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mesalamine
An agent derived from sulfasalazine, an antiinflammatory agent. Mesalamine may reduce inflammation through inhibition of cyclooxygenase and prostaglandin production. Following rectal or oral administration, only a small amount of mesalamine is absorbed; the remainder, acting topically, reduces bowel inflammation, diarrhea, rectal bleeding and stomach pain. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonym: | | mesalazine | |
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| US brand names: | | Apriso Asacol Lialda Pentasa Rowasa | |
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| Abbreviation: | | 5-ASA | |
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| Chemical structures: | | 5-amino-2-hydroxybenzoic acid 5-aminosalicylic acid | |
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