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falimarev
A cancer vaccine comprised of a recombinant fowlpox viral vector encoding the carcinoembryonic antigen (CEA), MUC-1, a transmembrane glycoprotein secreted by glandular epithelial tissues, and TRICOM, comprised of three co-stimulatory molecule transgenes (B7-1, ICAM-1 and LFA-3). This agent may enhance CEA and MUC-1 presentation to antigen-presenting cells (APC) and may activate a cytotoxic T-cell response against CEA- and MUC-1-expressing tumor cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | recombinant fowlpox-CEA-MUC-1-TRICOM vaccine rfowlpox-CEA(D609)/MUC1(L93)/TRICOM vaccine | |
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| US brand name: | | PANVAC-F | |
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| Abbreviation: | | fCEA-MUC-1-TRI | |
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