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NCI Drug Dictionary


itraconazole 
A synthetic triazole agent with antimycotic properties. Formulated for both topical and systemic use, itraconazole preferentially inhibits fugal cytochrome P450 enzymes, resulting in a decrease in fungal ergosterol synthesis. Because of its low toxicity profile, this agent can be used for long-term maintenance treatment of chronic fungal infections. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
US brand name:Sporanox
Abbreviation:ICZ