Randomized Study of the Effects of Glucose on Cognition in Healthy Young and Elderly People and Parkinson's Disease Patients

This study has been completed.
University of Virginia
Information provided by:
National Institute of Mental Health (NIMH)
ClinicalTrials.gov Identifier:
First received: October 18, 1999
Last updated: November 29, 2005
Last verified: November 2005

This study will determine whether glucose facilitates memory in healthy elderly people and those with Parkinson's disease.

Condition Intervention
Parkinson Disease
Drug: Glucose

Study Type: Interventional
Study Design: Allocation: Randomized
Masking: Double-Blind
Primary Purpose: Treatment

Resource links provided by NLM:

Further study details as provided by National Institute of Mental Health (NIMH):

Estimated Enrollment: 120
Study Start Date: March 1998
Detailed Description:

Subjects fast for 8 hours before receiving a test to determine their blood glucose levels. Following this test, subjects are randomized to receive either a glucose or saccharin sweetened drink. A series of memory tests and an additional 3 blood glucose level tests are administered approximately 15 minutes later. A minimum of 1 week afterward, the subjects return and receive the alternate sweetener followed by additional memory tests.


Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Three groups of subjects are eligible for this study: Healthy young adults between ages 18 and 30; Healthy elderly adults between ages 60 and 90; AND Anyone diagnosed with Parkinson's disease

Exclusion Criteria:

  • Prior surgery to remove part of the stomach
  • Diabetes, Addison's, or Cushing's diseases
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00004451

United States, Virginia
University of Virginia
Charlottesville, Virginia, United States, 22908
Sponsors and Collaborators
University of Virginia
Study Chair: Carol A. Manning University of Virginia
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00004451     History of Changes
Other Study ID Numbers: 199/13548, K07 MH01197
Study First Received: October 18, 1999
Last Updated: November 29, 2005
Health Authority: United States: Federal Government

Keywords provided by National Institute of Mental Health (NIMH):
Parkinson disease
neurologic and psychiatric disorders
rare disease

Additional relevant MeSH terms:
Parkinson Disease
Parkinsonian Disorders
Basal Ganglia Diseases
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Movement Disorders
Neurodegenerative Diseases

ClinicalTrials.gov processed this record on September 26, 2012