The search textbox has an autosuggest feature. When you enter three or more characters,
a list of up to 10 suggestions will popup under the textbox. Use the arrow keys
to move through the suggestions. To select a suggestion, hit the enter key. Using
the escape key closes the listbox and puts you back at the textbox. The radio buttons
allow you to toggle between having all search items start with or contain the text
you entered in the search box.
PEG-interferon alfa-2b
A covalent conjugate of recombinant interferon alpha, subtype 2b, and polyethylene glycol (PEG), used as an antiviral and antineoplastic agent. The biological activity of this agent is derived from its interferon alpha-2b protein moiety. Interferons alfa bind to specific cell-surface receptors, leading to the transcription and translation of genes whose protein products mediate antiviral, antiproliferative, anticancer, and immune-modulating effects. The PEG moiety lowers the clearance of interferon alpha-2b, thereby extending the duration of its therapeutic effects, but may also reduce the interferon-mediated stimulation of an immune response. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | PEG-IFN alfa-2b pegylated interferon alfa-2b polyethylene glycol IFN-A2b polyethylene glycol interferon alfa-2b SCH 54031 | |
| |||
| US brand names: | | PEG-Intron Sylatron | |
| |||
| Abbreviation: | | PEG-IFN-a 2b | |
| |||
