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amonafide dihydrochloride
The dihydrochloride salt of amonafide, an imide derivative of naphthalic acid. Amonafide intercalates into DNA and inhibits topoisomerase II, resulting in protein-associated strand breaks and impaired DNA and RNA synthesis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | amonafide amonafide hydrochloride benzisoquinolinedione nafidimide | |
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| US brand name: | | Quinamed | |
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| Abbreviations: | | AMON BIDA | |
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| Code name: | | M-FA-142 | |
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| Chemical structure: | | 1H-benz(de)isoquinoline-1,3(2H)-dione, 5-amino-2-(2-(dimethylamino)ethyl) | |
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