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NCI Drug Dictionary


tamsulosin hydrochloride 
The hydrochloride salt of tamsulosin, a sulfonamide derivative with adrenergic antagonist activity. Tamsulosin selectivity binds to and blocks the activity of alpha1 adrenoreceptors in the human prostate and bladder neck; blockade of these adrenoceptors can cause smooth muscle in the prostate and bladder neck to relax, resulting in an improvement in urinary flow rate. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
US brand name:Flomax