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rituximab
A recombinant chimeric murine/human antibody directed against the CD20 antigen, a hydrophobic transmembrane protein located on normal pre-B and mature B lymphocytes. Following binding, rituximab triggers a host cytotoxic immune response against CD20-positive cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms: | C2B8 Monoclonal Antibody CT-P10 IDEC-C2B8 monoclonal antibody | ||
US brand name: | Rituxan | ||
Foreign brand name: | Mabthera | ||
Abbreviation: | MOAB IDEC-C2B8 | ||
Code names: | IDEC-102 IDEC-C2B8 | ||