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Videos from NIH: 2012

  • July 24, 2012

    NEI Diabetes Toolkit (2:16)
    A community health worker talks about her experience using the National Eye Health Education Program's "Diabetes and Healthy Eyes Toolkit."

  • July 13, 2012

    The NIH Office of Behavioral and Social Sciences Research (4:31)
    A brief video about the NIH Office of Behavioral and Social Sciences Research and its mission.

  • June 8, 2012

    Rapid Tuberculosis Test (3:56)
    The driving force behind the rapid tuberculosis test that received World Health Organization endorsement is Dr. David Alland, Director of the Center for Emerging & Re-Emerging Pathogens at the New Jersey Medical School. The test uses DNA technology to diagnose tuberculosis in less than two hours...a huge reduction in time-to-results compared to conventional TB diagnosis. Dr. Alland received grant support from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

    The testing technology that it replaces, which is 125 years old, is far less reliable and requires three months to produce a diagnosis. The quicker and more accurate diagnoses produced by Dr. Alland's test will allow healthcare providers to begin tuberculosis treatment far sooner, sharply reducing the risk that infected individuals will spread the disease to others. It also will lead to more effective treatment of individual patients by telling clinicians whether disease-causing bacteria are drug-resistant.

    Dr. Alland began work on the screening test, which is called Xpert MTB/RIF (Mycobacterium tuberculosis/resistance to rifampin), more than a decade ago. The test took four years to develop, followed by the process of attracting funding to refine and manufacture it and then conducting the clinical trials that established its effectiveness. Financial support has come from the National Institutes of Health and the Bill and Melinda Gates Foundation. Dr. Alland's collaborators have been Cepheid, Inc., and FIND, the Foundation for Innovative New Diagnostics.

    WHO's endorsement of the test has been applauded by public health agencies including the U.S. President's Emergency Plan for AIDS Relief (PEPFAR), U.S. Agency for International Development and U.S. Department of Health and Human Services. The University of Medicine and Dentistry of New Jersey is proud to be the home of Dr. Alland's research, and congratulates him for his achievement.

  • June 7, 2012

    BSSR Lecture: Geospatial Methods in Health Research (1:20:43)
    Speaker - Ellen Cromley, PhD, University of Connecticut School of Medicine

    Geospatial methods have established their value in health research and in public health practice over the last 30 years, but there remains great potential for developing the role of these methods in health even further. This presentation outlines key geospatial concepts and their relevance to a broad range of issues in health research design, from study site selection and sampling to data acquisition and analysis to dissemination of findings to research protections for human subjects. The lecture includes an introduction to global and local spatial statistics, spatial regression models, and models of spatially varying processes. The presentation suggests ways to make health research more spatial and better able to uncover from the vast data available the key configurations of factors that come together in particular places to affect our health.

    Ellen Cromley is a medical geographer. She completed a B.A. in Urban and Environmental Studies at Case Western Reserve University, an M.A. in Geography from Ohio State University, and a Ph.D. in geography from the University of Kentucky. She co-authored GIS and Public Health (2002) with Sara McLafferty. The second edition was published in October, 2011. She began her career at Hunter Health Plan in Lexington, Kentucky, a Neighborhood Health Center, and worked for Appalachian Regional Hospitals before her career as a professor in the Department of Geography, University of Connecticut. She spent four years as Senior Research Associate at The Institute for Community Research in Hartford, Connecticut, as an investigator on grants funded by the National Institute of Alcohol Abuse and Alcoholism (alcohol as a factor in sexual risk behavior among young men in slum communities of Mumbai, India), the National Institute on Drug Abuse (housing status and stability among low income drug users in Hartford), and the National Institute of Mental Health (delivery of a multi-level intervention to promote female condom use). She has been a consultant on a research project funded by the National Cancer Institute environmental factors affecting physical activity in older women). Dr. Cromley has served as a career development award mentor for researchers at M.D. Anderson Cancer Center and the University of Connecticut Center for Health, Intervention, and Prevention who were seeking to integrate geographic methods and GIS into their work. She served as a member of the NIH Community-Level Health Promotion study section.

  • June 7, 2012

    BSSR Lecture Series: Infection, Inflammation, and Cardiovascular Disease among AmerIndians (1:16:25)
    Speaker - Hillard S. Kaplan, PhD

    The basic biology of the human cardiovascular and immune systems, and of glucose and lipid metabolism evolved under conditions of much greater energetic stress and pathogen burden than currently exist in the U.S and other developed countries. This talk focuses on two issues. The first is what can be learned about aging-related diseases by investigating cardiovascular health and disease, inflammation and immunosenescence, and energy metabolism in populations that currently live under conditions of basic subsistence, low energy balance and high pathogen load, without significant access to markets and public health.

    The second concerns possible solutions to the methodological challenges associated with conducting in-depth biological investigations in the context of population-level field research. To illustrate these issues, findings from on-going longitudinal research with Tsimane forager-farmers in Bolivia are presented. Initial results suggest that the role of inflammation in vascular and heart disease depends on energy balance and exercise. In addition, the roles of low- and high- density lipoproteins (LDL and HDL) in health and disease may also depend on energy balance and pathogen burden. With respect to immune function, chronic exposure to infectious disease throughout life appears to accelerate both immune system development and immunosenescence.

    Combining health care provision with research is an especially productive means of conducting both laboratory-based and population-level epidemiological investigations in developing world settings.

  • June 7, 2012

    BSSR Lecture Series: Virtual Patients, Cross-Cultural Research in Four Languages and Adaptive Trials (55:25)
    Speaker - Michael D. Fetters, MD, MPH, MA

    As promotion of high quality living and reduction of human suffering are noble goals of the health sciences, researchers need robust research tools to achieve these ends. Health sciences researchers by necessity investigate a wide variety of phenomena with relevance to basic sciences, biological, clinical, behavioral, epidemiological and philosophical sources. Health sciences researchers have a long tradition of applying rigorous qualitative and quantitative approaches to scientific inquiry. The health sciences thus provide a fertile ground for applying the newly emerging mixed methods paradigm and examining the results of the cross-pollination of qualitative and quantitative methods.

    Using examples of mixed methods research from projects about virtual patients, health care quality in a multicultural setting conducted in four languages, and improving development of adaptive clinical trials, I explore challenges and opportunities of mixing and integrating qualitative and quantitative methods in the field. Multidisciplinary collaborations are key for mixed methods researchers to apply and expand mixed methods inquiry while still meeting the litmus test of quality demanded in the health sciences.

  • June 7, 2012

    BSSR Lecture Series: Positive and Negative Reinforcement Underlying Adolescent Risk-Taking Behavior (1:05:51)
    Carl W. Lejuez, Ph.D., University of Maryland

    Adolescent risk taking presents a significant public health concern. The continued development of intervention approaches requires assessment strategies that can elucidate the processes underlying risk taking as it develops through adolescence. This presentation focuses on the use of behavioral measures to understand and model the development of adolescent risk taking behavior. Data are drawn from multiple sources including a 5 year longitudinal study funded by the National Institute on Drug Abuse (NIDA) focused on the role of positive reinforcement and a second study funded by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) extending this work to negative reinforcement processes. The presentation will conclude with a consideration of limitations of behavioral assessment approaches as well as future directions aimed at their combination with environmental, genetic, and neurobehavioral assessment.

  • June 7, 2012

    The Matilda White Riley Lecture: Social Isolation and Health (1:23:10)
    Speaker - Cacioppo, John T., National Institutes of Health (U.S.)

    Social species, by definition, form organizations that extend beyond the individual. These structures evolved hand in hand with behavioral, neural, hormonal, cellular, and genetic mechanisms to support them because the consequent social behaviors helped these organisms survive, reproduce, and care for offspring sufficiently long that they too reproduced, thereby ensuring their genetic legacy.

    Social isolation represents a lens through which to investigate these behavioral, neural, hormonal, cellular, and genetic mechanisms. Evidence from human and nonhuman animal studies indicates that isolation heightens sensitivity to social threats (predator evasion) and motivates the renewal of social connections. The effects of perceived isolation in humans share much in common with the effects of experimental manipulations of isolation in nonhuman social species: increased tonic sympathetic tonus and HPA activation, and decreased inflammatory control, immunity, sleep salubrity, and expression of genes regulating glucocorticoid responses. Together, these effects contribute to higher rates of morbidity and mortality in older adults.

  • June 7, 2012

    BSSR Lecture Series: PTSD Treatment and Prevention (1:11:22)
    Speaker - Barbara O. Rothbaum, Ph.D., ABPP, Emory University School of Medicine

    In the US, approximately 70% of adults will experience a traumatic event and 20% will develop posttraumatic stress disorder (PTSD). Both civilian and combat-related PTSD are major public health concerns with long term medical and mental health sequelae. Initial but transient PTSD symptoms may be considered part of the normal reaction to trauma, as they occur almost universally following severe enough traumas. In contrast, those who suffer from chronic PTSD show decreasing PTSD symptoms in the first month following trauma, which then remain fairly steady across time. They do not worsen; they just don't extinguish their original fear reactions. Therefore, PTSD can be viewed as a failure of recovery caused in part by a failure of fear extinction following trauma. Exposure therapy follows the same paradigms as extinction training and has received more evidence of its efficacy for treating PTSD than any other intervention. In this lecture, PTSD will be reviewed and treatments for PTSD will be discussed, with data on the efficacy of each, including exposure therapy (both imaginal exposure and virtual reality exposure therapy), EMDR, and pharmacotherapy. These are treatments for chronic PTSD. An important goal is secondary prevention, trying to intervene for those at risk in an attempt to prevent the development of PTSD. In the same way that there are rapid ED-based protocols for stroke or heart attack, we envision a personalized ED-based rapid intervention protocol that may prevent the development of PTSD following trauma. In translational research based on basic, preclinical, and clinical models for the consolidation of fear memories, pilot data with 137 emergency department (ED) patients seen an average of 11-12 hours after trauma exposure, randomly assigned to receive 3 sessions of exposure therapy beginning in the ED or assessment only, will be presented and discussed.

  • June 7, 2012

    BSSR lecture Series: Behavioral Economics, Classical Economics, Public Policy, Politics, and Health (1:12:25)
    Speaker - Loewenstein, George, National Institutes of Health (U.S.)

    Behavioral economics has enjoyed an expanding influence on policy, offering novel solutions to problems, including many involving health, that traditional economics, with its assumption of rational choice, often fails to even acknowledge. I will review the rationale for and tools of behavioral economics, in the process discussing several of my own field experiments evaluating novel behavioral interventions in the domain of health. However, I will also raise a variety of issues that need to be confronted for behavioral economics to have a continuing, constructive, influence on policy.

    We lack key evidence on the long-term consequences and potential unintended side-effects of behavioral interventions, and have not adequately thought through some of the ethical and practical considerations incumbent in many behaviorally informed policies. My broad conclusion will be that behavioral economics provides many useful tools and approaches, but can potentially play a negative role if it substitutes for, rather than complements, the types of policies favored by traditional economics.

  • June 5, 2012

    A Conversation with Dr. Marshall Nirenberg
    Dr. Marshall Nirenberg, with co-winners Robert W. Holley and Hr Gobind Khorana, was awarded the 1968 Nobel Prize for Physiology or Medicine in recognition "for their interpretation of the genetic code and its function in protein synthesis." Dr. Nirenberg was the first NIH researcher and federal employee to receive the honor. His work helped set the stage for the genomic era we are living in today. In the summer of 2009, Dr. Nirenberg reflected on his NIH career (which began in 1957).

  • May 31, 2012

    Carl Henn Memorial Bicycle Advocacy Award 2012 (15:59)
    The NIH Bicycle Commuter Club presented the first Carl Henn Memorial Bicycle Advocacy Award to Angela Atwood-Moore on Bike to Work Day, May 18 2012. Participating in the award ceremony at the Building One Pit Stop on the NIH campus in Bethesda Maryland, were Atwood-Moore, Diane Bolton, organizer of the NIH's Bike to Work Day, Nancy Breen a bicycle advocate and colleague of the late Carl Henn — and Henn's wife Carol, daughter Jessica, and his parents, Dwight and Diane Henn. Carl Henn was co-founder and president of the NIH Bicycle Commuter Club and a dedicated environmentalist, who died after being struck by lightning in a Rockville park in 2010. Atwood-Moore, who succeeded him as president of the Club, was honored for accomplishments, including the "NIH Bike Bucks" program, which allows NIH commuters to earn cash vouchers for miles ridden, which are redeemable at participating bike shops and the NIH Fitness Center. This year's award presentation video is followed by footage of the late Carl Henn at the NIH Executive Boulevard Pit Stop (which he established) on Bike to Work Day 2008 and 2010.

  • May 25, 2012

    NIH Harmonizes Over Hand Hygiene (04:05)
    The NIH Clinical Center hosted its first Hand Hygiene Awareness Day May 23, 2012, an event centered around educating staff, patients, and visitors about hand sanitation and safety. Well known for his musical talents, NIH Director Dr. Francis Collins organized the debut of a new group for the occasion, the Soap Sud Doo Whoppers. The group included Dr. David Henderson, Dr. Melinda Merchant, Lori Wiener, John Burklow, Carol Levinson, Nicole Plass, and Chauncey Buford.

  • May 24, 2012

    Bike To Work Day NIH 2011 (08:49)
    NIH riders checked-in at the NIH Building One Pit Stop for prizes and refreshments on Bike to Work Day, on the morning of May 20, 2011. National Cancer Institute Director (and former NIH Director) Dr. Harold Varmus offered tips on bicycling to NIH, which he called "the best urban commute in America." Participants also heard from NIH Director Dr. Francis Collins and his wife Diane Baker about their ride to the NIH campus that morning. For more information, visit the NIH Bicycle Commuter Club website: http://www.recgov.org/r&w/nihbike/index.html.

  • May 23, 2012

    Bike to Work Day @ NIH, May 18, 2012 (08:16)
    NIH Director Dr. Francis Collins and his wife Diane Baker participated in Bike to Work Day festivities at the National Institutes of Health in Bethesda, MD, on Friday, May 18, 2012. This video includes snapshots of activity at the Building 1 Pit Stop, a brief talk on the health benefits of bicycling by Dr. Collins, and a visit to the Executive Blvd. Pit Stop. For more information, visit the NIH Bicycle Commuter Club website: http://www.recgov.org/r&w/nihbike/index.html. Music: The NIH Jazz Band.

  • May 11, 2012

    BSSR Lecture Series: Regulation of the dopaminergic reward circuit and manic-like behavior (49:36) Speaker-McClung, Colleen A., National Institutes of Health (U.S.)
    Multiple studies have suggested that disruptions in circadian rhythms are central to the development of mood and addiction disorders. However, the mechanisms by which circadian genes regulate mood and reward-related circuitry remains unclear.

    Our laboratory has found that mice with a mutation in the Clock gene (Clock∆19) have a complete behavioral profile that bears a striking resemblance to human mania (including hyperactivity, lowered levels of anxiety, increased preference and self-administration of drugs, and lowered levels of depression-related behavior) which can be reversed with chronic lithium treatment. Furthermore, the ClockΔ19 mice have an increase in dopaminergic activity in the ventral tegmental area (VTA) which is also normalized with lithium treatment. We have taken multiple approaches including RNA interference and optogenetics to better understand how CLOCK regulates dopaminergic activity and how this regulation is involved in the control of behavior.

