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octreotide acetate
The acetate salt of a synthetic long-acting cyclic octapeptide with pharmacologic properties mimicking those of the natural hormone somatostatin. Octreotide is a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Similar to somatostatin, this agent also suppresses the luteinizing hormone response to gonadotropin-releasing hormone, decreases splanchnic blood flow, and inhibits the release of serotonin, gastrin, vasoactive intestinal peptide (VIP), secretin, motilin, pancreatic polypeptide, and thyroid stimulating hormone. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonym: | | Longastatin | |
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| US brand names: | | Sandostatin Sandostatin Lar Depot | |
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| Foreign brand names: | | Longastatina Samilstin Sandostatina Sandostatine | |
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| Code name: | | SMS 201-995 | |
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| Chemical structure: | | D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2->7)-disulfide acetate | |
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