In English | En español
Questions About Cancer? 1-800-4-CANCER

NCI Drug Dictionary


basiliximab 
A recombinant, chimeric, human-murine monoclonal antibody directed against the alpha subunit of the interleukin-2 receptor (IL-2R alpha) with immunosuppressant activity. Basiliximab selectively binds to and blocks IL-2R alpha, expressed on the surface of activated T-lymphocytes, thereby preventing interleukin-2 binding and inhibiting the interleukin-2-mediated activation of lymphocytes. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
US brand name:Simulect
Code name:SDZ-CHI-621