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6-azauridine
A synthetic triazine analogue of uridine with antimetabolite activity. 6-azauridine inhibits de novo pyrimidine synthesis and DNA synthesis and is converted intracellularly into mono, di-, and triphosphate derivatives, which incorporate into RNA and inhibit protein synthesis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | 6-azauracil riboside azauridine riboazauracil | |
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| Abbreviation: | | 6-AZUR | |
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| Chemical structures: | | 1,2,4-triazine-3,5(2H,4H)-dione, 2-beta-D-ribofuranosyl 2-beta-D-ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione 3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine riboside 6-azauracil-.beta.-D-riboside | |
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