    Moreover, in collaboration with Kafui Dzirasa and Miguel Nicolelis at Duke University, we found that the ClockΔ19 mice not only have increased dopaminergic activity, but also have a defect in the ability of neurons in the cortico-limbic circuit to synchronize firing while animals are exploring specific tasks. Thus the CLOCK protein is not only involved in controlling rhythms over the course of 24 hrs, but is also involved in the synchronization of activity between brain regions over short periods of time.

    CLOCK functions as a transcription factor and we have identified direct target genes that control dopaminergic activity which appear to be important in the reversal of phenotypes by lithium. Taken together, these results begin to show the mechanisms by which circadian genes regulate mood and reward, and suggest novel therapeutic targets for the treatment of mania and addictive disorders.

  • May 11, 2012

    BSSR Lecture Series: Social Context as Risk Regulator: Extending the Stream of Causation (1:01:32)
    Speaker - Thomas A. Glass, Ph.D.

    Causation is the central problem of health research. Our causal discourse shapes what we study, and how and where we intervene. The potential outcomes model is the most widely accepted causal framework in Epidemiology. However, many "upstream" factors of greatest interest to social scientists are incompatible with this framework. This contributes to a narrow focus on individual-level "down-stream" risk factors and to ineffective interventions that target individuals while ignoring social context.

    This lecture will review causal discourse in light of the stream of causation metaphor, and suggest the concept of a risk regulator to address several key challenges. We attempt to upgrade this metaphor with a three-dimensional socio-environmental topography of risk. We argue that public health research may be improved by focusing on health behaviors as strategic action in the context of opportunities and constraints imposed by particular social settings. Several examples are given to illustrate how existing analytic tools can be used to study risk regulators. Finally, attention is given to the need for more contextually embedded data and emerging methods of data analysis that may improve the study of the role of social context in health research.

  • May 11, 2012

    BSSR Lecture Series: Decline Effects/Other Reasons Why We Need an Open Repository (56:34)
    Speaker - Jonathan Schooler

    Why do many published scientific effects appear to diminish with time? This so called "decline effect" has been observed both in individual labs (including my own) and in meta-analyses of findings across research in biology and medicine. Although some scientists dismiss the decline effect as simple statistical self-correction of initially exaggerated outcomes the truth is that we cannot be sure until we have better access to unpublished scientific work. In this talk I will review a variety of explanations for the decline effect including regression to the mean, publication bias, and gradual deterioration in experimental methods with replication. I will also consider the possibility that it may sometimes reflect genuine changes in scientific phenomena. In order to resolve the source of the decline effect I suggest the introduction of an open access repository for all research findings, which would enable researchers to fully log their hypotheses and methodologies ahead of time, and their results afterwards, regardless of outcome. Such a repository would not only shine light on the decline effect, but would also address a number of other difficulties stemming from the current lack of transparency in the scientific process.

  • May 11, 2012

    BSSR Lecture: The California Right Care Initiative (1:09:37)
    Speaker - Robert M. Kaplan, PhD

    Efforts to improve the quality of chronic disease care have often failed to improve patient outcomes. Averaged across all practices, patients receive the recommended care only about half the time. In California the performance rates for many standard chronic care quality measures, such as control of high LDL cholesterol or blood pressure, rank substantially below those of other states.

    Although protocols for managing these risk factors are known to be effective, the major problem is in achieving application of the protocols by providers and adherence among patients. Not all plans are poor performers and there is substantial variability across California medical plans. The best performing California health plans are among the national quality performance leaders and we have been focusing on high performing plans with the goal of spreading their practices to plans performing less well. This presentation reviews efforts from the NHLBI funded California Comparative Effectiveness and Outcomes Improvement (CEOI) Center, an entity that is developing a sustainable statewide infrastructure for Comparative Effectiveness Research on primary and secondary prevention of cardiovascular disease (CVD) for the 15 million people enrolled in California managed care plans.

    Partners in the effort include the State of California, three campuses of the University of California, RAND, and most of the major health plans serving California (Kaiser, Blue Cross, United, Atena). Results from a community wide project in San Diego demonstrate the effects of medical practice design changes on outcome systolic blood pressure, LDL cholesterol, and glycosylated hemoglobin. Methodologies for monitoring high and low performing groups will also be presented.

  • May 11, 2012

    BSSR Lecture: Harnessing Systems Science Methodologies To Inform Public Policy (1:57:43)
    Speaker - BSSR Lecture Series

    This symposium will demonstrate how systems science approaches (aka modeling and simulation) can be used to address policy-relevant questions, using childhood obesity as an exemplar. While doing so, it will showcase two mathematical (i.e., System Dynamics) models that are under development as a part of CompMod, the Comparative Modeling for Childhood Obesity Policy Network, which is part of the Envision network of mathematical and statistical modeling teams under NCCOR (the National Collaborative on Childhood Obesity Research).

    The symposium is designed to be accessible to audience members without a background in modeling. Each of two modeling projects will feature two speakers. The first speaker will describe the background of the problem that led to the need for mathematical models. The second speaker will explain the model building rationale and process along with some initial model outputs and interpretation. There will also be some description of: comparing models, the experiences and lessons learned in working on mathematical models for the first time, forming an interdisciplinary team, and working in a network of comparative modeling teams.

  • May 10, 2012

    BSSR Lecture: Environments, Inflammation, Transgenerational Perpetuation of Disparities in Health (59:45)
    Speaker - Thomas McDade, PhD

    Inflammation is an important part of human immune defenses against infectious disease, but recent research has implicated dysregulated inflammation in the pathophysiology of a wide range of chronic degenerative diseases, as well as adverse birth outcomes. Current understandings of the links between inflammation and disease are based primarily on research in post- epidemiologic transition populations with high levels of overweight/obesity, and low levels of infectious exposures.

    This presentation applies a populations- based, developmental, ecological framework to the study of inflammation in humans, and suggests that environments in infancy are critical to defining how inflammation is regulated in adulthood. The impact of early environments in turn modifies responsiveness to inflammatory stressors later in life, pointing toward a potentially important mechanism in the intergenerational transmission of disparities in health.

  • May 10, 2012

    Regulating Arterial Blood Pressure
    Dr. Jason Carter, Chair, Department of Kinesiology and Integrative Physiology, Health and Physical Education at Michigan Technological University, is researching how our nervous system reflects the state of our bodies health, and how we can improve it with non-pharmaceutical methods.

  • May 9, 2012

    Blood discovery: JAM-A protein keeps blood clots in check (0:30)
    Blood discovery: University of Delaware researchers find that JAM-A protein keeps blood clots in check Read more: http://tinyurl.com/87g6pkk

    This split-screen video shows, at left, the JAM-A protein at work in reducing a blood clot; at right, a blood clot grows unchecked in the absence of the JAM-A protein. The images were taken with an intravital microscope which enables scientists to view and image living cells and systems in real time at very high resolution. Only a small number of these high-tech tools are available in the U.S. Besides cardiovascular research, the intravital microscope can be used for studies of cancer, obesity, neuroscience and other biomedical fields.

    Although a number of different proteins in blood have been shown to slow clot formation, JAM-A is a far more powerful clot inhibitor, Ulhas Naik, director of the Delaware Cardiovascular Research Center at the University of Delaware, and his research team have discovered. Naik notes JAM-A could potentially be a biomarker doctors could use to determine if a patient is at higher risk for a heart attack or stroke.

    The study, led by scientists at the University of Delaware, is reported in the journal Blood. The research was supported by grants from the National Institutes of Health through the National Heart, Lung, and Blood Institute and the former National Center for Research Resources.

  • April 30, 2012

    Twin Joins TrialNet Diabetes Prevention Trial (03:23)
    A 19-year-old college student takes regular side trips from her campus in Chicago to travel south to Vanderbilt University Medical Center in Nashville for participation in a National Institutes of Health funded anti-CD3 type 1 diabetes prevention trial. Find out why this identical twin decided to take such a big step to further research for the prevention of diabetes.

    For more information about Vanderbilt's TrialNet research, go to: http://www.mc.vanderbilt.edu/root/vumc.php?site=trialnet

  • April 23, 2012

    Autism By The Numbers: Prevalence and Diagnosis Criteria Discussed (06:34)
    New numbers from the CDC puts the prevalence of autism at a record high 1 in 88 children. Yale Child Study Center professor James McPartland explains why a wide autism spectrum may explain this surge and how new diagnosis criteria from the American Psychiatric Association, might change the way the disorder is defined.

  • April 16, 2012

    Angela's Story (12:19)
    This is the story of Angela Irizarry, who was born with a life-threatening congenital heart defect, and the groundbreaking surgical technique developed by Yale pediatric surgeon Dr. Christopher Breuer. Angela was the first patient in the United States to receive a natural tissue-engineered vascular graft, made from her body's own cells. The research and clinical trials of Dr. Breuer were funded by grants from the National Institutes of Health

  • March 13, 2012

    Birth Defects: The Role of Research (12:52)
    Alan E. Guttmacher, M.D.
    Director, Eunice Kennedy Shriver National Institute of
    Child Health and Human Development

    January 2012
    http://www.nichd.nih.gov/news/releases/032112-birth-defects.cfm.

  • March 12, 2012

    The Intersection of Science & Security - Panel #3 (1:31:32)
    The Intersection of Science and Security: a Case Study Approach

    (For description please see Panel #1 below)

  • March 12, 2012

    The Intersection of Science & Security - Panel #2 (47:25)
    The Intersection of Science and Security: a Case Study Approach

    (For description please see Panel #1 below)

  • March 12, 2012

    The Intersection of Science & Security - Panel #1 (1:01:10)
    The Intersection of Science and Security: a Case Study Approach
    Continuing the global dialogue with the scientific and science policy community with a focus on Asia and the Western Pacific

    On December 9, 2011 the National Science Advisory Board for Biosecurity (NSABB) sponsored a workshop, The Intersection of Science and Security: a Case Study Approach, Continuing the global dialogue with the scientific and science policy community: focus on Asia and the Western Pacific. The purpose of this workshop was to give attendees a greater understanding of dual use research, including an awareness of strategies for managing dual use research of concern and an appreciation of how these issues are being addressed around the globe. The workshop utilized published articles as case studies, involving Mousepox and a SARS-like virus, as examples of dual use research of concern that highlight issues which investigators, institutions, journal editors, governments, and the scientific and security policy communities need to consider. In addition to presentations of the case studies, there were discussions among all panelists and attendees on global science and security issues as well as those of special interest within Asia and the Western Pacific, including information on training and education resources currently available.

    For more information on the NSABB and events and materials related to dual use research, see: www.biosecurityboard.gov

  • March 6, 2012

    Fluid secretion, pancreatic duct (:05)
    Measurement of pancreatic fluid secretion. The movie is of a sealed intralobular pancreatic duct in primary culture that is stimulated to secrete fluid into the duct lumen, as evident from expansion of the luminal space and enlargement of the duct.

  • March 2, 2012

    Keeping Noise Down On The Farm (03:26)
    Join Noisy Planet on this 3-minute video to Mountain View Farm in Purcellville, Va., to learn about how to protect your hearing if you live or work on a farm. It's not all quiet pastures and peeping baby chicks. In fact, you'll wish you had hearing protection when you hear the pig squeal

  • February 22, 2012

    Mitochondrial DNA Defects Cause Deafness (04:17)
    A Yale study, funded by the National Institutes of Health, reveals the pathway by which mitochondrial DNA defects cause maternally-inherited deafness. The study ma also open the way to learning more about age-related deafness. Gerald Shadel, Ph.D, professor of genetics and pathology at Yale School of Medicine, discusses the findings. The study appears in the journal Cell.

  • February 14, 2012

    2012 Red Dress Fashion Show (06:42)
    In 2012, The Heart Truth marked a decade of commitment to women's heart health. During February's American Heart Month, the National Heart, Lung, and Blood Institute (NHLBI) reaffirmed its commitment to increasing awareness about heart disease among women and helping women take steps to reduce their own personal risk of developing heart disease. One of the campaign's signature American Heart Month activities, the Red Dress Collection Fashion Show, serves as a red alert to women that heart disease doesn't care what you wear—it's the #1 killer of women. With the generous support of celebrities and the fashion community, the Red Dress took center stage on the runway again this February as the national symbol of women and heart disease awareness.

  • February 10, 2012

    Glaucoma Webinar (46:29)
    The National Eye Institute recently held a webinar entitled, "Eye Health Knowledge and Information Preferences of People at Risk For Glaucoma: Results of Nationwide Focus Groups."

  • February 9, 2012

    Meryl Comer Discusses The Importance of Alzheimer's Research Funding (0:50)
    While attending a press conference where new efforts to fight Alzheimer's disease were announced, Meryl Comer, the president of the Geoffrey Beene Foundation Alzheimer's Initiative, discusses the importance of funding research.

  • February 9, 2012

    Meryl Comer Discusses Alzheimer's Disease (03:17)
    Meryl Comer, the president of the Geoffrey Beene Foundation Alzheimer's Initiative, discussed her personal experience with Alzheimer's disease at a press conference where new efforts to fight Alzheimer's disease were unveiled.

  • February 7, 2012

    National Wear Red Day 2012 - A flash mob thank you from the NIH (04:07)
    February 3, 2012 is National Wear Red Day. To celebrate those who help advance heart disease research and care every day, the National Institutes of Health held a special event.

    The celebration was made possible with support from the National Institutes of Health Clinical Center, the Foundation for the NIH, and the National Heart, Lung, and Blood Institute.

  • January 31, 2012

    The Economic Cost of Uterine Fibroids (04:44)
    Dr. James Segars, head of the National Institute of Child Health and Human Development's Unit on Reproductive Endocrinology and Infertility, explains results of the study, "The Economic Annual Cost of Uterine Leiomyomata in the United States."

  • January 25, 2012

    NIH Employee Assistance Program (01:20)
    The NIH Employee Assistance Program provides personalized consultation, short-term support, referral and follow up services to enhance personal and professional wellbeing.

  • January 5, 2012

    2011 NIH Early Independence Award Scientists (02:20)
    2011 NIH Early Independence Award Scientists

Videos from NIH: 2011

  • December 20, 2011

    NIH Overview (1:36)
    No description available

  • December 20, 2011

    Tenure/Tenure-Track Opportunities at NIH (1:02)
    No description available.

  • December 5, 2011

    Watching Life Develop From a Single Cell (2:30)
    Researchers at Yale University, in collaboration with the NIH and Sloan-Kettering recently developed a new, very powerful imaging technology that allows them to visualize with single cell resolution, the development of an organism in its entirety. This technology is 30 times faster than the fastest microscopes that are conventionally used in the field.

