PROGENI: NHLBI Programs in Gene Environment Interactions Network

Program Description

This program was funded from 2002-2006 to identify novel genes which interact with specific environmental exposures to modify risk factors for heart, lung, blood, and sleep (HLBS) disorders. The genetic aspects of response to environmental change, and related biological mechanisms, were studied using short term, focused interventions in families. The goal of this consortium of NHLBI-funded studies was to identify subgroups based on genotype that are most likely to benefit from targeted environmental changes designed to reduce the development or progression of HLBS diseases.

The NHLBI contact for PROGENI is Cashell Jaquish, Ph.D.

Related Websites

Progeni Network: NHLBI GxE Interaction Studies

Comparison of PROGENI Studies

Projects

• GOLDN
• GenSaltv
• GET READI
• Hapi Heart
• Gene Star

Original Funding Announcement (FOA)

Interaction of Genes and Environment in Shaping Risk Factors for Heart, Lung, Blood and Sleep Disorders
RFA-HL-02-010

Last Updated September 2011