The following is a summary of the Solicitation/Request For Proposal (RFP)

Note: Offerors are responsible for reviewing the entire RFP and submitting all information and documentation with their proposal as instructed within the solicitation document.

There are two parts of the proposal that are due, the technical and the business proposal. The RFP is separated into various sections as listed below. Some sections provide information as to what will be required post-contract award, other sections provide information on the proposal process and what is required with the proposal submission. It is very important to review Attachments 1 - 9 carefully as they pertain directly to submission of the proposal. It is also very important to review Sections L. and M. carefully.

Section A. Provides important identifying information (introductory)

Section B. Provides brief description about what services are needed, information on budget, etc...

Section C. Description/Specifications/Work Statement - This refers to Attachment 3 (detailed Statement of Work); provides information on the various reporting requirements that will be applicable post-contract award.

Section D. - Packaging, Marking and Shipping - provides information on post-contract award, e.g. instructions for biomaterials collection

Section E. Inspection and Acceptance - provides information on post-contract award - (deliverables will be reviewed for acceptance)

Section F. - Provides information on post-contract award; e.g. contract deliverables due during performance of any resultant contract

Section G. Contract Administration Data- provides information on post-contract award; required contract administration - e.g. task order procedures, invoicing, key personnel, information security system requirements, etc...

Section H. - Provides information on the special contract requirements that will pertain to any resultant contract, e.g. human subjects, data and safety monitoring, registration of trials, OMB clearance, small business subcontracting matters, information and security matters, conflicts of interest, etc...(post-contract award)

Section I. References general contract clauses (post-contract award)

Section J. (Proposal) Lists the attachments to the RFP and provides links to those that are not physically attached at the end of the RFP.

Section K. Representations and Instructions - (Proposal) discusses one of the steps required if proposal will be submitted

Section L. - (Proposal) Provides Instructions to Offerors for the proposal (both on the development of the technical proposal and of the business proposal

Section M. Evaluation Factors for Award - (Proposal) - Informs of what the peer reviewers will evaluate (technical approach, personnel, etc...)

Abbreviated list of Attachments at end of solicitation document: (Refer to Section J. for complete listing and links) (Proposal)

Attachment 1 - provides instructions about the packaging and delivery instructions of the proposals

Attachment 2 - Is Intent to propose document

Attachment 3 - Statement of Work - discusses the scientific requirements that the Government is seeking

Attachment 4 - Background (scientific)

Attachment 5 - Sample Tasks - (discusses what budgets need to be submitted and the cost assumptions for those; also discusses what protocols need to be submitted)

Attachment 6 - Additional Technical and Business Proposal Instructions - Important to review carefully

Attachment 7 - Past Performance Survey

Attachment 8 - Sample Task Order form

Attachment 9 - Technical Evaluation Criteria (Refer to Section M.)

Concept Review was conducted on January 20, 2012 and concept was approved.

Submit questions in writing to jacobsonmj@mail.nih.gov. Subsequent Amendments will be posted as necessary.

This Solicitation (Request For Proposal) corresponds to the following previously published notices:

Small Business Sources Sought Notice: HHS-NIH-DA-SBSS-12-241, posted on 11/10/11 (previously titled: Small Clinical Trials to Test Feasibility and Specific Target Engagement of Novel Pharmacological Treatments in Autism Disorders (FAST-AS).

Research and Development Sources Sought Notice: HHS-NIH-DA-RDSS-12-241, posted on 11/15/11(previously titled: Small Clinical Trials to Test Feasibility and Specific Target Engagement of Novel Pharmacological Treatments in Autism Disorders (FAST-AS).

Request For Information (RFI): HHS-NIH-DA-RFI-12-001, posted on 12/16/11, Titled: "New Experimental Medicine Studies: Fast-fail trials (FAST)"

Pre-solicitation Notice: HHS-NIH-DA-12-241, posted on 12/22/11, Titled: New Experimental Medicine Studies: Fast-Fail Trials in Autism Spectrum Disorders (FAST-AS)