  • November 29, 2011

    02 Francis S. Collins (17:23)
    Calling the NIAMS' 25th anniversary "a chance to reflect on where we have come from," as well as an opportunity "to think about the future," Dr. Francis Collins praises the Institute's leadership for anticipating scientific opportunities, for strong corporate citizenship within the NIH, for tackling diseases that are "common and chronic and costly and crippling," and for supporting "a portfolio of research that has made a real difference in the health of the nation and the health of the world." Collins describes the NIAMS as consistently making strides in treatment development and understanding the immunology and genetics of its mission areas, from funding the Study of Osteoporotic Fractures in the mid-1980s to supporting research that recently led to the first FDA-indicated treatment for lupus in more than 50 years. Explaining one of the reasons he is excited about plans for the NIH's proposed National Center for Advancing Translational Sciences, Collins says, "We have the chance to focus even more intentionally now on taking the deluge of basic science discoveries pouring out of laboratories across all of the diseases that are in the NIAMS' portfolio and making sure that we apply those as quickly as possible in the translational arena."

  • November 21, 2011

    26 Stephen I_ Katz OUTRO (1:44)
    Dr. Stephen Katz thanks the organizations and presenters who made the NIAMS twenty-fifth anniversary symposium possible, and thanks the audience for attending. He encourages the audience to visit the NIAMS poster session in an adjacent room, saying the posters provide a good sample of "the outstanding quality of science that we have here." Concluding the symposium portion of the day's celebration, Katz says, "This year, and this day in particular, has highlighted the very real progress and promise of our efforts."

  • November 21, 2011

    25 Annie Kennedy (12:22)
    Annie Kennedy and Tiffany Schmidt discuss the role of the NIAMS Coalition, a group of more than 70 professional and voluntary organizations concerned with the research of the NIAMS. Describing herself as the "ghost of Coalitions past and present," Kennedy explains how the Coalition has worked to create opportunities for legislators and policymakers to interact with patients and scientists so they can better understand the value of the NIAMS and its role in lessening the burden on the nation of the diseases within its mission. Kennedy describes the NIAMS' commitment to its stakeholders as "unparalleled," and says, "I'm proud to report that the Coalition is more robust today than ever before." As the "ghost of Coalitions future," Schmidt says, "One of the things we will try to do is bring patients, researchers and physicians to Capitol Hill, so that we can go from office to office," educating representatives and senators about NIAMS' mission areas. Encouraging members in the audience to join the Coalition in sharing their own stories with legislators, she says, "I was thinking today how much members of Congress would have learned if they had been sitting here today."

  • November 21, 2011

    24 Panel Discussion4 (18:23)
    Panel 4 participants take questions from the audience.

  • November 21, 2011

    23 Maria Morasso (13:05)
    Dr. Maria Morasso describes her research on mouse models of ectodermal dysplasias—a group of skin disorders caused by genetic mutations—to illustrate more generally how basic research can lead to clinical applications. She emphasizes that the end goal in basic research is always the better understanding of a process or pathology with the intention of using that knowledge to improve quality of life. Morasso also emphasizes that science is not done alone, saying that researchers need mentors and they need to work in teams.

  • November 21, 2011

    22 Cato Laurencin (17:36)
    Dr. Cato Laurencin says that to meet the grand challenges in medicine, we need three things: "bold ideas; bold, smart people; and organizations that believe in us and in funding ideas that are bold." Describing tissue engineering as one of the bold ideas of the 1980s, he says his group is now trying to think in terms of "regenerative engineering," which he describes as "the integration of tissue engineering with advances in material science, stem cells sciences and developmental biology." Laurencin credits the NIAMS with providing ongoing financial support for such engineering, with widening the field, and for having the courage to believe in bold ideas.

  • November 21, 2011

    21 Helen Lu (17:27)
    Dr. Helen Lu describes the challenge facing the tissue engineer today with an analogy: "How do you connect a rope to a wall without any fixation pins or screws?" Surgeons today use mechanical fixation devices, she explains, but for tissue engineers like herself, Lu says the hope is that in the near future, they can better mimic how ligaments and tendons are naturally connected to the bone. She says her long-term goal, and the goal of others in her field, is to eventually be capable of engineering total joint systems. Lu also talks about the value of having researchers interact with clinicians and the role of mentorship in science, saying, "We stand on the shoulders of giants." She thanks her mentors, including Dr. Cato Laurencin, and her students, as well as her collaborators at the NIAMS intramural research program and at private institutions.

  • November 21, 2011

    20 Emily Smith (06:12)
    At the age of two, Emily Smith was diagnosed with juvenile arthritis, and she describes the decade that followed as a "roller coaster" in which her arthritis waxed and waned, and her parents and doctors experimented with different dosages of the standard drugs available. Shortly before her eleventh birthday, however, Smith started taking one of the then-new biologic treatments, and everything changed, dramatically. After an early childhood spent going "days, and sometimes months, nearly immobile from pain and inflammation," in high school she was pole vaulting on the track team. She says, "I have been lucky enough to see kids with RA [rheumatoid arthritis] completely avoid the misery that I went through. I am able to live my life to the fullest."

  • November 21, 2011

    19 Robert Carter 2 (03:03)
    Dr. Robert Carter, Deputy Director of NIAMS, introduces and moderates Scientific Session and Patient Perspective Panel 4.

  • November 21, 2011

    18 Panel Discussion 3 (19:51)
    Panel 3 participants take questions from the audience

  • November 21, 2011

    17 Amye Leong (14:57)
    Amy Leong shares her story of being diagnosed with rheumatoid arthritis at age 18—and later with Sjögren's syndrome and osteoporosis—and her journey to become a patient advocate, speaker and author who defies disability. About her role as the international spokesperson for the Bone and Joint Decade, Leong says, "One of things I have been a strong advocate for is the engagement of patients at the research level. And that sounds really bizarre: 'We're going to study you; we don't want to talk to you about your cells!' But I would propose to you that when you engage us in the development of research design, we will open your eyes in ways that you will find very beneficial."

  • November 21, 2011

    16 Jane Salmon (15:20)
    Dr. Jane Salmon thanks the NIAMS for taking a risk in funding her team's PROMISSE study of lupus patients, despite what she calls its "unconventional" hypothesis. She describes the early NIAMS-funded mouse studies that led to PROMISSE's development and shares some of PROMISSE's results to date, including findings that suggest that women with lupus who have antiphospholipid antibodies are at increased risk for preeclampsia, a disease of pregnancy that endangers the lives of both fetuses and mothers. Salmon also notes data that show, importantly, that women with lupus who do not have antiphospholipid antibodies are likely to have a healthy pregnancy if their lupus is stable at conception

  • November 21, 2011

    15 John Stanley (17:04)
    Dr. John Stanley, a professor in the department of dermatology at the University of Pennsylvania, argues that although historically there has been "a long lag between research and improvement in patient care," those lag times are getting shorter, thanks, in large part, to public investment in the research enterprise. Stanley uses pemphigus as his example, describing how it took 100 years to achieve an understanding of the histology of the disease, leading to the first major advance for patients. But he says more recent advances—from discovering prednisone as a pemphigus treatment to improvements in diagnosis—have benefitted patients more rapidly. Other examples of research with tangible benefits include discovering antibodies associated with pemphigus, coming to understand pemphigus as an autoimmune disease, and the development of animal models of pemphigus.

  • November 21, 2011

    14 Susana Serrate-Sztein (10:21)
    Dr. Susana Serrate-Sztein, Director of the Division of Skin and Rheumatic Diseases, NIAMS, introduces and moderates Scientific Session and Patient Perspective Panel 3.

  • November 21, 2011

    13 Panel Discussion 2 (20:06)
    Panel 2 participants take questions from the audience

  • November 21, 2011

    12 George Beach (09:43)
    George Beach shares how a new biologic treatment gave his artistic career a second act after 25 years of being unable to paint due to joint damage and pain caused by rheumatoid arthritis. When his arthritis treatment began to "kick in," in 2001, Mr. Beach says his "brushes came alive again." Later that same year, the World Trade Center tragedy and America's response to it inspired Mr. Beach to put his rediscovered skills to work in his award-winning painting, Indivisible, featured in this video.

  • November 21, 2011

    11 John O Shea (14:13)
    Dr. John O'Shea describes the NIH as a place where "people come from around the world and give their heart and soul to tough problems." He recounts his own tough problem, "a bedside to bench to bedside story," which began in 1994, when his team discovered a protein, Jak3, the absence of which causes severe immunodeficiency in humans. O'Shea's team cloned the gene that encodes Jak3, about which he says, "Back when we were doing this, it was actually really hard to clone a gene...now you can just sit at home, drinking a cup of coffee, and go on the Internet, and you can find out all this stuff. But it took us months, and months and months." The slow-going work paid off: O'Shea and his colleagues have collaborated with Pfizer to develop tofacitinab, a compound that helps block transplant rejections and might help treat certain autoimmune diseases.

  • November 21, 2011

    10 Daniel Kastner (16:05)
    Dr. Daniel Kastner recalls "the wonderful opportunities" that the NIH afforded a young scientist and shares some behind-the-scenes stories of his research discoveries. About finding the gene for Familial Mediterranean Fever, Kastner says, "This was back at that wonderful time, the dawn of the Human Genome Project, when with positional cloning—that method in which if you could recruit a group of families, if you knew it was a single gene disease—you could discover the gene, even if you didn't know anything about it. Seeing the dramatic inflammatory phenotype...I thought: That's for me!...The adventure was on."

  • November 21, 2011

    09 Robert Carter (05:25)
    Dr. Robert Carter, Deputy Director of NIAMS, introduces and moderates Scientific Session and Patient Perspective Panel 2.

  • November 21, 2011

    08 Panel Discussion (19:05)
    Panel 1 participants take questions from the audience.

  • November 21, 2011

    07 Priscilla Ciccariello (08:44)
    Priscilla Ciccariello, who lost her husband, eldest son and a grandson to complications of Marfan syndrome, a connective tissue disorder, describes how new surgeries and other treatment advances have given a more hopeful future to her surviving two sons and the many others living with Marfan syndrome.

  • November 21, 2011

    06 Clifford Rosen (12:43)
    NDr. Clifford Rosen, director of clinical and translational research and senior scientist at the Maine Medical Center Research Institute, gives a "tour" of the recent history of osteoporosis research and the NIH's and the NIAMS' role in sponsoring much of it. Among the examples Rosen highlights are genetic studies that have improved our understanding of a major cell-signaling pathway in osteoporosis, the wealth of new basic and translational research spawned by that understanding, and the importance of data that continue to come from the NIH-funded Study of Osteoporotic Fractures, now in its twenty-first year.

  • November 21, 2011

    05 Richard Moxley (16:04)
    Dr. Richard Moxley discusses how NIAMS and NIH funding has moved the field of muscular dystrophy research forward via a critical disease registry, a network of research centers, and individual study grants. He discusses the strides being made, particularly in the field of myotonic dystrophy—the most common of the muscular dystrophies—"because of the breakthroughs that we think we are now poised to pursue," including the discovery that toxic ribonucleic acid (RNA) causes the gene defect in myotonic dystrophy and the exciting advances that have been made in treating the disease in animal models.

  • November 21, 2011

    04 Joan McGowan (03:28)
    Dr. Joan McGowan, Director of the Division of Musculoskeletal Diseases, NIAMS, introduces and moderates Scientific Session and Patient Perspective Panel 1.

  • November 21, 2011

    03 John Porter (23:49)
    Taking the audience back to the time before "iPads, iPhones, and Twitter," the Honorable John Edward Porter reminds the audience of how the NIAMS has changed the research landscape, saying, "Twenty-five years ago, there was no Pediatric Rheumatology Clinic to diagnose and treat children with arthritis and other rheumatic diseases. Twenty-five years ago, the discovery of proteins that regulate bone growth and repair—findings which paved the way for advances in bone-grafting and cartilage regeneration—had yet to occur. Today, the millions of people living with arthritis, lupus, inherited skin disorders, and other diseases are grateful for these and other findings." Porter also discusses the current budget climate from the perspective of someone who served many years on the U.S. House of Representatives subcommittee that oversees the NIH budget, emphasizing the need for both political parties to work together to resolve the nation's budget crisis. He notes that it was a Democrat and a Republican working together, "Congressmen Henry Waxman of California and the late Ed Madigan of Illinois, who formally established the NIAMS 25 years ago." Porter encourages bench scientists and clinicians to create opportunities to share their stories of medical research and breakthroughs with the public and Congress.

  • November 21, 2011

    01 Dr Katz (10:53)
    Dr. Stephen Katz thanks the nearly 300 friends of the NIAMS who are present for joining in the day's festivities, emphasizing the role of the NIAMS' many partners that make its work possible, including patients, the public, and the professional and patient groups that make up the NIAMS Coalition. Noting that much of the work honored by the symposium is really the result of trans-NIH partnerships, he says, "These collaborations are really how the NIH works, and how the NIH works best." Katz directs the audience's attention to the NIAMS 25th Anniversary Milestone Banner, which highlights a representative snapshot of NIAMS-supported research over the years, as well as the Institute's interactions with researchers, clinicians, patients, and the public. Katz thanks the NIAMS staff, calling them "one of our Institute's most valuable resources," and discusses the accomplishments of his predecessors, the late Dr. Lawrence Shulman, a world-renowned rheumatologist who served as the first NIAMS Director, from 1986 to 1994, and Dr. Michael Lockshin, who led the NIAMS as its Acting Director following Dr. Shulman's retirement.

  • November 7, 2011

    Protein Actin (0:20)
    The protein actin coats individual granules during the final phase of regulated exocytosis in a salivary acinar cell. As exocytosis occurs, the coated granules collapse and disappear from view.

  • November 7, 2011

    Granules in a salivary acinar cell (0:07)
    Granules in a salivary acinar cell fuse singly to the plasma membrane during regulated exocytosis

  • November 4, 2011

    Síntomas de un ataque al corazón (02:07)
    Uploaded by NIHOD on Nov 4, 2011 El video de los Síntomas de un ataque al corazón describe los 7 síntomas principales de un ataque al corazón. Con el objetivo de crear un video emotivo que motive a las mujeres a hacerse ver por el médico cuando sienten estos síntomas, el video cuenta las historias personales de varias mujeres que sufrieron un ataque al corazón. Este video es presentado por el Instituto del Corazón, los Pulmones, y la Sangre de los Institutos Nacionales de la Salud.

  • November 4, 2011

    Factores de riesgo para la enfermedad del corazón (2:36)
    El video de Factores de riesgo para la enfermedad del corazón explica los dos tipos de factores de riesgos asociados con el ataque al corazón: los factores que una persona puede controlar y los que no puede controlar. Conocer los factores de riesgo es muy importante ya que teniendo un factor de riesgo duplica la posibilidad de que una persona desarrolle la enfermedad del corazón. Este video es presentado por el Instituto del Corazón, los Pulmones, y la Sangre de los Institutos Nacionales de la Salud.

  • November 2, 2011

    Telework at the NIH (1:23)
    No description available

  • November 2, 2011

    NIH Job: Program Analyst (0:57)
    No description available

  • November 2, 2011

    NIH Job: Nurse (0:57)
    No description available

  • November 2, 2011

    NIH Job: Management Analyst (0:54)
    No description available

  • November 2, 2011

    Living in Bethesda (1:22)
    No description available

  • November 2, 2011

    NIH Job: Budget Analyst (0:57)
    No description available

  • November 2, 2011

    NIH Job: Biologist (0:53)
    No description available

  • November 2, 2011

    NIH Job: Administrative Officer (0:59)
    No description available

  • November 1, 2011

    Common Vision Problems (2:34)
    A doctor explains common vision problems, including nearsightedness, farsightedness, astigmatism, and presbyopia.

