, <0.1%
• Combination of IVF with or without ICSI and either GIFT or ZIFT, <0.1%

Figure 29 is a bar graph representing percentages of egg retrievals that resulted in live births, by type of ART procedure, 2008.

• IVF without ICSI, 34.2%
• IVF with ICSI, 33.6%
• GIFT 21.2%
• ZIFT 17.8%
• Combination of IVF with or without ICSI and either GIFT or ZIFT, 40.0%

Figure 30 is a pie chart representing use of ICSI (intracytoplasmic sperm injection) in fresh nondonor cycles among couples with and without diagnoses of male factor infertility, 2008. Note: This is based on 67,258 cycles that used IVF with ICSI.  

• ICSI use among couples diagnosed with male factor infertility, 47.1%
• ICSI use among couples without a diagnosis of male factor infertility, 52.9%

Figure 31 is a bar graph representing percentages of retrievals that resulted in live births among couples diagnosed with male factor infertility who used IVF with ICSI (intracytoplasmic sperm injection), compared with couples not diagnosed with male factor infertility who used IVF without ICSI, by age of woman, 2008. Note: Cycles using donor sperm and cycles using GIFT or ZIFT are excluded. 

• Age <35, IVF with ICSI among couples with male factor infertility 45.6%, IVF without ICSI among couples with no male factor infertility 46.2%
• Age 35–37, IVF with ICSI among couples with male factor infertility 35.3%, IVF without ICSI among couples with no male factor infertility 36.4%
• Age 38–40, IVF with ICSI among couples with male factor infertility 26.8%, IVF without ICSI among couples with no male factor infertility 27.6%
• Age 41–42, IVF with ICSI among couples with male factor infertility 16.0%, IVF without ICSI among couples with no male factor infertility 15.5%
• Age 43–44, IVF with ICSI among couples with male factor infertility 7.2%, IVF without ICSI among couples with no male factor infertility 7.6%
• Age >44, IVF with ICSI among couples with male factor infertility 2.1%, IVF without ICSI among couples with no male factor infertility 3.9%

Figure 32 is a bar graph representing percentages of retrievals that resulted in live births among couples not diagnosed with male factor infertility, by use of ICSI (intracytoplasmic sperm injection) and age of woman, 2008. Note: Cycles using donor sperm and cycles using GIFT or ZIFT are excluded.

• Age <35, IVF with ICSI among couples with no male factor infertility 42.0%, IVF without ICSI among couples with no male factor infertility 46.2%
• Age 35–37, IVF with ICSI among couples with no male factor infertility 34.0%, IVF without ICSI among couples with no male factor infertility 36.4%
• Age 38–40, IVF with ICSI among couples with no male factor infertility 24.3%, IVF without ICSI among couples with no male factor infertility 27.6%
• Age 41–42, IVF with ICSI among couples with no male factor infertility 13.2 %, IVF without ICSI among couples with no male factor infertility 15.5%
• Age 43–44, IVF with ICSI among couples with no male factor infertility 5.3%, IVF without ICSI among couples with no male factor infertility 7.6%
• Age >44, IVF with ICSI among couples with no male factor infertility 0.9%, IVF without ICSI among couples with no male factor infertility 3.9%

Figure 33 is a pie chart representing numbers of embryos transferred during ART cycles using fresh nondonor eggs or embryos, 2008. Note: Total does not equal 100% due to rounding.

• One, 11.9%
• Two, 49.8%
• Three, 24.8%
• Four, 9.0%
• Five, 2.9%
• Six, 1.0%
• Seven or more, 0.5%
• Unknown, <0.1%

Figure 34 is a bar graph representing percentages of embryos transferred resulting in implantation among women using fresh nondonor eggs or embryos, by age group, 2008.

