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NCI Drug Dictionary


methylmercaptopurine riboside 
A purine derivative with antineoplastic and anti-angiogenic properties. 6-methylmercaptopurine riboside (6-MMPR) inhibits amidophosphoribosyltransferase, the first committed step in de novo purine synthesis, and inhibits fibroblast growth factor-2 (FGF2)-induced cell proliferation. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonym:methylthioinosine
Abbreviations:6-MMPR
MMPR
Code names:NCI-C04784
SQ 21977
Chemical structures:6-(methylmercapto)purine ribonucleoside
6-(methylthio) inosine
6-(methylthio)purine ribonucleoside
6-(methylthio)purine riboside
6-methyl MP riboside
6-methylmercaptopurine riboside
6-methylthioinosine
9H-purine, 6-(methylthio)-9beta-D-ribofuranosyl
9H-purine, 6-(methylthio)-9-beta-D-ribofuranosyl- (8CI 9CI)
9H-purine, 6-(methylthio)-9-beta-D-ribofuranosyl-, dihydrate
beta-D-ribosyl-6-methylthiopurine
purine-6-thiol,6-methyl-9-ribofuranosyl