  • October 21, 2011

    The NIH Mission - It's About Life (1:50)
    No description available

  • October 21, 2011

    The NIH Campus (1:29)
    No description available

  • October 21, 2011

    NIH Job: IT Specialist (0:53)
    No description available

  • October 18, 2011

    Clinical Research Nurses 2 (1:20)
    Clinical research nurses tell about their pleasure in working with clinical trial participantse

  • October 18, 2011

    Clinical Research Nurses (0:46)
    Clinical research nurses tell about their pleasure in working with clinical trial participants

  • October 5, 2011

    NIH Job: Grants Management Specialist (0:56)
    No description available

  • October 5, 2011

    NIH Job: Contract Specialist (0:50)
    No description available

  • October 5, 2011

    NIH Clinical Center celebrates Lasker-Bloomberg Award (1:11)
    The NIH Clinical Center is the 2011 recipient of the Lasker-Bloomberg Public Service Award given by the Albert and Mary Lasker Foundation. The award honors the Clinical Center for serving as a model institution that has transformed scientific advances into innovative therapies and provided high-quality care to patients since 1953. The award also recognizes the Clinical Center's rich history of medical discovery through clinical research.

  • September 29, 2011

    NIH Peer Review Revealed (14:52)
    NIH Peer Review Revealed provides a front-row seat to a NIH peer review meeting. Real scientists from the scientific community review fictional but realistic grant applications for scientific merit.

    The NIH Center for Scientific Review created this video for new applicants and others who want to know how the National Institutes of Health evaluates the 80,000+ grant applications it receives each year. With the majority of NIH's $31 billion budget supporting grants to researchers, these reviews are key to future advancements in science and health.

    View our video FAQs and learn more at http://www.csr.nih.gov/video/video.asp

    Check out our companion video: NIH Tips for Applicants on YouTube. Reviewers and staff at the National Institutes of Health offer their insights to researchers seeking to improve their chances of getting a grant from NIH.

  • September 16, 2011

    What Happens to Your NIH Grant Application Video (22:14)
    Our "What Happens to Your Grant Application" video gives new applicants for NIH grants access to one of our popular outreach presentations. It describes how the NIH Center for Scientific Review handles applications submitted to NIH. The video then describes how our panels of outside experts review applications so NIH can find and fund the ones with the most promise.

    Packed with many key details, this video complements our other YouTube videos: "NIH Peer Review Revealed" and "NIH Tips for Applicants." In these videos, NIH reviewers and staff offer their insights to researchers seeking to improve their chances of getting a grant from NIH.

    Learn more at http://www.csr.nih.gov/video/video.asp

  • September 1, 2011

    NIH Job: Health Scientist Administrator - Scientific Review Officer (0:56)
    No description available

  • August 29, 2011

    NIH Job: Health Scientist Administrator - Program Officer (0:59)
    No description available

  • August 26, 2011

    NIH Job: Medical Officer (0:51)
    No description available

  • August 19, 2011

    The Heart Truth (2:06)
    NHLBI's The Heart Truth campaign video tells the story of the campaign as well as the community events and local programs associated with this initiative. The centerpiece of The Heart Truth is the Red Dress. The Red Dress is a red alert for women to take care of their hearts at all ages.

  • August 19, 2011

    Heart Disease Risk Factors (2:03)
    Heart Attack Risk Factors address the two types of risk factors associated with heart attacks, factors that a person can control and factors they cannot. Knowing the risk factors is so important because having just one risk factor doubles a person's chance of developing heart disease.

  • August 15, 2011

    Heart Attack Warning Symptoms (2:38)
    Heart Attack Warning Symptoms speaks to the 7 main symptoms of a heart attack. It uses real women's stories to personalize the heart attack experience, and encourages women who experience these symptoms to get checked out.

  • August 11, 2011

    Dissemination & Implementation Conference: Day 2 11:15-12:00 (45:29)
    4th Annual NIH Conference on the
    Science of Dissemination and Implementation:
    Policy and Practice

    Agenda: Day 2: March 22, 2011
    Policy Dissemination Research: Are We Making Legislation or Sausage?
    Ross C. Brownson, PhD
    Professor of Epidemiology, Washington University in St. Louis

    About the conference:

    There is a recognized need to close the gap between research evidence and clinical and public health practice and policy. How is this best accomplished? Dissemination and implementation research in health seeks to answer this question, and is gaining momentum as a field of scientific inquiry. The goal of the annual NIH Conference on the Science of Dissemination and Implementation is to facilitate growth in the research base by providing a forum for communicating and networking about the science of dissemination and implementation.

  • August 11, 2011

    Dissemination &Implementation Conference: Day 2 8:30-9:30 (01:02:06)
    4th Annual NIH Conference on the
    Science of Dissemination and Implementation:
    Policy and Practice

    Agenda: Day 2: March 22, 2011
    Overview of Dissemination and Implementation Research Opportunities
    David Chambers, DPhil (NIH)
    Russell E. Glasgow, PhD (NIH)
    Francis Chesley, MD (AHRQ)
    David Atkins, MD, MPH (VA)

    About the conference:

    There is a recognized need to close the gap between research evidence and clinical and public health practice and policy. How is this best accomplished? Dissemination and implementation research in health seeks to answer this question, and is gaining momentum as a field of scientific inquiry. The goal of the annual NIH Conference on the Science of Dissemination and Implementation is to facilitate growth in the research base by providing a forum for communicating and networking about the science of dissemination and implementation.

  • August 11, 2011

    Dissemination & Implementation Conference: Day 1 11:15-12:45 (01:37:22)
    4th Annual NIH Conference on the
    Science of Dissemination and Implementation:
    Policy and Practice

    Agenda: Day 1: March 21, 2011

    Invited Panel: International Perspectives on Dissemination and Implementation Research Policy and Practice
    Russell E. Glasgow, PhD (Moderator) National Cancer Institute, NIH

    Knowledge Translation Canada
    Jeremy Grimshaw, MBChB, PhD, FRCGP
    Canadian Cochrane Network and Centre
    University of Ottawa

    Sharon Straus, MD, MSc, FRCPC, HBSc
    Li Ka Shing Knowledge Institute of St. Michael's Hospital
    University of Toronto

    WHO's Perspectives on Implementation Research for Policy and Practice
    Jane Kengeya-Kayondo, MD, MSc
    World Health Organization

    Closing the Treatment Gap: Research Approaches to Implementing What We Know Works in Routine Health
    Care in Developing Countries
    Vikram Patel, PhD
    London School of Hygiene & Tropical Medicine (UK)

    About the conference: There is a recognized need to close the gap between research evidence and clinical and public health practice and policy. How is this best accomplished? Dissemination and implementation research in health seeks to answer this question, and is gaining momentum as a field of scientific inquiry. The goal of the annual NIH Conference on the Science of Dissemination and Implementation is to facilitate growth in the research base by providing a forum for communicating and networking about the science of dissemination and implementation.

  • August 11, 2011

    Dissemination & Implementation Conference: Day 1 8:30-9:30 (57:08)
    4th Annual NIH Conference on the
    Science of Dissemination and Implementation:
    Policy and Practice

    Agenda: Day 1: March 21, 2011

    Welcome
    Helen I. Meissner, ScM, PhD
    Office of Behavioral and Social Sciences Research

    Opening Remarks
    Robert Kaplan, PhD
    Director, Office of Behavioral and Social Sciences Research

    The Implementation Imperative: Closing the Gaps Between Research, Practice and Policy
    Carolyn M. Clancy, MD
    Director, Agency for Healthcare Research and Quality

    About the conference:

    There is a recognized need to close the gap between research evidence and clinical and public health practice and policy. How is this best accomplished? Dissemination and implementation research in health seeks to answer this question, and is gaining momentum as a field of scientific inquiry. The goal of the annual NIH Conference on the Science of Dissemination and Implementation is to facilitate growth in the research base by providing a forum for communicating and networking about the science of dissemination and implementation.

  • August 11, 2011

    Dissemination & Implementation Conference: Workshop (02:12:16)
    4th Annual NIH Conference on the
    Science of Dissemination and Implementation:
    Policy and Practice
    March 21-22, 2011

    NIH Sponsored Training on
    Impact Evaluation Using Randomized Trials
    In Partnership with Abdul Latif Jameel Poverty Action Lab

    About the Workshop

    Rigorous impact evaluation is a critical ingredient in evidence-based policy. Within the health sector, randomized controlled trials (RCTs) are considered standard practice in clinical research. However, evaluation of programs and policies to implement large-scale health interventions tend to be far less rigorous. Much of this is due to the fact that researchers, health practitioners and policymakers are sometimes unsure of how to reconcile the rigor of clinical trials with the uncontrolled diversity of the field, particularly when operating in a developing country context. Political, logistical and ethical constraints can often make the ideal research design appear infeasible.

    The Abdul Latif Jameel Poverty Action Lab (J-PAL) is a network of empirical research economists who specialize in international development and have acquired substantial expertise running randomized evaluations in such settings. Researchers in the J-PAL network have adapted the driving characteristic of RCTs—randomization of the treatment—to test the effectiveness of health programs and policies in what are often difficult environments.

    J-PAL, in partnership with the NIH, is offering a workshop on how to incorporate rigorous impact evaluation methodologies into operations and implementation research (OR/IR). J-PAL researchers will share their experience evaluating programs on HIV/AIDS, immunization, maternal health, reproductive health, human resources for health and mobile health technologies. Using these case studies, they will cover the research design and implementation considerations necessary to conduct randomized evaluations. Through this workshop, participants will acquire many of the tools and lessons necessary to implement rigorous impact evaluations in a number of contexts and over a range of global health issues.

    Participants should be researchers, clinicians, or senior program managers with a Masters, PhD, or equivalent who are interested in implementation research. Some research background expected. Participants may come prepared with the details of a clinical or public health program/intervention that they are interested in studying, including the setting, context, and the size and characteristics of the target population.

    Sponsors
    U.S. Department of Health & Human Services (HHS)
    National Institutes of Health (NIH)
    John E. Fogarty International Center (FIC)
    National Cancer Institute (NCI)
    Office of Behavioral and Social Sciences Research (OBSSR)

  • July 6, 2011

    The NIH Clinical Center's Guide to Blood Droplet Freezing (6:02)
    The NIH Clinical Center's Guide to Blood Droplet Freezing

  • June 30, 2011

    NICHD's Scientific Vision: The Next Decade (4:31)
    This video features highlights from the scientific visioning process coordinated in 2011 by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), part of the National Institutes of Health. The aim of this process is to develop a scientific vision that inspires NICHD, its many partners, and the research community to think ambitiously and broadly, across traditional disciplinary boundaries, about new ways to advance knowledge and meet health needs in this era of unprecedented scientific innovation.

  • June 27, 2011

    "i on NIH" - June 2011 vodcast (14:12)
    Featured in this month's episode; the winning entry in a video contest about the MedlinePlus, a special high school graduation message from the director of the National Institutes of Health, the first in a series of segments about how the first of the baby boomers are turning 65 this year, and a segment about cataracts

  • June 22, 2011

    NIH K-12 Lessons About Bioscience Challenge (1:56)
    The trans-NIH Science Education Resource Group announces a new challenge.

  • June 10, 2011

    NIH K-12 Lessons About Bioscience Challenge (1:56)
    The trans-NIH Science Education Resource Group announces a new challenge

  • May 26, 2011

    Genetic Underpinnings of Alopecia Areata (4:18)
    In alopecia areata, immune system cells attack the rapidly growing cells in hair follicles. This can lead to hair loss on the scalp and elsewhere. The NIAMS supported the establishment of a National Alopecia Areata Registry, providing a central information source for researchers, and a liaison between patients and investigators.

  • May 25, 2011

    The NIAMS 25th Anniversary (3:28)
    In 2011, the NIAMS marked its 25th anniversary with the theme "Improving Lives Through Discovery." Since 1986, the NIAMS has made research advances toward helping people with diseases in the bones, joints, muscles, and skin. A Scientific Symposium on June 13, 2011, and other events throughout the year celebrate the anniversary.

  • May 23, 2011

    Strengthening the Culture of Responsibility with Respect to Dual Use Research and Biosecurity (46:51)
    Bilateral video-teleconference (VTC) entitled Strengthening the Culture of Responsibility with Respect to Dual Use Research and Biosecurity, sponsored by the National Institutes of Health and the Chinese Academy Science and in cooperation with the InterAcademy Panel: The Global Network of Science Academies, the International Union of Microbiology Society, the International Union of Biochemistry and Molecular Biology, and the National Academies of Science. This event was a satellite session of the "Trends in Science and Technology Relevant to the Biological and Toxin Weapons Convention" in Beijing, China.

    The aim of the VTC was to raise awareness of the dual use issue among workshop participants, to engage participants in a discussion on fostering a culture of responsibility, and to inform the National Science Advisory Board for Biosecurity (NSABB), a group of non-government experts that advises the USG on dual use research and other biosecurity issues, on the views of these international scientists and policy experts from over 30 countries. The VTC linked participants at the workshop site in Beijing with key NIH/NSABB experts in Bethesda, MD. Issues discussed included the principal features or attributes of a culture of responsibility and strategies for promoting, creating, and sustaining a culture of responsibility.

  • May 5, 2011

    Multilevel Interventions in Health Care Conference: Conference Closing Remarks (22:20)
    Multilevel Interventions in Health Care: Building the Foundation for Future Research Goals

    At the end of the conference, National Cancer Institute leaders, Drs. Taplin, Klein, and Ballard-Barbash, provide closing thoughts about the conference, future steps in multilevel research, and related projects and efforts in multilevel interventions.

    Conference Description
    The research conference sponsored by the National Cancer Institute assembled health care researchers, clinicians, and administrators to discuss the importance of multilevel approaches to improving health care quality in the United States. It occurred over two days and was associated with the American Society for Preventive Oncology's (ASPO) annual meeting in March of 2011.

    This presentation is one of 13 research papers. The conference offered platforms for participant discussion and engagement regarding the opportunities and challenges of multilevel intervention research. Recorded sessions, presentation slides, and additional resources are available at http://cancercontrol.cancer.gov/mli/index.htm

  • May 5, 2011

    Multilevel Interventions in Health Care Conference: Keynote address by Otis Brawley, MD (42:24)
    Multilevel Interventions in Health Care: Building the Foundation for Future Research Goals

    With his background as an oncologist, researcher and administrator, Dr. Otis Brawley (American Cancer Society) brings his unique perspective on multilevel interventions in clinical practice to Saturday's keynote address and consider how health care changes and multilevel interventions.

    Conference Description
    The research conference sponsored by the National Cancer Institute assembled health care researchers, clinicians, and administrators to discuss the importance of multilevel approaches to improving health care quality in the United States. It occurred over two days and was associated with the American Society for Preventive Oncology's (ASPO) annual meeting in March of 2011.

