This issue of The Lancet is dedicated to issues surrounding surgery and traumatic injury. Surgery research includes new estimates of death following general surgery; improved survival after general anaesthetic over the past 50 years; and a new approach to intravenous catheter use, overturning 40 years of accepted practice. Also in this issue, a three-part series on trauma surgery reviews recent progress and challenges in the management of acute trauma care. See the interactive figure on fracture repair pathophysiology and clinical interventions, available on the dedicated page for Surgery and Traumatic Injury.
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Article
Mortality after surgery: National estimates of death following general surgery have been too optimistic, suggests the first large-scale...
Series
Severe traumatic brain injury: despite current progress, traumatic brain injury remains a major global health problem.
Editorial
Non-communicable diseases: the global health movement to tackle NCDs is at a pivotal point.
Article
Meningitis: analysis of national surveillance data to assess the effect of meningococcal A conjugate vaccine on meningitis incidence and...
Article
Human papillomavirus vaccine: comparison of the efficacy of bivalent and quadrivalent vaccines against non-vaccine-type HPV.
Review
Hendra virus: identification, treatment, control, and prevention of Hendra virus in Australia.
Article
Ischaemic stroke: the DEFUSE 2 investigators assess whether MRI diffusion-perfusion mismatch can identify patients who are most likely to...
Review
Reversible cerebral vasoconstriction syndrome: a disorder characterised by severe headaches.
Review
Myotonic dystrophies: a look at clinical and therapeutic challenges for the two genetically distinct types of the disorder.
Article
HannaH study: Gustavo Ismael and colleagues compare the pharmacokinetic profile, efficacy, and safety of subcutaneous versus intravenous...
Article
Vandetanib: a phase 2 trial of this tyrosine kinase inhibitor for patients with advanced or metastatic thyroid cancer.
Breaking news
Medicaid expansion
PTEN cancer and diabetes link
Squamous-cell lung cancer
Barrett's oesophagus
...
About the Journal
The Lancet Respiratory Medicine: will launch in print and online in early 2013, and will be the fourth Lancet specialty journal following...
Breaking News
ERS conference round-up
Supreme Court decision
Whooping cough: cases rise
Vitamin D takes centre-stage
TB care: questioned...
Spotlight
Francesco Blasi: profile
Asthmatics: in film
Sport: Olympic legacy and respiratory diseases
Cathedrals and bazaars...
Article
Drug-eluting stents Sabate and colleagues report the 1-year result of the EXAMINATION trial, comparing everolimus-eluting stents with bare-metal...
Article
Stent thrombosis: dual antiplatelet therapy may be important for patients who have drug-eluting stents implanted.
Article
The PARAMOUNT trial: new drug shows promising results for heart failure patients.
Papers published on The Lancet UK Policy Matters microsite raise concerns about the quality of past evaluations commissioned directly or indirectly by the Department of Health. Read the papers and accompanying blog post to find out more.
UK Policy Matters is a Lancet-based project which explores how UK policy changes affect health. On our microsite you will be able to access evidence-based summaries of different policies and tell us your experiences of how changes in policy have affected health.
If you have evidence of how policy has affected health or health care, we would like to hear from you. We are interested in all forms of evidence, including brief summaries of evidence from academics; and information from the public, managers, and healthcare workers about changes in services and their impact (individual experiences are welcomed).
See the Submit your evidence section of the site to share your experiences and submit your evidence.
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Duration of resuscitation efforts and survival after in-hospital cardiac arrest: an observational study
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The Lancet
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Prevalence of and risk factors for resistance to second-line drugs in people with multidrug-resistant tuberculosis in eight countries: a prospective cohort study
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(2012)
The Lancet
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Safeguarding male circumcision
Editorial
(2012)
The Lancet
380 (9845), p. 860
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Long-term use of standardised ginkgo biloba extract for the prevention of Alzheimer's disease (GuidAge): a randomised placebo-controlled trial
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(2012)
The Lancet Neurology
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Risk of coronary events in people with chronic kidney disease compared with those with diabetes: a population-level cohort study
Article
(2012)
The Lancet
380 (9844), pp. 807-814
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| 1. | Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
Research (1998) Lancet 352 (9131), pp. 837-853
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| 2. | MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20 536 high-risk individuals: A randomised placebo-controlled trial
Research (2002) Lancet 360 (9326), pp. 7-22
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| 3. | Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: Principal results of the Hypertension Optimal Treatment (HOT) randomised trial
Research (1998) Lancet 351 (9118), pp. 1755-1762
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| 4. | Peginterferon alfa-2b plus ribavirin compared with interferonalfa-2b plus ribavirin for initial treatment of chronic hepatitis C: A randomised trial
Research (2001) Lancet 358 (9286), pp. 958-965
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| 5. | A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE)
Research (1996) Lancet 348 (9038), pp. 1329-1339
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AnnouncementsCountdown to 2015: a new two-part Series on Child Equity Health and the 2012 US election: The Lancet captures the debate over the weeks leading up to the November 6 US election. Call for papers: we are inviting submissions for a special issue to coincide with the Women Deliver conference in Kuala Lumpur, Malaysia, on May 28–30, 2013. New Lancet eBooks: The Lancet now publishes eBooks for mobile devices and eReaders. The Lancet Middle East Editorial Page: contraception in the Middle East. New picture quiz gallery: play our picture quizzes and test your medical knowledge and diagnostic skills. |
"The Irish economy has moved from roaring tiger to half-drowned kitten in the space of a few years, with knock-on effects for the health sector."
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"For a large, rural, poorly educated population with no voice of their own, who should demand that they receive evidence-based medicine, if not health-care professionals?"
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"One striking finding was that during a seizure, and sometimes even between seizures, people with epilepsy were sometimes kept in solitary confinement."
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"Establishment of a standard of care for elderly patients with newly diagnosed high-grade glioma would constitute a substantial achievement. On the basis of the NOA-08 trial, this achievement might be realised sooner rather than later."
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A 49-year-old woman with recently diagnosed hypertension, developed sudden onset aphasia and right hemiplegia. A CT of her brain showed a large left subcortical haemorrhage. Dynamic CT-angiography showed dramatic contrast extravasation suggesting ongoing bleeding, and corresponding to rapid neurological deterioration. Our patient had urgent surgical evacuation of the haematoma.
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