• Age <35, 34.0%
• Age 35–37, 24.8%
• Age 38–40, 16.8%
• Age 41–42, 9.3%
• Age 43–44, 4.5%
• Age >44, 2.0%

Figure 35 is a bar graph representing percentages of transfers that resulted in live births and percentages of multiple-infant live births for ART cycles using fresh nondonor eggs or embryos, by number of embryos transferred, 2008. Percentages of live births that were singletons, twins, and triplets or more are in parentheses. Note: In rare cases a single embryo may divide and thus produce twins. For this reason, a small percentage of twins resulted from a single embryo transfer, and a small percentage of triplets resulted when two embryos were transferred. 

• 1 embryo transferred: Percentage of transfers that resulted in live births 22.0%. Of these live births—98.0% were singletons, 1.9% were twins, and <0.1% were triplets or more. Note: Total does not equal 100% due to rounding.
• 2 embryos transferred: Percentage of transfers that resulted in live births 3.7%. Of these live births—65.5% were singletons, 33.6% were twins, and 0.9% were triplets or more. 
• 3 embryos transferred: Percentage of transfers that resulted in live births 34.7%. Of these live births—66.8% were singletons, 29.0% were twins, and 4.1% were triplets or more. Note: Total does not equal 100% due to rounding.
• 4 embryos transferred: Percentage of transfers that resulted in live births 28.8%. Of these live births—66.6% were singletons, 29.5% were twins, and 3.9% were triplets or more.
• 5 or more embryos transferred: Percentage of transfers that resulted in live births 24.0%. Of these live births—70.2% were singletons, 27.0% were twins, and 2.8% were triplets or more. 

Figure 36 is a bar graph representing percentages of transfers that resulted in live births and percentages of multiple-infant live births for ART cycles among women who were younger than 35, used fresh nondonor eggs or embryos, and set aside extra embryos for future use, by number of embryos transferred, 2008. Percentages of live births that were singletons, twins, and triplets or more are in parentheses. Note: In rare cases, a single embryo may divide and thus produce twins. For this reason, a small percentage of twins resulted from a single embryo transfer, and a small percentage of triplets resulted when two embryos were transferred.

• 1 embryo transferred: Percentage of transfers that resulted in live births 49.4%. Of these live births—98.0% were singletons, 1.9% were twins, and 0.1% were triplets or more.
• 2 embryos transferred: Percentage of transfers that resulted in live births 56.5%. Of these live births—58.0% were singletons, 41.0% were twins, and 1.1% were triplets or more.  Note: Total does not equal 100% due to rounding.
• 3 embryos transferred: Percentage of transfers that resulted in live births 49.6%. Of these live births—53.4% were singletons, 39.0% were twins, and 7.6% were triplets or more.
• 4 embryos transferred: Percentage of transfers that resulted in live births 47.7%. Of these live births—53.3% were singletons, 38.5% were twins, and 8.2% were triplets or more. 
• 5 or more embryos transferred: Percentage of transfers that resulted in live births 47.2%. Of these live births—52.0% were singletons and 48.0% were twins.

Figure 37 is a pie chart representing the day of embryo transfer among ART cycles using fresh nondonor eggs or embryos, 2008. Note: Day of embryo transfer is defined as the number of days following egg retrieval. Cycles using GIFT or ZIFT are excluded. Missing or implausible values for day of embryo transfer (i.e., 0 or >6) are not included. Total does not equal 100% due to rounding.

• Day 1, 0.1%
• Day 2, 4.6%
• Day 3, 55.6%
• Day 4, 2.6%
• Day 5, 34.9%
• Day 6, 2.1%

Figure 38 is a bar graph representing percentages of day 3 and day 5 embryo transfers using fresh nondonor eggs or embryos that resulted in live births, by age of woman, 2008. Note: Cycles using GIFT or ZIFT are excluded. This comparison is limited to transfers on day 3 and day 5. Embryo transfers performed on days 1, 2, 4, and 6 are not included because each of these accounted for a small proportion of procedures.   