    This presentation is one of 13 research papers. The conference offered platforms for participant discussion and engagement regarding the opportunities and challenges of multilevel intervention research. Recorded sessions, presentation slides, and additional resources are available at http://cancercontrol.cancer.gov/mli/index.htm

  • May 5, 2011

    Multilevel Interventions in Health Care Conference: Q&A session moderated by Russell Glasgow, PhD (59:41)
    Multilevel Interventions in Health Care: Building the Foundation for Future Research Goals Dr. Glasgow (National Cancer Institute), the moderator for Introduction Papers, entertains questions and comments from conference participants and engages the panel of presenters in discussion of the issues covered in their papers. Conference Description The research conference sponsored by the National Cancer Institute assembled health care researchers, clinicians, and administrators to discuss the importance of multilevel approaches to improving health care quality in the United States. It occurred over two days and was associated with the American Society for Preventive Oncology's (ASPO) annual meeting in March of 2011. This presentation is one of 13 research papers. The conference offered platforms for participant discussion and engagement regarding the opportunities and challenges of multilevel intervention research. Recorded sessions, presentation slides, and additional resources are available at http://cancercontrol.cancer.gov/mli/index.htm.

  • May 5, 2011

    Multilevel Interventions in Health Care Conference: Presentation by Steven Clauser, PhD (26:41)
    Multilevel Interventions in Health Care: Building the Foundation for Future Research Goals Synthesis and Emerging Themes Lead author: Steven Clauser, PhD (National Cancer Institute) This presentation will synthesize emerging themes from the earlier papers and describe key challenges in moving the field of multilevel intervention research forward in cancer care delivery. Conference Description The research conference sponsored by the National Cancer Institute assembled health care researchers, clinicians, and administrators to discuss the importance of multilevel approaches to improving health care quality in the United States. It occurred over two days and was associated with the American Society for Preventive Oncology's (ASPO) annual meeting in March of 2011. This presentation is one of 13 research papers. The conference offered platforms for participant discussion and engagement regarding the opportunities and challenges of multilevel intervention research. Recorded sessions, presentation slides, and additional resources are available at http://cancercontrol.cancer.gov/mli/index.htm

  • May 5, 2011

    Multilevel Interventions in Health Care Conference: Discussant comments by Ernest Hawk, MD, MPH (14:37)
    Dr. Hawk (MD Anderson Cancer Center), the section discussant, comments on the issues presented from papers by Drs. Warnecke and Khoury on the second day of the conference.

    Conference Description
    The research conference sponsored by the National Cancer Institute assembled health care researchers, clinicians, and administrators to discuss the importance of multilevel approaches to improving health care quality in the United States. It occurred over two days and was associated with the American Society for Preventive Oncology's (ASPO) annual meeting in March of 2011.

    This presentation is one of 13 research papers. The conference offered platforms for participant discussion and engagement regarding the opportunities and challenges of multilevel intervention research. Recorded sessions, presentation slides, and additional resources are available at http://cancercontrol.cancer.gov/mli/index.htm

  • May 5, 2011

    Multilevel Interventions in Health Care Conference: Presentation by Muin Khoury, MD, PhD (15:04)
    Multilevel Interventions in Health Care: Building the Foundation for Future Research Goals

    Multilevel Research and the Challenges of Implementing Genomic Medicine Lead author: Muin Khoury, MD, PhD (Centers for Disease Control and Prevention)

    Advances in genomics and related fields, promise a new era of personalized medicine in the cancer care continuum. Nevertheless, there are fundamental challenges in integrating genomics into current cancer practice. This paper explores how multilevel research can contribute to evaluation, implementation and dissemination of genomic medicine. The paper synthesizes existing information in a framework of multilevel intervention methodology and makes recommendations for future research on the integration of genomic medicine into the cancer care continuum.

    Conference Description
    The research conference sponsored by the National Cancer Institute assembled health care researchers, clinicians, and administrators to discuss the importance of multilevel approaches to improving health care quality in the United States. It occurred over two days and was associated with the American Society for Preventive Oncology's (ASPO) annual meeting in March of 2011.

    This presentation is one of 13 research papers. The conference offered platforms for participant discussion and engagement regarding the opportunities and challenges of multilevel intervention research. Recorded sessions, presentation slides, and additional resources are available at http://cancercontrol.cancer.gov/mli/index.htm

  • May 5, 2011

    Multilevel Interventions in Health Care Conference: Presentation by Richard Warnecke, PhD (13:15)
    Multilevel Interventions in Health Care: Building the Foundation for Future Research Goals

    Linking Multilevel Approaches to Issues in Health Policy Lead author: Richard Warnecke, PhD (University of Illinois at Chicago)

    As health care reform is being considered and advanced, solutions being proposed for the delivery of health care begin with addressing access issues by reducing financial barriers. This paper uses breast cancer as a marker of health care delivery and analyzes how the view from communities facing health disparities provides insights for policy. The role of multilevel research in addressing gaps in our knowledge will also be addressed.

    Conference Description
    The research conference sponsored by the National Cancer Institute assembled health care researchers, clinicians, and administrators to discuss the importance of multilevel approaches to improving health care quality in the United States. It occurred over two days and was associated with the American Society for Preventive Oncology's (ASPO) annual meeting in March of 2011.

    This presentation is one of 13 research papers. The conference offered platforms for participant discussion and engagement regarding the opportunities and challenges of multilevel intervention research. Recorded sessions, presentation slides, and additional resources are available at http://cancercontrol.cancer.gov/mli/index.htm

  • May 5, 2011

    Multilevel Interventions in Health Care Conference: Discussant comments by Martin Charns, DBA (16:03)
    Multilevel Interventions in Health Care: Building the Foundation for Future Research Goals

    Dr. Charns (Boston University; United States Department of Veterans Affairs), the section discussant, comments on the issues presented from papers by Drs. Devers and Yano on the second day of the conference.

    Conference Description
    The research conference sponsored by the National Cancer Institute assembled health care researchers, clinicians, and administrators to discuss the importance of multilevel approaches to improving health care quality in the United States. It occurred over two days and was associated with the American Society for Preventive Oncology's (ASPO) annual meeting in March of 2011.

    This presentation is one of 13 research papers. The conference offered platforms for participant discussion and engagement regarding the opportunities and challenges of multilevel intervention research. Recorded sessions, presentation slides, and additional resources are available at http://cancercontrol.cancer.gov/mli/index.htm

  • May 5, 2011

    Multilevel Interventions in Health Care Conference: Presentation by Elizabeth Yano, PhD (13:16)
    Multilevel Interventions in Health Care: Building the Foundation for Future Research Goals

    Implementation and Spread of Multilevel Interventions in Practice: Implications for the Cancer Care Continuum Lead author: Elizabeth Yano, PhD (United States Department of Veterans Affairs; University of California, Los Angeles)

    This paper will discuss applications of researched multilevel interventions into real world practice, including issues of implementation and sustainability.

    Conference Description
    The research conference sponsored by the National Cancer Institute assembled health care researchers, clinicians, and administrators to discuss the importance of multilevel approaches to improving health care quality in the United States. It occurred over two days and was associated with the American Society for Preventive Oncology's (ASPO) annual meeting in March of 2011.

    This presentation is one of 13 research papers. The conference offered platforms for participant discussion and engagement regarding the opportunities and challenges of multilevel intervention research. Recorded sessions, presentation slides, and additional resources are available at http://cancercontrol.cancer.gov/mli/index.htm

  • May 5, 2011

    Multilevel Interventions in Health Care Conference: Presentation by Kelly Devers, PhD (18:01)
    Multilevel Interventions in Health Care: Building the Foundation for Future Research Goals

    Healthcare Reform and Multilevel Interventions and Research: Big Changes Go Hand in Hand with Big Science Lead author: Kelly Devers, PhD (Urban Institute)

    The purpose of this paper is to describe and discuss the implications of the Affordable Care Act, and other major pieces of legislation passed in 2009, for cancer care and related research. Continuing with these major areas and provisions, we illustrate and discuss how the implementation of these reforms occurs at multiple levels of the health system. General concepts must be translated into specific and often-complex, multilevel interventions that often vary based on states and local markets prior history, interpretation, and current capacities and constraints. Recommendations will be presented for how best to develop this multilevel infrastructure to ensure that the Big Changes underway are accompanied by a new, health services research Big Science approach.

    Conference Description
    The research conference sponsored by the National Cancer Institute assembled health care researchers, clinicians, and administrators to discuss the importance of multilevel approaches to improving health care quality in the United States. It occurred over two days and was associated with the American Society for Preventive Oncology's (ASPO) annual meeting in March of 2011.

    This presentation is one of 13 research papers. The conference offered platforms for participant discussion and engagement regarding the opportunities and challenges of multilevel intervention research. Recorded sessions, presentation slides, and additional resources are available at http://cancercontrol.cancer.gov/mli/index.htm

  • May 5, 2011

    Multilevel Interventions in Health Care Conference: Recap of Day 1 by Arnold Kaluzny, PhD (13:27)
    Arnold Kaluzny, PhD (University of North Carolina) welcomes participants to the second day of the Multilevel Interventions in Health Care Conference, sponsored by the National Cancer Institute. He summarizes the first day's events.

    Conference Description
    The research conference sponsored by the National Cancer Institute assembled health care researchers, clinicians, and administrators to discuss the importance of multilevel approaches to improving health care quality in the United States. It occurred over two days and was associated with the American Society for Preventive Oncology's (ASPO) annual meeting in March of 2011.

    This presentation is one of 13 research papers. The conference offered platforms for participant discussion and engagement regarding the opportunities and challenges of multilevel intervention research. Recorded sessions, presentation slides, and additional resources are available at http://cancercontrol.cancer.gov/mli/index.htm

  • May 5, 2011

    Multilevel Interventions in Health Care Conference: Keynote address by W. Richard Scott, PhD (37:19)
    Multilevel Interventions in Health Care: Building the Foundation for Future Research Goals

    Dr. Richard Scott's (Stanford University) keynote address on the first day of the conference presents conceptual issues and the opportunities for multilevel research. Arnold Kaluzny introduces Dr. Scott.

    Conference Description
    The research conference sponsored by the National Cancer Institute assembled health care researchers, clinicians, and administrators to discuss the importance of multilevel approaches to improving health care quality in the United States. It occurred over two days and was associated with the American Society for Preventive Oncology's (ASPO) annual meeting in March of 2011.

    This presentation is one of 13 research papers. The conference offered platforms for participant discussion and engagement regarding the opportunities and challenges of multilevel intervention research. Recorded sessions, presentation slides, and additional resources are available at http://cancercontrol.cancer.gov/mli/index.htm

  • May 5, 2011

    Multilevel Interventions in Health Care Conference: Q&A session moderated by Ellen Gritz, PhD (31:51)
    Multilevel Interventions in Health Care: Building the Foundation for Future Research Goals

    Dr. Gritz (University of Texas MD Anderson Cancer Center), the moderator for Section II Papers, entertains questions and comments from conference participants and engages the panel of presenters in discussion of the issues covered in their papers.

    Conference Description
    The research conference sponsored by the National Cancer Institute assembled health care researchers, clinicians, and administrators to discuss the importance of multilevel approaches to improving health care quality in the United States. It occurred over two days and was associated with the American Society for Preventive Oncology's (ASPO) annual meeting in March of 2011.

    This presentation is one of 13 research papers. The conference offered platforms for participant discussion and engagement regarding the opportunities and challenges of multilevel intervention research. Recorded sessions, presentation slides, and additional resources are available at http://cancercontrol.cancer.gov/mli/index.htm

  • May 5, 2011

    Multilevel Interventions in Health Care Conference: Discussant comments by Brian Mittman, PhD (12:31)
    Dr. Mittman (United States Department of Veterans Affairs), the section discussant, comments on the issues presented from papers by Drs. Morrissey and Charns on the first day of the conference.

    Conference Description
    The research conference sponsored by the National Cancer Institute assembled health care researchers, clinicians, and administrators to discuss the importance of multilevel approaches to improving health care quality in the United States. It occurred over two days and was associated with the American Society for Preventive Oncology's (ASPO) annual meeting in March of 2011.

    This presentation is one of 13 research papers. The conference offered platforms for participant discussion and engagement regarding the opportunities and challenges of multilevel intervention research. Recorded sessions, presentation slides, and additional resources are available at http://cancercontrol.cancer.gov/mli/index.htm

  • May 5, 2011

    Multilevel Interventions in Health Care Conference: Presentation by Martin Charns, DBA (16:33)
    Multilevel Interventions in Health Care: Building the Foundation for Future Research Goals

    Multilevel Interventions: Measurement and Measures Lead author: Martin Charns, DBA (Boston University; United States Department of Veterans Affairs)

    The purpose of this paper is to explore the issues/opportunities related to measurement when planning, developing, and implementing multilevel interventions across the cancer care continuum. Specifically, the paper will discuss ways to think about measurement when operating in a multi-phase (i.e., cancer care continuum), multilevel (e.g., patient, provider, delivery environment) service (i.e., cancer care, health care) delivery environment.

    Conference Description
    The research conference sponsored by the National Cancer Institute assembled health care researchers, clinicians, and administrators to discuss the importance of multilevel approaches to improving health care quality in the United States. It occurred over two days and was associated with the American Society for Preventive Oncology's (ASPO) annual meeting in March of 2011.

    This presentation is one of 13 research papers. The conference offered platforms for participant discussion and engagement regarding the opportunities and challenges of multilevel intervention research. Recorded sessions, presentation slides, and additional resources are available at http://cancercontrol.cancer.gov/mli/index.htm

  • May 5, 2011

    Multilevel Interventions in Health Care Conference: Presentation by Joseph Morrissey, PhD (13:54)
    Multilevel Interventions in Health Care: Building the Foundation for Future Research Goals

    Computer Simulation Models and Multilevel Cancer Control Interventions Lead author: Joseph Morrissey, PhD (University of North Carolina at Chapel Hill)

    This paper will examine how models can be used to simulate the effects of multilevel intervention components and the role of mediating and moderating factors on outcomes. The paper will: (a) describe how simulation has been used to assess intervention effects outside of the realm of cancer; (b) propose extensions of existing models of the natural history of cancer and cancer care; and (c) discuss challenges and future directions for simulation modeling in cancer control.

    Conference Description
    The research conference sponsored by the National Cancer Institute assembled health care researchers, clinicians, and administrators to discuss the importance of multilevel approaches to improving health care quality in the United States. It occurred over two days and was associated with the American Society for Preventive Oncology's (ASPO) annual meeting in March of 2011.

    This presentation is one of 13 research papers. The conference offered platforms for participant discussion and engagement regarding the opportunities and challenges of multilevel intervention research. Recorded sessions, presentation slides, and additional resources are available at http://cancercontrol.cancer.gov/mli/index.htm

  • May 5, 2011

    Multilevel Interventions in Health Care Conference: Discussant comments by Thomas Vogt, MD, MPH (10:28)
    Dr. Vogt, the section discussant, comments on the issues presented from papers by Drs. Weiner, Alexander, and Cleary on the first day of the conference.

    Conference Description
    The research conference sponsored by the National Cancer Institute assembled health care researchers, clinicians, and administrators to discuss the importance of multilevel approaches to improving health care quality in the United States. It occurred over two days and was associated with the American Society for Preventive Oncology's (ASPO) annual meeting in March of 2011.

