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mesna
A sulfhydryl compound that is used to reduce the incidence of hemorrhagic cystitis associated with certain chemotherapeutic agents. Mesna is converted to a free thiol compound in the kidney, where it binds to and inactivates acrolein and other urotoxic metabolites of ifosfamide and cyclophosphamide, thereby reducing their toxic effects on the urinary tract during urinary excretion. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | mercaptoethane sulfonate Mesnum | |
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| US brand name: | | Mesnex | |
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| Foreign brand names: | | Ausobronc Filesna Mesnil Mexan Mistabron Mistabronco Mitexan Mucofluid Mucolene Uromitexan Ziken | |
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| Abbreviation: | | MSA | |
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| Code names: | | D-7093 UCB 3983 | |
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| Chemical structures: | | 2-mercaptoethanesulfonic acid, sodium salt sodium 2-mercaptoethane sulfonate | |
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