The search textbox has an autosuggest feature. When you enter three or more characters,
a list of up to 10 suggestions will popup under the textbox. Use the arrow keys
to move through the suggestions. To select a suggestion, hit the enter key. Using
the escape key closes the listbox and puts you back at the textbox. The radio buttons
allow you to toggle between having all search items start with or contain the text
you entered in the search box.
mechlorethamine hydrochloride
The hydrochloride salt of mechlorethamine, a nitrogen mustard and an analogue of sulfur mustard, with antineoplastic and immunosuppressive activities. Mechlorethamine is metabolized to an unstable, highly reactive ethyleniminium intemediate that alkylates DNA, particularly the 7 nitrogen of guanine residues, resulting in DNA base pair mismatching, DNA interstrand crosslinking, the inhibition of DNA repair and synthesis, cell-cycle arrest, and apoptosis. This agent also exhibits lympholytic properties. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | chloramin chlorethamine HCl chlorethamine hydrochloride chlorethazine chlorethazine hydrochloride chlormethine chlormethine hydrochloride chloromethine HCl mechlorethamine mechlorethamine HCl methylchlorethamine Mustard mustargen HCl mustargen hydrochloride Mustine NH-2 N-Lost | |
| |||
| US brand name: | | Mustargen | |
| |||
| Foreign brand names: | | Caryolysine Cloramin Erasol Mustine Hydrochloride Onco-Cloramin | |
| |||
| Abbreviations: | | HN 2 NM | |
| |||
| Acronym: | | NM | |
| |||
| Code name: | | WR-147650 | |
| |||
| Chemical structures: | | bis(2-chloroethyl)methylamine ethanamine,2-chloro-N-(2-chloroethyl)-N-methyl methylbis(beta-chloroethyl)amine | |
| |||
