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Investigating the causes of cancer through population-, family-, and lab-based research

Research & Publications

Hormuzd Katki's Research Featured by ASCO

In June, Hormuzd A. Katki, Ph.D., a tenure-track investigator in the Biostatistics Branch, spoke at the American Society of Clinical Oncology (ASCO) annual meeting in Chicago, Illinois, on his research demonstrating the benefits of incorporating human papillomavirus (HPV) testing into cervical cancer screening programs.

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News & Events

Nathaniel Rothman Honored by Vanderbilt-Ingram Cancer Center

In October, Nathaniel Rothman, M.D., M.P.H., M.H.S., a senior investigator in the Occupational and Environmental Epidemiology Branch, was honored as the Orrin Ingram Distinguished Lecturer at the Vanderbilt-Ingram Cancer Center in Nashville, Tennessee.

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DCEG Staff Updates

Shelia Hoar Zahm, DCEG Deputy Director, Retires

In December, Shelia Hoar Zahm, Sc.D., DCEG's Deputy Director, retired after 31 years of government service. Throughout her tenure at NCI, Dr. Zahm received numerous awards and accolades for her scientific accomplishments, breadth of scientific vision, and extraordinary organizational skills.

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Fellowship News

DCEG Fellows Awards for Research Excellence

The DCEG Fellows Awards for Research Excellence (D-FARE) program provides funding for travel to scientific meetings or conferences to fellows who have made exceptional contributions to research projects.

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Distinguished Visiting Scholars

DCEG Welcomes Silvia Franceschi

In September, DCEG welcomed as a Visiting Scholar Dr. Silvia Franceschi, head of the Section of Infections at the International Agency for Research on Cancer (IARC) in Lyon, France. She is recognized internationally for her research on the link between infectious agents and cancer.

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Unraveling Genetic Susceptibility to Melanoma

Tenure-track investigator Kevin Brown, Ph.D., Laboratory of Translational Genomics, has added a new chapter to DCEG's history of discovering the genetic factors that contribute to the risk of melanoma. As reported in a recent Nature article, Dr. Brown and colleagues used whole-genome sequencing to identify a novel, recurrent mutation, the E318K variant, in MITF. MITF is a gene that predisposes people to familial and sporadic melanoma (see Figure 1).

The MITF gene, or microphthalmia-associated transcription factor, helps control the development and function of pigment-producing cells called melanocytes. MITF has been considered an important gene in melanoma tumors for many years, being somatically amplified or mutated in some subsets of melanoma while strongly overexpressed in others.

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The DES Follow-up Study

In epidemiology, what can be learned from eight cases of an extremely rare tumor observed in the same clinic? Quite a lot, in fact, thanks to an inquisitive mother who asked whether her daughter's tumor was caused by "the medicine" the mother took during pregnancy and to the astute physicians who decided to follow up on her question. Read the full story >

Two Investigators Receive Scientific Tenure

NIH recently awarded scientific tenure to Amy Berrington de González, D.Phil., of the Radiation Epidemiology Branch, and Rachael Stolzenberg-Solomon, Ph.D., M.P.H., R.D., of the Nutritional Epidemiology Branch. Read the full story >