National Lung Screening Trial- from concept design to primary results


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Uploaded by on Oct 11, 2011

Richard Fagerstrom, Ph.D, Co-Chief Statistician National Lung Screening Trial (NLST) talks about the design of the cancer screening clinical trial that compared the effects of two ways of detecting lung cancer − low-dose helical CT and standard chest X-ray -- on lung cancer mortality rates. NLST researchers found 20 percent fewer lung cancer deaths among trial participants screened with CT. He explains why this complex trial required more than 50,000 participants in hundreds of locations and indicates that only a research organization such as the National Cancer Institute (NCI) could coordinate and manage such a important study.

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