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NCI Drug Dictionary


valganciclovir 
A synthetic prodrug of ganciclovir, a nucleoside analogue of 2'-deoxyguanosine, with antiviral activity. After phosphorylation, valganciclovir is incorporated into DNA, resulting in inhibition of viral DNA polymerase, viral DNA synthesis, and viral replication. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
US brand name:Valcyte
Abbreviation:VGCV