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decitabine
A cytidine antimetabolite analogue with potential antineoplastic activity. Decitabine incorporates into DNA and inhibits DNA methyltransferase, resulting in hypomethylation of DNA and intra-S-phase arrest of DNA replication. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | 5-aza-dCyd deoxyazacytidine dezocitidine | |
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| US brand name: | | Dacogen | |
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| Abbreviations: | | 5AZA DAC | |
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| Chemical structures: | | 2'-deoxy-5-azacytidine 4-amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one 5-aza-2'-deoxycytidine 5-aza-2-deoxycytidine 5-azadeoxycytidine | |
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