1.	Phase I Pilot Pharmacokinetic Study of Carboxypeptidase G2 Rescue of High-Dose MTX in Patients with Recurrent Primary CNS Lymphoma Phase: Phase I Type: Supportive care, Treatment Status: Completed Age: 18 and over Sponsor: NCI Protocol IDs: MSKCC-93040, NCI-T92-0244D, T92-0244
2.	Open-label Leucovorin Pharmacokinetic Study in Patients Receiving High Dose Methotrexate With or Without Voraxaze Phase: Phase I Type: Treatment Status: Completed Age: Not specified Sponsor: Pharmaceutical / Industry Protocol IDs: PR001-CLN-pro017, NCT00634504
3.	Trial of Carboxypeptidase-G2 for the Management of Patients With Intrathecal Methotrexate Overdose Phase: No phase specified Type: Supportive care Status: Completed Age: Any age Sponsor: NCI Protocol IDs: NCI-92-C-0137N, CCG-0923, POG-9688, NCI-T92-0021N, COG-0923, COG-P9688, T92-0021, NCT00018967
4.	Study of Carboxypeptidase-G2 and Thymidine in Patients With Methotrexate Toxicity Secondary to Renal Dysfunction (Summary Last Modified 03/2001) Phase: No phase specified Type: Supportive care Status: Completed Age: Any age Sponsor: NCI Protocol IDs: NCI-92-C-0134F, NCI-T92-0022N, T92-0022