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NCI Drug Dictionary


taxol analogue SID 530 
An intravenous formulation containing docetaxel, a semi-synthetic, second-generation taxane derived from a compound found in the European yew tree, Taxus baccata, with potential antineoplastic activity. Taxol analogue SID 530 binds to and stabilizes tubulin, inhibiting microtubule disassembly, which results in cell-cycle arrest at the G2/M phase and cell death. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Code name:SID 530