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goserelin acetate
The acetate salt of a synthetic decapeptide analog of luteinizing hormone-releasing hormone (LHRH). Continuous, prolonged administration of goserelin in males results in inhibition of pituitary gonadotropin secretion, leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production. (NCI04) Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| US brand name: | | Zoladex | |
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| Abbreviation: | | ZDX | |
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| Code name: | | ICI-118630 | |
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| Chemical structure: | | 6-[O-(1,1-dimethylethyl)-D-serine]-10-deglycinamide luteinizing hormone-releasing factor (pig) 2-(aminocarbonyl)hydrazide | |
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