    This presentation is one of 13 research papers. The conference offered platforms for participant discussion and engagement regarding the opportunities and challenges of multilevel intervention research. Recorded sessions, presentation slides, and additional resources are available at http://cancercontrol.cancer.gov/mli/index.htm

  • May 5, 2011

    Multilevel Interventions in Health Care Conference: Presentation by Paul Cleary, PhD (10:22)
    Multilevel Interventions in Health Care: Building the Foundation for Future Research Goals Multilevel Interventions: Study Design and Analysis Issues Lead author: Paul Cleary, PhD (Yale University) This paper will discuss approaches to studying multilevel interventions across the cancer care continuum, and in other therapeutic areas. The paper will reference existing reviews of the statistical issues and discuss the strengths and weaknesses of available study designs using examples where possible. Conference Description The research conference sponsored by the National Cancer Institute assembled health care researchers, clinicians, and administrators to discuss the importance of multilevel approaches to improving health care quality in the United States. It occurred over two days and was associated with the American Society for Preventive Oncology's (ASPO) annual meeting in March of 2011. This presentation is one of 13 research papers. The conference offered platforms for participant discussion and engagement regarding the opportunities and challenges of multilevel intervention research. Recorded sessions, presentation slides, and additional resources are available at http://cancercontrol.cancer.gov/mli/index.htm

  • May 5, 2011

    Multilevel Interventions in Health Care Conference: Presentation by Jeff Alexander, PhD (08:10)
    Multilevel Interventions in Health Care: Building the Foundation for Future Research Goals

    Time Issues in Multi-level Interventions for Cancer Treatment and Prevention Lead author: Jeff Alexander, PhD (University of Michigan)

    This paper will explore how time (and timing) introduces important complexities in the design of multilevel interventions and in modeling behavior and expected results of such interventions. The paper will address: a) time as a level embedded within individual patients; b) temporal aspects of intervention implementation, fidelity, and sustainability; c) analytic techniques for incorporating time in models of multilevel interventions, and d) costs and benefits of incorporating time in evaluations of multilevel interventions.

    Conference Description
    The research conference sponsored by the National Cancer Institute assembled health care researchers, clinicians, and administrators to discuss the importance of multilevel approaches to improving health care quality in the United States. It occurred over two days and was associated with the American Society for Preventive Oncology's (ASPO) annual meeting in March of 2011.

    This presentation is one of 13 research papers. The conference offered platforms for participant discussion and engagement regarding the opportunities and challenges of multilevel intervention research. Recorded sessions, presentation slides, and additional resources are available at http://cancercontrol.cancer.gov/mli/index.htm

  • May 5, 2011

    Multilevel Interventions in Health Care Conference: Presentation by Brian Weiner, PhD (11:33)
    Multilevel Interventions in Health Care: Building the Foundation for Future Research Goals

    In Search of Synergy: Strategies for Combining Interventions at Multiple Levels Lead author: Brian Weiner, PhD (University of North Carolina at Chapel Hill)

    The social ecological perspective provides a compelling justification for multilevel intervention. Yet it offers little guidance for selecting interventions that work together in complementarity or synergistic ways. Using a causal modeling framework, we describe five strategies for increasing potential complementary or synergy among interventions that operate at different levels of influence.

    Conference Description
    The research conference sponsored by the National Cancer Institute assembled health care researchers, clinicians, and administrators to discuss the importance of multilevel approaches to improving health care quality in the United States. It occurred over two days and was associated with the American Society for Preventive Oncology's (ASPO) annual meeting in March of 2011.

    This presentation is one of 13 research papers. The conference offered platforms for participant discussion and engagement regarding the opportunities and challenges of multilevel intervention research. Recorded sessions, presentation slides, and additional resources are available at http://cancercontrol.cancer.gov/mli/index.htm

  • May 5, 2011

    Multilevel Interventions in Health Care Conference: Q&A session moderated by Rena Pasick, DrPH (30:46)
    Multilevel Interventions in Health Care: Building the Foundation for Future Research Goals

    Dr. Pasick (University of California, San Francisco), the moderator for Introduction Papers, entertains questions and comments from conference participants and engages the panel of presenters in discussion of the issues covered in their papers.

    Conference Description
    The research conference sponsored by the National Cancer Institute assembled health care researchers, clinicians, and administrators to discuss the importance of multilevel approaches to improving health care quality in the United States. It occurred over two days and was associated with the American Society for Preventive Oncology's (ASPO) annual meeting in March of 2011.

    This presentation is one of 13 research papers. The conference offered platforms for participant discussion and engagement regarding the opportunities and challenges of multilevel intervention research. Recorded sessions, presentation slides, and additional resources are available at http://cancercontrol.cancer.gov/mli/index.htm

  • May 5, 2011

    Multilevel Interventions in Health Care Conference: Discussant comments by Maria Fernandez, PhD (12:22)
    Multilevel Interventions in Health Care: Building the Foundation for Future Research Goals

    Dr. Fernandez (University of Texas), the section discussant, comments on the issues presented from papers by Drs. Taplin, Zapka, and Stange on the first day of the conference.

    Conference Description
    The research conference sponsored by the National Cancer Institute assembled health care researchers, clinicians, and administrators to discuss the importance of multilevel approaches to improving health care quality in the United States. It occurred over two days and was associated with the American Society for Preventive Oncology's (ASPO) annual meeting in March of 2011.

    This presentation is one of 13 research papers. The conference offered platforms for participant discussion and engagement regarding the opportunities and challenges of multilevel intervention research. Recorded sessions, presentation slides, and additional resources are available at http://cancercontrol.cancer.gov/mli/index.htm

  • May 5, 2011

    Multilevel Interventions in Health Care Conference: Presentation by Kurt Stange, MD, PhD (10:59)
    Multilevel Interventions in Health Care: Building the Foundation for Future Research Goals

    State-of-the-Art and Future Directions in Multilevel Interventions Across the Cancer Control Continuum Lead author: Kurt Stange, MD, PhD (Case Western Reserve University)

    This paper will describe the current state of multilevel cancer control intervention research, characterize how multilevel research currently is conceptualized and implemented, and identify opportunities to advance cancer control through multilevel research.

    Conference Description
    The research conference sponsored by the National Cancer Institute assembled health care researchers, clinicians, and administrators to discuss the importance of multilevel approaches to improving health care quality in the United States. It occurred over two days and was associated with the American Society for Preventive Oncology's (ASPO) annual meeting in March of 2011.

    This presentation is one of 13 research papers. The conference offered platforms for participant discussion and engagement regarding the opportunities and challenges of multilevel intervention research. Recorded sessions, presentation slides, and additional resources are available at http://cancercontrol.cancer.gov/mli/index.htm

  • May 5, 2011

    Multilevel Interventions in Health Care Conference: Presentation by Jane Zapka, ScD (10:08)
    Multilevel Factors Impacting Quality: Examples from the Cancer Care Continuum Lead author: Jane Zapka, ScD (Medical University of South Carolina)

    The purpose of this paper is to use case scenarios representing two types of care (screening and survivorship) to: a) illustrate the variability, diversity, and interaction of factors from multiple levels that impact the quality of care delivery across the cancer continuum; and b) discuss implications for research and provide examples of multilevel interventions. The overall goal of such interventions is to have a positive impact on care as indicated by the characteristics of quality care, and ultimately affect morbidity and mortality.

    Conference Description
    The research conference sponsored by the National Cancer Institute assembled health care researchers, clinicians, and administrators to discuss the importance of multilevel approaches to improving health care quality in the United States. It occurred over two days and was associated with the American Society for Preventive Oncology's (ASPO) annual meeting in March of 2011.

    This presentation is one of 13 research papers. The conference offered platforms for participant discussion and engagement regarding the opportunities and challenges of multilevel intervention research. Recorded sessions, presentation slides, and additional resources are available at http://cancercontrol.cancer.gov/mli/index.htm

  • May 5, 2011

    Multilevel Interventions in Health Care Conference: Introduction by Stephen Taplin, MD, MPH (18:02)
    Multilevel Interventions in Health Care: Building the Foundation for Future Research Goals

    Introduction: Understanding and Influencing Multilevel Factors Across the Cancer Continuum Lead author: Stephen Taplin, MD, MPH (National Cancer Institute) This overview paper will provide frameworks and definitions to lay the groundwork for subsequent articles on multilevel interventions and research on the cancer care continuum.

    Conference Description
    The research conference sponsored by the National Cancer Institute assembled health care researchers, clinicians, and administrators to discuss the importance of multilevel approaches to improving health care quality in the United States. It occurred over two days and was associated with the American Society for Preventive Oncology's (ASPO) annual meeting in March of 2011.

    This presentation is one of 13 research papers. The conference offered platforms for participant discussion and engagement regarding the opportunities and challenges of multilevel intervention research. Recorded sessions, presentation slides, and additional resources are available at http://cancercontrol.cancer.gov/mli/index.htm

  • May 5, 2011

    Multilevel Interventions in Health Care Conference: Overview by Arnold Kaluzny, PhD (13:10)
    Multilevel Interventions in Health Care: Building the Foundation for Future Research Goals

    Arnold Kaluzny, PhD (University of North Carolina), provides an overview of the Multilevel Interventions in Health Care Conference. He is introduced by Steven Clauser, PhD (National Cancer Institute).

    Conference Description
    The research conference sponsored by the National Cancer Institute assembled health care researchers, clinicians, and administrators to discuss the importance of multilevel approaches to improving health care quality in the United States. It occurred over two days and was associated with the American Society for Preventive Oncology's (ASPO) annual meeting in March of 2011.

    This presentation is one of 13 research papers. The conference offered platforms for participant discussion and engagement regarding the opportunities and challenges of multilevel intervention research. Recorded sessions, presentation slides, and additional resources are available at http://cancercontrol.cancer.gov/mli/index.htm

  • April 27, 2011

    African American Men and Oral Cancer (3:10)
    African American men are one of the groups at highest risk for oral cancer - but many don't know it. Watch this video to learn more about oral cancer and the importance of detecting the disease early when it can be treated more successfully. Brought to you by the National Institute of Dental and Craniofacial Research (NIDCR).

  • April 20, 2011

    Multilevel Interventions in Health Care Conference: Welcome by Steven Clauser, PhD (6:07)
    Multilevel Interventions in Health Care: Building the Foundation for Future Research Goals
    Steven Clauser, PhD (NCI), welcomes participants to the first day of the Multilevel Interventions in Health Care Conference, sponsored by the National Cancer Institute.

    Conference Description
    The research conference sponsored by the National Cancer Institute assembled health care researchers, clinicians, and administrators to discuss the importance of multilevel approaches to improving health care quality in the United States. It occurred over two days and was associated with the American Society for Preventive Oncology's (ASPO) annual meeting in March of 2011.

    This presentation is one of 13 research papers. The conference offered platforms for participant discussion and engagement regarding the opportunities and challenges of multilevel intervention research. Recorded sessions, presentation slides, and additional resources are available at http://cancercontrol.cancer.gov/mli/index.htm

  • April 12, 2011

    NIH Artificial Heart Valve (3:46)
    The DeWitt Stetten Medical Museum participated in a AAAS Webinar aired on April 1, 2011. The Stetten Museum showed and explained the early use of heart valve surgery at the National Institutes of Health.

  • April 6, 2011

    Strategic Plan for NIH Obesity Research (4:18)
    Dr. Francis Collins, director of the National Institutes of Health, talks about the importance of obesity research and the Strategic Plan for NIH Obesity Researc

  • March 29, 2011

    "i on NIH" - April 2011 vodcast (21:16)
    Featured in this month's episode are segments about a spina bifida study, the Heart Truth, and dry eye.

  • March 17, 2011

    Cataract (2:35)
    A doctor explains cataract and how to prevent and treat the condition.

  • February 10, 2011

    Management of Myelomeningocele Study (MOMS) (4:35)
    Spina bifida is an open spinal cord, and myelomeningocele is he most severe form of spina bifida. Dr. Catherine Spong of the National Institute of Child Health and Health Development discusses the result of a trial undertaken to evaluate whether or not prenatal surgery for spina bifida was beneficial compared to the standard postnatal repair.

  • February 5, 2011

    Recovery of photographs after a water emergency (1:03)
    This video describes techniques for salvaging small color snapshots that have been wet for a short time before the surface has become mushy, moldy or damaged. The surfaces of color snapshots and many older historic photos are easily damaged after being wet—avoid touching the front of the photograph. If the photos are already stuck to plastic album pages, do not remove—drain off any excess water from the plastic pages and allow to air dry. Rinsing with a strong water stream or wiping with a soft brush may cause more damage to photos that have a soft mushy surface. When in doubt, just briefly immerse the photo in a tub of clean water, allow the excess water to drain off, then dry the photos as described by laying flat or hanging.

  • January 21, 2011

    Liver-2 (0:13)
    Vascular flow (Cascade Blue Dextran, blue) in the liver of a transgenic mouse expressing soluble GFP (Hepatocytes, green) and membrane-targeted Tomato (Cellular membranes, red). Imaging performed by intravital confocal microscopy

  • January 21, 2011

    Migration (0:12)
    Macrophages migrating in a tumor implanted in the back of an immunocompromised mouse and imaged by intravital two-photon microscopy. The tissue is labeled by injection of Hoechst (cyan) to label the nuclei

  • January 21, 2011

    Endocytosis-3 (0:30)
    Trafficking of dextrans in the endosomal compartment in the Salivary glands of live rats. In red Texas Red-Dextran accumulated in lysosomes. In green internalization and endosomal fusion of Alexa-488 Dextran.

  • January 21, 2011

    Liver (0:10)
    Vascular flow in the liver of a live rat imaged by using intra-vital microscopy. In red, Texas-Red Dextran, in cyan the hepatocytes revealed by endogenous fluorescence

  • January 21, 2011

    Endocytosis-1 (0:17)
    Systemic injection of 70 KDa Texas Red-Dextran and 500 KDa FITC-Dextran in a live rat. Texas Red-dextran internalization in the stromal cells of the Salivary Glands is imaged using intravital two-photon microscopy.

  • January 21, 2011

    The Heart Truth (12:18)
    To warn us about our number one killer and inspire us to take action against it, the National Heart, Lung, and Blood Institute—NHLBI—created the "Heart Truth," a national awareness campaign for women about heart disease. At community events through local programming throughout the country, the campaign encourages us to know the risk for heart disease and make changes to achieve heart health for ourselves and our families. The centerpiece of the "Heart Truth" is the red dress, which was introduced by NHLBI as the national symbol for women and heart disease. The red dress is a red alert for women to take action and take care of their hearts at all ages.

  • January 12, 2011

    Age-Related Macular Degeneration (2:05)
    A doctor explains age-related macular degeneration.

  • January 4, 2011

    Glaucoma (2:16)
    A doctor explains glaucoma, and how to treat the condition.

  • January 3, 2011

    Severe Asthma Research at the National Heart, Lung, and Blood Institute (6:18)
    This presentation discusses research aimed at developing new treatments for patients with severe asthma being conducted at the National Institutes of Health's National Heart, Lung, and Blood Institute.

  • January 3, 2011

    Diabetic Eye Disease (2:09)
    A doctor explains diabetic eye disease, and how to treat the condition.