• Age <35, Day 3, 42.6%, Day 5, 53.5%
• Age 35–37, Day 3, 33.9%, Day 5, 45.0%
• Age 38–40, Day 3, 26.1%, Day 5, 35.6%
• Age 41–42, Day 3, 15.1%, Day 5, 23.1%
• Age 43–44, Day 3, 6.9%, Day 5, 12.3%
• Age >44, Day 3, 2.3%, Day 5, 4.9%

Figure 39 consists of two pie charts representing the number of embryos transferred during ART cycles using fresh nondonor eggs or embryos for day 3 and day 5 embryo transfers, 2008. Note: Cycles using GIFT or ZIFT are excluded. This comparison is limited to transfers on day 3 and day 5. Embryo transfers performed on days 1, 2, 4, and 6 are not included because each of these accounted for a small proportion of procedures.

• Day 3:
  • 1 embryo transferred, 9.7%
  • 2 embryos transferred, 40.0%
  • 3 embryos transferred, 31.1%
  • 4 or more embryos transferred, 19.2%

• Day 5:
  • 1 embryo transferred, 13.0%
  • 2 embryos transferred, 67.0%
  • 3 embryos transferred, 15.5%
  • 4 or more embryos transferred, 4.6%
  • Note: Total does not equal 100% due to rounding.

Figure 40 depicts two pie charts, A and B, representing risks of having multiple-infant live births for ART cycles using fresh nondonor eggs or embryos for day 3 and day 5 embryo transfers, 2008. Note: Cycles using GIFT or ZIFT are excluded. This comparison is limited to transfers on day 3 and day 5. Embryo transfers performed on days 1, 2, 4, and 6 are not included because each of these accounted for a small proportion of procedures.

• Pie chart A represents 15,124 live births for day 3 embryo transfers.
  • Singletons: 71.5%
  • Total multiple-infant live births 28.4%, which is subdivided as follows:
    • Twins: 26.4%
    • Triplets or more: 2.0%
  • Note: Total does not equal 100% due to rounding.

• Pie chart B represents 13,892 live births for day 5 embryo transfers.
  • Singletons: 64.3%
  • Total multiple-infant live births 35.7%, which is subdivided as follows:
    • Twins: 34.0%
    • Triplets or more: 1.7%

Figure 41 is a bar graph representing percentages of transfers that resulted in live births and percentages of multiple-infant live births for day 5 embryo transfers among women who were younger than 35, used fresh nondonor eggs or embryos, and set aside extra embryos for future use, by number of embryos transferred, 2008. Percentages of live births that were singletons, twins, and triplets or more are in parentheses. Note: In rare cases, a single embryo may divide and thus produce twins. For this reason, a small percentage of twins resulted from a single embryo transfer, and a small percentage of triplets resulted when two embryos were transferred.    

• 1 embryo transferred: Percentage of transfers that resulted in live births 52.6%. Of these live births—98.2% were singletons, 1.7% were twins, and 0.1% were triplets or more. 
• 2 embryos transferred: Percentage of transfers that resulted in live births 59.6%. Of these live births—53.8% were singletons, 45.0% were twins, and 1.2% were triplets or more.
• 3 or more embryos transferred: Percentage of transfers that resulted in live births 49.3%. Of these live births—52.7% were singletons, 38.0% were twins, and 9.3% were triplets or more.

Figure 42 is a bar graph representing a comparison of percentages of transfers using fresh nondonor embryos that resulted in live births between ART cycles that used gestational carriers and those that did not, by age of ART patient, 2008. Note: Age categories reflect the age of the ART patient, not the age of the gestational carrier.

• Age <35, Used a gestational carrier 49.8%, Did not use a gestational carrier 47.1%
• Age 35–37, Used a gestational carrier 43.4%, Did not use a gestational carrier 37.4%
• Age 38–40, Used a gestational carrier 36.5%, Did not use a gestational carrier 28.1%
• Age 41–42, Used a gestational carrier 17.0%, Did not use a gestational carrier 16.5%
• Age 43–44, Used a gestational carrier 8.6%, Did not use a gestational carrier 7.8%
• Age >44, Used a gestational carrier 25.0%, Did not use a gestational carrier 2.7%