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methylprednisolone
A synthetic corticosteroid with anti-inflammatory and immunomodulating properties. Methylprednisolone binds to and activates specific nuclear receptors, resulting in altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cell populations. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | methylprednisolone acetate methylprednisolone succinate methylprednisolonum | |
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| US brand names: | | Depo-Medrol Medlone 21 Medrol Meprolone Metrocort Metypred Solu-Medrol Summicort | |
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| Foreign brand names: | | Adlone A-MethaPred Asmacortone Caberdelta M Cryosolona DepMedalone Depo Moderin Depo-Medrate Depo-Medrone Depo-Nisolone D-Med Duralone Emmetipi Esametone Firmacort Medrate Medrol Veriderm Medrone Mega-Star Metilbetasone Solubile Metypresol Metysolon Prednilem Predni-M-Tablinen Radilem Solpredone Solu Moderin Solu-Medrone Urbason Veriderm Medrol Wyacort | |
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| Abbreviation: | | MePRDL | |
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| Chemical structures: | | (6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione 6alpha-methylprednisolone | |
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