Videos from NIH: 2010

  • December 14, 2010

    Dry Eye (1:38)
    A doctor explains dry eye and how to treat the condition.

  • November 29, 2010

    AIDSinfo—Top 10 in 2010 (6:20)
    In observance of World AIDS Day 2010, AIDSinfo is pleased to announce the premier of a video highlighting AIDSinfo services entitled "AIDSinfo — Top 10 in 2010." AIDSinfo is your source for federally approved HIV treatment and research information.

  • November 26, 2010

    NIAMS and the American Recovery and Reinvestment Act (ARRA) (3:50)
    The American Recovery and Reinvestment Act (ARRA) resulted in an infusion of funds for NIH research, and provided the NIAMS with significant opportunities to impact research related to conditions of the bones, joints, muscles, and skin.

  • November 22, 2010

    NIH Summer Employment Program (0:30)
    Summer employees discuss the NIH Summer Employment Program

  • November 22, 2010

    Applying to the NIH Summer Internship Program (14:45)
    Dr. Sharon Milgram, the director of the NIH Office of Intramural Training and Education, discusses how to apply for the NIH Summer Internship Program.

  • November 15, 2010

    Key Enzyme Gene Variations Linked to Prostate Cancer (6:26)
    Recently, researchers at the National Institutes of Health reported that variations in a gene for an enzyme involved in cell energy metabolism appear to increase the risk for prostate cancer. The genetic variations all impair the enzyme phosphodiesterase 11A (PDE11A), which helps regulate a cell's responses to hormones and other signals. Previous studies by this group have linked genetic variations that inactivate PDE11A with increased susceptibility to testicular cancer and adrenal tumors. In a new Web video, the study's senior author, Constantine Stratakis, M.D., D.Sc., acting director of the Intramural Research program at the NICHD, discusses the study's findings

  • October 25, 2010

    Movement of epithelial cells in developing gland (0:21)
    Dr. Jeff Chi-feng Hsu of the National Institute of Dental and Craniofacial Research discusses a method he devised to watch the movement of epithelial cells in the developing gland labeled with green fluorescent protein

  • October 25, 2010

    Overview of gland (0:30)
    Dr. Jeff Chi-feng Hsu of the National Institute of Dental and Craniofacial Research devised a method to watch the movement of epithelial cells in the developing gland labeled with green fluorescent protein. Using a red dye to identify spaces between cells, he could directly follow how the clefts formed. Here is a time lapse video of the cleft process in the salivary gland and the branching of new tissue.

  • October 20, 2010

    The NIH Common Fund, To Boldly Go Where No Robot Has Gone Before (6:55)
    To Boldly Go Where No Robot Has Gone Before: An Interview with Dr. Chris Austin, Director, NIH Chemical Genomics Center, Molecular Libraries Program

  • October 18, 2010

    Los Chicos del Cohete (3:28)
    Vean como la juventud y la ciencia pueden hacer florecer la ciencia en esta historia verídica de dos jovencitos que iniciaron exitosamente un proyecto científico gracias a una beca obtenida de los Institutos Nacionales de Salud (NIH) en 1957.

    El Centro de Revisión Científica del NIH preparó este video para estimular el interés de la juventud por la ciencia y demostrar el poderoso impacto del NIH en el avance de la ciencia y de la salud.

    El libro del NIH, "Los "Chicos del Cohete" (Rocket Boys of NIH), fotos y videos se encuentran en nuestro enlace electrónico http://www.csr.nih.gov/rocket.

    Maestros, estudiantes, periodistas y otras organizaciones sin fines lucrativos, pueden usar el video sin restricciones.

    Contacte CSRCommunicationsoffice@csr.nih.gov si tiene preguntas.

  • October 18, 2010

    The Rocket Boys of NIH (3:32)
    See how kids and science can soar in this true story of two kids launched into a scientific adventure after getting a "grant" from the National Institutes of Health in 1957.

    The NIH Center for Scientific Review designed this video to engage young people in science and show the powerful way NIH advances science and health.

    View the Rocket Boys of NIH book, photos, other videos on our Web site: http://www.csr.nih.gov/rocket/

    Teachers, students, broadcasters, webmasters and non-profit organizations may show this video without restrictions. You can download the video files from our Web site.

    Contact us if you have questions: CSRCommunicationsOffice@csr.nih.gov

  • October 7, 2010

    Vision Process Overview (5:01)
    Throughout the coming year, the National Institute of Child Health and Human Development (NICHD) will collaborate with its many stakeholders to identify the most promising scientific opportunities of the next decade across the breadth of the Institute's mission. The aim of this process is to develop a scientific Vision that sets an ambitious agenda and inspires the NICHD, its many partners, and the research community to achieve critical scientific goals and meet pressing public health needs.

  • October 6, 2010

    Dilated Eye Exam (2:19)
    Dr. Rachel Bishop of the National Eye Institute discusses the importance of having a dilated eye exam.

  • October 5, 2010

    Filtration of a fluorescent dye through the kidney of a live rat (0:12)
    Filtration of a fluorescent dye through the kidney of a live rat imaged by using intra-vital microscopy. In red, a fluorescent dye that flows first through the distal and then to the proximal tubuli (both highlighted in green). The movie is played at 50X the real speed.

  • October 5, 2010

    Vascular flow close to a lymph node in a live mouse harboring a metastatic tumor (0:08)
    Vascular flow close to a lymph node in a live mouse harboring a metastatic tumor imaged by using intra-vital microscopy. Red blood cells and leucocytes are shown in black. In green, two tumoral cells in the process of entering the vasculature. The movie is played at 25X the real speed.

  • October 5, 2010

    Cross section of a large vein in a live mouse (0:07)
    Cross section of a large vein in a live mouse imaged by using intra-vital microscopy. Circulating blood cells flowing through the vessel are shown in black. The movie is played at 9X the real speed.

  • September 17, 2010

    NIH and NASA collaborate on International Space Station.mp4 (4:22)
    The NIH and NASA have a strong history of collaboration and share many interests in the life and health sciences. The two agencies recently partnered to conduct biomedical experiments that astronauts could perform on the International Space Station (ISS).

  • September 16, 2010

    ADHD: Attention Deficit Hyperactivity Disorder (4:11)
    Researchers from the National Institute of Mental Health, part of the National Institutes of Health, talk about the symptoms of ADHD as well as the latest research.

  • September 8, 2010

    The NIH Osteoarthritis Initiative (3:06)
    The NIH Osteoarthritis Initiative (OAI) focuses on the most common form of osteoarthritis, knee OA. A public repository was developed that is used by scientists throughout the world to further the development of osteoarthritis drugs and to improve public health.

  • September 8, 2010

    NIAMS Information Dissemination and Outreach (1:55)
    An important part of the NIAMS mission is to support the dissemination of information on research progress related to arthritis and musculoskeletal and skin diseases

  • September 8, 2010

    Genetic Risk Factor for Rheumatoid Arthritis and Lupus (2:26)
    A longtime collaborative research program has identified a genetic variation that increases the risk of two autoimmune diseases: rheumatoid arthritis (RA), and systemic lupus erythematosus, or lupus.

  • September 8, 2010

    The DIRA Discovery (3:49)
    NIAMS researchers recently discovered a new autoinflammatory syndrome - deficiency of the interleukin-1 receptor antagonist (DIRA), through innovative and collaborative efforts with an international team of investigators.

  • September 8, 2010

    The NIAMS Coalition (2:25)
    The NIAMS Coalition plays a vital role as a liaison among the researchers that NIAMS funds, the patients who benefit from the Institute's research investments, Congress and the general public.

  • September 8, 2010

    NIAMS Career Development and Training (1:45)
    NIAMS is dedicated to training a new generation of scientists to solve the health problems within the Institute's research mandate. We actively seek candidates at all stages in their careers who want to learn the latest advances in basic and clinical research

  • September 8, 2010

    Bone Mass in Children and Adolescents (1:50)
    A recent study funded by NIAMS sheds light on the development of bone mass in children and adolescents. It suggests that bone mass may actually peak earlier than is currently believed.

  • September 8, 2010

    Biomedical Research on the International Space Station (2:54)
    NIH is working closely with NASA to facilitate biomedical research in space for better understanding of human health on earth.

  • September 8, 2010

    The APPLE Trial (2:40)
    Learn about the Atherosclerosis Prevention in Pediatric Lupus Erythematosus, or APPLE Trial—a collaborative effort between NIAMS and the Childhood Arthritis and Rheumatology Research Alliance (CARRA) to study the effects of a common cholesterol drug against artery fat buildup in children with lupus

  • September 2, 2010

    Dr. Howard Nash (18:03)
    The Howard Nash Symposium
    Recognizing 40 years of Contributions to Genetics Research
    NIH Symposium August 9, 2010

  • August 26, 2010

    The NIH Common Fund's Human Microbiome Project (6:11)
    No Longer Germ Warfare. An interview with Dr. Julie Segre, NIH Intramural Researcher, The NIH Common Fund's Human Microbiome Project.

  • August 9, 2010

    The Heart Truth ® (La verdad acerca del corazón) (Spanish language with Spanish captions) (11:51)
    La enfermedad del carazón es la causa principal de muerte entre las mujeres en los Estados Unidos, incluso entre las hispanas. Una de cada cuatro mujeres muere por la enfermedad del corazón. Con el fin de alterarnos sobre esta grave amenaza para la salud, el Instituto Nacional de Carozón, loas Pulmones y la Sangre (NHLBI por sus siglas en ingles) ha creado él vestido rojo como el simbolo nacional de la campana para concientizarnos sobre la enfernedad del corazón en las mujeres. El vestido rojo es el elemento central de la campana nacional de NHLBI. La verdad acerca del corazón, conocida en ingles como The Heart Truth.

  • August 9, 2010

    The Heart Truth ® (La verdad acerca del corazón) (Spanish language with English captions).f4v (11:52)
    every four women dies of heart disease. To alert women to this serious health threat, the National Heart, Lung, and Blood Institute (NHLBI) has chosen the red dress as the national symbol for women and heart disease awareness. The Red Dress is the centerpiece of NHLBI's national campaign 'The Truth About the Heart,' known in English as The Heart Truth.

    Heart disease is the number one killer of women in the United States, even among Hispanics. One out of every four women dies of heart disease. To alert women to this serious health threat, the National Heart, Lung, and Blood Institute (NHLBI) has chosen the red dress as the national symbol for women and heart disease awareness. The Red Dress is the centerpiece of NHLBI's national campaign 'The Truth About the Heart,' known in English as The Heart Truth.

  • July 29, 2010

    The National Institutes of Health - 1965 (24:15)
    This is a 1965 overview video about the National Institutes of Health in Bethesda, Maryland. For more information about the NIH visit: www.nih.gov

  • June 30, 2010

    Translational Research and Vision (5:56)
    National Eye Institute 40th Anniversary
    Translational Research and Vision
    Francis Collins, M.D., Ph.D
    Director, National Institutes of Health

  • June 16, 2010

    NIH Tips for Applicants (4:38)
    NIH Tips for Applicants: Reviewers and staff at the National Institutes of Health offer their insights to scientists seeking to improve their chances of getting a grant from the National Institutes of Health.

    The NIH Center for Scientific Review created this video as a companion to its NIH Peer Review Revealed video, which features real scientists reviewing fictional but realistic grant applications.

    Learn more at our video Web page: http://www.csr.nih.gov/video/video.asp

  • June 14, 2010

    NIH Tips for Applicants (4:38)
    NIH Tips for Applicants: Reviewers and staff at the National Institutes of Health offer their insights to scientists seeking to improve their chances of getting a grant from the National Institutes of Health.

  • June 4, 2010

    Diabetic Macular Edema (6:31)
    Researchers have shown that ranibizumab eye injections, often in combination with laser treatment, result in better vision than laser treatment alone for diabetes-associated swelling of the retina.

  • June 4, 2010

    Retinopathy of Prematurity (3:18)
    Scientists have shown that through an eye exam, doctors can identify infants who are most likely to benefit from early treatment for a potentially blinding eye condition called retinopathy of prematurity (ROP), resulting in better vision for many children.

  • June 2, 2010

    National Institutes of Health: BIKE TO WORK DAY (5:12)
    Dr. Francis S. Collins, Director of the National Institutes of Health, addresses NIH employees during "Bike to Work Day."

  • May 19, 2010

    Updates on Therapies for Hairy Cell Leukemia (28:48)
    Dr. Robert Kreitman, chief of the Clinical Immunotherapy Section, Laboratory of Molecular Biology at the National Cancer Institute, provides an update on therapies for hairy cell leukemia at an NIH Clinical Center Grands Rounds lecture.

  • May 12, 2010

    Smokefree Women video contest (2:47)
    Smokefree Women is launching a video contest - Celebrating Smokefree Voices. The Smokefree Women's Team want to capture the variety of quitting experiences and reasons for quitting smoking among women and friends/family across the nation.

  • May 12, 2010

    Dual Use Research: A Dialogue (7:40)
    Dual Use Research: A Dialogue This educational video was produced by the National Institutes of Health (U.S. Department of Health and Human Services) to raise awareness and understanding about the issue of dual use life sciences research. The video offers a conceptual introduction to the issue and features interviews with some of the country's leading experts who discuss the need to ensure scientific progress while ensuring appropriate oversight. The target audience includes life scientists, trainees and students, research administrators, and the general public.

  • May 7, 2010

    Link Between Child Care and Academic Achievement and Behavior (3:48)
    Teens who were in high-quality child care settings as young children scored slightly higher on measures of academic and cognitive achievement and were slightly less likely to report acting-out behaviors than peers who were in lower-quality child care arrangements during their early years, according to the latest analysis of a long-running study funded by the National Institutes of Health

  • May 6, 2010

    Higher Oxygen Levels Improve Preterm Survival (5:56)
    New findings from the Eunice Kennedy Shriver National Institute of Child Health and Human Development show that higher oxygen levels improve very preterm infants' survival but increase the risk for a condition that can damage the retina. The study also found that a treatment typically used for adults with sleep apnea also is as effective as the traditional ventilator and surfactant therapy used to treat breathing difficulties in preterm infants—and may result in fewer complications.

  • April 22, 2010

    Women Are Researchers.mp4 (24:19)
    This program looks at three women who overcame gender, ethnic, and physical barriers to become successful biomedical researchers. They serve as inspirational role models and offer advice or preparing for a career in scientific research.

  • March 31, 2010

    Life Works: Veterinarian.mov (2:07)
    Tanya Burkholder, a veterinarian at the National Institutes of Health, discusses her job.

  • March 31, 2010

    Life Works: Recreational Therapist.mov (2:06)
    Mary Carson discusses the importance of recreational therapy and her typical day.

  • March 31, 2010

    Life Works : Registered Nurse.mov (1:56)
    Kelly Richards, a research nurse at the National Institutes of Health who is also a member of the Public Health Service, discusses his typical day and specific protocols his team is working on.

  • March 31, 2010

    Life Works: Emergency Medical Technician.mov (2:07)
    Darryl Lowery, an emergency medical technician with the NIH fire department, discusses his typical work day.

