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indinavir sulfate
A synthetic antiviral agent. Indinavir selectively binds to the active site of human immunodeficiency virus (HIV) protease and inhibits its activity, preventing the protease-mediated cleavage of gag-pol viral polyproteins; as a result immature, noninfectious virions are produced. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| US brand name: | | Crixivan | |
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| Abbreviation: | | IDV | |
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