  • March 31, 2010

    Life Works : Ophthalmologist.mov (1:54)
    Dr. Emily Chew, an ophthalmologist at the National Eye Institute, discusses research she is conducting on age-related macular degeneration and diabetic retinopathy, two of the leading causes of blindness. She also talks about her typical work day.

  • March 24, 2010

    Women Are Surgeons.mp4 (25:54)
    This program takes a close up look at the lives of three women surgeons, including an operating room during real-life trauma, heart surgery, and orthopedic surgery.

  • March 24, 2010

    Women Are Pathologists.mp4 (29:47)
    The first part of this program features the fictional story of a teenage girl who learns first-hand about the field of pathology as she tries to resolve a family crisis. The second part of the program features three omen who are real-life pathologists working in forensic pathology, surgical pathology, and academic pathology

  • March 23, 2010

    Women Scientists with Disabilities.mp4 (23:09)
    This program looks at three women scientists who have triumphed over their own challenges to achieve astounding success in their fields.

  • March 23, 2010

    Women in Dental Research (25:23)
    This video looks at three researchers who have contributed to the field of dental research. This segment looks at a community of scientists who banded together to fight an epidemic, how molecular research helps researchers understand the mysteries of oral disease and cancer, and how one scientist has made groundbreaking discoveries about the link between oral health and premature births.

  • March 18, 2010

    Angie Christensen: Forensic Anthropologist.mp4 (1:48)
    Dr. Angie Christensen, a forensic anthropologist at the FBI laboratory, describes what her work entails.

  • March 18, 2010

    Vivian Morales: Medical Technologist.mp4 (1:41)
    Vivian Morales, a medical technologist with the National Institute of Health's Clinical Center, describes what her work entails.

  • March 18, 2010

    Peter Bandettini: Biophysicist.mp4 (1:45)
    Dr. Peter Bandettini, a Biophysicist at the National Institutes of Health, describes what his work entails.

  • March 18, 2010

    Keisha Hines-Harris: Biological Technician.mp4 (2:07)
    Kiesha Hines-Harris, a biological technician at the National Institutes of Health, describes what her work entails.

  • February 24, 2010

    NIH, on the Inside: Gambling Addiction (7:26)
    This episode of "NIH, on the Inside," explores gambling addiction and research being conducted at the National Institutes of Health to understand why teenagers are more likely to take risks.

  • January 22, 2010

    The Science of Simulating Disease Spread (7:41)
    National Institute of General Medical Sciences' program director Irene Eckstrand shares her excitement about the visual and ethical benefits and computer models, the advantage of computer modeling for infectious disease spread, and the future of information integration in computer models.

  • January 12, 2010

    "i on NIH" - January 2010 vodcast (18:50)
    Featured in this month's episode are segments about the tropical disease schistosomiasis, family history's link to type 2 diabetes, and the NIH news update.

  • January 12, 2010

    Schistosomiasis - i on NIH -episode #0024, segment 1 (6:00)
    According to the World Health Organization, at least 200 million people worldwide have the tropical disease schistomiasis and more than 700 million live in endemic areas. This segment looks at a unique resource that is helping investigators learn more about schistomiasis and devise potential ways to end it.

  • January 9, 2010

    Questions to ask about diabetes - i on NIH - episode #0024, segment 2 (04:53)
    In the second of a two-part interview, Dr. Griffin Rodgers, director of the National Institute of Diabetes and Digestive and Kidney Diseases, discusses the risk factors for diabetes as well as a condition called pre-diabetes.

  • January 8, 2010

    NIH research Update - i on NIH—episode #0024, segment 3 (5:11)
    Harrison Wein, Ph.D., discusses a study that indicates that teen fitness may be linked to higher ID and achievement and a study that shows that depriving yourself of certain foods may lead you to overeat.

Videos from NIH: 2009

  • December 2, 2009

    2009 American Recovery and Reinvestment Act: Congenital Heart Defects (3:28)
    Congenital heart defects are the most common type of birth defect, affecting eight out of every 1,000 newborns. The frequency of recurrences in the same families strongly suggests there are genetic contributions. Dr. Edward Lammer, a pediatrician and medical geneticist at Children's Hospital and Research Center in Oakland, California, discusses his research project on congenital heart defects, funded by the National Institutes of Health's National Heart, Lung, and Blood Institute through the 2009 American Recovery and Reinvestment Act.

  • November 12, 2009

    2009 American Recovery and Reinvestment Act: Dr. John W. Lawler (2:35)
    Dr. John W. Lawler, a professor of pathology at Beth Israel Deaconess Medical Center in Boston, Massachusetts, discusses the impact that the 2009 American Recovery and Reinvestment Act has had on his laboratory work on the thrombospondins (a family of extracellar matrix proteins).

  • November 1, 2009

    2009 American Recovery and Reinvestment Act: Dr. Jay Vaidya (1:20)
    Dr. Jay Vaidya of the Johns Hopkins University discusses the impact that the 2009 American Recovery and Reinvestment Act has had on his research on arterial disease.

  • October 29, 2009

    "i on NIH" - October 2009 vodcast (22:13)
    Featured in this month's episode are segments about a 2009 H1N1 influenza update and a discussion about targeted drug delivery.

  • October 23, 2009

    2009 American Recovery and Reinvestment Act: MIT (1:22)
    Researchers from the Massachusetts Institute of Technology discuss how the 2009 American Recovery and Reinvestment Act is helping them develop new technologies for repairing dysfunctional heart muscle tissue.

  • October 23, 2009

    2009 American Recovery and Reinvestment Act: Dr. Pamela Zeitlin (1:14)
    Dr. Pamela Zeitlin, a professor of pediatrics at the Johns Hopkins Children's Center at the Johns Hopkins Hospital in Baltimore, Maryland, discusses the impact that the 2009 American Recovery and Reinvestment Act has had on her research directed at finding an alternative gene as a treatment target for cystic fibrosis.

  • October 23, 2009

    2009 American Recovery and Reinvestment Act: Dr. Clay Marsh (0:59)
    Dr. Clay Marsh, a senior associate vice president for Health Sciences Research at the Ohio State University, discusses the how the 2009 American Recovery and Reinvestment Act has accelerated the time it takes to take a discovery from the laboratory to a patient's bedside.

  • October 23, 2009

    2009 American Recovery and Reinvestment Act: Dr. Kerry Stewart (1:30)
    Dr. Kerry Stewart, professor of Medicine at Johns Hopkins where he directs the clinical and research exercise physiology programs, discusses how the 2009 American Recovery and Reinvestment Act has provided him with the opportunity to hire additional staff to study the overweight and obesity problem in the U.S

  • October 23, 2009

    2009 American Recovery and Reinvestment Act: Lung Cohort Sequencing Project (2:06)
    Researchers at the University of Washington discuss the impact that the 2009 American Recovery and Reinvestment Act will have on the National Heart, Lung, and Blood Institute's Lung Cohort Sequencing Project, a new effort to discover variation in the human genome that influences both acute and chronic diseases.

  • October 22, 2009

    2009 American Recovery and Reinvestment Act: Northwest Genomics Center (2:27)
    Researchers in the Department of Genome Sciences at the University of Washington School of Medicine discuss the impact of the 2009 American Recovery and Reinvestment Act in the establishment of the new Northwest Genomics Center.

  • October 16, 2009

    NIH Research Update - i on NIH—episode #0023, segment 3 (5:22)
    Harrison Wein, Ph.D., discusses three stories related to sleep and circadian rhythm. One is about a gene that regulates sleep length, the second is about sleep and Alzheimer's disease, and the three is about eating when you should be sleeping.

  • October 9, 2009

    2009 Nobel Prize in Physiology or Medicine (1:43)
    Dr. Jeremy Berg, the director of the National Institute of General Medical Sciences at the National Institutes of Health, discusses the 2009 Nobel Prize in Physiology or Medicine that was awarded for the discovery of telomeres and telomerase.

  • October 9, 2009

    2009 Nobel Prize in Chemistry (2:56)
    Dr. Jeremy Berg, the director of the National Institute of General Medical Sciences at the National Institutes of Health, discusses the 2009 Nobel Prize in Chemistry that was awarded for the determination of the high-resolution structure of the ribosome.

  • October 3, 2009

    2009 H1N1 Influenza update (10:01)
    In an interview conducted on September 15, 2009, Dr. Anthony Fauci, the director of the National Institute of Allergy and Infectious Diseases, provided an update of 2009 H1N1 influenza.

  • September 22, 2009

    Modeling the metabolic network of Thermotoga maritima (1:53)
    In the first achievement of it kind, researchers have modeled the structures of every protein involved in Thermotoga maritima, the slowest-evolving bacteria known. Understanding how proteins work in this ancient bacterium could clear up some murky areas in our evolutionary past and teach us more about similar networks in many other animals.

  • September 22, 2009

    Leading Cells with Light (0:57)
    A new light based approach turns on a protein that helps human cancer cells move

  • September 22, 2009

    Findings Videocast - Dr. Omalola Eniola-Adefeso (4:40)
    Dr. Omalola Eniola-Adefeso, a professor of Chemical Engineering at the University of Michigan, discusses the development of a way to deliver drugs right to the part of the body where they're needed to fight infection or disease.

  • September 4, 2009

    Depression (3:51)
    Depression is a serious medial illness; it's not something that you have made up in your head. It's more than just feeling "down in the dumps" or "blue" for a few days. It's feeling "down" and "low" and "helpless" for weeks at a time.

  • August 27, 2009

    NIH Research Update - i on NIH—episode #0022, segment 4 (3:27)
    Updates on a depression gene that may not add to risk after all and scientists pinpoint the cells that give you a light touch.

  • August 27, 2009

    Questions to ask about diabetes - i on NIH - episode #0022, segment 3 (5:59)
    Dr. Griffin Rodgers, director of the National Institute on Diabetes and Digestive and Kidney Diseases, discusses type 2 diabetes

  • August 27, 2009

    NLM's African Malaria tutorial - i on NIH- episode #0022, segment 2 (9:34)
    In part two of a two part interview Julia Royall further discusses the National LIbrary of Medicine's African malaria tutorial and additional planned tutorials.

  • August 27, 2009

    HBO's Alzheimer's Project - i on NIH - episode #0022, segment 1 (9:10)
    The National Institute on Aging recently collaborated with HBO Documentary Films for THE ALZHEIMER'S PROJECT, a multi-platform public health series which takes a look at groundbreaking scientific discoveries and seeks to bring a wider understanding of Alzheimer's disease research and care

  • June 16, 2009

    NIH Research Update - i on NIH - episode #0021, segment 4 (4:06)
    Updates on a new study that shows reveals that our skin is home to a much wider array of bacteria than previously thought and a study that shows that acupuncture and acupuncture-like treatments both improved chronic low back pain.

  • June 16, 2009

    Exercise, Sleep, and Cancer Risk - i on NIH - episode #0021, segment 3 (3:40)
    A study of women examined the link between exercise and cancer risk, paying special attention to whether or not getting adequate sleep further affects the risk of developing cancer.

  • June 16, 2009

    Sudden Cardiac Arrest - in on NIH- episode #0021, segment 2 (3:57)
    Former NFL star and Olympic track and field gold medalist,, Willie Gault, discusses sudden cardiac arrest. Gault is the founder of Athletes for Life, a non-profit organization with a mission to detect and prevent sudden cardiac death.

  • June 16, 2009

    NLM's African malaria tutorial - i on NIH—episode #0021, segment 1 (9:37)
    Julia Royall, chief on international programs, discusses the National Library of Medicine's interactive African malaria tutorial.

  • May 21, 2009

    H1N1 Influenza A virus (4:59)
    Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, discusses the H1N1 influenza A virus.

  • May 18, 2009

    Eye on NEI (1:45)
    A compilation of interviews focusing on Erik Weihenmayer, the only blind man to summit Mount Everest, recounting his experiences with testing a breakthrough vision device known as BrainPort.

  • May 18, 2009

    NEI Interview with Mike Oberdorfer (0:58)
    Michael D. Oberdorfer, Ph.D. at the National Eye Institute explains a new treatment for blindness.

  • May 18, 2009

    NEI Interview with Erik Weihenmayer (2:16)
    Erik Weihenmayer, the only blind man to summit Mount Everest, recounts his experiences with testing a breakthrough vision device known as BrainPort

  • May 18, 2009

    NEI Interview with Bob Beckman (1:42)
    Robert A. Beckman, President and CEO of Wicab, Inc. shares details of how sensory information can be substituted for people who have lost their vision. A device delivers visual information to the tongue.

  • May 14, 2009

    Nanotechnology (1:11)
    Nanotechnology is defined as the understanding and control of matter at dimensions of roughly 1 to 100 nanometers, a scale at which unique properties of materials emerge that can be used to develop novel technologies and products.

  • May 1, 2009

    NIH Research Update - i on NIH -episode #0020, segment 4 (5:09)
    Harrison Wein, Ph.D., discusses the latest research findings from NIH, including a study about fat that could help keep the weight off and what's occupying children with autism.

  • May 1, 2009

    Monitoring the Future Survey - i on NIH - episode #0020, segment 2 (6:29)
    High school senior Lillian Rosen talks to the Director of the National Institute on Drug Abuse, Dr. Nora Volkow, about the latest findings from the most recent annual survey of teen drug abuse - the Monitoring the Future survey.

  • May 1, 2009

    Healthy Vision - i on NIH - episode #0020, segment 1 (6:30)
    May is Healthy Vision Month. Dr. Janine Austin Clayton, an ophthalmologist and deputy director of NIH's Office of Research on Women's Health, discusses the importance of regular eye exams.

  • May 1, 2009

    Neural Tube Defects - i on NIH - episode #0020, segment 3 (3:11)
    A recent study shows that children born to women who have low blood levels of vitamin B-12 shortly before and after conception, may have an increased risk for a neural tube defect.

  • March 31, 2009

    NIH Research Update—i on NIH—episode #0019, segment 4 (5:56)
    No description available.

  • March 31, 2009

    Convergence Insufficiency—i on NIH—episode #0019, segment 3 (4:04)
    NIH-funded researchers have found a more effective treatment for a common childhood eye problem, called convergence insufficiency—or CI.

  • March 31, 2009

    Immature Progenitor Cells—i on NIH—episode #0019, segment 2 (4:05)
    Immature progenitor cells have the unique ability to build brain tissue from a single cell. NIH researchers have discovered how to get these cells in a line, light them up and, using a computer-driven system, split them out.

  • March 31, 2009

    Physical Activity Guidelines—i on NIH—episode #0019, segment 1 (4:22)
    According to the new Physical Activity Guidelines for Americans, adults gain substantial health benefits from from two and a half hours a week of moderate aerobic physical activity, and children benefit from an hour or more of physical activity.

  • March 19, 2009

    NIH Research Update—i on NIH—episode #0018, segment 3 (4:37)
    No description available.

  • March 19, 2009

    Bipolar disorder i on NIH—episode #0018, segment 2 (5:26)
    An in-depth interview with an expert from the National Institute of Mental Health about bipolar disorder.

  • March 19, 2009

    NIH-OXCAM Scholarship Program—i on NIH—episode #0018, segment 1 (7:23)
    The NIH-OXCAM Scholarship Program is an innovative training path for exceptional students in biomedical and research doctoral training.

Videos from NIH: 2008

This page last reviewed on September 27, 2012

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